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The map label for this gene is btuB [H]

Identifier: 83720463

GI number: 83720463

Start: 947977

End: 950019

Strand: Direct

Name: btuB [H]

Synonym: BTH_I0834

Alternate gene names: 83720463

Gene position: 947977-950019 (Clockwise)

Preceding gene: 83721368

Following gene: 83718866

Centisome position: 24.89

GC content: 68.18

Gene sequence:

>2043_bases
ATGCGAACCCCACTCGTGCGCGCAGCGCTCGCCGCTCTGTCCGGGCTGCCATGCATCGCGCTCGCGCGAGGCGACGCCGC
GGCGTCGCCGCCCCCATCCGCTTACCCCGCCGCTTACGCGTCGGCTGCGTCGCCGTCCGCCGCCGCGGCGCCTGCGGCGG
ATGCCGCGATGTCGACGACGCCCGCCGCTTCGGCGAATGCCGCATCGTTCGCGTTCGCGGCCTCCGGCGCATCGGAAGCG
CTCTCGGCATCGCCGGCGCGCTCGCGCCCGGCATCGGTCGAGCCGCTCGCGCCGATCGTCGTTACCGCGCAGCGCGGGCA
GCAGAAGCTCGCCGATGCGATTCCGCAGACGACGCTCTTCGATGCGCAGGACATCGCCGACAGCGGCGCGACCGATCTGC
CCGGCCTGCTCGCGCTCGCGCCGGGCGCGCAGATCGTGCGCAACGGCGGGCCGGGCGCGAGCGCGAGCCTGTTCCTGCGC
GGCGCGCAGTCGACGCAATCGCTCGTGCTGATCGACGGCGTGCGCATCGATTCGGCGAGCCTCGGCCGGGCGCAGATCGA
CCAGTTGCCGCTCGATCAGATCGAGCGCGTCGAAGTGGTGAACGGCAACGTGTCTTCGCTGTACGGGTCGGGTGCGATCG
GCGGCGTCGTGCAGGTGTTCACGAAGAACGGCGGCAATCATCCGCCGCGCTTCGATTTCTCCGTGGGCTACGGCAGCTAT
CACACGCAGACGCAAAGCGCGGGCGCGTCGGGCCGACTCGACGAGGACGGCAAGACGACGTTCAGCGTGTCGCTCGCGCG
GCTGAAGACCGACGGTTTCTCCGCGCTCGATCCCGCGCGCAAGCCGCAGGCGAATCCGAACGCGAACGGTTTTCTGAGCG
AGAGCGCGTCCGCGTCGCTGCGGCACCGGTTCAGCGACAAGTGGGATGCGGGCGTCACGTACTTCCAGGCGAACGGCCGC
AACAGCTACGACGACGCGTACGGCTCGCCGACCGATCTGAACGACCTGTACAGCCGCGTTCAGCAACTGTCCGCGTTCGC
GAACGGCAAGCTCGCCGATTGGTGGACGACGCGCGTGAACGTGTCGAGCGGCAAGGACCGCAGCCAGTCGGCGCTGAACG
GCGCATACACCGACCACTTCAATTCCGGCAACCGTCAGTACACGTGGCAGAACGATTTCACGGTCGCGCGCGGGCACAAG
ATCCAGGCGGGGTACGAGCGGCTCGACCAGTCGTTCGAATCGAACAGGTATTCGGCGCCCGACCGCCATGTGAATTCCGG
CTGGCTCGGCTATACCGGACGCCTCGGCGACAGCCAGTTCCAGGCGAACGTGCGCCGTGACCAGTACTCCGATTTCGGCG
GCGCGAACAGCTACTTTCTCGGCTACGGGTTCGACGTCACCGAGCGCTGGAAGGTGTCGGCGAGCTATTCGAGCGCGTTT
CGCGCGCCGAGCTTCAACGATCTGTACTATCCGAACGCGGGCAACCTGGCGATCAAGCCGGAGCGCAGCCATTCGGTCGA
GGCGGCCGTGCAGTATGCGTCGGATGCGGTGGGCGTCGTGCGCGTCACCGCGTTTCAGACGCGCTACACGAACCTGATCG
ACTATCGTCCCGGCGCGAGCGGCCCATACTATGTCGCGCAGAACGTCGGCCGCGCGAAGGTGCAGGGCGTCGAGGGATCG
TGGCAGGGGCATGTCGGCAAGACCGATGTGCGCGTGGCCGCGACGCTGCAGAACCCGATCGACGAAACCGCCGGCCAGGA
TCTGAACCGACGCGCGCGGCGCTTCGCGTCGATCTCGGCGCACCGCTCGCTCGGCGGCTGGCGCGTCGGCGGCGAATGGC
TCGTGAGCGGGCCGCGCGACGATTTCGGCGATCATCTCGGCGGATACGGCGTCGTCAATCTGTCCGCGCGCTACGACATC
ACGAAGTCGTGGTACGTGAGCGCGCGCATCGACAATCTGTTCGACAAGGACTACGAGCTTGCCTATGCATACAACACGCC
GCGCCGCGGCGCCTACGTCACGCTCGGCTGGCAGCAGCGCTGA

