Click here to switch to the map view.

The map label for this gene is cbl [H]

Identifier: 83721158

GI number: 83721158

Start: 2834482

End: 2835408

Strand: Reverse

Name: cbl [H]

Synonym: BTH_I2476

Alternate gene names: 83721158

Gene position: 2835408-2834482 (Counterclockwise)

Preceding gene: 83718501

Following gene: 83720811

Centisome position: 74.44

GC content: 66.24

Gene sequence:

>927_bases
ATGAATTTCCAACAGTTGCGCTTCGTGCGCGAAGCGGTGCGGCAGAACATGAACCTGACGGAAGTCGCGAACGTGCTGTA
CACGTCGCAGTCGGGCGTGTCGAAGCAGATCAAGGATCTGGAGGACGAACTCGGCGTCGACATCTTCATTCGCCGGGGCA
AGCGCCTCACGGGGCTGACCGAGCCCGGCAAGGCGGTCCATCAACTGATCGAGCGGATGCTGCTCGACGCGGAGAACCTG
CGCCGCGTCGCGCGCCAGTTCGCGGACCAGGACAGCGGCCACCTCGTCGTCGCGACGACGCACACGCAGGCGCGCTACGC
GCTGCCGAAGGTGATCCGCCAGTTCACGGAGGTCTATCCGAAGGTGCATCTCGCGCTGCGCCAGGGCAGCCCGCAGCAGA
TCGCGCAGATGATCCTGAACGGCGAGGCGGATCTCGGCATCTCGACCGAGGCGCTCGACCGCTATCCGGACATCGTCACG
TTTCCGTGCTATTCGTGGCATCACGTCGTCGTCGTGCCGAAGGGGCATCCGCTCGTCGGCCGCGAGAGCGTGACGCTCGA
CGACATCGCCGAATATCCGATCATCACGTACGACCAGGACTTCACCGGCCGCTCGCACATCGACCAGGCGTTCGCGGATG
CGGGCGCGGTGCCGGACGTCGTGCTCACGGCGATCGACGCGGACGTGATCAAGACCTACGTCGAGCTCGGGATGGGGATC
GGCGTCGTCGCCGCGATGGCGTATGACGCGCAGCGGGACACGGGGCTCGTCGCGCTCGACACGCAGCATCTGTTCGAGGC
GAGCACGACGCGCGTCGGCCTGCGTCGCGGCGCGTTCCTGCGCGCGTATGCGTACCGGCTGATCGAGATGTTCGCGCCGC
ATCTGTCCGAAGGCGAGATCGCCGGGCAATTGCGGGAAGCGGCCTGA

Upstream 100 bases:

>100_bases
GCGCGGTGCGCGTGTTTCCGGCGCGCTGACGGCGCTCCGGCGAGCGGCGCGCGCATGCGGATTTCACAGACCAACAAAGA
CATCGCCTGAGAGGCTACCC

Downstream 100 bases:

>100_bases
CCGGGCCGGGGTGTGAGTCGGGTATGAGTCGAGCGTGAGCGACGGCGCGGTTCGGTTCGGCCTTCGCGCTTTTCGCCGCC
ACGCGCCGCCGTTCGATTTC

Product: transcriptional regulator CysB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLTEPGKAVHQLIERMLLDAENL
RRVARQFADQDSGHLVVATTHTQARYALPKVIRQFTEVYPKVHLALRQGSPQQIAQMILNGEADLGISTEALDRYPDIVT
FPCYSWHHVVVVPKGHPLVGRESVTLDDIAEYPIITYDQDFTGRSHIDQAFADAGAVPDVVLTAIDADVIKTYVELGMGI
GVVAAMAYDAQRDTGLVALDTQHLFEASTTRVGLRRGAFLRAYAYRLIEMFAPHLSEGEIAGQLREAA

Sequences:

>Translated_308_residues
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLTEPGKAVHQLIERMLLDAENL
RRVARQFADQDSGHLVVATTHTQARYALPKVIRQFTEVYPKVHLALRQGSPQQIAQMILNGEADLGISTEALDRYPDIVT
FPCYSWHHVVVVPKGHPLVGRESVTLDDIAEYPIITYDQDFTGRSHIDQAFADAGAVPDVVLTAIDADVIKTYVELGMGI
GVVAAMAYDAQRDTGLVALDTQHLFEASTTRVGLRRGAFLRAYAYRLIEMFAPHLSEGEIAGQLREAA
>Mature_308_residues
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLTEPGKAVHQLIERMLLDAENL
RRVARQFADQDSGHLVVATTHTQARYALPKVIRQFTEVYPKVHLALRQGSPQQIAQMILNGEADLGISTEALDRYPDIVT
FPCYSWHHVVVVPKGHPLVGRESVTLDDIAEYPIITYDQDFTGRSHIDQAFADAGAVPDVVLTAIDADVIKTYVELGMGI
GVVAAMAYDAQRDTGLVALDTQHLFEASTTRVGLRRGAFLRAYAYRLIEMFAPHLSEGEIAGQLREAA

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=308, Percent_Identity=54.2207792207792, Blast_Score=350, Evalue=5e-98,
Organism=Escherichia coli, GI1787530, Length=296, Percent_Identity=50, Blast_Score=315, Evalue=3e-87,
Organism=Escherichia coli, GI157672245, Length=225, Percent_Identity=31.1111111111111, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788887, Length=259, Percent_Identity=29.3436293436293, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1790399, Length=293, Percent_Identity=25.2559726962457, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788481, Length=258, Percent_Identity=26.3565891472868, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI2367136, Length=241, Percent_Identity=24.0663900414938, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789204, Length=246, Percent_Identity=25.609756097561, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI145693105, Length=237, Percent_Identity=24.0506329113924, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787806, Length=282, Percent_Identity=23.4042553191489, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1790208, Length=224, Percent_Identity=27.6785714285714, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787601, Length=189, Percent_Identity=27.5132275132275, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87082132, Length=122, Percent_Identity=34.4262295081967, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790262, Length=258, Percent_Identity=24.4186046511628, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34287; Mature: 34287

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCC
EPGKAVHQLIERMLLDAENLRRVARQFADQDSGHLVVATTHTQARYALPKVIRQFTEVYP
CCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
KVHLALRQGSPQQIAQMILNGEADLGISTEALDRYPDIVTFPCYSWHHVVVVPKGHPLVG
HHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEECCCCCEEEEEEECCCCCCC
RESVTLDDIAEYPIITYDQDFTGRSHIDQAFADAGAVPDVVLTAIDADVIKTYVELGMGI
CCCCCHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCH
GVVAAMAYDAQRDTGLVALDTQHLFEASTTRVGLRRGAFLRAYAYRLIEMFAPHLSEGEI
HHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AGQLREAA
HHHHHHCC
>Mature Secondary Structure
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCC
EPGKAVHQLIERMLLDAENLRRVARQFADQDSGHLVVATTHTQARYALPKVIRQFTEVYP
CCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
KVHLALRQGSPQQIAQMILNGEADLGISTEALDRYPDIVTFPCYSWHHVVVVPKGHPLVG
HHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEECCCCCEEEEEEECCCCCCC
RESVTLDDIAEYPIITYDQDFTGRSHIDQAFADAGAVPDVVLTAIDADVIKTYVELGMGI
CCCCCHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCH
GVVAAMAYDAQRDTGLVALDTQHLFEASTTRVGLRRGAFLRAYAYRLIEMFAPHLSEGEI
HHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AGQLREAA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529872; 9097040; 9278503 [H]