Click here to switch to the map view.

The map label for this gene is ribE [H]

Identifier: 83721233

GI number: 83721233

Start: 1741200

End: 1741829

Strand: Reverse

Name: ribE [H]

Synonym: BTH_I1541

Alternate gene names: 83721233

Gene position: 1741829-1741200 (Counterclockwise)

Preceding gene: 83718892

Following gene: 83719969

Centisome position: 45.73

GC content: 66.19

Gene sequence:

>630_bases
ATGTTTACCGGAATCGTCGCGGCGGTCGGCCGCATCGAAACGATCGAGCCGATCGCCTCCTCGCCCGAGGCGGGCGTGCG
CCTCACGCTGCGCGCGGGCGCGCTCGACCTCGCCGACGTCGCGATCGGCGACAGCATCGCGATCCAGGGCGCGTGCATGA
CGGTCGTCGCGAAGACGGCCGATACGTTCGACGTCGAGGTATCGCGCGAAAGCCTGAACAAGACCGTCGGCCTCGCCGAA
GCGGGCGACGTGAATCTCGAAAAGGCGCTGCGCGCGCACGACCGCCTGGGCGGCCACATCGTATCGGGGCATGTGGACGG
GCTCGGCACCGTCACGCGCTTCGCGCCCGTGGGCGAATCGCACGAGTTGCGCGTGCTCGCGCCGCGCGAGCTCGGCCGCT
ATCTCGCGTACAAGGGCTCGATCACCGTCAACGGCGTGAGCCTCACCGTCAATTCGGTCGAAGACCGCGACGACGGCTGC
GAATTCTCGATCAACCTGATTCCTCATACGGTCGAAGTGACGACCCTGCGGCATCTGACCGCCGGCGCGAAGGTCAATCT
CGAGATTGACATGATTGCGCGGTACACCGAAAGGATGCTGTCATCGGCGTCCCCCAAGGGACGCTCGTAA

Upstream 100 bases:

>100_bases
ACAGCGTCGAGCGCGTCGGCGACGACCTGCGCATCCTCGCGCGCTTCGCGAGCGCTCACGCGAGCGCCTCCCCCACTCAT
TCATAACGGAATCCGACACG

Downstream 100 bases:

>100_bases
GTGGTTAAACCAGCGCGCGCTTCGAGTTTTATCGTCCACCGACTTACTCGGCGATCCGCTGCCGGAACCACGCCGCCAGC
GCAGCTTCGTCCAGCGCGCC

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MFTGIVAAVGRIETIEPIASSPEAGVRLTLRAGALDLADVAIGDSIAIQGACMTVVAKTADTFDVEVSRESLNKTVGLAE
AGDVNLEKALRAHDRLGGHIVSGHVDGLGTVTRFAPVGESHELRVLAPRELGRYLAYKGSITVNGVSLTVNSVEDRDDGC
EFSINLIPHTVEVTTLRHLTAGAKVNLEIDMIARYTERMLSSASPKGRS

Sequences:

>Translated_209_residues
MFTGIVAAVGRIETIEPIASSPEAGVRLTLRAGALDLADVAIGDSIAIQGACMTVVAKTADTFDVEVSRESLNKTVGLAE
AGDVNLEKALRAHDRLGGHIVSGHVDGLGTVTRFAPVGESHELRVLAPRELGRYLAYKGSITVNGVSLTVNSVEDRDDGC
EFSINLIPHTVEVTTLRHLTAGAKVNLEIDMIARYTERMLSSASPKGRS
>Mature_209_residues
MFTGIVAAVGRIETIEPIASSPEAGVRLTLRAGALDLADVAIGDSIAIQGACMTVVAKTADTFDVEVSRESLNKTVGLAE
AGDVNLEKALRAHDRLGGHIVSGHVDGLGTVTRFAPVGESHELRVLAPRELGRYLAYKGSITVNGVSLTVNSVEDRDDGC
EFSINLIPHTVEVTTLRHLTAGAKVNLEIDMIARYTERMLSSASPKGRS

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=198, Percent_Identity=31.8181818181818, Blast_Score=91, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6319733, Length=208, Percent_Identity=33.1730769230769, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22090; Mature: 22090

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVAAVGRIETIEPIASSPEAGVRLTLRAGALDLADVAIGDSIAIQGACMTVVAKTA
CCCCHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEHHEECCCCEEECCCEEEEEEECC
DTFDVEVSRESLNKTVGLAEAGDVNLEKALRAHDRLGGHIVSGHVDGLGTVTRFAPVGES
CCEEEEEEHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHCCCCCCC
HELRVLAPRELGRYLAYKGSITVNGVSLTVNSVEDRDDGCEFSINLIPHTVEVTTLRHLT
CCEEEECHHHHCCCEEEECCEEEEEEEEEEECCCCCCCCCEEEEEECCCEEEEEEEEECC
AGAKVNLEIDMIARYTERMLSSASPKGRS
CCCEEEEEHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MFTGIVAAVGRIETIEPIASSPEAGVRLTLRAGALDLADVAIGDSIAIQGACMTVVAKTA
CCCCHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEHHEECCCCEEECCCEEEEEEECC
DTFDVEVSRESLNKTVGLAEAGDVNLEKALRAHDRLGGHIVSGHVDGLGTVTRFAPVGES
CCEEEEEEHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHCCCCCCC
HELRVLAPRELGRYLAYKGSITVNGVSLTVNSVEDRDDGCEFSINLIPHTVEVTTLRHLT
CCEEEECHHHHCCCEEEECCEEEEEEEEEEECCCCCCCCCEEEEEECCCEEEEEEEEECC
AGAKVNLEIDMIARYTERMLSSASPKGRS
CCCEEEEEHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]