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The map label for this gene is corC [H]

Identifier: 83721472

GI number: 83721472

Start: 670162

End: 671049

Strand: Reverse

Name: corC [H]

Synonym: BTH_I0587

Alternate gene names: 83721472

Gene position: 671049-670162 (Counterclockwise)

Preceding gene: 83718525

Following gene: 83718933

Centisome position: 17.62

GC content: 64.19

Gene sequence:

>888_bases
ATGAACGATTCGTATCCCAGTCGAAAATCCTCCGACAAACCGCATGAAAAGCGCTCGCTGCTCGAGCGCCTGACCGACTT
CATCTCGCCCGAGCCCGACTCGCGGGCCGAGCTCCTCGAAATCCTCCAGGATGCGCACGAACGCAACCTGATCGACGCCG
ATTCGCTGTCGATGATCGAGGGCGTGTTCCAGGTATCCGACCTGTGCGCACGCGACATCATGGTGCCCCGCGCGCAGATG
GACGCGCTCAACATCGCCGACAAGCCCGAGGATTTCATCCCGTTCGTGCTCGAGAAAGCGCACTCGCGGTATCCGGTATA
CGAAGACAACCGCGACAACGTGATCGGCGTGCTGCTCGCGAAGGATCTGCTGCGCTTCTACGCGGAAGAGGAATTCGACG
TGCGCGGAATGCTGCGCCCCGCCGTCTTCATCCCCGAATCGAAGCGGCTGAACGTGCTGCTGCACGATTTCCGCGTGAAC
CGCAACCATCTCGCGATCGTCGTCGACGAATACGGCGGGGTCGCGGGCCTCATCACGATCGAGGACGTGCTCGAACAGAT
CGTCGGCGACATCGAGGACGAGTACGACTTCGACGAGGAAGCCGGCAACATCATCGCCGCGCCCGACGGCCGCTACCGCG
TGCGCGCGCTGACCGAGATCGAGCAGTTCAACGAAACGTTCGGCACCGATTTCTCCGACGAGGAAGTCGACACGATCGGC
GGCCTCATCACGCACCATTTCGGCCGCGTCCCGCATCGCGGCGAGAAAGTGCGCCTGGGCGACCTGCTGTTCGAGATCCA
GCGCGGCGACGCCCGCCAGATCCACGTGCTGCTCGTGCGCCGCGCGCCGCTCGCCGGCCGGCGCAGCGGCTCGGCCGGCG
AAGACTGA

Upstream 100 bases:

>100_bases
CTTCGGCACGCGCGCATCCGCCGACACGGACGCGCCACGACCTTGGTGTATCCTTGCCTATTCCGTGACAGCGCGCTCCC
GATTCGCGGGGCGCACCACC

Downstream 100 bases:

>100_bases
CGCGCCGCCGCACTCCCCAACCCGTTCCTTCGACGCAACGCATGGCCGAACCGATCTCGACCCGCTCGCAATCGAGCGTC
TCCCCAACGGCCGCCGGCCG

Product: magnesium and cobalt efflux protein CorC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MNDSYPSRKSSDKPHEKRSLLERLTDFISPEPDSRAELLEILQDAHERNLIDADSLSMIEGVFQVSDLCARDIMVPRAQM
DALNIADKPEDFIPFVLEKAHSRYPVYEDNRDNVIGVLLAKDLLRFYAEEEFDVRGMLRPAVFIPESKRLNVLLHDFRVN
RNHLAIVVDEYGGVAGLITIEDVLEQIVGDIEDEYDFDEEAGNIIAAPDGRYRVRALTEIEQFNETFGTDFSDEEVDTIG
GLITHHFGRVPHRGEKVRLGDLLFEIQRGDARQIHVLLVRRAPLAGRRSGSAGED

Sequences:

>Translated_295_residues
MNDSYPSRKSSDKPHEKRSLLERLTDFISPEPDSRAELLEILQDAHERNLIDADSLSMIEGVFQVSDLCARDIMVPRAQM
DALNIADKPEDFIPFVLEKAHSRYPVYEDNRDNVIGVLLAKDLLRFYAEEEFDVRGMLRPAVFIPESKRLNVLLHDFRVN
RNHLAIVVDEYGGVAGLITIEDVLEQIVGDIEDEYDFDEEAGNIIAAPDGRYRVRALTEIEQFNETFGTDFSDEEVDTIG
GLITHHFGRVPHRGEKVRLGDLLFEIQRGDARQIHVLLVRRAPLAGRRSGSAGED
>Mature_295_residues
MNDSYPSRKSSDKPHEKRSLLERLTDFISPEPDSRAELLEILQDAHERNLIDADSLSMIEGVFQVSDLCARDIMVPRAQM
DALNIADKPEDFIPFVLEKAHSRYPVYEDNRDNVIGVLLAKDLLRFYAEEEFDVRGMLRPAVFIPESKRLNVLLHDFRVN
RNHLAIVVDEYGGVAGLITIEDVLEQIVGDIEDEYDFDEEAGNIIAAPDGRYRVRALTEIEQFNETFGTDFSDEEVDTIG
GLITHHFGRVPHRGEKVRLGDLLFEIQRGDARQIHVLLVRRAPLAGRRSGSAGED

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=225, Percent_Identity=30.6666666666667, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI94681046, Length=180, Percent_Identity=29.4444444444444, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI40068053, Length=182, Percent_Identity=27.4725274725275, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI40068055, Length=182, Percent_Identity=27.4725274725275, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786879, Length=280, Percent_Identity=44.6428571428571, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI145693175, Length=263, Percent_Identity=27.7566539923954, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI87082033, Length=244, Percent_Identity=27.8688524590164, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1790664, Length=229, Percent_Identity=25.764192139738, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788119, Length=231, Percent_Identity=29.4372294372294, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33497; Mature: 33497

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSYPSRKSSDKPHEKRSLLERLTDFISPEPDSRAELLEILQDAHERNLIDADSLSMIE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
GVFQVSDLCARDIMVPRAQMDALNIADKPEDFIPFVLEKAHSRYPVYEDNRDNVIGVLLA
HHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHH
KDLLRFYAEEEFDVRGMLRPAVFIPESKRLNVLLHDFRVNRNHLAIVVDEYGGVAGLITI
HHHHHHHCCCCCCHHHHCCCEEECCCCCCCEEEEEEEEECCCEEEEEEECCCCEEEEEEH
EDVLEQIVGDIEDEYDFDEEAGNIIAAPDGRYRVRALTEIEQFNETFGTDFSDEEVDTIG
HHHHHHHHHHHHHHCCCCHHCCCEEECCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHH
GLITHHFGRVPHRGEKVRLGDLLFEIQRGDARQIHVLLVRRAPLAGRRSGSAGED
HHHHHHHCCCCCCCCEEEHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MNDSYPSRKSSDKPHEKRSLLERLTDFISPEPDSRAELLEILQDAHERNLIDADSLSMIE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
GVFQVSDLCARDIMVPRAQMDALNIADKPEDFIPFVLEKAHSRYPVYEDNRDNVIGVLLA
HHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHH
KDLLRFYAEEEFDVRGMLRPAVFIPESKRLNVLLHDFRVNRNHLAIVVDEYGGVAGLITI
HHHHHHHCCCCCCHHHHCCCEEECCCCCCCEEEEEEEEECCCEEEEEEECCCCEEEEEEH
EDVLEQIVGDIEDEYDFDEEAGNIIAAPDGRYRVRALTEIEQFNETFGTDFSDEEVDTIG
HHHHHHHHHHHHHHCCCCHHCCCEEECCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHH
GLITHHFGRVPHRGEKVRLGDLLFEIQRGDARQIHVLLVRRAPLAGRRSGSAGED
HHHHHHHCCCCCCCCEEEHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]