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The map label for this gene is glmS [H]

Identifier: 83720543

GI number: 83720543

Start: 494533

End: 495540

Strand: Direct

Name: glmS [H]

Synonym: BTH_I0448

Alternate gene names: 83720543

Gene position: 494533-495540 (Clockwise)

Preceding gene: 83721439

Following gene: 83719492

Centisome position: 12.98

GC content: 73.12

Gene sequence:

>1008_bases
ATGCTTAACGAGGCGCGCGAGTCGGCGCGCGTCGTCGCCGCGCAGCTCGCGGACACGCGCCGCGTCGAGGCGCTCGCGCG
CCATCTCGCCGAGCACGCGCCGCAGGTCGCGCTGACCGTCGCGCGCGGCAGCTCCGATCACGCGGCGAGCTACTTCGCGA
GCCTGACGATGAGCCGCCTCGGCGTGCCCGTCGCGTCGCTGCCGATGTCGGTCGCGACGCTGCAGCAGGCGCCTCTCAAA
GTGCAGGGCCAGCTCGCGCTCGCGTTCTCGCAGTCGGGCAAGAGCCCGGATCTCGTCAACACGATGGCCGCGCTGCGCGA
AGCGGGGGCGCTGACGGTCGCCGCCGTCAACGTGCTGCCGTCGCCGCTCGCCGACGCGTGCGAGCATCAACTGCCGCTGC
TCGCCGGCCCCGAGTTGTCGGTCGCCGCGACGAAGAGCTATATCGCGATGCTGTCGCTCGCCGCGCAGCTCGTCGCGTTC
TGGCAGCGCGACGCCGCGCTCGTGTCCGCGCTGCGCAGCCTGCCCGACGCGCTCGAGCAGGCAGGCCGGTTCGACTGGTC
GAGCGCGGTTGACGAGCTGCGCGGCGTCGAACGGATGATCGTGATCGGCCGCGGGCTCGGCCTCGCGATCGCGCAGGAAG
CGGCGCTCAAGCTGAAGGAGACGTCGGGCATCCAGGCCGAGGCGTTCTCGAGCGCCGAAGTGCGGCACGGCCCGATGGAG
CTCATCGACCGCGACTATCCGCTCCTCGTGTTCGCGCCGCCCGGGCCGGAACAGGAAGGCCTGCTGCAGCTCGCGCGCGA
CATGCGCGCGCGCGGCGCGCGCGTGCTGCTCGCCGCGCCGGCGGGCACGCCCGATGCGACGCTGCCGCTCGCGCGCACCG
CGCACGCGGCGCTCGATCCGATTGCCGCGATCCTGTCGTTCTACGTGATGGCGGCCGGGCTCGCGCGCGCGCGCGGCCGC
GATCCCGATGCGCCGCGCCATCTGCACAAAGTCACCGAAACACACTGA

Upstream 100 bases:

>100_bases
CGCGGGCGCATCGCGCGCGGCGCGTGGGCCGATCTCGCCGTGTTCGACCGCGAACTGAATCTGACCGCAACCTTCGTCGA
AGGAGAATCGATTGTCGAAT

Downstream 100 bases:

>100_bases
CGATCTGACGATCACCGACGAGACGAGACAGCCATGAGACGTGCCGAGGAGTCACAGTTGAAGCAACAAGCATCCCACGA
CCAGATCGTGCTGGTCGCTC

Product: SIS domain-containing protein

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MLNEARESARVVAAQLADTRRVEALARHLAEHAPQVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLK
VQGQLALAFSQSGKSPDLVNTMAALREAGALTVAAVNVLPSPLADACEHQLPLLAGPELSVAATKSYIAMLSLAAQLVAF
WQRDAALVSALRSLPDALEQAGRFDWSSAVDELRGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPPGPEQEGLLQLARDMRARGARVLLAAPAGTPDATLPLARTAHAALDPIAAILSFYVMAAGLARARGR
DPDAPRHLHKVTETH

Sequences:

>Translated_335_residues
MLNEARESARVVAAQLADTRRVEALARHLAEHAPQVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLK
VQGQLALAFSQSGKSPDLVNTMAALREAGALTVAAVNVLPSPLADACEHQLPLLAGPELSVAATKSYIAMLSLAAQLVAF
WQRDAALVSALRSLPDALEQAGRFDWSSAVDELRGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPPGPEQEGLLQLARDMRARGARVLLAAPAGTPDATLPLARTAHAALDPIAAILSFYVMAAGLARARGR
DPDAPRHLHKVTETH
>Mature_335_residues
MLNEARESARVVAAQLADTRRVEALARHLAEHAPQVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLK
VQGQLALAFSQSGKSPDLVNTMAALREAGALTVAAVNVLPSPLADACEHQLPLLAGPELSVAATKSYIAMLSLAAQLVAF
WQRDAALVSALRSLPDALEQAGRFDWSSAVDELRGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPPGPEQEGLLQLARDMRARGARVLLAAPAGTPDATLPLARTAHAALDPIAAILSFYVMAAGLARARGR
DPDAPRHLHKVTETH

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=262, Percent_Identity=27.0992366412214, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI205277386, Length=261, Percent_Identity=26.4367816091954, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1790167, Length=322, Percent_Identity=31.055900621118, Blast_Score=106, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17532899, Length=329, Percent_Identity=24.9240121580547, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17532897, Length=329, Percent_Identity=24.9240121580547, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17539970, Length=329, Percent_Identity=24.9240121580547, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322745, Length=309, Percent_Identity=25.5663430420712, Blast_Score=93, Evalue=7e-20,
Organism=Drosophila melanogaster, GI21357745, Length=323, Percent_Identity=23.5294117647059, Blast_Score=101, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 35315; Mature: 35315

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNEARESARVVAAQLADTRRVEALARHLAEHAPQVALTVARGSSDHAASYFASLTMSRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHH
GVPVASLPMSVATLQQAPLKVQGQLALAFSQSGKSPDLVNTMAALREAGALTVAAVNVLP
CCCHHHHHHHHHHHHHCCCEECCEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHCC
SPLADACEHQLPLLAGPELSVAATKSYIAMLSLAAQLVAFWQRDAALVSALRSLPDALEQ
CHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGRFDWSSAVDELRGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
HCCCCHHHHHHHHHCHHHEEEEECCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCCHH
LIDRDYPLLVFAPPGPEQEGLLQLARDMRARGARVLLAAPAGTPDATLPLARTAHAALDP
HHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
IAAILSFYVMAAGLARARGRDPDAPRHLHKVTETH
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MLNEARESARVVAAQLADTRRVEALARHLAEHAPQVALTVARGSSDHAASYFASLTMSRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHH
GVPVASLPMSVATLQQAPLKVQGQLALAFSQSGKSPDLVNTMAALREAGALTVAAVNVLP
CCCHHHHHHHHHHHHHCCCEECCEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHCC
SPLADACEHQLPLLAGPELSVAATKSYIAMLSLAAQLVAFWQRDAALVSALRSLPDALEQ
CHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGRFDWSSAVDELRGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
HCCCCHHHHHHHHHCHHHEEEEECCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCCHH
LIDRDYPLLVFAPPGPEQEGLLQLARDMRARGARVLLAAPAGTPDATLPLARTAHAALDP
HHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHH
IAAILSFYVMAAGLARARGRDPDAPRHLHKVTETH
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]