Upstream 100 bases:

>100_bases
GCCCGGATACCGGCCGAGGCGGGGAGACGGACGCGTTCGTCTCCGTGATGCGGGCCTGCGGGGAAGCGGGCTCCGCAGTG
CCTCAACAGGATCTTCGTTC

Downstream 100 bases:

>100_bases
CGGCCGGCCGCGTCGCCGGCGCGGCGCGCGCGGCCGCGCGCGGGAGGTCGCATGAGGCCGCGGGCGCGCGGCGCCGGCAT
GCATGCGGCGCGGGCGGCCG

Product: vitamin B12 receptor BtuB

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MRTPLVRAALAALSGLPCIALARGDAAASPPPSAYPAAYASAASPSAAAAPAADAAMSTTPAASANAASFAFAASGASEA
LSASPARSRPASVEPLAPIVVTAQRGQQKLADAIPQTTLFDAQDIADSGATDLPGLLALAPGAQIVRNGGPGASASLFLR
GAQSTQSLVLIDGVRIDSASLGRAQIDQLPLDQIERVEVVNGNVSSLYGSGAIGGVVQVFTKNGGNHPPRFDFSVGYGSY
HTQTQSAGASGRLDEDGKTTFSVSLARLKTDGFSALDPARKPQANPNANGFLSESASASLRHRFSDKWDAGVTYFQANGR
NSYDDAYGSPTDLNDLYSRVQQLSAFANGKLADWWTTRVNVSSGKDRSQSALNGAYTDHFNSGNRQYTWQNDFTVARGHK
IQAGYERLDQSFESNRYSAPDRHVNSGWLGYTGRLGDSQFQANVRRDQYSDFGGANSYFLGYGFDVTERWKVSASYSSAF
RAPSFNDLYYPNAGNLAIKPERSHSVEAAVQYASDAVGVVRVTAFQTRYTNLIDYRPGASGPYYVAQNVGRAKVQGVEGS
WQGHVGKTDVRVAATLQNPIDETAGQDLNRRARRFASISAHRSLGGWRVGGEWLVSGPRDDFGDHLGGYGVVNLSARYDI
TKSWYVSARIDNLFDKDYELAYAYNTPRRGAYVTLGWQQR

Sequences:

>Translated_680_residues
MRTPLVRAALAALSGLPCIALARGDAAASPPPSAYPAAYASAASPSAAAAPAADAAMSTTPAASANAASFAFAASGASEA
LSASPARSRPASVEPLAPIVVTAQRGQQKLADAIPQTTLFDAQDIADSGATDLPGLLALAPGAQIVRNGGPGASASLFLR
GAQSTQSLVLIDGVRIDSASLGRAQIDQLPLDQIERVEVVNGNVSSLYGSGAIGGVVQVFTKNGGNHPPRFDFSVGYGSY
HTQTQSAGASGRLDEDGKTTFSVSLARLKTDGFSALDPARKPQANPNANGFLSESASASLRHRFSDKWDAGVTYFQANGR
NSYDDAYGSPTDLNDLYSRVQQLSAFANGKLADWWTTRVNVSSGKDRSQSALNGAYTDHFNSGNRQYTWQNDFTVARGHK
IQAGYERLDQSFESNRYSAPDRHVNSGWLGYTGRLGDSQFQANVRRDQYSDFGGANSYFLGYGFDVTERWKVSASYSSAF
RAPSFNDLYYPNAGNLAIKPERSHSVEAAVQYASDAVGVVRVTAFQTRYTNLIDYRPGASGPYYVAQNVGRAKVQGVEGS
WQGHVGKTDVRVAATLQNPIDETAGQDLNRRARRFASISAHRSLGGWRVGGEWLVSGPRDDFGDHLGGYGVVNLSARYDI
TKSWYVSARIDNLFDKDYELAYAYNTPRRGAYVTLGWQQR
>Mature_680_residues
MRTPLVRAALAALSGLPCIALARGDAAASPPPSAYPAAYASAASPSAAAAPAADAAMSTTPAASANAASFAFAASGASEA
LSASPARSRPASVEPLAPIVVTAQRGQQKLADAIPQTTLFDAQDIADSGATDLPGLLALAPGAQIVRNGGPGASASLFLR
GAQSTQSLVLIDGVRIDSASLGRAQIDQLPLDQIERVEVVNGNVSSLYGSGAIGGVVQVFTKNGGNHPPRFDFSVGYGSY
HTQTQSAGASGRLDEDGKTTFSVSLARLKTDGFSALDPARKPQANPNANGFLSESASASLRHRFSDKWDAGVTYFQANGR
NSYDDAYGSPTDLNDLYSRVQQLSAFANGKLADWWTTRVNVSSGKDRSQSALNGAYTDHFNSGNRQYTWQNDFTVARGHK
IQAGYERLDQSFESNRYSAPDRHVNSGWLGYTGRLGDSQFQANVRRDQYSDFGGANSYFLGYGFDVTERWKVSASYSSAF
RAPSFNDLYYPNAGNLAIKPERSHSVEAAVQYASDAVGVVRVTAFQTRYTNLIDYRPGASGPYYVAQNVGRAKVQGVEGS
WQGHVGKTDVRVAATLQNPIDETAGQDLNRRARRFASISAHRSLGGWRVGGEWLVSGPRDDFGDHLGGYGVVNLSARYDI
TKSWYVSARIDNLFDKDYELAYAYNTPRRGAYVTLGWQQR

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG4206

COG function: function code H; Outer membrane cobalamin receptor protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790405, Length=610, Percent_Identity=29.344262295082, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1788478, Length=131, Percent_Identity=36.6412213740458, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 72606; Mature: 72606

