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The map label for this gene is dctB [H]

Identifier: 83721206

GI number: 83721206

Start: 444128

End: 446161

Strand: Direct

Name: dctB [H]

Synonym: BTH_I0400

Alternate gene names: 83721206

Gene position: 444128-446161 (Clockwise)

Preceding gene: 83720161

Following gene: 83721461

Centisome position: 11.66

GC content: 71.58

Gene sequence:

>2034_bases
ATGTGTGCGGAGACGGCGGGGCGCGCAGCGGCGCCCGCGCCGGGCGGGGCCGGGCCGGGCGCGTCGAAGCGCGCTTCGCA
CGGCCCCGCGGCCTTTTCGGGGGGCGGCTATGCCACAATAGACGATCCTTACAGTCCGGAAGCCGTCACCGTGAAGCGCC
GCCTGCTCGTCGTTCTCGCGCTCGCCGCGATGCTCGCGGCCGCGTGCGCGCTCACGTGGACCGTCACGTGGCGGCGCGGC
ATCGCCGATCTGCGCGACAGCGCGGCGGCGCGCGTCGACCGCACGACCAACGCGCTGAAAAGCACGCTCGACCGCTACGA
ATCGCTGCCGTACCTGCTGGGCGGCCACCCGTTCGTGCAGGACGTCCTCGCCGCGCCCGGCAATCACCGCTACGTGAATC
GCGCGAACGTCTACCTCGAGGACATGAACCGCCACGCGCACGCGACGGCGACCTACGTGATCACCGCGAACGGGCTGTGC
GTCGCCGCGAGCAACTGGCGCGGCCCGGACAGCTTCACCGGCATCGGCTATCAATTCCGCCCGTACTTCATCGATGCGGT
GAAGGGCGGCACCGGCCGCTTCTTCGGGATCGGCACGATCTCGCGCGATCCCGGCTACTACATCTCGCAACCCGTGCGGC
GCGACGGCAAGATCATCGGCGTCGCGGTCGTCAAGCTCAATCTCGAGTGGTTCCAGGGCGCGGACGCGTCGGAGCCGCTC
GTCGTCGCCGACGACCACGGCGTGATCTTCCTGTCGTCGGTGCCGGCGTGGAAGTACCACACGCTCAAGCCGCTGCCGGG
GCCGATCGCGACGTCGATTCACGAGACGCGCCAGTACGCGCAGTATCCGGTCACGCCGCTGCCGCTGCGCGTCGAGCGCG
TGCTCGGGCCCGATGCGCAGATCGTGCGGATGGGCGCGGGGCGGCGTTCGCCGCGCTATCTCGCGACGCGCCGCCTGCTC
GGCGAGCCCGACTGGCAGCTCGTCACGCTCGCGCCGATCGAGCCCGTCGACGTCGACGCGCGCAATGCGACGATCGTCAC
CGCGTTCGGCTTCGTGTCGCTCGGCCTGCTTGCGTTCTACTGGCGCGCGCGCCGCGCGCGCGTGCAGGAGATGCTGCGCA
GCCGCGTGCTGCTGCAAAGCGCGTATGCGGAGCTGAACCGGCGCGTCGAGGAGCGCACGGCCGATCTGTCGCAGGCGAAC
GCGCGGCTCAAGAAGGAAGTCGGCGAGCGCATCCGCGCGGAGCAGGAGCTGCGCGCCGCGCACGACGAGCTCGTTCAGGC
GAGCAAGCTCGCCGCGCTCGGCCAGATGGCGGCCGGCATCACGCACGAGCTGAACCAGCCGCTCGCCGCGCTGCGCAGCT
TCTCCGACAACACGCGCGTGCTGCTCGACCGCGGCGAGCAGGCGGCCGCGCGCGAGAATCTCGAGGCGATCGCGGCGCTC
ACCGAGCGGATGGGCAAGATCACGAATCAGCTGAAGCTGTTCGTCGGGCGCGCGAAGCCGCGCAACGAGCGGGCGCACGT
CGCGCGCGCGCTGCGCAACGCGCTCGCGTTGCTCGAGGAGCGGATGAGAGGCGTCGAGCTCGCGATCGTGCTGCGCGACG
AGACGCGCGATCCCGTCGAAGCCGTGCGCTTCGATCCGTCGCGGGATGAGCCGGCGCTCGTCGCGCGCTGCGAGGATCTG
CGGCTCGAGCAGGTGCTCATCAATCTGCTCGGCAACGCGCTCGACGCGGTCGCGGCGGCGGCCGCGCCGCGCATCGACGT
GACGATCGATGCGACGGCCGCGACGCTTGCGATCGCCGTGCGCGACAATGGGCCGGGGATCGCGCCGGAATCGCTCGCGC
GGCTGTTCGAGCCGTTCTTCACGACGAAGGAAATGGGGCGCGGGCTCGGGCTCGGCCTCGCGATCTCGTCGTCGATCGCG
CGCGACGCGGGCGGCTCGCTCACCGCGCGCAACGCGCCGGCGGGCGGCGCGGAGTTCGTCTTGACGCTGCGCCGCGCGCG
CACGCATCATCCGGACACTTCCGCCGCGAGCTGA

