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The map label for this gene is phbC [H]

Identifier: 83720440

GI number: 83720440

Start: 2536388

End: 2538358

Strand: Direct

Name: phbC [H]

Synonym: BTH_I2255

Alternate gene names: 83720440

Gene position: 2536388-2538358 (Clockwise)

Preceding gene: 83721548

Following gene: 83719964

Centisome position: 66.59

GC content: 66.06

Gene sequence:

>1971_bases
GTGGGTGGTCGACTTCATGCGGCTCGAGCAGGATTTCCAGGGTCCCCGCAGGCAACACCGAGGAAACACCGAGGAACCAC
CGTTAAGGCAGGTATGACAGCATCGAAAAAATCGTCGACGTCCTCTCACACGGATACTTCCCAGGGTCGCAACGCAGCCG
GATCGGCGGCCCAGCCCATGCAACAGTTGTTCGAGTCCTGGCTCGACGCGTGGCGCAGCTTCGCGGACCCGGCCCGGGCG
AGCGCTGGCGGCGCGCCCGCGCAGCCGCCGTTCGCGGCGTTCCAGGCGCCTCAACTGTTCCCGTTCGCGATGCCTAAGAT
GCCGCCGATGCCGGACTGGTCCGGCGGCGCGCCCGCGTCGCTCGCGCCCGTCGCGTCGGTGCCGCCCGCGCGGCTGCAGA
AGCTGCAGGCCGATTACGCGCGCGATTGCCTCGCGCTGATCCAGCAGGCAAGCGCCGCGGCGCCGACCGTTCCCGAGCTG
AAGGATCGGCGTTTCAGCTCGGATGCATGGAAGGCTTCGCCCGCGCACGGATTCGCGGCCGCGTGGTATCTGCTGAACGC
GCGCTATCTGCAGGAGCTTGCCGACGCGCTCGAGACCGATCCGAAGACGCGCGAGCGGATCCGCTTCACGGTCCAGCAGT
GGACGGCCGCCGCGTCGCCGAGCAACTTTCTCGCGCTCAATCCTGAGGCGCAGAAGAATCTCGTCGAGACGCAGGGCGAG
AGCCTGCGTCTCGGGATGATGAACCTGCTCGCGGACATGCGGCGCGGCAAGATCACGCAGACGGACGAATCGCAATTCGT
CGTCGGCAAGAATCTCGCGGTGACACCGGGCGCGATCGTCTACGAGAACGATCTGATCCAGCTGATCCAGTACAAGCCGA
CGACGGCAACCGTCTTCGAGCGGCCGCTCCTCATCGTGCCGCCTTGCATCAACAAGTTCTACATCCTCGATCTGCAGCCG
GAGAACTCGCTCGTCGCGCACGCGCTGTCGTGCGGCCATCAGGTGTTTCTCGTGTCGTGGCGCAACGCCGATGCGTTGGT
CTCGCACAAGACGTGGGACGACTACATCGACGAGGGGCTGCTCGCCGCGATCGACGTCGTCCAGCAGGTGAGCGGGCGCG
AGCAGATCAACACGCTCGGTTTTTGCGTCGGCGGCACGATGCTGGCCACGGCGCTCGCGGTGCTCGCCGCGCGCGGCGAG
CATCCGGCCGCGTCGATGACGCTCCTCACCGCGATGCTCGATTTTTCCGACACGGGCATCCTCGACGTGTTCGTCGACGA
AGCGCACGTGCAGATGCGCGAGCAGACCATCGGCGGCAAGAACGGCGCGCCCGCGGGCTTGATGCGCGGCGTCGAGTTCG
CGAACACGTTTTCGTTTCTGCGTCCGAACGATCTCGTGTGGAACTACGTCGTCGACAACTACCTGAAGGGCCGCACGCCG
GCGCCGTTCGATCTGCTGTACTGGAACGGCGATTCGACGAGCCTGCCGGGGCCGATGTACGCGTGGTATCTGCGAAACAC
CTATCTCGAGAACAAGCTGCGCGAGCCGGATGCGCTCACCGTGTGCGGCGAGCCCGTCGATCTGTCGCGGATCGACGTGC
CGACGTTCATCTACGGCTCGCGCGAGGATCACATCGTGCCGTGGCAGACCGCGTACGAATCGACGTCGCTGCTGACGGGG
CCGCTGAAGTTCGTGCTCGGCGCATCGGGCCACATCGCGGGCGTGATCAACCCGCCTGCGAAGCACAAGCGCAGCTACTG
GAGCTATGACGCCGATGCGAAGGCGCTGCCGGAATCGGCGAACGACTGGCTCGACGCGGCCGTCGAGCATCCGGGCAGCT
GGTGGCCGGTGTGGATCGAGTGGCTCGATCAGTACGGCGGAAAGAAGGTGAAGCCGCGCGGGCAGCTCGGCTCCGCGCAC
TTCCCGGTGATCGAGCCTGCGCCCGGCCGGTATGTGATGCAACGCGATTGA

