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The map label for this gene is hscB [H]

Identifier: 83721226

GI number: 83721226

Start: 2122943

End: 2123470

Strand: Direct

Name: hscB [H]

Synonym: BTH_I1878

Alternate gene names: 83721226

Gene position: 2122943-2123470 (Clockwise)

Preceding gene: 83719700

Following gene: 83720300

Centisome position: 55.73

GC content: 67.8

Gene sequence:

>528_bases
ATGGTTTCGCTGAAGGACAGCCACTTCGAACTCTTTCATTTGCCGGCGCAGTTCGCGCTCGACGAGCCCACGCTCGACGC
CGCGTACCGCGCCGTGCAGTCGCAGGTGCACCCGGACCGCTTCGCCGCGGCGGGCGATGCGCAAAAGCGCGTCGCGATGC
AATGGGCGACGCGCGCGAACGAGGCGTACCAGACGCTGCGCGATCCGCTCAAGCGGGCGACGTACCTGCTGCACCTGCGC
GGCGTCGATGTTGGCGCGGAGAACAACACGGCGATGGAGCCGGCGTTCCTGATGCAGCAGATGGAGTGGCGCGAGCGCAT
CGAGGATGCGGCGGCCGCGAAGAACGTCGGCGAGCTCGACGCGCTCCTCGACGAATTGCGCGACGAACGGCGCGCGCGCC
TTGCGAAGCTGGGTTCGCTGCTCGATAGCGGCTCGGACCAGGGCGCCGCCGAGGCCGTGCGGCAACTGATGTTCGTCGAG
CGCGTATCGGCCGAGATCGGCGCTCAGATCGAGCGCCTCGAACATTAA

Upstream 100 bases:

>100_bases
GGCGGGCAAGAGGCGGCGCGGGCCGCCTTTTTAATGGGCGGCACTTCGGTCGACGTCGTGCCGCAGTCGACAACGAGTTG
AGCGCGAGAGCGACTACGCG

Downstream 100 bases:

>100_bases
CCGCGCGCTTTACGCACGCGATGCAAGCGGGGCTTCGGCCCTCATCGAACACAAGAAATGGCTTTACTGCAAATTTCCGA
ACCCGGCATGGCGCCCGCGC

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MVSLKDSHFELFHLPAQFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRVAMQWATRANEAYQTLRDPLKRATYLLHLR
GVDVGAENNTAMEPAFLMQQMEWRERIEDAAAAKNVGELDALLDELRDERRARLAKLGSLLDSGSDQGAAEAVRQLMFVE
RVSAEIGAQIERLEH

Sequences:

>Translated_175_residues
MVSLKDSHFELFHLPAQFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRVAMQWATRANEAYQTLRDPLKRATYLLHLR
GVDVGAENNTAMEPAFLMQQMEWRERIEDAAAAKNVGELDALLDELRDERRARLAKLGSLLDSGSDQGAAEAVRQLMFVE
RVSAEIGAQIERLEH
>Mature_175_residues
MVSLKDSHFELFHLPAQFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRVAMQWATRANEAYQTLRDPLKRATYLLHLR
GVDVGAENNTAMEPAFLMQQMEWRERIEDAAAAKNVGELDALLDELRDERRARLAKLGSLLDSGSDQGAAEAVRQLMFVE
RVSAEIGAQIERLEH

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=164, Percent_Identity=25.609756097561, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1788876, Length=157, Percent_Identity=36.3057324840764, Blast_Score=110, Evalue=6e-26,
Organism=Drosophila melanogaster, GI161084223, Length=168, Percent_Identity=31.547619047619, Blast_Score=93, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 19629; Mature: 19629

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLKDSHFELFHLPAQFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRVAMQWATRAN
CCCCCCCCHHHHCCCHHHHCCCCHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHH
EAYQTLRDPLKRATYLLHLRGVDVGAENNTAMEPAFLMQQMEWRERIEDAAAAKNVGELD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
ALLDELRDERRARLAKLGSLLDSGSDQGAAEAVRQLMFVERVSAEIGAQIERLEH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSLKDSHFELFHLPAQFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRVAMQWATRAN
CCCCCCCCHHHHCCCHHHHCCCCHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHH
EAYQTLRDPLKRATYLLHLRGVDVGAENNTAMEPAFLMQQMEWRERIEDAAAAKNVGELD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
ALLDELRDERRARLAKLGSLLDSGSDQGAAEAVRQLMFVERVSAEIGAQIERLEH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA