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The map label for this gene is pilQ [H]

Identifier: 83720708

GI number: 83720708

Start: 3467494

End: 3469224

Strand: Reverse

Name: pilQ [H]

Synonym: BTH_I3025

Alternate gene names: 83720708

Gene position: 3469224-3467494 (Counterclockwise)

Preceding gene: 83721075

Following gene: 83719637

Centisome position: 91.07

GC content: 70.54

Gene sequence:

>1731_bases
ATGATGCGCGGATTCGTTTGGGTCATGCTGGGATGCGCGATCGGGGCGGCGGGCGTGGCGGTCGCATCGCCGCCGCCGTT
GCCCGCGGGTGTGCCGGCCGGTTGGGCGGTGTCGGCCTCGGTCGGAGCGGTGGGGCGCGCGCCGTTGCCCGACGCGGCCG
CGTCGAGGTGGCGAATCGATTCCGAGCGTGACGCGGTTGCCGAAGCGCCGACGCCGGATGCGGGCGGCGGCGCGCCGGCC
GATGAGTTCGCCGGCGACGCCGCGCCCGAAAGCACGTCGGCAGCCAATTCGGTCGAGCCATCCGGTTCGGCGCCGGCCGC
CACCGGGCTGCCGAGCCGGGCGGCGTCGGTGCAAGCGGAGGATGCGGCGCTGGATGCGGTGCTGGAGGGGCCGCCCGTGC
CACTCTCGCCGGAGCAACGCATGAGCGACGAGCATCCTGCGTTGCCGTCGGATACTGAAGTCGCATCGGCCGGCGCCAAC
GCCAACGCCAACGCCAATGCCGAGACCGCGGCCGAATCCGACGACAACCGCGCGATCTCGCTCAATCTGCAGCAGGCGAG
CCTCGCAGCGGTCTTCGATGCATTCGCGCGCTTCACCGGCCTCAATATAGTGGTCAGCGAGCGGGTGCGCGGCACGGTGT
CGTTGCGTCTGAACAATGTCCGCTGGCGCAGTGCGTTCGACGCGCTGCTGGACGCCCACGGCCTCGCGATGGCGCGGCGC
GGCAGCGTGATATGGGTCGCGCCTGTCGCGGAACTCGCCGAGCGCGAGCGCCGGCGTTTCGATGCGCACGCGCGCGCCGC
TCAACTCGAACCGCTCGCGAGCCGCAGCTTCGTGCTCCGCTACGCGCGTGCGGCCGACGTGCAGCGTCTGCTCTCGGGCT
CGGCCGCCCAGCGGATACTGTCGAAGCGCGGCTCGGTGCTCGCCGATCCTCGGACGAATCTGCTGTTCGTCACGGATCTG
TCCGGGCGTCTCGCGCAGATCGCCGATCTCATCGGCAAGCTCGACACGCCATCGCGGCAGGTGTTGATCGAGGCGCGGAT
CGTCGAGGGCGATCGCGGGTTCTCACGCAATCTCGGCGCGCGTCTCGCGCTGCGTGCGCCGGATGCGGGCGACCGCGCGG
CGGGCGTCGTCGCGGGCCGTAACGGCACGTTGGCCGACCTCACCGCCAGGCCGATCAGCGGCTTCGACGCGGCGACAGCC
GGCCTCACGCTGTTCGCCGCGCGCGCGAGCCGCTTGCTCGACATCGAATTGAGCGCGCTCGAGGCGCAGGGCCGGGGCCA
GATCGTGTCGAGCCCGCGCGTCGTGACGGCGGACCGGACCAAGGCCGTCGTCGAGCAGGGCGCAGAACTGCCGTATCAGG
CGAAGGTAGGCAACGGCGTGTCGGGCGTCCAGTTCCGGCGCGCGACCTTGAAGCTCGAAGTCGAGCCGCAGATCACGCCC
GACGGGCGCGTGATCCTCGATCTCGACGTCGCGAAGGACAGCGTCGGCGAGGAAACCGCATCCGGCCCCGCGATCCATAC
GAAGCACGTGCAGACGCGCGTCGAGGTCGAAAACGGCGGAACGGTGTCGATCGGCGGGATTTTCGAGAGCGACGACCGCG
ACGATGTGACTCGGGTGCCGCTCTTGGGCAAAATACCGGTGTTGGGCGCGCTTTTCAGGCATCGCGCACAGCGTGCGCAG
CGCAGCGAGCTCGTCGTCTACATCACGCCGACCGTCGTGATCGGGCCCTGA

Upstream 100 bases:

>100_bases
TGGTCGACGGCGCGCGTGTCGCGCGAATCCAGGCGGGCGGCGTGACGCTCGCGACACATGGCGGCGGACGGCGCGTAATG
ACCGTGAGCGGAGCGGCAGG

Downstream 100 bases:

>100_bases
ACCCCGTGGGAGCCAGGCTCGACAAGGCGGGCGCTTTGCCAGTAAGCTGCGCGACACACTCATTGAAGCAGAGGAAGCCG
TTGCAAGCGCGGGACCCACA

Product: type II/III secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MMRGFVWVMLGCAIGAAGVAVASPPPLPAGVPAGWAVSASVGAVGRAPLPDAAASRWRIDSERDAVAEAPTPDAGGGAPA
DEFAGDAAPESTSAANSVEPSGSAPAATGLPSRAASVQAEDAALDAVLEGPPVPLSPEQRMSDEHPALPSDTEVASAGAN
ANANANAETAAESDDNRAISLNLQQASLAAVFDAFARFTGLNIVVSERVRGTVSLRLNNVRWRSAFDALLDAHGLAMARR
GSVIWVAPVAELAERERRRFDAHARAAQLEPLASRSFVLRYARAADVQRLLSGSAAQRILSKRGSVLADPRTNLLFVTDL
SGRLAQIADLIGKLDTPSRQVLIEARIVEGDRGFSRNLGARLALRAPDAGDRAAGVVAGRNGTLADLTARPISGFDAATA
GLTLFAARASRLLDIELSALEAQGRGQIVSSPRVVTADRTKAVVEQGAELPYQAKVGNGVSGVQFRRATLKLEVEPQITP
DGRVILDLDVAKDSVGEETASGPAIHTKHVQTRVEVENGGTVSIGGIFESDDRDDVTRVPLLGKIPVLGALFRHRAQRAQ
RSELVVYITPTVVIGP

Sequences:

>Translated_576_residues
MMRGFVWVMLGCAIGAAGVAVASPPPLPAGVPAGWAVSASVGAVGRAPLPDAAASRWRIDSERDAVAEAPTPDAGGGAPA
DEFAGDAAPESTSAANSVEPSGSAPAATGLPSRAASVQAEDAALDAVLEGPPVPLSPEQRMSDEHPALPSDTEVASAGAN
ANANANAETAAESDDNRAISLNLQQASLAAVFDAFARFTGLNIVVSERVRGTVSLRLNNVRWRSAFDALLDAHGLAMARR
GSVIWVAPVAELAERERRRFDAHARAAQLEPLASRSFVLRYARAADVQRLLSGSAAQRILSKRGSVLADPRTNLLFVTDL
SGRLAQIADLIGKLDTPSRQVLIEARIVEGDRGFSRNLGARLALRAPDAGDRAAGVVAGRNGTLADLTARPISGFDAATA
GLTLFAARASRLLDIELSALEAQGRGQIVSSPRVVTADRTKAVVEQGAELPYQAKVGNGVSGVQFRRATLKLEVEPQITP
DGRVILDLDVAKDSVGEETASGPAIHTKHVQTRVEVENGGTVSIGGIFESDDRDDVTRVPLLGKIPVLGALFRHRAQRAQ
RSELVVYITPTVVIGP
>Mature_576_residues
MMRGFVWVMLGCAIGAAGVAVASPPPLPAGVPAGWAVSASVGAVGRAPLPDAAASRWRIDSERDAVAEAPTPDAGGGAPA
DEFAGDAAPESTSAANSVEPSGSAPAATGLPSRAASVQAEDAALDAVLEGPPVPLSPEQRMSDEHPALPSDTEVASAGAN
ANANANAETAAESDDNRAISLNLQQASLAAVFDAFARFTGLNIVVSERVRGTVSLRLNNVRWRSAFDALLDAHGLAMARR
GSVIWVAPVAELAERERRRFDAHARAAQLEPLASRSFVLRYARAADVQRLLSGSAAQRILSKRGSVLADPRTNLLFVTDL
SGRLAQIADLIGKLDTPSRQVLIEARIVEGDRGFSRNLGARLALRAPDAGDRAAGVVAGRNGTLADLTARPISGFDAATA
GLTLFAARASRLLDIELSALEAQGRGQIVSSPRVVTADRTKAVVEQGAELPYQAKVGNGVSGVQFRRATLKLEVEPQITP
DGRVILDLDVAKDSVGEETASGPAIHTKHVQTRVEVENGGTVSIGGIFESDDRDDVTRVPLLGKIPVLGALFRHRAQRAQ
RSELVVYITPTVVIGP

