Click here to switch to the map view.

The map label for this gene is cobC [H]

Identifier: 83720683

GI number: 83720683

Start: 955481

End: 956533

Strand: Reverse

Name: cobC [H]

Synonym: BTH_I0841

Alternate gene names: 83720683

Gene position: 956533-955481 (Counterclockwise)

Preceding gene: 83721355

Following gene: 83719364

Centisome position: 25.11

GC content: 75.4

Gene sequence:

>1053_bases
ATGGCTGACGCGCCGATCACGCACGGCGGCAATCTGCACGAAGCCGCCCTTCGCCACGGCATCCCGCGCGACGCATGGCT
CGATCTGTCGACGGGGATCAATCCGCACGGCTATCCGGTGCCGCCCGCGCCCGCCGACGCGTGGCGCCGGCTGCCGGAGG
ACGACGGCGTGCTCGCCGCGCATGCGGCGCGCTACTACGGCGCGCCGGACGCCGCGCACGTGCTGCCCGTCGCCGGCAGC
CAGGCGGCGATCCGCGCGCTGCCCGCGCTGTTCGAGCGCGGCACGGTCGGCGTCGCGCCGCTCGCATACAGCGAGTACGC
GCCCGCGTTCGCGCGCCACGGCCATCCGAGCGCGCCGCTCGACTGCCGTGCCGACCAACTGCCGGCGGCCCTCACGCACG
CGATCGTCGCCAATCCGAACAATCCGACCGCCGAGCGCGTCGACCGCGCACGGCTGCTGCGCTGGCACGCGCAGCTCGTC
GCGCGCGGCGGAGCGCTCGTCGTCGACGAGGCGTTCGCGGATGCCGACACGCACGCGAATGCGTCGCTCGCGCCGGACAC
GCACCTCGACGGCCTCGTCGTGCTGCGCTCGGTCGGCAAGTTCTTCGGGCTTGCCGGCGTGCGCGCGGGCTTCGCGCTCG
CCGCGCCCGCGCTGCTCGCGCGGCTGCGCGACGCGCTCGGCGCGTGGACCGTCAGCGGCCCCGCGCGTCACGCGGTGCTC
GCCGCGTTCGCGGACTCGGCGTGGCAGCACGCGACGCGCGAGCGGCTCGCGCACGACGGCGCGCGCCTCGCCGCGCTGCT
GCGCGCGAACGGCTTCGTCATGCACGCAACGCCGCTCTTCAGTTGGAGCGCCGATCCGCGCGCGCATGCGCTGCATGACG
CGCTCGCCGCGCGCGGAATCTGGACGCGCTACTTCGCGCACGCGCCGAGCGTGCGCATCGGGCTGCCCGCCGGCGAAGAC
GAATGGCGGCGGCTCGAGCGCGCGTTCGCCGAATGCGTGCCGACGCTGCCCGTCGCCTCGCCGCATCCGTCCGGATCGAC
GACACGAGATTGA

Upstream 100 bases:

>100_bases
CCCCCGCACGTCGCGGCGGCGCTGTCGCTCGTCGCCCGCACGATGATTCTCTGGCTCGCGCTGCTGATCGCGGGCGCGGC
ACTATCGATCGCGACGCATC

Downstream 100 bases:

>100_bases
CGCCCATGCGCCTCGCCCTCTCCCGCGCGCTCCTCGCCGCGATCTTTACCGCATGCGCCTGCGCGCTTGCGCCCGCCGTC
GCGCACGCGGAGCTCGCCGT

Product: threonine-phosphate decarboxylase

Products: NA

Alternate protein names: L-threonine-O-3-phosphate decarboxylase [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MADAPITHGGNLHEAALRHGIPRDAWLDLSTGINPHGYPVPPAPADAWRRLPEDDGVLAAHAARYYGAPDAAHVLPVAGS
QAAIRALPALFERGTVGVAPLAYSEYAPAFARHGHPSAPLDCRADQLPAALTHAIVANPNNPTAERVDRARLLRWHAQLV
ARGGALVVDEAFADADTHANASLAPDTHLDGLVVLRSVGKFFGLAGVRAGFALAAPALLARLRDALGAWTVSGPARHAVL
AAFADSAWQHATRERLAHDGARLAALLRANGFVMHATPLFSWSADPRAHALHDALAARGIWTRYFAHAPSVRIGLPAGED
EWRRLERAFAECVPTLPVASPHPSGSTTRD

Sequences:

>Translated_350_residues
MADAPITHGGNLHEAALRHGIPRDAWLDLSTGINPHGYPVPPAPADAWRRLPEDDGVLAAHAARYYGAPDAAHVLPVAGS
QAAIRALPALFERGTVGVAPLAYSEYAPAFARHGHPSAPLDCRADQLPAALTHAIVANPNNPTAERVDRARLLRWHAQLV
ARGGALVVDEAFADADTHANASLAPDTHLDGLVVLRSVGKFFGLAGVRAGFALAAPALLARLRDALGAWTVSGPARHAVL
AAFADSAWQHATRERLAHDGARLAALLRANGFVMHATPLFSWSADPRAHALHDALAARGIWTRYFAHAPSVRIGLPAGED
EWRRLERAFAECVPTLPVASPHPSGSTTRD
>Mature_349_residues
ADAPITHGGNLHEAALRHGIPRDAWLDLSTGINPHGYPVPPAPADAWRRLPEDDGVLAAHAARYYGAPDAAHVLPVAGSQ
AAIRALPALFERGTVGVAPLAYSEYAPAFARHGHPSAPLDCRADQLPAALTHAIVANPNNPTAERVDRARLLRWHAQLVA
RGGALVVDEAFADADTHANASLAPDTHLDGLVVLRSVGKFFGLAGVRAGFALAAPALLARLRDALGAWTVSGPARHAVLA
AFADSAWQHATRERLAHDGARLAALLRANGFVMHATPLFSWSADPRAHALHDALAARGIWTRYFAHAPSVRIGLPAGEDE
WRRLERAFAECVPTLPVASPHPSGSTTRD

Specific function: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1- amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin [H]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005860
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =4.1.1.81 [H]

Molecular weight: Translated: 37061; Mature: 36930

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADAPITHGGNLHEAALRHGIPRDAWLDLSTGINPHGYPVPPAPADAWRRLPEDDGVLAA
CCCCCCCCCCCHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHCCCCCCCEEHH
HAARYYGAPDAAHVLPVAGSQAAIRALPALFERGTVGVAPLAYSEYAPAFARHGHPSAPL
HHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHCCCCCCCC
DCRADQLPAALTHAIVANPNNPTAERVDRARLLRWHAQLVARGGALVVDEAFADADTHAN
CCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHCCCCCCCC
ASLAPDTHLDGLVVLRSVGKFFGLAGVRAGFALAAPALLARLRDALGAWTVSGPARHAVL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
AAFADSAWQHATRERLAHDGARLAALLRANGFVMHATPLFSWSADPRAHALHDALAARGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
WTRYFAHAPSVRIGLPAGEDEWRRLERAFAECVPTLPVASPHPSGSTTRD
HHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ADAPITHGGNLHEAALRHGIPRDAWLDLSTGINPHGYPVPPAPADAWRRLPEDDGVLAA
CCCCCCCCCCHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHCCCCCCCEEHH
HAARYYGAPDAAHVLPVAGSQAAIRALPALFERGTVGVAPLAYSEYAPAFARHGHPSAPL
HHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHCCCCCCCC
DCRADQLPAALTHAIVANPNNPTAERVDRARLLRWHAQLVARGGALVVDEAFADADTHAN
CCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHCCCCCCCC
ASLAPDTHLDGLVVLRSVGKFFGLAGVRAGFALAAPALLARLRDALGAWTVSGPARHAVL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
AAFADSAWQHATRERLAHDGARLAALLRANGFVMHATPLFSWSADPRAHALHDALAARGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
WTRYFAHAPSVRIGLPAGEDEWRRLERAFAECVPTLPVASPHPSGSTTRD
HHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]