Upstream 100 bases:

>100_bases
TCGTGTCCGCGTGGGAGAAGGAGCTCGACCGCGCGAAGCTGCACGCGGCGCTTTCGGGCAACGGCAAGGCGGCCGCGGGC
GAAGCCGCGCGGGTCTGACG

Downstream 100 bases:

>100_bases
GCGCGCGTTTCGCGCGCGGCCCGCGTCAGCATCATGGGGTGACAGAAGATGGCGAACCGCCTGCAAGTGATCTACATCGA
AGACGACGAGCTCGTGCGCC

Product: C4-dicarboxylate transport sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 677; Mature: 677

Protein sequence:

>677_residues
MCAETAGRAAAPAPGGAGPGASKRASHGPAAFSGGGYATIDDPYSPEAVTVKRRLLVVLALAAMLAAACALTWTVTWRRG
IADLRDSAAARVDRTTNALKSTLDRYESLPYLLGGHPFVQDVLAAPGNHRYVNRANVYLEDMNRHAHATATYVITANGLC
VAASNWRGPDSFTGIGYQFRPYFIDAVKGGTGRFFGIGTISRDPGYYISQPVRRDGKIIGVAVVKLNLEWFQGADASEPL
VVADDHGVIFLSSVPAWKYHTLKPLPGPIATSIHETRQYAQYPVTPLPLRVERVLGPDAQIVRMGAGRRSPRYLATRRLL
GEPDWQLVTLAPIEPVDVDARNATIVTAFGFVSLGLLAFYWRARRARVQEMLRSRVLLQSAYAELNRRVEERTADLSQAN
ARLKKEVGERIRAEQELRAAHDELVQASKLAALGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIAAL
TERMGKITNQLKLFVGRAKPRNERAHVARALRNALALLEERMRGVELAIVLRDETRDPVEAVRFDPSRDEPALVARCEDL
RLEQVLINLLGNALDAVAAAAAPRIDVTIDATAATLAIAVRDNGPGIAPESLARLFEPFFTTKEMGRGLGLGLAISSSIA
RDAGGSLTARNAPAGGAEFVLTLRRARTHHPDTSAAS

Sequences:

>Translated_677_residues
MCAETAGRAAAPAPGGAGPGASKRASHGPAAFSGGGYATIDDPYSPEAVTVKRRLLVVLALAAMLAAACALTWTVTWRRG
IADLRDSAAARVDRTTNALKSTLDRYESLPYLLGGHPFVQDVLAAPGNHRYVNRANVYLEDMNRHAHATATYVITANGLC
VAASNWRGPDSFTGIGYQFRPYFIDAVKGGTGRFFGIGTISRDPGYYISQPVRRDGKIIGVAVVKLNLEWFQGADASEPL
VVADDHGVIFLSSVPAWKYHTLKPLPGPIATSIHETRQYAQYPVTPLPLRVERVLGPDAQIVRMGAGRRSPRYLATRRLL
GEPDWQLVTLAPIEPVDVDARNATIVTAFGFVSLGLLAFYWRARRARVQEMLRSRVLLQSAYAELNRRVEERTADLSQAN
ARLKKEVGERIRAEQELRAAHDELVQASKLAALGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIAAL
TERMGKITNQLKLFVGRAKPRNERAHVARALRNALALLEERMRGVELAIVLRDETRDPVEAVRFDPSRDEPALVARCEDL
RLEQVLINLLGNALDAVAAAAAPRIDVTIDATAATLAIAVRDNGPGIAPESLARLFEPFFTTKEMGRGLGLGLAISSSIA
RDAGGSLTARNAPAGGAEFVLTLRRARTHHPDTSAAS
>Mature_677_residues
MCAETAGRAAAPAPGGAGPGASKRASHGPAAFSGGGYATIDDPYSPEAVTVKRRLLVVLALAAMLAAACALTWTVTWRRG
IADLRDSAAARVDRTTNALKSTLDRYESLPYLLGGHPFVQDVLAAPGNHRYVNRANVYLEDMNRHAHATATYVITANGLC
VAASNWRGPDSFTGIGYQFRPYFIDAVKGGTGRFFGIGTISRDPGYYISQPVRRDGKIIGVAVVKLNLEWFQGADASEPL
VVADDHGVIFLSSVPAWKYHTLKPLPGPIATSIHETRQYAQYPVTPLPLRVERVLGPDAQIVRMGAGRRSPRYLATRRLL
GEPDWQLVTLAPIEPVDVDARNATIVTAFGFVSLGLLAFYWRARRARVQEMLRSRVLLQSAYAELNRRVEERTADLSQAN
ARLKKEVGERIRAEQELRAAHDELVQASKLAALGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIAAL
TERMGKITNQLKLFVGRAKPRNERAHVARALRNALALLEERMRGVELAIVLRDETRDPVEAVRFDPSRDEPALVARCEDL
RLEQVLINLLGNALDAVAAAAAPRIDVTIDATAATLAIAVRDNGPGIAPESLARLFEPFFTTKEMGRGLGLGLAISSSIA
RDAGGSLTARNAPAGGAEFVLTLRRARTHHPDTSAAS

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=284, Percent_Identity=31.3380281690141, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790436, Length=254, Percent_Identity=28.740157480315, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787894, Length=330, Percent_Identity=28.1818181818182, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786912, Length=294, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI145693157, Length=278, Percent_Identity=26.978417266187, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI87081816, Length=290, Percent_Identity=29.3103448275862, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1789149, Length=286, Percent_Identity=24.4755244755245, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73255; Mature: 73255

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50109 HIS_KIN ; PS00210 HEMOCYANIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCAETAGRAAAPAPGGAGPGASKRASHGPAAFSGGGYATIDDPYSPEAVTVKRRLLVVLA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHH
LAAMLAAACALTWTVTWRRGIADLRDSAAARVDRTTNALKSTLDRYESLPYLLGGHPFVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHH
DVLAAPGNHRYVNRANVYLEDMNRHAHATATYVITANGLCVAASNWRGPDSFTGIGYQFR
HHHCCCCCCCEEEHHHEEHHHCCCCCCCEEEEEEEECCEEEEECCCCCCCCCCCCCEEEC
PYFIDAVKGGTGRFFGIGTISRDPGYYISQPVRRDGKIIGVAVVKLNLEWFQGADASEPL
CEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEHHHCCCCCCCCE
VVADDHGVIFLSSVPAWKYHTLKPLPGPIATSIHETRQYAQYPVTPLPLRVERVLGPDAQ
EEECCCCEEEEECCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHH
IVRMGAGRRSPRYLATRRLLGEPDWQLVTLAPIEPVDVDARNATIVTAFGFVSLGLLAFY
EEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
WRARRARVQEMLRSRVLLQSAYAELNRRVEERTADLSQANARLKKEVGERIRAEQELRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDELVQASKLAALGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHH
TERMGKITNQLKLFVGRAKPRNERAHVARALRNALALLEERMRGVELAIVLRDETRDPVE
HHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHH
AVRFDPSRDEPALVARCEDLRLEQVLINLLGNALDAVAAAAAPRIDVTIDATAATLAIAV
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEE
RDNGPGIAPESLARLFEPFFTTKEMGRGLGLGLAISSSIARDAGGSLTARNAPAGGAEFV
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCHHHH
LTLRRARTHHPDTSAAS
HHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MCAETAGRAAAPAPGGAGPGASKRASHGPAAFSGGGYATIDDPYSPEAVTVKRRLLVVLA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHH
LAAMLAAACALTWTVTWRRGIADLRDSAAARVDRTTNALKSTLDRYESLPYLLGGHPFVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHH
DVLAAPGNHRYVNRANVYLEDMNRHAHATATYVITANGLCVAASNWRGPDSFTGIGYQFR
HHHCCCCCCCEEEHHHEEHHHCCCCCCCEEEEEEEECCEEEEECCCCCCCCCCCCCEEEC
PYFIDAVKGGTGRFFGIGTISRDPGYYISQPVRRDGKIIGVAVVKLNLEWFQGADASEPL
CEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEHHHCCCCCCCCE
VVADDHGVIFLSSVPAWKYHTLKPLPGPIATSIHETRQYAQYPVTPLPLRVERVLGPDAQ
EEECCCCEEEEECCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHH
IVRMGAGRRSPRYLATRRLLGEPDWQLVTLAPIEPVDVDARNATIVTAFGFVSLGLLAFY
EEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
WRARRARVQEMLRSRVLLQSAYAELNRRVEERTADLSQANARLKKEVGERIRAEQELRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDELVQASKLAALGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHH
TERMGKITNQLKLFVGRAKPRNERAHVARALRNALALLEERMRGVELAIVLRDETRDPVE
HHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHH
AVRFDPSRDEPALVARCEDLRLEQVLINLLGNALDAVAAAAAPRIDVTIDATAATLAIAV
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEE
RDNGPGIAPESLARLFEPFFTTKEMGRGLGLGLAISSSIARDAGGSLTARNAPAGGAEFV
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCHHHH
LTLRRARTHHPDTSAAS
HHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3671068 [H]