Specific function: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=403, Percent_Identity=34.7394540942928, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI87082242, Length=390, Percent_Identity=27.9487179487179, Blast_Score=122, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 59997; Mature: 59997

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRGFVWVMLGCAIGAAGVAVASPPPLPAGVPAGWAVSASVGAVGRAPLPDAAASRWRID
CCCHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHCCCC
SERDAVAEAPTPDAGGGAPADEFAGDAAPESTSAANSVEPSGSAPAATGLPSRAASVQAE
CCCCHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHH
DAALDAVLEGPPVPLSPEQRMSDEHPALPSDTEVASAGANANANANAETAAESDDNRAIS
HHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEE
LNLQQASLAAVFDAFARFTGLNIVVSERVRGTVSLRLNNVRWRSAFDALLDAHGLAMARR
EEEHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEEECEEHHHHHHHHHHHHHHHEECC
GSVIWVAPVAELAERERRRFDAHARAAQLEPLASRSFVLRYARAADVQRLLSGSAAQRIL
CCEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SKRGSVLADPRTNLLFVTDLSGRLAQIADLIGKLDTPSRQVLIEARIVEGDRGFSRNLGA
HHCCCEEECCCCCEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCC
RLALRAPDAGDRAAGVVAGRNGTLADLTARPISGFDAATAGLTLFAARASRLLDIELSAL
EEEEECCCCCCCCCEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHEEEEEEEEE
EAQGRGQIVSSPRVVTADRTKAVVEQGAELPYQAKVGNGVSGVQFRRATLKLEVEPQITP
CCCCCCCEECCCEEEECCHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEEEEEECCCCCC
DGRVILDLDVAKDSVGEETASGPAIHTKHVQTRVEVENGGTVSIGGIFESDDRDDVTRVP
CCEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCCEEEECCEECCCCCCCCEECC
LLGKIPVLGALFRHRAQRAQRSELVVYITPTVVIGP
CCCCCHHHHHHHHHHHHHHHHCCEEEEEECEEEECC
>Mature Secondary Structure
MMRGFVWVMLGCAIGAAGVAVASPPPLPAGVPAGWAVSASVGAVGRAPLPDAAASRWRID
CCCHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHCCCC
SERDAVAEAPTPDAGGGAPADEFAGDAAPESTSAANSVEPSGSAPAATGLPSRAASVQAE
CCCCHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHH
DAALDAVLEGPPVPLSPEQRMSDEHPALPSDTEVASAGANANANANAETAAESDDNRAIS
HHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEE
LNLQQASLAAVFDAFARFTGLNIVVSERVRGTVSLRLNNVRWRSAFDALLDAHGLAMARR
EEEHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEEECEEHHHHHHHHHHHHHHHEECC
GSVIWVAPVAELAERERRRFDAHARAAQLEPLASRSFVLRYARAADVQRLLSGSAAQRIL
CCEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SKRGSVLADPRTNLLFVTDLSGRLAQIADLIGKLDTPSRQVLIEARIVEGDRGFSRNLGA
HHCCCEEECCCCCEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCC
RLALRAPDAGDRAAGVVAGRNGTLADLTARPISGFDAATAGLTLFAARASRLLDIELSAL
EEEEECCCCCCCCCEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHEEEEEEEEE
EAQGRGQIVSSPRVVTADRTKAVVEQGAELPYQAKVGNGVSGVQFRRATLKLEVEPQITP
CCCCCCCEECCCEEEECCHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEEEEEECCCCCC
DGRVILDLDVAKDSVGEETASGPAIHTKHVQTRVEVENGGTVSIGGIFESDDRDDVTRVP
CCEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCCEEEECCEECCCCCCCCEECC
LLGKIPVLGALFRHRAQRAQRSELVVYITPTVVIGP
CCCCCHHHHHHHHHHHHHHHHCCEEEEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]