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The map label for this gene is echA8 [H]

Identifier: 83721249

GI number: 83721249

Start: 2859064

End: 2860206

Strand: Reverse

Name: echA8 [H]

Synonym: BTH_I2504

Alternate gene names: 83721249

Gene position: 2860206-2859064 (Counterclockwise)

Preceding gene: 83719484

Following gene: 83718655

Centisome position: 75.09

GC content: 71.3

Gene sequence:

>1143_bases
ATGAACGCATCCCATTCCGATTCGCCCCAGGCCGACGTTCGCGCGCATGTCGCGAACCGCATCGGCTTTCTCGAACTGAA
CCGTCCGCAGGCGCTCAACGCGCTGTCGACCGACATGATCCGCACGCTGCATCGCGCGCTCGACGCGTGGCGCGACGACG
CCGGCGTGCTCGCCGTCGTGATCCACAGTCCGCATCCGCGCGCGTTCTGCGCGGGCGGAGACGTGCGCTTCTTCCATGAT
GCGCACCGGCGCGGCGATCAAGCGTCGATCGACAGGTTCTTCATCGAAGAGTATTCGCTGAACCACGCGATCTTCACGTA
TCCGAAGCCGTATATCGCGCTGATGCACGGTGTCGTGATGGGCGGCGGAATGGGCATTTCGCAGGCGGCCAAGCGCACGG
GCGGGCTGCGCGTCGTCACCGACTCGACGAAGATGGCGATGCCGGAAACGCGCATCGGGCTCTTTCCGGACGTCGGCATG
AGCTGGTTCCTCGCGCGCACGCCGGGCGCGCTCGGCCGCTATCTCGCCGTCACGGGCGCGACGCTCGATGCGGCGAGCGC
GCTGTACGCGGGGCTCGCCGACGCCTATCTGCCGGATGCGGCGCTGCCGGCGCTCGTCGACGCGCTGCGCACCGAGCGCT
TCGACGACGGCGCGGCGGTGACGGCGCGCGTCGCGGCCGAAGCCGCGCGGCACGCGCCGGCGCCCGCGCCCGATGCGTCG
GCGCTCGCGGCCGCGCGCGCGTCGATCGACCGGCATTTCGCGCAGGCGGACGTCGCCGCGATCGCGGCGTCGCTCGACGC
CGAGCGCGACGAAGCGGTGCGCGCCGCGTGGGCCGACAAGGCGCGCGACGCGATGCGCGGCGGCTCGCTGTCGCCGCTGT
CGATGGCGGTGTCGCTCGAAGTCGTCGAGCGCGCGCGCGGCGCGACGATGGCCGACTGCCTGCGGCGCGATCTCGATCTG
ACGCGCTCGACGTTCGCGCGCGGCGATGTGATCGAAGGCGTGCGCGCGGTGATCGTCGACAAGGATCACGCGCCGAAGTG
GCGCTATCCGGCGATCGCCGACGTGTCGGCGGAGGCGGTCGCGACGATGTTCGAGAGCCCGTGGCGCGCGGACGAGCATC
CGCTCAAGGGCTTGCGCGACTGA

Upstream 100 bases:

>100_bases
ATCGTCGGGCTCGCGCTCATCATCTCGGGCGTCGCGGTGCTCAATCTCTTTTCGAAAATGCAGGCGCATTGACGGCCGCG
CCGGCCCACTTTCCATCGTC

Downstream 100 bases:

>100_bases
CGATCGCGCGGATCGCGCGCGGCGCGACGCGCGGCGGGAGATCCGACGGACCGCCGGAGGCGGCCGGCACGGCGGCGGGC
GCGATTGCCGCGAGGCTCGA

Product: 3-hydroxyisobutyryl-CoA hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MNASHSDSPQADVRAHVANRIGFLELNRPQALNALSTDMIRTLHRALDAWRDDAGVLAVVIHSPHPRAFCAGGDVRFFHD
AHRRGDQASIDRFFIEEYSLNHAIFTYPKPYIALMHGVVMGGGMGISQAAKRTGGLRVVTDSTKMAMPETRIGLFPDVGM
SWFLARTPGALGRYLAVTGATLDAASALYAGLADAYLPDAALPALVDALRTERFDDGAAVTARVAAEAARHAPAPAPDAS
ALAAARASIDRHFAQADVAAIAASLDAERDEAVRAAWADKARDAMRGGSLSPLSMAVSLEVVERARGATMADCLRRDLDL
TRSTFARGDVIEGVRAVIVDKDHAPKWRYPAIADVSAEAVATMFESPWRADEHPLKGLRD

Sequences:

>Translated_380_residues
MNASHSDSPQADVRAHVANRIGFLELNRPQALNALSTDMIRTLHRALDAWRDDAGVLAVVIHSPHPRAFCAGGDVRFFHD
AHRRGDQASIDRFFIEEYSLNHAIFTYPKPYIALMHGVVMGGGMGISQAAKRTGGLRVVTDSTKMAMPETRIGLFPDVGM
SWFLARTPGALGRYLAVTGATLDAASALYAGLADAYLPDAALPALVDALRTERFDDGAAVTARVAAEAARHAPAPAPDAS
ALAAARASIDRHFAQADVAAIAASLDAERDEAVRAAWADKARDAMRGGSLSPLSMAVSLEVVERARGATMADCLRRDLDL
TRSTFARGDVIEGVRAVIVDKDHAPKWRYPAIADVSAEAVATMFESPWRADEHPLKGLRD
>Mature_380_residues
MNASHSDSPQADVRAHVANRIGFLELNRPQALNALSTDMIRTLHRALDAWRDDAGVLAVVIHSPHPRAFCAGGDVRFFHD
AHRRGDQASIDRFFIEEYSLNHAIFTYPKPYIALMHGVVMGGGMGISQAAKRTGGLRVVTDSTKMAMPETRIGLFPDVGM
SWFLARTPGALGRYLAVTGATLDAASALYAGLADAYLPDAALPALVDALRTERFDDGAAVTARVAAEAARHAPAPAPDAS
ALAAARASIDRHFAQADVAAIAASLDAERDEAVRAAWADKARDAMRGGSLSPLSMAVSLEVVERARGATMADCLRRDLDL
TRSTFARGDVIEGVRAVIVDKDHAPKWRYPAIADVSAEAVATMFESPWRADEHPLKGLRD

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=372, Percent_Identity=33.0645161290323, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI37594469, Length=325, Percent_Identity=32.3076923076923, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI194097323, Length=185, Percent_Identity=29.7297297297297, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788682, Length=200, Percent_Identity=27, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI25144160, Length=358, Percent_Identity=37.7094972067039, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI25144157, Length=358, Percent_Identity=37.9888268156425, Blast_Score=209, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6320241, Length=348, Percent_Identity=28.735632183908, Blast_Score=135, Evalue=7e-33,
Organism=Drosophila melanogaster, GI28571730, Length=355, Percent_Identity=36.3380281690141, Blast_Score=208, Evalue=4e-54,
Organism=Drosophila melanogaster, GI28571729, Length=355, Percent_Identity=36.3380281690141, Blast_Score=208, Evalue=4e-54,
Organism=Drosophila melanogaster, GI24653139, Length=177, Percent_Identity=32.7683615819209, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 40738; Mature: 40738

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASHSDSPQADVRAHVANRIGFLELNRPQALNALSTDMIRTLHRALDAWRDDAGVLAVV
CCCCCCCCCHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
IHSPHPRAFCAGGDVRFFHDAHRRGDQASIDRFFIEEYSLNHAIFTYPKPYIALMHGVVM
EECCCCCEEECCCCEEEHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHH
GGGMGISQAAKRTGGLRVVTDSTKMAMPETRIGLFPDVGMSWFLARTPGALGRYLAVTGA
CCCCCHHHHHHHCCCEEEEECCCHHCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHEECC
TLDAASALYAGLADAYLPDAALPALVDALRTERFDDGAAVTARVAAEAARHAPAPAPDAS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHH
ALAAARASIDRHFAQADVAAIAASLDAERDEAVRAAWADKARDAMRGGSLSPLSMAVSLE
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VVERARGATMADCLRRDLDLTRSTFARGDVIEGVRAVIVDKDHAPKWRYPAIADVSAEAV
HHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHH
ATMFESPWRADEHPLKGLRD
HHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNASHSDSPQADVRAHVANRIGFLELNRPQALNALSTDMIRTLHRALDAWRDDAGVLAVV
CCCCCCCCCHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
IHSPHPRAFCAGGDVRFFHDAHRRGDQASIDRFFIEEYSLNHAIFTYPKPYIALMHGVVM
EECCCCCEEECCCCEEEHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHH
GGGMGISQAAKRTGGLRVVTDSTKMAMPETRIGLFPDVGMSWFLARTPGALGRYLAVTGA
CCCCCHHHHHHHCCCEEEEECCCHHCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHEECC
TLDAASALYAGLADAYLPDAALPALVDALRTERFDDGAAVTARVAAEAARHAPAPAPDAS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHH
ALAAARASIDRHFAQADVAAIAASLDAERDEAVRAAWADKARDAMRGGSLSPLSMAVSLE
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VVERARGATMADCLRRDLDLTRSTFARGDVIEGVRAVIVDKDHAPKWRYPAIADVSAEAV
HHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHH
ATMFESPWRADEHPLKGLRD
HHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]