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The map label for this gene is aspS [H]

Identifier: 83720369

GI number: 83720369

Start: 637264

End: 639066

Strand: Direct

Name: aspS [H]

Synonym: BTH_I0560

Alternate gene names: 83720369

Gene position: 637264-639066 (Clockwise)

Preceding gene: 83719228

Following gene: 83721114

Centisome position: 16.73

GC content: 65.45

Gene sequence:

>1803_bases
ATGTCGATGCGAACTGAATACTGCGGTCTCGTGACCGAACACCTGCTGGGCCAAACCGTGTCGCTGTGCGGCTGGGTGCA
GCGCCGCCGCGATCACGGCGGTGTGATCTTCATCGACCTGCGCGATCGTGAAGGCCTCGTGCAGGTGGTCTGCGATCCGG
ATCGCGCGGAGATGTTCGCGACCGCCGAAGGCGTGCGCAACGAGTTCTGCGTGCAGGTGAAGGGGCTTGTGCGCAACCGT
CCGGAAGGCACGGTCAACGCCGGCCTGAAGAGCGGCAAGATCGAGGTGCTGTGCCACGAGCTGACCGTGCTGAACGCGTC
GGTCACACCGCCGTTCCAGCTCGACGACGACAACCTGTCGGAAACGACGCGCCTCACGCACCGCGTGCTCGACCTGCGCC
GTCCGCAGATGCAGCACAACCTGCGCCTGCGCTACCGCGTCGCGATCGAGGCGCGCAAGTATCTCGACGAGCAGGGTTTC
ATCGACATCGAAACGCCGATGCTGACGAAGAGCACGCCGGAAGGCGCGCGCGACTACCTCGTGCCGTCGCGCGTGAACGC
GGGCCAGTTCTTCGCGCTGCCGCAGTCGCCGCAGCTGTTCAAGCAGTTGCTGATGGTCGCGAACTTCGACCGTTACTACC
AGATCACGAAGTGCTTCCGCGACGAGGACCTGCGCGCGGACCGCCAGCCGGAATTCACGCAGATCGACTGCGAGACGTCG
TTCCTCGGCGAGCAGGAAATTCGCGATCTGTTCGAGGACATGATCCGTCATATCTTCAAGACGACGATCGACGTCGAGCT
CGACGCGAAATTCCCGGTGATGCCGTATTCGGAAGCGATGGCGCGCTTCGGCTCGGACAAGCCCGACCTGCGCGTGAAGC
TCGAGTTCACCGAGCTCACCGACGCGATGAAGGACGTCGATTTCAAGGTGTTCAGCACGCCGGCCAATACGAAGGACGGC
CGCGTCGCGGCGCTGCGCGTGCCGAAGGGCGCCGAGCTCACGCGCGGCGATATCGACGGCTACACCGAATTCGTGCGCAT
CTACGGCGCGAAGGGCCTCGCGTGGATCAAGGTCAACGAGCGCGCGAAGGGCCGCGACGGCCTGCAGAGCCCGATCGTCA
AGAACCTGCACGACGCGTCGATCGCGGCGATTCTCGAGCGCACGGGCGCGCAAGACGGCGACATCGTCTTCTTCGCGGCC
GACCGCGCGAAGGTCGTCAACGACAGCCTCGGCGCGCTGCGCCTGAAGATCGGCCACTCGGAGTTCGGCAAGGCGAACGG
CCTCGTCGAGTCGGGCTGGAAGCCGCTGTGGGTCGTCGATTTTCCGATGTTCGAGTACGACGACGAGGAAGCGCGCTACG
TCGCGGCGCACCATCCGTTCACGAGCCCGAAGGACGAGCATCTCGAATATCTCGAGACCGATCCGGGCCGCTGCCTCGCG
AAGGCGTACGACATGGTGCTGAACGGCTGGGAAATCGGCGGCGGCTCGGTGCGTATCCACCGCGAGGAAGTGCAGAGCAA
GGTGTTCCGCGCGCTGAAGATCGGCCCGGAGGAGGCGCAGGCGAAGTTCGGCTTCCTGCTCGACGCGCTGCAATACGGTG
CACCGCCGCACGGCGGCATCGCGTTCGGCCTCGATCGCATCGTCACGATGATGGCGGGCGCCGATTCGATCCGCGACGTG
ATCGCGTTCCCGAAGACGCAGCGCGCGCAGTGTCTGCTCACGCAGGCACCGAGCCCCGTCGACGAGCGCCAGCTGCGCGA
GCTGCACATCCGCCTGCGTCAGCCGGAGCAGCCGAAGGCGTAA

Upstream 100 bases:

>100_bases
CCGTTGCCGCGCCGGCGCGCCGTCCCGTCGAGCCGCCGATGTAATGCCCGGGAGAGAGTGCGGCTCTTCCCGTTGACCAC
TACGAAAGAAAGCAAACATC

Downstream 100 bases:

>100_bases
CGCGGCCGCGCGCCGGCCTCTGCCGAATCGGAATGCCGGCACGGCTCGCGCCCGGCGCGACGATCGGCTTCGGCCGGCGC
AGAAAGGAACCGCGGGAAAA

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 600; Mature: 599

Protein sequence:

>600_residues
MSMRTEYCGLVTEHLLGQTVSLCGWVQRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFATAEGVRNEFCVQVKGLVRNR
PEGTVNAGLKSGKIEVLCHELTVLNASVTPPFQLDDDNLSETTRLTHRVLDLRRPQMQHNLRLRYRVAIEARKYLDEQGF
IDIETPMLTKSTPEGARDYLVPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETS
FLGEQEIRDLFEDMIRHIFKTTIDVELDAKFPVMPYSEAMARFGSDKPDLRVKLEFTELTDAMKDVDFKVFSTPANTKDG
RVAALRVPKGAELTRGDIDGYTEFVRIYGAKGLAWIKVNERAKGRDGLQSPIVKNLHDASIAAILERTGAQDGDIVFFAA
DRAKVVNDSLGALRLKIGHSEFGKANGLVESGWKPLWVVDFPMFEYDDEEARYVAAHHPFTSPKDEHLEYLETDPGRCLA
KAYDMVLNGWEIGGGSVRIHREEVQSKVFRALKIGPEEAQAKFGFLLDALQYGAPPHGGIAFGLDRIVTMMAGADSIRDV
IAFPKTQRAQCLLTQAPSPVDERQLRELHIRLRQPEQPKA

Sequences:

>Translated_600_residues
MSMRTEYCGLVTEHLLGQTVSLCGWVQRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFATAEGVRNEFCVQVKGLVRNR
PEGTVNAGLKSGKIEVLCHELTVLNASVTPPFQLDDDNLSETTRLTHRVLDLRRPQMQHNLRLRYRVAIEARKYLDEQGF
IDIETPMLTKSTPEGARDYLVPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETS
FLGEQEIRDLFEDMIRHIFKTTIDVELDAKFPVMPYSEAMARFGSDKPDLRVKLEFTELTDAMKDVDFKVFSTPANTKDG
RVAALRVPKGAELTRGDIDGYTEFVRIYGAKGLAWIKVNERAKGRDGLQSPIVKNLHDASIAAILERTGAQDGDIVFFAA
DRAKVVNDSLGALRLKIGHSEFGKANGLVESGWKPLWVVDFPMFEYDDEEARYVAAHHPFTSPKDEHLEYLETDPGRCLA
KAYDMVLNGWEIGGGSVRIHREEVQSKVFRALKIGPEEAQAKFGFLLDALQYGAPPHGGIAFGLDRIVTMMAGADSIRDV
IAFPKTQRAQCLLTQAPSPVDERQLRELHIRLRQPEQPKA
>Mature_599_residues
SMRTEYCGLVTEHLLGQTVSLCGWVQRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFATAEGVRNEFCVQVKGLVRNRP
EGTVNAGLKSGKIEVLCHELTVLNASVTPPFQLDDDNLSETTRLTHRVLDLRRPQMQHNLRLRYRVAIEARKYLDEQGFI
DIETPMLTKSTPEGARDYLVPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETSF
LGEQEIRDLFEDMIRHIFKTTIDVELDAKFPVMPYSEAMARFGSDKPDLRVKLEFTELTDAMKDVDFKVFSTPANTKDGR
VAALRVPKGAELTRGDIDGYTEFVRIYGAKGLAWIKVNERAKGRDGLQSPIVKNLHDASIAAILERTGAQDGDIVFFAAD
RAKVVNDSLGALRLKIGHSEFGKANGLVESGWKPLWVVDFPMFEYDDEEARYVAAHHPFTSPKDEHLEYLETDPGRCLAK
AYDMVLNGWEIGGGSVRIHREEVQSKVFRALKIGPEEAQAKFGFLLDALQYGAPPHGGIAFGLDRIVTMMAGADSIRDVI
AFPKTQRAQCLLTQAPSPVDERQLRELHIRLRQPEQPKA

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=612, Percent_Identity=39.0522875816993, Blast_Score=420, Evalue=1e-117,
Organism=Homo sapiens, GI45439306, Length=285, Percent_Identity=29.1228070175439, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI194272210, Length=255, Percent_Identity=24.3137254901961, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI5031815, Length=255, Percent_Identity=24.3137254901961, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1788173, Length=591, Percent_Identity=58.2064297800338, Blast_Score=701, Evalue=0.0,
Organism=Escherichia coli, GI1789256, Length=297, Percent_Identity=25.9259259259259, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790571, Length=247, Percent_Identity=25.5060728744939, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI32566633, Length=604, Percent_Identity=34.9337748344371, Blast_Score=323, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI17551876, Length=262, Percent_Identity=25.5725190839695, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17535925, Length=259, Percent_Identity=23.1660231660232, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17535927, Length=279, Percent_Identity=22.9390681003584, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71994340, Length=301, Percent_Identity=22.9235880398671, Blast_Score=79, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6325153, Length=646, Percent_Identity=33.1269349845201, Blast_Score=276, Evalue=8e-75,
Organism=Saccharomyces cerevisiae, GI6323011, Length=259, Percent_Identity=29.3436293436293, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6321807, Length=249, Percent_Identity=26.9076305220884, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324256, Length=261, Percent_Identity=25.2873563218391, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320242, Length=262, Percent_Identity=25.1908396946565, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24584738, Length=607, Percent_Identity=35.7495881383855, Blast_Score=349, Evalue=4e-96,
Organism=Drosophila melanogaster, GI17136276, Length=264, Percent_Identity=29.1666666666667, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640849, Length=254, Percent_Identity=25.9842519685039, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640851, Length=254, Percent_Identity=25.9842519685039, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 67791; Mature: 67660

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMRTEYCGLVTEHLLGQTVSLCGWVQRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCHHHHHH
TAEGVRNEFCVQVKGLVRNRPEGTVNAGLKSGKIEVLCHELTVLNASVTPPFQLDDDNLS
HHHHHHHHHHHEEHHHHCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCEECCCCCH
ETTRLTHRVLDLRRPQMQHNLRLRYRVAIEARKYLDEQGFIDIETPMLTKSTPEGARDYL
HHHHHHHHHHHHCCCHHHCCCEEEEEEEEHHHHHCCCCCCEEECCCCCCCCCCCCCHHCC
VPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETS
CCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCHH
FLGEQEIRDLFEDMIRHIFKTTIDVELDAKFPVMPYSEAMARFGSDKPDLRVKLEFTELT
HCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEEEHHHHH
DAMKDVDFKVFSTPANTKDGRVAALRVPKGAELTRGDIDGYTEFVRIYGAKGLAWIKVNE
HHHHCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECC
RAKGRDGLQSPIVKNLHDASIAAILERTGAQDGDIVFFAADRAKVVNDSLGALRLKIGHS
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCCCCEEEEEECCC
EFGKANGLVESGWKPLWVVDFPMFEYDDEEARYVAAHHPFTSPKDEHLEYLETDPGRCLA
CCCCCCCCHHCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCCHHHH
KAYDMVLNGWEIGGGSVRIHREEVQSKVFRALKIGPEEAQAKFGFLLDALQYGAPPHGGI
HHHHHHHCCEEECCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCH
AFGLDRIVTMMAGADSIRDVIAFPKTQRAQCLLTQAPSPVDERQLRELHIRLRQPEQPKA
HHHHHHHHHHHHCHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SMRTEYCGLVTEHLLGQTVSLCGWVQRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCHHHHHH
TAEGVRNEFCVQVKGLVRNRPEGTVNAGLKSGKIEVLCHELTVLNASVTPPFQLDDDNLS
HHHHHHHHHHHEEHHHHCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCEECCCCCH
ETTRLTHRVLDLRRPQMQHNLRLRYRVAIEARKYLDEQGFIDIETPMLTKSTPEGARDYL
HHHHHHHHHHHHCCCHHHCCCEEEEEEEEHHHHHCCCCCCEEECCCCCCCCCCCCCHHCC
VPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETS
CCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCHH
FLGEQEIRDLFEDMIRHIFKTTIDVELDAKFPVMPYSEAMARFGSDKPDLRVKLEFTELT
HCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEEEHHHHH
DAMKDVDFKVFSTPANTKDGRVAALRVPKGAELTRGDIDGYTEFVRIYGAKGLAWIKVNE
HHHHCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECC
RAKGRDGLQSPIVKNLHDASIAAILERTGAQDGDIVFFAADRAKVVNDSLGALRLKIGHS
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCCCCEEEEEECCC
EFGKANGLVESGWKPLWVVDFPMFEYDDEEARYVAAHHPFTSPKDEHLEYLETDPGRCLA
CCCCCCCCHHCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCCHHHH
KAYDMVLNGWEIGGGSVRIHREEVQSKVFRALKIGPEEAQAKFGFLLDALQYGAPPHGGI
HHHHHHHCCEEECCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCH
AFGLDRIVTMMAGADSIRDVIAFPKTQRAQCLLTQAPSPVDERQLRELHIRLRQPEQPKA
HHHHHHHHHHHHCHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA