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The map label for this gene is lpxK [H]

Identifier: 83721049

GI number: 83721049

Start: 851138

End: 852178

Strand: Reverse

Name: lpxK [H]

Synonym: BTH_I0742

Alternate gene names: 83721049

Gene position: 852178-851138 (Counterclockwise)

Preceding gene: 83721468

Following gene: 83718675

Centisome position: 22.37

GC content: 73.87

Gene sequence:

>1041_bases
GTGTCTCGCGTCATGAGCGCTCGGCCGGGATTGCTCGCGCGCGCCGAAGCGCGCCTGACCCGCGAGTGGCAGCGCCGCGG
CGCACTCGCATGGGCGCTCACGCCCTTCGCATGCGCGTTCGGCGCGATCGCCGCGCTGCGCCGCGCCGCCTATGCGCGCG
GCTGGAAGGCGCGCGTCGACTGCGGCGTGCCCGTCGTCGTCGTCGGCAACGTGACGGTCGGCGGCACCGGCAAGACGCCC
ACCGTGATCGCGCTCGTCGACGCGCTGCGCGCCGCGGGCTTCACGCCCGGCGTCGTGTCGCGCGGCTACGGCGCGAAGAT
CGTCGCGCCGACCGCGGTCACGCCCGCGTCGGCGCCGCAGCAGGCAGGCGACGAGCCGCTCCTGATCGCGCGCCGCACGC
TCGCGCCCGTGTGGGTGTGCCCGGACCGCGTCGCGGCCGTGCGCGCGCTGAAGGCCGCGCACCCCGAAGTCGACGTCGTC
GTGAGCGACGACGGCCTGCAGCACTACCGGCTCGCGCGCGCAGTCGAGATCGTCGTGTTCGACCATCGCCTCGGCGGCAA
CGGCTTCCTGCTGCCGGCCGGGCCGCTGCGCGAGCCGCTGTCGCGCCGCCGCGACGCAACGCTCGTCAACGATCCGTACA
GCCGCGCGCTGCCGCCGTGGCCCGACACGTTCGCGCTGTCGCTCGCGCCCGGCGACGCATGGCATCTCGCCCGGCCGTCG
CGCCGCAAGCCGCTCGCGCAATTCGCGGGCGAGCGCGTGCTCGCGGCGGCGGGCATCGGCGCGCCGGAGCGCTTCTTCGC
GACGCTGCGCGCGGCGGGCGTCACGCCGGCGACGCGCGCGCTGCCCGATCACTACGCGTTCGCCACGAACCCGTTCGTCG
ACGATCATTTCGACGCGATCCTGATCACCGAGAAGGATGCAGTAAAATTGGGGACTTCGTGGCGCGACGCTCGCATCTGG
GTCGTGCCGGTCGAGGCCGCGCTCGATCCCCGCCTTATCGCTCTCGTTGTGGAGAAACTCCGTGGACGCACGTCTGCTTG
A

Upstream 100 bases:

>100_bases
CTAGAGTGCCGCCTTTCGAAGAGAAGACCGCGCGGCCGCCCGCCGCCATCCGGAGAAACGTGTTGACGAATCCGTCCTCA
GCCGCGCCGCGCGGCGTCTC

Downstream 100 bases:

>100_bases
AATCCTCGTCTGCCCGGTTTGCAAGGGCCCGCTCCACTACGACCGCGGCGCGCAGGAGCTCGTCTGCAATGCCGACAAGC
TCGCGTATCCGATCCGCGAC

Product: tetraacyldisaccharide 4'-kinase

Products: NA

Alternate protein names: Lipid A 4'-kinase [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MSRVMSARPGLLARAEARLTREWQRRGALAWALTPFACAFGAIAALRRAAYARGWKARVDCGVPVVVVGNVTVGGTGKTP
TVIALVDALRAAGFTPGVVSRGYGAKIVAPTAVTPASAPQQAGDEPLLIARRTLAPVWVCPDRVAAVRALKAAHPEVDVV
VSDDGLQHYRLARAVEIVVFDHRLGGNGFLLPAGPLREPLSRRRDATLVNDPYSRALPPWPDTFALSLAPGDAWHLARPS
RRKPLAQFAGERVLAAAGIGAPERFFATLRAAGVTPATRALPDHYAFATNPFVDDHFDAILITEKDAVKLGTSWRDARIW
VVPVEAALDPRLIALVVEKLRGRTSA

Sequences:

>Translated_346_residues
MSRVMSARPGLLARAEARLTREWQRRGALAWALTPFACAFGAIAALRRAAYARGWKARVDCGVPVVVVGNVTVGGTGKTP
TVIALVDALRAAGFTPGVVSRGYGAKIVAPTAVTPASAPQQAGDEPLLIARRTLAPVWVCPDRVAAVRALKAAHPEVDVV
VSDDGLQHYRLARAVEIVVFDHRLGGNGFLLPAGPLREPLSRRRDATLVNDPYSRALPPWPDTFALSLAPGDAWHLARPS
RRKPLAQFAGERVLAAAGIGAPERFFATLRAAGVTPATRALPDHYAFATNPFVDDHFDAILITEKDAVKLGTSWRDARIW
VVPVEAALDPRLIALVVEKLRGRTSA
>Mature_345_residues
SRVMSARPGLLARAEARLTREWQRRGALAWALTPFACAFGAIAALRRAAYARGWKARVDCGVPVVVVGNVTVGGTGKTPT
VIALVDALRAAGFTPGVVSRGYGAKIVAPTAVTPASAPQQAGDEPLLIARRTLAPVWVCPDRVAAVRALKAAHPEVDVVV
SDDGLQHYRLARAVEIVVFDHRLGGNGFLLPAGPLREPLSRRRDATLVNDPYSRALPPWPDTFALSLAPGDAWHLARPSR
RKPLAQFAGERVLAAAGIGAPERFFATLRAAGVTPATRALPDHYAFATNPFVDDHFDAILITEKDAVKLGTSWRDARIWV
VPVEAALDPRLIALVVEKLRGRTSA

Specific function: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) [H]

COG id: COG1663

COG function: function code M; Tetraacyldisaccharide-1-P 4'-kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxK family [H]

Homologues:

Organism=Escherichia coli, GI1787144, Length=330, Percent_Identity=43.3333333333333, Blast_Score=202, Evalue=4e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003758 [H]

Pfam domain/function: PF02606 LpxK [H]

EC number: =2.7.1.130 [H]

Molecular weight: Translated: 37029; Mature: 36898

Theoretical pI: Translated: 11.07; Mature: 11.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVMSARPGLLARAEARLTREWQRRGALAWALTPFACAFGAIAALRRAAYARGWKARVD
CCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEC
CGVPVVVVGNVTVGGTGKTPTVIALVDALRAAGFTPGVVSRGYGAKIVAPTAVTPASAPQ
CCCCEEEEECEEECCCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCEEEECCCCCCCCCCH
QAGDEPLLIARRTLAPVWVCPDRVAAVRALKAAHPEVDVVVSDDGLQHYRLARAVEIVVF
HCCCCCEEEEHHHCCCEEECCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHEEEEEEE
DHRLGGNGFLLPAGPLREPLSRRRDATLVNDPYSRALPPWPDTFALSLAPGDAWHLARPS
EEEECCCEEEECCCHHHHHHHHHCCCCEECCCHHHCCCCCCCCEEEEECCCCCEECCCCC
RRKPLAQFAGERVLAAAGIGAPERFFATLRAAGVTPATRALPDHYAFATNPFVDDHFDAI
CCCCHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHCCCCCCEECCCCCCCCCCCEE
LITEKDAVKLGTSWRDARIWVVPVEAALDPRLIALVVEKLRGRTSA
EEECCCCEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SRVMSARPGLLARAEARLTREWQRRGALAWALTPFACAFGAIAALRRAAYARGWKARVD
CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEC
CGVPVVVVGNVTVGGTGKTPTVIALVDALRAAGFTPGVVSRGYGAKIVAPTAVTPASAPQ
CCCCEEEEECEEECCCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCEEEECCCCCCCCCCH
QAGDEPLLIARRTLAPVWVCPDRVAAVRALKAAHPEVDVVVSDDGLQHYRLARAVEIVVF
HCCCCCEEEEHHHCCCEEECCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHEEEEEEE
DHRLGGNGFLLPAGPLREPLSRRRDATLVNDPYSRALPPWPDTFALSLAPGDAWHLARPS
EEEECCCEEEECCCHHHHHHHHHCCCCEECCCHHHCCCCCCCCEEEEECCCCCEECCCCC
RRKPLAQFAGERVLAAAGIGAPERFFATLRAAGVTPATRALPDHYAFATNPFVDDHFDAI
CCCCHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHCCCCCCEECCCCCCCCCCCEE
LITEKDAVKLGTSWRDARIWVVPVEAALDPRLIALVVEKLRGRTSA
EEECCCCEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA