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The map label for this gene is hisC-2 [H]

Identifier: 83720949

GI number: 83720949

Start: 3431374

End: 3432444

Strand: Reverse

Name: hisC-2 [H]

Synonym: BTH_I2992

Alternate gene names: 83720949

Gene position: 3432444-3431374 (Counterclockwise)

Preceding gene: 83720216

Following gene: 83721147

Centisome position: 90.11

GC content: 68.44

Gene sequence:

>1071_bases
ATGACTACGCCAGAAGACATCATCCGCCGCGACGTGCTCGCGATGACGAGCTACCCGGTGCCGGACGCGACGGGCTTCGT
GAAGCTCGACGCGATGGAGAACCCTTATTCGCTACCGGCGCCGCTCGCGGCGGAGCTTGGCGAGCGGCTCGCGCACGTTG
CGCTGAACCGCTATCCGGCGCCGCGTCCCGCCGCGCTGATCGACCGGCTGCGCGCCGTGATGGGCGTGCCCGCCGCGTGC
GACGTGCTGCTCGGCAACGGCTCGGACGAGATCATCAGCATCCTCGCGATGGCGTGCGCGAAGCCGGGCGCGAAGGTGCT
CGCGCCGGTGCCGGGCTTCGTGATGTACGAACTGTCGGCGAAATTCGCGCAGCTCGAGTTCGTCGGCGTGCCGCTTCGTG
CGGACCTGACGCTCGACGTCGACGCGATGCTCGCGGCGATCGCCGAGCATCGGCCGGCGCTCGTCTATCTCGCGTATCCG
AACAACCCGACGGGCACGCTGTACCCGGACGAGGACATCGAGCGGATCGTCGCGGCGGCGAACACGAGCCTCGTCGTGAT
CGACGAGGCGTACCAGCCGTTCGCGCAGCGAAGCTGGCTGCCGCGCGCGGCGGAATTCGACAACGTCGTCGTGATGCGCA
CGGTGTCGAAGCTCGGCCTCGCGGGCATCCGCCTCGGCTATCTGGTCGGGCTGCCCGCGTGGCTCACGCAGTTCGACAAG
GTGCGCCCGCCATATAACGTGAACGTGCTGACGCAGGCGGCGGCCGAATTCCTGCTCGAGCGCGTCGACGTGCTCGACGC
GCAGGCCGCGCAACTGCGCGACGCGCGCACGGCGCTCGCGCACGCGATCGGCGCGCTGCCGGGCGCGACCGTGTACCCGA
GCGCGGGCAATTTCCTGCTCGTGCGGGTGCCGGACGCGGCCGCCGTGTTCGACGTGCTCCTGACCGAGCGGGTATTGATC
AAAAACGTGAGTAAAATGCATCCATTGCTCGCCAATTGCGTGCGCGTAACGGTTGGGTCTCCCGAAGAAAACGCGCGCCT
GCTGGCGGCACTGAAACTGGCGCTGCCCTGA

Upstream 100 bases:

>100_bases
ACCCGAGACCGCCCGGCGAGGCGTCTCGCGCGGCGCGACCGATGCGCCGCGCGAGACGCTTCGGCCGGGGCCATGCCGGC
GCCCGCGCGCCGTTGCCATC

Downstream 100 bases:

>100_bases
CGGGCCACCCCGGGGCGCCGCCTTTCTCGTCCCCATTACCTCAGTCAACTCAAGGAATCACCATGCGCGTGGCGGAAGTC
GTTCGCAACACCAGCGAAAC

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 1 [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTTPEDIIRRDVLAMTSYPVPDATGFVKLDAMENPYSLPAPLAAELGERLAHVALNRYPAPRPAALIDRLRAVMGVPAAC
DVLLGNGSDEIISILAMACAKPGAKVLAPVPGFVMYELSAKFAQLEFVGVPLRADLTLDVDAMLAAIAEHRPALVYLAYP
NNPTGTLYPDEDIERIVAAANTSLVVIDEAYQPFAQRSWLPRAAEFDNVVVMRTVSKLGLAGIRLGYLVGLPAWLTQFDK
VRPPYNVNVLTQAAAEFLLERVDVLDAQAAQLRDARTALAHAIGALPGATVYPSAGNFLLVRVPDAAAVFDVLLTERVLI
KNVSKMHPLLANCVRVTVGSPEENARLLAALKLALP

Sequences:

>Translated_356_residues
MTTPEDIIRRDVLAMTSYPVPDATGFVKLDAMENPYSLPAPLAAELGERLAHVALNRYPAPRPAALIDRLRAVMGVPAAC
DVLLGNGSDEIISILAMACAKPGAKVLAPVPGFVMYELSAKFAQLEFVGVPLRADLTLDVDAMLAAIAEHRPALVYLAYP
NNPTGTLYPDEDIERIVAAANTSLVVIDEAYQPFAQRSWLPRAAEFDNVVVMRTVSKLGLAGIRLGYLVGLPAWLTQFDK
VRPPYNVNVLTQAAAEFLLERVDVLDAQAAQLRDARTALAHAIGALPGATVYPSAGNFLLVRVPDAAAVFDVLLTERVLI
KNVSKMHPLLANCVRVTVGSPEENARLLAALKLALP
>Mature_355_residues
TTPEDIIRRDVLAMTSYPVPDATGFVKLDAMENPYSLPAPLAAELGERLAHVALNRYPAPRPAALIDRLRAVMGVPAACD
VLLGNGSDEIISILAMACAKPGAKVLAPVPGFVMYELSAKFAQLEFVGVPLRADLTLDVDAMLAAIAEHRPALVYLAYPN
NPTGTLYPDEDIERIVAAANTSLVVIDEAYQPFAQRSWLPRAAEFDNVVVMRTVSKLGLAGIRLGYLVGLPAWLTQFDKV
RPPYNVNVLTQAAAEFLLERVDVLDAQAAQLRDARTALAHAIGALPGATVYPSAGNFLLVRVPDAAAVFDVLLTERVLIK
NVSKMHPLLANCVRVTVGSPEENARLLAALKLALP

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=363, Percent_Identity=30.8539944903581, Blast_Score=129, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6322075, Length=365, Percent_Identity=28.7671232876712, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 38230; Mature: 38099

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPEDIIRRDVLAMTSYPVPDATGFVKLDAMENPYSLPAPLAAELGERLAHVALNRYPA
CCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
PRPAALIDRLRAVMGVPAACDVLLGNGSDEIISILAMACAKPGAKVLAPVPGFVMYELSA
CCHHHHHHHHHHHHCCCHHHEEEECCCHHHHHHHHHHHHCCCCCCEECCCCCCEEEHHHH
KFAQLEFVGVPLRADLTLDVDAMLAAIAEHRPALVYLAYPNNPTGTLYPDEDIERIVAAA
HHEEEEEEECCEEECCEECHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHC
NTSLVVIDEAYQPFAQRSWLPRAAEFDNVVVMRTVSKLGLAGIRLGYLVGLPAWLTQFDK
CCCEEEEECHHCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VRPPYNVNVLTQAAAEFLLERVDVLDAQAAQLRDARTALAHAIGALPGATVYPSAGNFLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEE
VRVPDAAAVFDVLLTERVLIKNVSKMHPLLANCVRVTVGSPEENARLLAALKLALP
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TTPEDIIRRDVLAMTSYPVPDATGFVKLDAMENPYSLPAPLAAELGERLAHVALNRYPA
CCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
PRPAALIDRLRAVMGVPAACDVLLGNGSDEIISILAMACAKPGAKVLAPVPGFVMYELSA
CCHHHHHHHHHHHHCCCHHHEEEECCCHHHHHHHHHHHHCCCCCCEECCCCCCEEEHHHH
KFAQLEFVGVPLRADLTLDVDAMLAAIAEHRPALVYLAYPNNPTGTLYPDEDIERIVAAA
HHEEEEEEECCEEECCEECHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHC
NTSLVVIDEAYQPFAQRSWLPRAAEFDNVVVMRTVSKLGLAGIRLGYLVGLPAWLTQFDK
CCCEEEEECHHCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VRPPYNVNVLTQAAAEFLLERVDVLDAQAAQLRDARTALAHAIGALPGATVYPSAGNFLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEE
VRVPDAAAVFDVLLTERVLIKNVSKMHPLLANCVRVTVGSPEENARLLAALKLALP
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA