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The map label for this gene is mycA [H]

Identifier: 83720849

GI number: 83720849

Start: 2681946

End: 2686628

Strand: Reverse

Name: mycA [H]

Synonym: BTH_I2366

Alternate gene names: 83720849

Gene position: 2686628-2681946 (Counterclockwise)

Preceding gene: 83721530

Following gene: 83718799

Centisome position: 70.53

GC content: 72.24

Gene sequence:

>4683_bases
GTGACTGTTTACCAAACACCGGTGGATGCAGTGGCGATCGTCGGCGCAAGCTGTCGGCTGCCGGGCGCGGCCACGCTGGA
ACAATTCTGGTCGCTGATCGCCGATGGCCGCGTCGCGATCGAGCGCTTCACCGCCGATGCGGCCCGCCGCGAGGGCGTGC
CGGAGGATGTGCTGGCGCAGCCCGGCTTCGTCGGGGCGGGCGGGCCGCTCGACGGCGTTGATCTGTTCGACGCGGCGTAC
TTCGGCATTGCGCCGTCGCAGGCGGCGGCGATGGACCCGCAGCAGCGGATCTTCCTCGAATGCGTGCACGAGGCGCTCGA
GCGCGCCGGCCACGGCGCGGTGCGCGGCCCTCGCGTCGGGATCTGGGCCGGGTCGGCCACCGTCGATTATCTGGTCGACC
ATGTGCGCGACCGGCTCGATCGCGCGTCGCCGAACCGTTACCTGCAGCAATGGGTGGGCGTCGACAAGGACTATCTCGCG
ACGCAGGTCGCGTACCGGCTGGACTTCGGCGGGCCCGCGGTCACGCTGCAGACCGCCTGTTCGACGTCGCTCGTCGCGGT
GGTCCATGCGCTGCATGGGCTGCTGAGTTTCCAGTGCGACTTCGCGGTGGCGGGCGGCGTCAGCATCGCGCTGCCGCAGC
GGCAAGGGCATGTGTACGAGGAGGGCAGCATCCTGTCCGCCGACGGCGCGTGCCGGCCATTCACGACGGAGAGCGGCGGC
ACCGTCTTCGGCAACGGCGCGGGGGTCGTGGTCCTGCGGCGCCTGGAGGATGCACTCGACGACGGCGACCCGATTCTGGC
GGTGATTCGCGGCGGCGCGATCAACAACGACGGGGCGGCGAAGGTCGGCTTCACCGCGCCGGGCGGCCGGGGGCAGCGCG
AGGTGATCCGTCACGCGCTGGCGTTGAGCGAAGTCGACGGCGCGTCGATCGGCTATGTCGAGACGCACGGCACGGGCACG
GCGATCGGCGACGAGGTCGAACTGGCGGCGCTGACCGAGGCGCTGGGCGATCGACGGCCCGGCGATGCGCGGTGCGCGCT
TGGATCGCTCAAGGCGAACGTCGGGCATCTGAACGCGGCCGCGGGAGCGTGCGGCCTGATCAAGGCCTCGCTGGCGGTGG
CGCACGCGCAGCTTCCGGGGGCGGTGGGCGCCGAACAGGCGATCGGGACGCTGCGCGGCGAATCCGCGTTCTACCTGCCG
ACGAACACGGTGCCGTGGGACGCGCCGCTCCGGCGTGCGGGCGTCAGCTCGTTCGGCATCGGCGGCACCAATGCGCACGT
GATCGTGGAGGCCGCGCCGCCGCGCGCCCCCAGGACGCCGCAAACGGTGCCGCTGCTGTTGCTGTCGGCGCGCGGCACGG
CGCTGCGCGAGCTGTGCGCGAATTATGCGACGTTTCTCGAAGGCGCCCCGGACCTGCGGCTCGAGGACGTGTGCTTGACG
GCGGCCATAGGCCGCCGCCATTGGGAGCAGCGCGCGGCGTTTCGCGCCGAATCCCGCGAGCGGTTGATCGGTTCGCTGCG
GGCATTCGCCGCGGGCGATTCCGATGCCGACGTGATCAGCGCCGAAGTGCCGGCCCGCGTGCCGGAAGTGAGCTTCGCGT
TTGGCGGCGCACGCGATCTCGACGCGGTCCTCGCCCGCGTGCGGGCGTGCGGCGTCGTGCCGGCGAGCGTGTGCGCGACG
GGCGACGGCGTGTTCGCGGCGGCCTTCGCCGCCGGCGCGCTGAGTCTCGACGACGCACGGAACCGTCGCGCGGACAACGT
CGCCGCGCCGGCGCTGCTGTGGATCAGCGCATCGTCGGGCTTGCCCATCGACAGCCCGGAGGCGGTGCGCGACGAACTGG
CGCGCGCGAACGACGCCGCGCACGATGCCGCGGCGGCGCTGGAGGCCGCGGGCGCCGCGCTGGTGCTGGAGTTCGGCGAC
GTGGCATTGGGCGCGGGGGCCGCGGGCGTGGTGTCGCTCGATCCCGCGTCGCCGGAGGCGATCGCCCGCATGTGGACGGC
CGGCGTGGCGCTCGACCTGACGCAGCACTATCGCGACGGCAACCGGGTCGTGCTGCCGACCTATCCGTTCCAGCGCCAGC
GCTTCTGGATCGAGCGCGCGCCACGCTTGGCCGAAGGCGGCGTGTCGCCGTTCCTCGGGCGGCGAACCGACGCGCCCGCG
CTGAATGCGACGCTCTTCGACGCCGACTGGAGCGTGGCGACGCTGCCGTTTCTCCAGGATCACGTCATCTACGGAAAGAT
CGTCGTGTCGGGCGCGGCCCTCGCCGTGATGATCGCCGACGGCGTGCGGGAGCTCACCGGGGCGGATGCTTGCGTGTTGA
GCGACCTGCGCTTTCCGGCGGCACTGGTGATTCCGGCGGGCGCGGCGCGGCGGGTGCAACTGCAACTGGTGCGCGACGGC
GACGGTTTCGAGGCGGCCGTGCTCACGCCCGAGCCCTTCGAAACCCATGCGACGGCACGTGCCGAAGCGGGCGCGGATCA
AGACGTCGCGCCATCGGCGCAGGTGCGCGGCGAAGCGATCTCCACCGACTTGCTGGATACCTGGCTGCGCGCTCGCAGCG
TCGTCATGGGGCCGACGTTCCGCCGGCTCTCGGAGATCGTCGTGAGCGGCAGCGAGGCTGCCTGCGCGATGCGTGCCGAT
CCCGGCGACGCGGGCTGGCCGCTGCACCCCGGCATTCTCGACTCGGCGCTGCAACTGGTCGCGGCCGCCGCGCGGCCCGA
TGGAAACGACGCGTTCGTGCCGACTCGCATCGCACGGTTGACGATCCGCGGGCGCGCCGGCGCGCAGATGCGCTGCTATG
CGGCCGCCGACCGCGGTTACGCGAGCGTGTTCGACGGTAACGGCGCGCTCGTCGAGCTGACGGGCCTCGAATCGCGCGAG
GTCAGCCGCAACGAGCTGCTGCGAATCGAGCCGCTGCGCGACGGCTACGCGGTTCAATGGCGATGCGTGACGGACGGTGC
GCCATTCGCGTTGCCGGAGCCGATCGTCGTCGTGCGCGATGCGGGCGAGGTCGCATCGGGGCTCGCGTCGATCTTGCGCG
ACGAGGCCAAAGAGACGCTCGTCGTCGCGACGCCGGACGAGATCCCGTTCGAGCGGGCCGGCCTGATCATCGATTGCCGC
GGCATCGACGCGCGCTCGGCCGCGCCGGCCCCGGCGCTCTACGAGGGCGCCCTTGCGCTGTTCGCGGCGGCCGCCCGGCG
CGACGAGCCCTGCCGGATCGCCGTCGTCCTGGCGCCGCAGGCACCGGCGTCGGCACCGTTGCAGGCGCTCGCGCGAGCGG
CCGCGATGGAAACCCCGCACCTGCGCACGCTCGCGCTGCATGCGGGCGACGCCCACGCGATTCGCCGCGGCCTCGACTGC
TTCGATCGGGAAACCGAGGTCTCGGTCCGCGGCACGGAGGTCACGGCGCCGCGCCTCGACGAGCGCGCGCTGCCCCGGCG
CGCCGAATATGCGCCGGCGGGCGAGGGAACCTGGCTGATCACGGGCGGCCTGGGCGATCTCGGGCTGCAAGTCGCGGGCT
GGCTCGCGGCACTCGGCGTGCGCTCGCTGATGCTCGTCGGCCGCCGGCCACCCGGCGACGCGGCCGAGGAGACGCTCGCC
GCATTGCGGCGGGACGGCGTCGATGTGCAGGTGAGGCAGGCCGACCTGTCGCGGGAAGCGGACGTCGATGCGCTGCTGCA
CGAAATCGGCGCGACGATGCCGCCGCTGCGCGGAATCTGCCATCTCGCGGGCGTCGTCGAAGACCGGCTGGTGAGCGACG
TCACGCCGGCGTCGCTCGCCGCGACCTTTGCCGGAAAGGCTCAGGGCGCGTGGCTGCTGCACGAGCGCACGCGCGGCCAT
GCGCTCGAACACTTCGTGCTCTTCTCGTCCGCGGCCGCCGCGTTCGGCGCGCCGGGGCAGGCGAGCTACGCGATGGCGAA
TGCGTACCTGGACGCGCTGGCCGCGCATCGCCGCTCGCAGGGCCTGCCCGCGCTGTCCCTCGCATGGGGGCCATGGCAGG
ACGTCGGCATGCTGGCCCGCACGGCGGCGAGCGCCAAGCGCCGGCTGGCGCAACTGGGCATCGGTCAGATCGAAACCGAA
TGCGGACGCGCGACGTTCGAGATCGCGCTGGCCGCCGATTTGCCGCCGCATGTCGTGCTGTTGCCGATCGACTGGCAGCG
GCTCATCGATCAATGGCCGCCGCACGTTCCCGCAAGCCGCTTCGACGGCATCGCCACCGCGCGGCCCGGCGCCGGGCTCA
CTTCGTCGGTCAGCGAATTGCTGGCGCTTCCTGCGGCCGAGCGCCGGCATCGATTGTTCCAACTGCTCGCCGAGGATGCG
GCGGCCGTGACCGGCACGAGTCTCGCCGCGCTCGATCCGGAACGCTCGCTGTTCGACTACGACCTGGATTCCCTGCTGAT
CACCGACCTGCGCGTGCGGCTCGAAAAGCGCTTCGGCCGCACGATCTCGACCACGGTCATCTTTTCGAACCCGACGATCG
CCGCGCTTGCCGACTACTTGGCTCGGACGATCTTCGGCGCGGCGCTCGACGCTCCCGCCGCCGCAGCAGCAGACACGGAT
ACGGCGGCGCCCGCGCCCGGCGACGCGCAACCGCAGGCGCCGGCGGAGCGGCTGTCGCAAGAGGAGATCGTCGAACTGCT
GTCCGCAAAGTTGGACGAGCTTCGGGGGGCGGACTCGCGATGA

Upstream 100 bases:

>100_bases
CCTCGCGTTCCGCCGCGAGCGGCGCAGACACGCTCAACGCGAAGGACGTCGCCGGCGTGCGCGCCTACAGACAGCGCGCA
CGCGCACGCAAGGAGGCTAT

Downstream 100 bases:

>100_bases
ATACGATCGACCCCACTGCGCTGATGCAGGACGCGCTGCTCGAAATCGAGCGCCTGCAACACAAACTCGGCAAGTTCGAG
CAGCAACGGCATGAGCCAAT

Product: polyketide synthase

Products: L-tryptophan [Cytoplasm]; L-tyrosine [Cytoplasm]; Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: Glutamate-1-semialdehyde aminotransferase; GSA-AT; ATP-dependent asparagine adenylase 1; AsnA 1; Asparagine activase 1 [H]

Number of amino acids: Translated: 1560; Mature: 1559

Protein sequence:

>1560_residues
MTVYQTPVDAVAIVGASCRLPGAATLEQFWSLIADGRVAIERFTADAARREGVPEDVLAQPGFVGAGGPLDGVDLFDAAY
FGIAPSQAAAMDPQQRIFLECVHEALERAGHGAVRGPRVGIWAGSATVDYLVDHVRDRLDRASPNRYLQQWVGVDKDYLA
TQVAYRLDFGGPAVTLQTACSTSLVAVVHALHGLLSFQCDFAVAGGVSIALPQRQGHVYEEGSILSADGACRPFTTESGG
TVFGNGAGVVVLRRLEDALDDGDPILAVIRGGAINNDGAAKVGFTAPGGRGQREVIRHALALSEVDGASIGYVETHGTGT
AIGDEVELAALTEALGDRRPGDARCALGSLKANVGHLNAAAGACGLIKASLAVAHAQLPGAVGAEQAIGTLRGESAFYLP
TNTVPWDAPLRRAGVSSFGIGGTNAHVIVEAAPPRAPRTPQTVPLLLLSARGTALRELCANYATFLEGAPDLRLEDVCLT
AAIGRRHWEQRAAFRAESRERLIGSLRAFAAGDSDADVISAEVPARVPEVSFAFGGARDLDAVLARVRACGVVPASVCAT
GDGVFAAAFAAGALSLDDARNRRADNVAAPALLWISASSGLPIDSPEAVRDELARANDAAHDAAAALEAAGAALVLEFGD
VALGAGAAGVVSLDPASPEAIARMWTAGVALDLTQHYRDGNRVVLPTYPFQRQRFWIERAPRLAEGGVSPFLGRRTDAPA
LNATLFDADWSVATLPFLQDHVIYGKIVVSGAALAVMIADGVRELTGADACVLSDLRFPAALVIPAGAARRVQLQLVRDG
DGFEAAVLTPEPFETHATARAEAGADQDVAPSAQVRGEAISTDLLDTWLRARSVVMGPTFRRLSEIVVSGSEAACAMRAD
PGDAGWPLHPGILDSALQLVAAAARPDGNDAFVPTRIARLTIRGRAGAQMRCYAAADRGYASVFDGNGALVELTGLESRE
VSRNELLRIEPLRDGYAVQWRCVTDGAPFALPEPIVVVRDAGEVASGLASILRDEAKETLVVATPDEIPFERAGLIIDCR
GIDARSAAPAPALYEGALALFAAAARRDEPCRIAVVLAPQAPASAPLQALARAAAMETPHLRTLALHAGDAHAIRRGLDC
FDRETEVSVRGTEVTAPRLDERALPRRAEYAPAGEGTWLITGGLGDLGLQVAGWLAALGVRSLMLVGRRPPGDAAEETLA
ALRRDGVDVQVRQADLSREADVDALLHEIGATMPPLRGICHLAGVVEDRLVSDVTPASLAATFAGKAQGAWLLHERTRGH
ALEHFVLFSSAAAAFGAPGQASYAMANAYLDALAAHRRSQGLPALSLAWGPWQDVGMLARTAASAKRRLAQLGIGQIETE
CGRATFEIALAADLPPHVVLLPIDWQRLIDQWPPHVPASRFDGIATARPGAGLTSSVSELLALPAAERRHRLFQLLAEDA
AAVTGTSLAALDPERSLFDYDLDSLLITDLRVRLEKRFGRTISTTVIFSNPTIAALADYLARTIFGAALDAPAAAAADTD
TAAPAPGDAQPQAPAERLSQEEIVELLSAKLDELRGADSR

Sequences:

>Translated_1560_residues
MTVYQTPVDAVAIVGASCRLPGAATLEQFWSLIADGRVAIERFTADAARREGVPEDVLAQPGFVGAGGPLDGVDLFDAAY
FGIAPSQAAAMDPQQRIFLECVHEALERAGHGAVRGPRVGIWAGSATVDYLVDHVRDRLDRASPNRYLQQWVGVDKDYLA
TQVAYRLDFGGPAVTLQTACSTSLVAVVHALHGLLSFQCDFAVAGGVSIALPQRQGHVYEEGSILSADGACRPFTTESGG
TVFGNGAGVVVLRRLEDALDDGDPILAVIRGGAINNDGAAKVGFTAPGGRGQREVIRHALALSEVDGASIGYVETHGTGT
AIGDEVELAALTEALGDRRPGDARCALGSLKANVGHLNAAAGACGLIKASLAVAHAQLPGAVGAEQAIGTLRGESAFYLP
TNTVPWDAPLRRAGVSSFGIGGTNAHVIVEAAPPRAPRTPQTVPLLLLSARGTALRELCANYATFLEGAPDLRLEDVCLT
AAIGRRHWEQRAAFRAESRERLIGSLRAFAAGDSDADVISAEVPARVPEVSFAFGGARDLDAVLARVRACGVVPASVCAT
GDGVFAAAFAAGALSLDDARNRRADNVAAPALLWISASSGLPIDSPEAVRDELARANDAAHDAAAALEAAGAALVLEFGD
VALGAGAAGVVSLDPASPEAIARMWTAGVALDLTQHYRDGNRVVLPTYPFQRQRFWIERAPRLAEGGVSPFLGRRTDAPA
LNATLFDADWSVATLPFLQDHVIYGKIVVSGAALAVMIADGVRELTGADACVLSDLRFPAALVIPAGAARRVQLQLVRDG
DGFEAAVLTPEPFETHATARAEAGADQDVAPSAQVRGEAISTDLLDTWLRARSVVMGPTFRRLSEIVVSGSEAACAMRAD
PGDAGWPLHPGILDSALQLVAAAARPDGNDAFVPTRIARLTIRGRAGAQMRCYAAADRGYASVFDGNGALVELTGLESRE
VSRNELLRIEPLRDGYAVQWRCVTDGAPFALPEPIVVVRDAGEVASGLASILRDEAKETLVVATPDEIPFERAGLIIDCR
GIDARSAAPAPALYEGALALFAAAARRDEPCRIAVVLAPQAPASAPLQALARAAAMETPHLRTLALHAGDAHAIRRGLDC
FDRETEVSVRGTEVTAPRLDERALPRRAEYAPAGEGTWLITGGLGDLGLQVAGWLAALGVRSLMLVGRRPPGDAAEETLA
ALRRDGVDVQVRQADLSREADVDALLHEIGATMPPLRGICHLAGVVEDRLVSDVTPASLAATFAGKAQGAWLLHERTRGH
ALEHFVLFSSAAAAFGAPGQASYAMANAYLDALAAHRRSQGLPALSLAWGPWQDVGMLARTAASAKRRLAQLGIGQIETE
CGRATFEIALAADLPPHVVLLPIDWQRLIDQWPPHVPASRFDGIATARPGAGLTSSVSELLALPAAERRHRLFQLLAEDA
AAVTGTSLAALDPERSLFDYDLDSLLITDLRVRLEKRFGRTISTTVIFSNPTIAALADYLARTIFGAALDAPAAAAADTD
TAAPAPGDAQPQAPAERLSQEEIVELLSAKLDELRGADSR
>Mature_1559_residues
TVYQTPVDAVAIVGASCRLPGAATLEQFWSLIADGRVAIERFTADAARREGVPEDVLAQPGFVGAGGPLDGVDLFDAAYF
GIAPSQAAAMDPQQRIFLECVHEALERAGHGAVRGPRVGIWAGSATVDYLVDHVRDRLDRASPNRYLQQWVGVDKDYLAT
QVAYRLDFGGPAVTLQTACSTSLVAVVHALHGLLSFQCDFAVAGGVSIALPQRQGHVYEEGSILSADGACRPFTTESGGT
VFGNGAGVVVLRRLEDALDDGDPILAVIRGGAINNDGAAKVGFTAPGGRGQREVIRHALALSEVDGASIGYVETHGTGTA
IGDEVELAALTEALGDRRPGDARCALGSLKANVGHLNAAAGACGLIKASLAVAHAQLPGAVGAEQAIGTLRGESAFYLPT
NTVPWDAPLRRAGVSSFGIGGTNAHVIVEAAPPRAPRTPQTVPLLLLSARGTALRELCANYATFLEGAPDLRLEDVCLTA
AIGRRHWEQRAAFRAESRERLIGSLRAFAAGDSDADVISAEVPARVPEVSFAFGGARDLDAVLARVRACGVVPASVCATG
DGVFAAAFAAGALSLDDARNRRADNVAAPALLWISASSGLPIDSPEAVRDELARANDAAHDAAAALEAAGAALVLEFGDV
ALGAGAAGVVSLDPASPEAIARMWTAGVALDLTQHYRDGNRVVLPTYPFQRQRFWIERAPRLAEGGVSPFLGRRTDAPAL
NATLFDADWSVATLPFLQDHVIYGKIVVSGAALAVMIADGVRELTGADACVLSDLRFPAALVIPAGAARRVQLQLVRDGD
GFEAAVLTPEPFETHATARAEAGADQDVAPSAQVRGEAISTDLLDTWLRARSVVMGPTFRRLSEIVVSGSEAACAMRADP
GDAGWPLHPGILDSALQLVAAAARPDGNDAFVPTRIARLTIRGRAGAQMRCYAAADRGYASVFDGNGALVELTGLESREV
SRNELLRIEPLRDGYAVQWRCVTDGAPFALPEPIVVVRDAGEVASGLASILRDEAKETLVVATPDEIPFERAGLIIDCRG
IDARSAAPAPALYEGALALFAAAARRDEPCRIAVVLAPQAPASAPLQALARAAAMETPHLRTLALHAGDAHAIRRGLDCF
DRETEVSVRGTEVTAPRLDERALPRRAEYAPAGEGTWLITGGLGDLGLQVAGWLAALGVRSLMLVGRRPPGDAAEETLAA
LRRDGVDVQVRQADLSREADVDALLHEIGATMPPLRGICHLAGVVEDRLVSDVTPASLAATFAGKAQGAWLLHERTRGHA
LEHFVLFSSAAAAFGAPGQASYAMANAYLDALAAHRRSQGLPALSLAWGPWQDVGMLARTAASAKRRLAQLGIGQIETEC
GRATFEIALAADLPPHVVLLPIDWQRLIDQWPPHVPASRFDGIATARPGAGLTSSVSELLALPAAERRHRLFQLLAEDAA
AVTGTSLAALDPERSLFDYDLDSLLITDLRVRLEKRFGRTISTTVIFSNPTIAALADYLARTIFGAALDAPAAAAADTDT
AAPAPGDAQPQAPAERLSQEEIVELLSAKLDELRGADSR

Specific function: This protein is a multifunctional enzyme, able to activate a long chain fatty acid and link it with the amino acid Asn as part of the synthesis of mycosubtilin. The activation sites consist of individual domains [H]

COG id: COG3321

COG function: function code Q; Polyketide synthase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=437, Percent_Identity=30.2059496567506, Blast_Score=187, Evalue=1e-46,
Organism=Homo sapiens, GI8923559, Length=278, Percent_Identity=30.2158273381295, Blast_Score=91, Evalue=9e-18,
Organism=Escherichia coli, GI1788663, Length=265, Percent_Identity=31.3207547169811, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1787337, Length=267, Percent_Identity=28.8389513108614, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17550940, Length=424, Percent_Identity=31.3679245283019, Blast_Score=189, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI212642053, Length=469, Percent_Identity=28.3582089552239, Blast_Score=177, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI71983541, Length=277, Percent_Identity=28.5198555956679, Blast_Score=79, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71983535, Length=266, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320904, Length=271, Percent_Identity=25.4612546125461, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI221330659, Length=454, Percent_Identity=30.8370044052863, Blast_Score=196, Evalue=1e-49,
Organism=Drosophila melanogaster, GI19920632, Length=454, Percent_Identity=30.8370044052863, Blast_Score=195, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24581345, Length=458, Percent_Identity=29.2576419213974, Blast_Score=182, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24644341, Length=276, Percent_Identity=28.2608695652174, Blast_Score=79, Evalue=3e-14,

Paralogues:

None

Copy number: 24024 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 30,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR005814
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00202 Aminotran_3; PF00501 AMP-binding; PF00668 Condensation; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF00550 PP-binding [H]

EC number: 2.3.1.41 [C]

Molecular weight: Translated: 163396; Mature: 163265

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50075 ACP_DOMAIN ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVYQTPVDAVAIVGASCRLPGAATLEQFWSLIADGRVAIERFTADAARREGVPEDVLAQ
CCEECCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHCC
PGFVGAGGPLDGVDLFDAAYFGIAPSQAAAMDPQQRIFLECVHEALERAGHGAVRGPRVG
CCCCCCCCCCCCHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEE
IWAGSATVDYLVDHVRDRLDRASPNRYLQQWVGVDKDYLATQVAYRLDFGGPAVTLQTAC
EEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHEEECCCCEEEEHHHH
STSLVAVVHALHGLLSFQCDFAVAGGVSIALPQRQGHVYEEGSILSADGACRPFTTESGG
HHHHHHHHHHHHHHHHHCCCEEEECCEEEEECCCCCCEECCCCEEECCCCCCCCCCCCCC
TVFGNGAGVVVLRRLEDALDDGDPILAVIRGGAINNDGAAKVGFTAPGGRGQREVIRHAL
EEEECCCCEEEEHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHH
ALSEVDGASIGYVETHGTGTAIGDEVELAALTEALGDRRPGDARCALGSLKANVGHLNAA
HHHCCCCCEECEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHH
AGACGLIKASLAVAHAQLPGAVGAEQAIGTLRGESAFYLPTNTVPWDAPLRRAGVSSFGI
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCHHHHCCCCCCCC
GGTNAHVIVEAAPPRAPRTPQTVPLLLLSARGTALRELCANYATFLEGAPDLRLEDVCLT
CCCCCEEEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AAIGRRHWEQRAAFRAESRERLIGSLRAFAAGDSDADVISAEVPARVPEVSFAFGGARDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEECCCCCCH
DAVLARVRACGVVPASVCATGDGVFAAAFAAGALSLDDARNRRADNVAAPALLWISASSG
HHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEEEECCCC
LPIDSPEAVRDELARANDAAHDAAAALEAAGAALVLEFGDVALGAGAAGVVSLDPASPEA
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCEEECCCCCCEEEECCCCHHH
IARMWTAGVALDLTQHYRDGNRVVLPTYPFQRQRFWIERAPRLAEGGVSPFLGRRTDAPA
HHHHHHHHHHEEEHHHHCCCCEEEECCCCCHHHHHHHHHCCCHHHCCCCCCCCCCCCCCC
LNATLFDADWSVATLPFLQDHVIYGKIVVSGAALAVMIADGVRELTGADACVLSDLRFPA
CCEEEEECCCCEEECCHHHCCCEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHCCCCE
ALVIPAGAARRVQLQLVRDGDGFEAAVLTPEPFETHATARAEAGADQDVAPSAQVRGEAI
EEEECCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCHHHCCCHH
STDLLDTWLRARSVVMGPTFRRLSEIVVSGSEAACAMRADPGDAGWPLHPGILDSALQLV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
AAAARPDGNDAFVPTRIARLTIRGRAGAQMRCYAAADRGYASVFDGNGALVELTGLESRE
HHHCCCCCCCCCCCEEEEEEEEECCCCCCEEEEEECCCCCEEEECCCCCEEEEECCCCCC
VSRNELLRIEPLRDGYAVQWRCVTDGAPFALPEPIVVVRDAGEVASGLASILRDEAKETL
CCHHCCEEEEECCCCCEEEEEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCEE
VVATPDEIPFERAGLIIDCRGIDARSAAPAPALYEGALALFAAAARRDEPCRIAVVLAPQ
EEECCCCCCHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCC
APASAPLQALARAAAMETPHLRTLALHAGDAHAIRRGLDCFDRETEVSVRGTEVTAPRLD
CCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCEECCCCCC
ERALPRRAEYAPAGEGTWLITGGLGDLGLQVAGWLAALGVRSLMLVGRRPPGDAAEETLA
HHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ALRRDGVDVQVRQADLSREADVDALLHEIGATMPPLRGICHLAGVVEDRLVSDVTPASLA
HHHHCCCCEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
ATFAGKAQGAWLLHERTRGHALEHFVLFSSAAAAFGAPGQASYAMANAYLDALAAHRRSQ
HHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
GLPALSLAWGPWQDVGMLARTAASAKRRLAQLGIGQIETECGRATFEIALAADLPPHVVL
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEEEEECCCCCCEEE
LPIDWQRLIDQWPPHVPASRFDGIATARPGAGLTSSVSELLALPAAERRHRLFQLLAEDA
EECCHHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
AAVTGTSLAALDPERSLFDYDLDSLLITDLRVRLEKRFGRTISTTVIFSNPTIAALADYL
HHHCCCEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHH
ARTIFGAALDAPAAAAADTDTAAPAPGDAQPQAPAERLSQEEIVELLSAKLDELRGADSR
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TVYQTPVDAVAIVGASCRLPGAATLEQFWSLIADGRVAIERFTADAARREGVPEDVLAQ
CEECCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHCC
PGFVGAGGPLDGVDLFDAAYFGIAPSQAAAMDPQQRIFLECVHEALERAGHGAVRGPRVG
CCCCCCCCCCCCHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEE
IWAGSATVDYLVDHVRDRLDRASPNRYLQQWVGVDKDYLATQVAYRLDFGGPAVTLQTAC
EEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHEEECCCCEEEEHHHH
STSLVAVVHALHGLLSFQCDFAVAGGVSIALPQRQGHVYEEGSILSADGACRPFTTESGG
HHHHHHHHHHHHHHHHHCCCEEEECCEEEEECCCCCCEECCCCEEECCCCCCCCCCCCCC
TVFGNGAGVVVLRRLEDALDDGDPILAVIRGGAINNDGAAKVGFTAPGGRGQREVIRHAL
EEEECCCCEEEEHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHH
ALSEVDGASIGYVETHGTGTAIGDEVELAALTEALGDRRPGDARCALGSLKANVGHLNAA
HHHCCCCCEECEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHH
AGACGLIKASLAVAHAQLPGAVGAEQAIGTLRGESAFYLPTNTVPWDAPLRRAGVSSFGI
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCHHHHCCCCCCCC
GGTNAHVIVEAAPPRAPRTPQTVPLLLLSARGTALRELCANYATFLEGAPDLRLEDVCLT
CCCCCEEEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AAIGRRHWEQRAAFRAESRERLIGSLRAFAAGDSDADVISAEVPARVPEVSFAFGGARDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEECCCCCCH
DAVLARVRACGVVPASVCATGDGVFAAAFAAGALSLDDARNRRADNVAAPALLWISASSG
HHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEEEECCCC
LPIDSPEAVRDELARANDAAHDAAAALEAAGAALVLEFGDVALGAGAAGVVSLDPASPEA
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCEEECCCCCCEEEECCCCHHH
IARMWTAGVALDLTQHYRDGNRVVLPTYPFQRQRFWIERAPRLAEGGVSPFLGRRTDAPA
HHHHHHHHHHEEEHHHHCCCCEEEECCCCCHHHHHHHHHCCCHHHCCCCCCCCCCCCCCC
LNATLFDADWSVATLPFLQDHVIYGKIVVSGAALAVMIADGVRELTGADACVLSDLRFPA
CCEEEEECCCCEEECCHHHCCCEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHCCCCE
ALVIPAGAARRVQLQLVRDGDGFEAAVLTPEPFETHATARAEAGADQDVAPSAQVRGEAI
EEEECCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCHHHCCCHH
STDLLDTWLRARSVVMGPTFRRLSEIVVSGSEAACAMRADPGDAGWPLHPGILDSALQLV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
AAAARPDGNDAFVPTRIARLTIRGRAGAQMRCYAAADRGYASVFDGNGALVELTGLESRE
HHHCCCCCCCCCCCEEEEEEEEECCCCCCEEEEEECCCCCEEEECCCCCEEEEECCCCCC
VSRNELLRIEPLRDGYAVQWRCVTDGAPFALPEPIVVVRDAGEVASGLASILRDEAKETL
CCHHCCEEEEECCCCCEEEEEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCEE
VVATPDEIPFERAGLIIDCRGIDARSAAPAPALYEGALALFAAAARRDEPCRIAVVLAPQ
EEECCCCCCHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCC
APASAPLQALARAAAMETPHLRTLALHAGDAHAIRRGLDCFDRETEVSVRGTEVTAPRLD
CCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCEECCCCCC
ERALPRRAEYAPAGEGTWLITGGLGDLGLQVAGWLAALGVRSLMLVGRRPPGDAAEETLA
HHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ALRRDGVDVQVRQADLSREADVDALLHEIGATMPPLRGICHLAGVVEDRLVSDVTPASLA
HHHHCCCCEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
ATFAGKAQGAWLLHERTRGHALEHFVLFSSAAAAFGAPGQASYAMANAYLDALAAHRRSQ
HHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
GLPALSLAWGPWQDVGMLARTAASAKRRLAQLGIGQIETECGRATFEIALAADLPPHVVL
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEEEEECCCCCCEEE
LPIDWQRLIDQWPPHVPASRFDGIATARPGAGLTSSVSELLALPAAERRHRLFQLLAEDA
EECCHHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
AAVTGTSLAALDPERSLFDYDLDSLLITDLRVRLEKRFGRTISTTVIFSNPTIAALADYL
HHHCCCEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHH
ARTIFGAALDAPAAAAADTDTAAPAPGDAQPQAPAERLSQEEIVELLSAKLDELRGADSR
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: 2-Mercaptoethanol; DTT; EDTA [C]

Metal ions: Phosphate [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} [C]

Substrates: L-tryptophan [Periplasm]; L-tyrosine [Periplasm]; Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: acyl-ACP + malonyl-ACP = beta-keto-enoyl-ACP + [acyl carrier protein] + CO2 acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 malonyl-ACP = acetyl-ACP + CO2

General reaction: Acyl group transfer [C]

Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl -ACP-decarboxyl ation, [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10557314 [H]