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The map label for this gene is degS [H]

Identifier: 83721311

GI number: 83721311

Start: 243706

End: 244548

Strand: Reverse

Name: degS [H]

Synonym: BTH_I0210

Alternate gene names: 83721311

Gene position: 244548-243706 (Counterclockwise)

Preceding gene: 83720598

Following gene: 83721309

Centisome position: 6.42

GC content: 75.56

Gene sequence:

>843_bases
ATGGATACGCCGTCTATTGCGCCGTCGACTGCAAGCGTCCCCGCTTCGTCGTCGAGCGACCTCGCGTCCGAGGTCGGCAT
TCCTTTCGTTTCCCGCTCCGCCCCGCGTGCGCCCACCGCCGAGCGGCTCGGCGCGCGCGTCGCGCAGCTGTCCGCCGAGC
TCGTCGCCGCCGACGAATCCGCGCGCCGCCATCTCGCCGGCGAACTGCACGACGGCCTCGGCGCCGATCTCACCGCCGCG
CGCTTCGCGCTCGCCAACGTCGACACATGGCTGCCGGACGACGCGGCCGACGCTTGCCGGCGCGCGCTCGCGCTCGCGCA
ACAGGCGCTCGACGCCGCGACGGCCGCGAATCGCCGCCTGATCGACGGCCTGTGCACGCCCGCGCTCGAAGCCGGGCTCG
TCGGCACGCTCGCCGCATGGATCGGCGCGCACGGCGCGCGCACCGGCCTGCGCACGAGCTTCGTCTGCGCGGCCGACGCG
CGCGTCACGCAACTGTCCGCCGACGGCGCGCTCGCCGTCTTCCGCGTCGCACAGGAAGCGCTCGCAAACGTTGCCAAGCA
TGCGCACGCGTCGGCCGCCGACGTGCGGATCGACGTCGACGACACGCACCTCACGCTCGTCGTCGCCGACGACGGCGTGG
GCATCGCGACCACGCGGCGCCGCGGCGGCTACGGGCTCGGCAGCATGCGAGCACGCTGCGAGGCGCTTGGCGGCACGCTC
GAGTTCGCTTCGCCGCGCTCGGGCGGCGCGGGCACCGCGCTGCGCGCGCGCTTCGCCTGGGGCGCGCTCGTCGCCGCACG
CACGCCGGCCGCCGCGCGCAGGGTGCGCAAGGAGGCGCGATGA

Upstream 100 bases:

>100_bases
GTACGAGGCTAACGCGACGCCGGCAAATCCTGCCCGCCGCGTCGGTCGGCAATCGTTTTAGCAAGTGTCTGAATAGCTTT
CTGAATAGAAAGGGAGAGTC

Downstream 100 bases:

>100_bases
GCCTACAGATCCTGCTCGTCGACGATCATGCGATCGTCCGCCAAGGCATCCGCCAGTTGCTGATCGACCGCGGCATCGCA
CGCGAAGTCGTGGAGGCCGA

Product: sensor kinase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MDTPSIAPSTASVPASSSSDLASEVGIPFVSRSAPRAPTAERLGARVAQLSAELVAADESARRHLAGELHDGLGADLTAA
RFALANVDTWLPDDAADACRRALALAQQALDAATAANRRLIDGLCTPALEAGLVGTLAAWIGAHGARTGLRTSFVCAADA
RVTQLSADGALAVFRVAQEALANVAKHAHASAADVRIDVDDTHLTLVVADDGVGIATTRRRGGYGLGSMRARCEALGGTL
EFASPRSGGAGTALRARFAWGALVAARTPAAARRVRKEAR

Sequences:

>Translated_280_residues
MDTPSIAPSTASVPASSSSDLASEVGIPFVSRSAPRAPTAERLGARVAQLSAELVAADESARRHLAGELHDGLGADLTAA
RFALANVDTWLPDDAADACRRALALAQQALDAATAANRRLIDGLCTPALEAGLVGTLAAWIGAHGARTGLRTSFVCAADA
RVTQLSADGALAVFRVAQEALANVAKHAHASAADVRIDVDDTHLTLVVADDGVGIATTRRRGGYGLGSMRARCEALGGTL
EFASPRSGGAGTALRARFAWGALVAARTPAAARRVRKEAR
>Mature_280_residues
MDTPSIAPSTASVPASSSSDLASEVGIPFVSRSAPRAPTAERLGARVAQLSAELVAADESARRHLAGELHDGLGADLTAA
RFALANVDTWLPDDAADACRRALALAQQALDAATAANRRLIDGLCTPALEAGLVGTLAAWIGAHGARTGLRTSFVCAADA
RVTQLSADGALAVFRVAQEALANVAKHAHASAADVRIDVDDTHLTLVVADDGVGIATTRRRGGYGLGSMRARCEALGGTL
EFASPRSGGAGTALRARFAWGALVAARTPAAARRVRKEAR

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788812, Length=213, Percent_Identity=31.4553990610329, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI87082311, Length=223, Percent_Identity=30.4932735426009, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787474, Length=200, Percent_Identity=26.5, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 28630; Mature: 28630

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTPSIAPSTASVPASSSSDLASEVGIPFVSRSAPRAPTAERLGARVAQLSAELVAADES
CCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHH
ARRHLAGELHDGLGADLTAARFALANVDTWLPDDAADACRRALALAQQALDAATAANRRL
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDGLCTPALEAGLVGTLAAWIGAHGARTGLRTSFVCAADARVTQLSADGALAVFRVAQEA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHH
LANVAKHAHASAADVRIDVDDTHLTLVVADDGVGIATTRRRGGYGLGSMRARCEALGGTL
HHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHCCEE
EFASPRSGGAGTALRARFAWGALVAARTPAAARRVRKEAR
EECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MDTPSIAPSTASVPASSSSDLASEVGIPFVSRSAPRAPTAERLGARVAQLSAELVAADES
CCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHH
ARRHLAGELHDGLGADLTAARFALANVDTWLPDDAADACRRALALAQQALDAATAANRRL
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDGLCTPALEAGLVGTLAAWIGAHGARTGLRTSFVCAADARVTQLSADGALAVFRVAQEA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHH
LANVAKHAHASAADVRIDVDDTHLTLVVADDGVGIATTRRRGGYGLGSMRARCEALGGTL
HHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHCCEE
EFASPRSGGAGTALRARFAWGALVAARTPAAARRVRKEAR
EECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]