Upstream 100 bases:

>100_bases
GTGACGGATCACATGGGGAAAACGATAATGATAAAACTACTGCACTGCGGCAGAATCTGGAGAAGCGCTCCGGAACACGC
CCGGCTGAACGGGGCGCGCA

Downstream 100 bases:

>100_bases
CGAACGACGGAAGGCGGAGCACGCTTTGCGTCGCTACCGATTTTTAACAGGGCGGTTCGCGGCGCGCCGTGCCGCGTTCG
CTCGGAGGATAGTGAAATGA

Product: poly(R)-hydroxyalkanoic acid synthase, class I

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 656; Mature: 655

Protein sequence:

>656_residues
MGGRLHAARAGFPGSPQATPRKHRGTTVKAGMTASKKSSTSSHTDTSQGRNAAGSAAQPMQQLFESWLDAWRSFADPARA
SAGGAPAQPPFAAFQAPQLFPFAMPKMPPMPDWSGGAPASLAPVASVPPARLQKLQADYARDCLALIQQASAAAPTVPEL
KDRRFSSDAWKASPAHGFAAAWYLLNARYLQELADALETDPKTRERIRFTVQQWTAAASPSNFLALNPEAQKNLVETQGE
SLRLGMMNLLADMRRGKITQTDESQFVVGKNLAVTPGAIVYENDLIQLIQYKPTTATVFERPLLIVPPCINKFYILDLQP
ENSLVAHALSCGHQVFLVSWRNADALVSHKTWDDYIDEGLLAAIDVVQQVSGREQINTLGFCVGGTMLATALAVLAARGE
HPAASMTLLTAMLDFSDTGILDVFVDEAHVQMREQTIGGKNGAPAGLMRGVEFANTFSFLRPNDLVWNYVVDNYLKGRTP
APFDLLYWNGDSTSLPGPMYAWYLRNTYLENKLREPDALTVCGEPVDLSRIDVPTFIYGSREDHIVPWQTAYESTSLLTG
PLKFVLGASGHIAGVINPPAKHKRSYWSYDADAKALPESANDWLDAAVEHPGSWWPVWIEWLDQYGGKKVKPRGQLGSAH
FPVIEPAPGRYVMQRD

Sequences:

>Translated_656_residues
MGGRLHAARAGFPGSPQATPRKHRGTTVKAGMTASKKSSTSSHTDTSQGRNAAGSAAQPMQQLFESWLDAWRSFADPARA
SAGGAPAQPPFAAFQAPQLFPFAMPKMPPMPDWSGGAPASLAPVASVPPARLQKLQADYARDCLALIQQASAAAPTVPEL
KDRRFSSDAWKASPAHGFAAAWYLLNARYLQELADALETDPKTRERIRFTVQQWTAAASPSNFLALNPEAQKNLVETQGE
SLRLGMMNLLADMRRGKITQTDESQFVVGKNLAVTPGAIVYENDLIQLIQYKPTTATVFERPLLIVPPCINKFYILDLQP
ENSLVAHALSCGHQVFLVSWRNADALVSHKTWDDYIDEGLLAAIDVVQQVSGREQINTLGFCVGGTMLATALAVLAARGE
HPAASMTLLTAMLDFSDTGILDVFVDEAHVQMREQTIGGKNGAPAGLMRGVEFANTFSFLRPNDLVWNYVVDNYLKGRTP
APFDLLYWNGDSTSLPGPMYAWYLRNTYLENKLREPDALTVCGEPVDLSRIDVPTFIYGSREDHIVPWQTAYESTSLLTG
PLKFVLGASGHIAGVINPPAKHKRSYWSYDADAKALPESANDWLDAAVEHPGSWWPVWIEWLDQYGGKKVKPRGQLGSAH
FPVIEPAPGRYVMQRD
>Mature_655_residues
GGRLHAARAGFPGSPQATPRKHRGTTVKAGMTASKKSSTSSHTDTSQGRNAAGSAAQPMQQLFESWLDAWRSFADPARAS
AGGAPAQPPFAAFQAPQLFPFAMPKMPPMPDWSGGAPASLAPVASVPPARLQKLQADYARDCLALIQQASAAAPTVPELK
DRRFSSDAWKASPAHGFAAAWYLLNARYLQELADALETDPKTRERIRFTVQQWTAAASPSNFLALNPEAQKNLVETQGES
LRLGMMNLLADMRRGKITQTDESQFVVGKNLAVTPGAIVYENDLIQLIQYKPTTATVFERPLLIVPPCINKFYILDLQPE
NSLVAHALSCGHQVFLVSWRNADALVSHKTWDDYIDEGLLAAIDVVQQVSGREQINTLGFCVGGTMLATALAVLAARGEH
PAASMTLLTAMLDFSDTGILDVFVDEAHVQMREQTIGGKNGAPAGLMRGVEFANTFSFLRPNDLVWNYVVDNYLKGRTPA
PFDLLYWNGDSTSLPGPMYAWYLRNTYLENKLREPDALTVCGEPVDLSRIDVPTFIYGSREDHIVPWQTAYESTSLLTGP
LKFVLGASGHIAGVINPPAKHKRSYWSYDADAKALPESANDWLDAAVEHPGSWWPVWIEWLDQYGGKKVKPRGQLGSAHF
PVIEPAPGRYVMQRD

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010963
- InterPro:   IPR010941 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF07167 PhaC_N [H]

EC number: NA

Molecular weight: Translated: 71771; Mature: 71640

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGRLHAARAGFPGSPQATPRKHRGTTVKAGMTASKKSSTSSHTDTSQGRNAAGSAAQPM
CCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
QQLFESWLDAWRSFADPARASAGGAPAQPPFAAFQAPQLFPFAMPKMPPMPDWSGGAPAS
HHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
LAPVASVPPARLQKLQADYARDCLALIQQASAAAPTVPELKDRRFSSDAWKASPAHGFAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCHHHH
AWYLLNARYLQELADALETDPKTRERIRFTVQQWTAAASPSNFLALNPEAQKNLVETQGE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHCCC
SLRLGMMNLLADMRRGKITQTDESQFVVGKNLAVTPGAIVYENDLIQLIQYKPTTATVFE
CEEHHHHHHHHHHHCCCCCCCCCCCEEECCCEEECCCCEEECCCHHHHHHCCCCCHHHHC
RPLLIVPPCINKFYILDLQPENSLVAHALSCGHQVFLVSWRNADALVSHKTWDDYIDEGL
CCCEEECCCCCCEEEEEECCCCHHHHHHHHCCCEEEEEEECCCCCEEECCCHHHHHHHHH
LAAIDVVQQVSGREQINTLGFCVGGTMLATALAVLAARGEHPAASMTLLTAMLDFSDTGI
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCE
LDVFVDEAHVQMREQTIGGKNGAPAGLMRGVEFANTFSFLRPNDLVWNYVVDNYLKGRTP
EEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
APFDLLYWNGDSTSLPGPMYAWYLRNTYLENKLREPDALTVCGEPVDLSRIDVPTFIYGS
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCEEEECC
REDHIVPWQTAYESTSLLTGPLKFVLGASGHIAGVINPPAKHKRSYWSYDADAKALPESA
CCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCHHHCCCCCCCCCCHHHCCCCH
NDWLDAAVEHPGSWWPVWIEWLDQYGGKKVKPRGQLGSAHFPVIEPAPGRYVMQRD
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCEEEECC
>Mature Secondary Structure 
GGRLHAARAGFPGSPQATPRKHRGTTVKAGMTASKKSSTSSHTDTSQGRNAAGSAAQPM
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
QQLFESWLDAWRSFADPARASAGGAPAQPPFAAFQAPQLFPFAMPKMPPMPDWSGGAPAS
HHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
LAPVASVPPARLQKLQADYARDCLALIQQASAAAPTVPELKDRRFSSDAWKASPAHGFAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCHHHH
AWYLLNARYLQELADALETDPKTRERIRFTVQQWTAAASPSNFLALNPEAQKNLVETQGE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHCCC
SLRLGMMNLLADMRRGKITQTDESQFVVGKNLAVTPGAIVYENDLIQLIQYKPTTATVFE
CEEHHHHHHHHHHHCCCCCCCCCCCEEECCCEEECCCCEEECCCHHHHHHCCCCCHHHHC
RPLLIVPPCINKFYILDLQPENSLVAHALSCGHQVFLVSWRNADALVSHKTWDDYIDEGL
CCCEEECCCCCCEEEEEECCCCHHHHHHHHCCCEEEEEEECCCCCEEECCCHHHHHHHHH
LAAIDVVQQVSGREQINTLGFCVGGTMLATALAVLAARGEHPAASMTLLTAMLDFSDTGI
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCE
LDVFVDEAHVQMREQTIGGKNGAPAGLMRGVEFANTFSFLRPNDLVWNYVVDNYLKGRTP
EEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
APFDLLYWNGDSTSLPGPMYAWYLRNTYLENKLREPDALTVCGEPVDLSRIDVPTFIYGS
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCEEEECC
REDHIVPWQTAYESTSLLTGPLKFVLGASGHIAGVINPPAKHKRSYWSYDADAKALPESA
CCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCHHHCCCCCCCCCCHHHCCCCH
NDWLDAAVEHPGSWWPVWIEWLDQYGGKKVKPRGQLGSAHFPVIEPAPGRYVMQRD
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2670936; 1987116 [H]