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The map label for this gene is ybdL [H]

Identifier: 83721131

GI number: 83721131

Start: 1229069

End: 1230241

Strand: Reverse

Name: ybdL [H]

Synonym: BTH_I1088

Alternate gene names: 83721131

Gene position: 1230241-1229069 (Counterclockwise)

Preceding gene: 83720764

Following gene: 83718853

Centisome position: 32.3

GC content: 66.67

Gene sequence:

>1173_bases
ATGAACGCACCGCACGACATGCCTACGACGCCCACTCTCCTCTCGCGCCTGCCCGACGTCGGCACGACGATTTTCACGGT
CATGAGCGCGCTCGCCGCGGAAAAGGGCGCGGTCAATCTCGGCCAGGGCTTTCCCGATTTCGATTGCGATCCGCGCATCG
TGGACGCGGTCGCTCGCGCGATGCGCGACGGCCGCAACCAGTATCCGCCGATGGCGGGCATCGCGCCGCTGCGTGAAGCG
ATCGCCGACAAGATCGCGCGGCTCTACGGCCACCGCTACGATGCCGCGACCGAGATCACCGTGACGGCGGGCGCGACGCA
GGCGCTCCTGACCGCGATCCTGTGCGCGGTGCATCCGGGCGACGAGGTGATCGTGATCGAGCCGACCTACGACAGCTACC
TGCCGTCGATCGAGCTGGCGGGCGCGACGCCCGTGTTCGTCACGCTGAACGCGCCCGACTACGCGATTCCGTTCGACAAG
CTCGCCGCGGCGATCACGCCGAAGACGCGTGCGATCCTGATCAACACGCCGCACAATCCGACGGGCACCGTGTGGCGCGA
GGCTGACATGCGCGCGCTCGCGGACATCGTGCGCGGCACCCATCTGCTGATCGTGTCCGACGAGGTCTACGAGCACATGG
TCTACGACGGCACGCGCCACGAGAGCGTCGCCCGCTATCCGGAGCTCGCCGCGCGCAGCATCGTCGTGTCGAGCTTCGGC
AAGACCTTCCACGTGACGGGCTGGAAGGTCGGCTACGTCGCCGCGCCCGCGCCGCTCACGGCGGAGTTCCGCAAGGTGCA
CCAGTTCAACGTGTTCACGGTCAACACGCCGATGCAGTTCGGCCTCGCCGATTACCTGCGCGACCCCGAGCCGTATCTGA
CGCTGCCCGCGTTCTATCAGAAGAAGCGCGACTTCTTCCGCGCGGGGCTCGCGAACACGCGCTTCAAGTTGCTGCCTTGC
GCGGGCACGTATTTCCAGTGTGTCGATTATTCGACGATCAGCGATCTGCCGGAAGCGGAGTTCGCGAAATGGCTGACGAC
CGAGATCGGCGTCGCCGCGATTCCGGTGTCGGCGTTCTATCACGAGCCGCATGAATCGGGCGTCGTGCGCTTCTGCTTCG
CGAAGCGCGAAGACACGCTCGCCACCGCGCTCGAACGGCTCGCGCGCCTGTAG

Upstream 100 bases:

>100_bases
CGCGCAACCCGCGCCGTTCGCCGCCAGCGCGCTCGCGACCAACGCCTCCAAGCCGGCGTAAGCGACGCGCCCGCCCCAAC
CCCTTTTTGCGCCAGCCACG

Downstream 100 bases:

>100_bases
CCCTCGGCAACGCGGCGCAGGCGTCATGCGCGCCGCCGCGAAACCGCCCGCTCGACGCGCCGCGCCAAGACTCGATCGGG
CAGCCGGTCGATCCATCGAG

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MNAPHDMPTTPTLLSRLPDVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVARAMRDGRNQYPPMAGIAPLREA
IADKIARLYGHRYDAATEITVTAGATQALLTAILCAVHPGDEVIVIEPTYDSYLPSIELAGATPVFVTLNAPDYAIPFDK
LAAAITPKTRAILINTPHNPTGTVWREADMRALADIVRGTHLLIVSDEVYEHMVYDGTRHESVARYPELAARSIVVSSFG
KTFHVTGWKVGYVAAPAPLTAEFRKVHQFNVFTVNTPMQFGLADYLRDPEPYLTLPAFYQKKRDFFRAGLANTRFKLLPC
AGTYFQCVDYSTISDLPEAEFAKWLTTEIGVAAIPVSAFYHEPHESGVVRFCFAKREDTLATALERLARL

Sequences:

>Translated_390_residues
MNAPHDMPTTPTLLSRLPDVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVARAMRDGRNQYPPMAGIAPLREA
IADKIARLYGHRYDAATEITVTAGATQALLTAILCAVHPGDEVIVIEPTYDSYLPSIELAGATPVFVTLNAPDYAIPFDK
LAAAITPKTRAILINTPHNPTGTVWREADMRALADIVRGTHLLIVSDEVYEHMVYDGTRHESVARYPELAARSIVVSSFG
KTFHVTGWKVGYVAAPAPLTAEFRKVHQFNVFTVNTPMQFGLADYLRDPEPYLTLPAFYQKKRDFFRAGLANTRFKLLPC
AGTYFQCVDYSTISDLPEAEFAKWLTTEIGVAAIPVSAFYHEPHESGVVRFCFAKREDTLATALERLARL
>Mature_390_residues
MNAPHDMPTTPTLLSRLPDVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVARAMRDGRNQYPPMAGIAPLREA
IADKIARLYGHRYDAATEITVTAGATQALLTAILCAVHPGDEVIVIEPTYDSYLPSIELAGATPVFVTLNAPDYAIPFDK
LAAAITPKTRAILINTPHNPTGTVWREADMRALADIVRGTHLLIVSDEVYEHMVYDGTRHESVARYPELAARSIVVSSFG
KTFHVTGWKVGYVAAPAPLTAEFRKVHQFNVFTVNTPMQFGLADYLRDPEPYLTLPAFYQKKRDFFRAGLANTRFKLLPC
AGTYFQCVDYSTISDLPEAEFAKWLTTEIGVAAIPVSAFYHEPHESGVVRFCFAKREDTLATALERLARL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=401, Percent_Identity=35.9102244389027, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI56713256, Length=401, Percent_Identity=35.9102244389027, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI95147551, Length=409, Percent_Identity=35.2078239608802, Blast_Score=231, Evalue=7e-61,
Organism=Homo sapiens, GI169881279, Length=409, Percent_Identity=35.2078239608802, Blast_Score=231, Evalue=7e-61,
Organism=Homo sapiens, GI169881281, Length=408, Percent_Identity=30.6372549019608, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI4507369, Length=217, Percent_Identity=26.2672811059908, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1786816, Length=377, Percent_Identity=51.9893899204244, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1788722, Length=390, Percent_Identity=26.4102564102564, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788627, Length=224, Percent_Identity=28.125, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787710, Length=293, Percent_Identity=27.3037542662116, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71994472, Length=404, Percent_Identity=35.3960396039604, Blast_Score=227, Evalue=8e-60,
Organism=Caenorhabditis elegans, GI71994476, Length=416, Percent_Identity=34.8557692307692, Blast_Score=226, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17567369, Length=399, Percent_Identity=32.3308270676692, Blast_Score=198, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI17567663, Length=206, Percent_Identity=26.6990291262136, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=397, Percent_Identity=31.4861460957179, Blast_Score=193, Evalue=4e-50,
Organism=Drosophila melanogaster, GI28573069, Length=411, Percent_Identity=35.036496350365, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24646114, Length=411, Percent_Identity=35.036496350365, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI28573067, Length=411, Percent_Identity=35.036496350365, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI28573065, Length=411, Percent_Identity=35.036496350365, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI18859735, Length=205, Percent_Identity=30.7317073170732, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42896; Mature: 42896

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPHDMPTTPTLLSRLPDVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVARA
CCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
MRDGRNQYPPMAGIAPLREAIADKIARLYGHRYDAATEITVTAGATQALLTAILCAVHPG
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCC
DEVIVIEPTYDSYLPSIELAGATPVFVTLNAPDYAIPFDKLAAAITPKTRAILINTPHNP
CEEEEEECCHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCCCEEEEECCCCC
TGTVWREADMRALADIVRGTHLLIVSDEVYEHMVYDGTRHESVARYPELAARSIVVSSFG
CCCEEHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
KTFHVTGWKVGYVAAPAPLTAEFRKVHQFNVFTVNTPMQFGLADYLRDPEPYLTLPAFYQ
CEEEECCEEEEEEECCCCCHHHHHHHHEEEEEEECCCHHHCHHHHHCCCCCCEECHHHHH
KKRDFFRAGLANTRFKLLPCAGTYFQCVDYSTISDLPEAEFAKWLTTEIGVAAIPVSAFY
HHHHHHHHCCCCCCEEEEECCCCCEEEECCHHHHCCCHHHHHHHHHHHCCHHEEEHHHHH
HEPHESGVVRFCFAKREDTLATALERLARL
CCCCCCCEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNAPHDMPTTPTLLSRLPDVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVARA
CCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
MRDGRNQYPPMAGIAPLREAIADKIARLYGHRYDAATEITVTAGATQALLTAILCAVHPG
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCC
DEVIVIEPTYDSYLPSIELAGATPVFVTLNAPDYAIPFDKLAAAITPKTRAILINTPHNP
CEEEEEECCHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCCCEEEEECCCCC
TGTVWREADMRALADIVRGTHLLIVSDEVYEHMVYDGTRHESVARYPELAARSIVVSSFG
CCCEEHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
KTFHVTGWKVGYVAAPAPLTAEFRKVHQFNVFTVNTPMQFGLADYLRDPEPYLTLPAFYQ
CEEEECCEEEEEEECCCCCHHHHHHHHEEEEEEECCCHHHCHHHHHCCCCCCEECHHHHH
KKRDFFRAGLANTRFKLLPCAGTYFQCVDYSTISDLPEAEFAKWLTTEIGVAAIPVSAFY
HHHHHHHHCCCCCCEEEEECCCCCEEEECCHHHHCCCHHHHHHHHHHHCCHHEEEHHHHH
HEPHESGVVRFCFAKREDTLATALERLARL
CCCCCCCEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]