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTPLVRAALAALSGLPCIALARGDAAASPPPSAYPAAYASAASPSAAAAPAADAAMSTT
CCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHCCC
PAASANAASFAFAASGASEALSASPARSRPASVEPLAPIVVTAQRGQQKLADAIPQTTLF
CCCCCCCCEEEEECCCCHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCEEE
DAQDIADSGATDLPGLLALAPGAQIVRNGGPGASASLFLRGAQSTQSLVLIDGVRIDSAS
CHHHHHCCCCCCCCCCEEECCCHHEEECCCCCCCEEEEEEECCCCCEEEEEECEEECCCC
LGRAQIDQLPLDQIERVEVVNGNVSSLYGSGAIGGVVQVFTKNGGNHPPRFDFSVGYGSY
CCHHHHHCCCHHHHCEEEEECCCHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCC
HTQTQSAGASGRLDEDGKTTFSVSLARLKTDGFSALDPARKPQANPNANGFLSESASASL
CCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCHHHHH
RHRFSDKWDAGVTYFQANGRNSYDDAYGSPTDLNDLYSRVQQLSAFANGKLADWWTTRVN
HHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEE
VSSGKDRSQSALNGAYTDHFNSGNRQYTWQNDFTVARGHKIQAGYERLDQSFESNRYSAP
CCCCCCHHHHHHCCCCCCCCCCCCEEEEECCCEEEECCCEEHHHHHHHHHHHHCCCCCCC
DRHVNSGWLGYTGRLGDSQFQANVRRDQYSDFGGANSYFLGYGFDVTERWKVSASYSSAF
CCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEECHHHHC
RAPSFNDLYYPNAGNLAIKPERSHSVEAAVQYASDAVGVVRVTAFQTRYTNLIDYRPGAS
CCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHCCCCEEEEEEEEHHHHHHHEECCCCCC
GPYYVAQNVGRAKVQGVEGSWQGHVGKTDVRVAATLQNPIDETAGQDLNRRARRFASISA
CCCHHHCCCCCEEEECCCCCCCCCCCCCCEEEEEEHHCHHHHHHCCHHHHHHHHHHHHHH
HRSLGGWRVGGEWLVSGPRDDFGDHLGGYGVVNLSARYDITKSWYVSARIDNLFDKDYEL
HHCCCCEEECCEEEECCCCHHHHHHCCCCEEEEEEEEEECCCEEEEEEEHHHHCCCCCEE
AYAYNTPRRGAYVTLGWQQR
EEEECCCCCCEEEEEECCCC
>Mature Secondary Structure
MRTPLVRAALAALSGLPCIALARGDAAASPPPSAYPAAYASAASPSAAAAPAADAAMSTT
CCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHCCC
PAASANAASFAFAASGASEALSASPARSRPASVEPLAPIVVTAQRGQQKLADAIPQTTLF
CCCCCCCCEEEEECCCCHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCEEE
DAQDIADSGATDLPGLLALAPGAQIVRNGGPGASASLFLRGAQSTQSLVLIDGVRIDSAS
CHHHHHCCCCCCCCCCEEECCCHHEEECCCCCCCEEEEEEECCCCCEEEEEECEEECCCC
LGRAQIDQLPLDQIERVEVVNGNVSSLYGSGAIGGVVQVFTKNGGNHPPRFDFSVGYGSY
CCHHHHHCCCHHHHCEEEEECCCHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCC
HTQTQSAGASGRLDEDGKTTFSVSLARLKTDGFSALDPARKPQANPNANGFLSESASASL
CCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCHHHHH
RHRFSDKWDAGVTYFQANGRNSYDDAYGSPTDLNDLYSRVQQLSAFANGKLADWWTTRVN
HHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEE
VSSGKDRSQSALNGAYTDHFNSGNRQYTWQNDFTVARGHKIQAGYERLDQSFESNRYSAP
CCCCCCHHHHHHCCCCCCCCCCCCEEEEECCCEEEECCCEEHHHHHHHHHHHHCCCCCCC
DRHVNSGWLGYTGRLGDSQFQANVRRDQYSDFGGANSYFLGYGFDVTERWKVSASYSSAF
CCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEECHHHHC
RAPSFNDLYYPNAGNLAIKPERSHSVEAAVQYASDAVGVVRVTAFQTRYTNLIDYRPGAS
CCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHCCCCEEEEEEEEHHHHHHHEECCCCCC
GPYYVAQNVGRAKVQGVEGSWQGHVGKTDVRVAATLQNPIDETAGQDLNRRARRFASISA
CCCHHHCCCCCEEEECCCCCCCCCCCCCCEEEEEEHHCHHHHHHCCHHHHHHHHHHHHHH
HRSLGGWRVGGEWLVSGPRDDFGDHLGGYGVVNLSARYDITKSWYVSARIDNLFDKDYEL
HHCCCCEEECCEEEECCCCHHHHHHCCCCEEEEEEEEEECCCEEEEEEEHHHHCCCCCEE
AYAYNTPRRGAYVTLGWQQR
EEEECCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA