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The map label for this gene is hemN-2 [H]

Identifier: 83720202

GI number: 83720202

Start: 2017928

End: 2019373

Strand: Direct

Name: hemN-2 [H]

Synonym: BTH_I1800

Alternate gene names: 83720202

Gene position: 2017928-2019373 (Clockwise)

Preceding gene: 83721567

Following gene: 83720430

Centisome position: 52.98

GC content: 65.77

Gene sequence:

>1446_bases
ATGACAACGCATTCGAACGACGGCGCGGATACGACCGCGCCCACTCCCCACCACGACGTTTCCGCATTCGCGGACGTTCA
GATATCCGAAGCGCTGATCCGGCGCTTCGACCGGCAAGGACCGCGCTACACGTCGTATCCGACGGCCGACCGGTTTTCCG
ACGCATTCGACGAGCGCGCGTACCGCGAGCATCTGTCGCGCCGCGCGTCGGCCGAGCGCAACCCGCCGTTGTCGGTCTAT
CTGCATCTGCCGTTTTGCGAGTCGCTCTGCTACTTCTGCGCGTGCAACAAGATCATCACGCAGGATCACACCCGAACGAG
TGCGTACGTAGACTACCTGATCCGCGAAATGGAGCTCGTCGCACCCGATCTCGGCCGCGACCGCGTGACGACGCAGCTGC
ATCTGGGCGGAGGATCGCCGACGTTCTTCGCGATCGACGAACTCGCGCGCCTGATGCGCGCGCTGCGCGATCACTTCGAT
TTCGCGCCGCACGCGGAGCTTGGCGTGGAGATCGATCCGCGCACGGTCGACGAGCGCACGCTGCAGTCGCTCGCGGCGCT
CGGCTTCAACCGGACGAGCTTCGGCGTTCAGGATTTCGATCCGGCGGTGCAGGAGGCGGTGCACCGGGTCCAGCCGCTGC
CGATGGTCGAGCGCGCGCTCGCGGCGAGTCGCGCGGCCGGGTTCGAATCGGTCAATATCGATCTGATCTACGGGCTGCCG
CGACAAACGCCGGCGAGCTTCTCGCGTACGCTCGACGAGGTGATCCGGCTGTCGCCCGACCGCATCGCGGTCTACAACTA
TGCGCATCTGCCGAGCCGCTTCAAGGCGCAGCGCCTGATCGTCGAATCGGAGCTGCCGGCCGCCGAAGACCGGCTGCGCA
TCTTCATCGAATCGACGCGGCGGTTGCTCGACGCCGGATACGTGTACATCGGGCTCGACCACTTCGCGAAGCCGAACGAC
GAGCTCAGCAACGCATTGCGCGAGCGCAGCCTGCACCGCAATTTCCAGGGCTACACGACGCAGGCCGAATGCGACCTCGT
CGGCTTCGGCGTATCGGCGATCGGCAAGGTCGGCGCGTCGTACAGCCAGTCGACGCGCTCGCTGAAGACCTATTATCGCC
AGCTCGACGCCGGACGCCTGCCGATCGAGCGCGGCTTCGCGCTGAGCGCCGACGATCTGCTGCGCCGCGAGGTCATCATG
ACAGTGATGTGCAGCACCCCCGTCGATTTCGCGGAGATCGGCCGCAGGCACGGCGTCGATTTCGTGCGGCATTTCGCGCA
CGAGCTCGCGCAGCTCGAGCCGTATCGCGACGCCGGGCTGCTCACGATAGACGCGGAGCGCATCGCCATTACGCCGAAGG
GGCGCATGTTCGTGCGCGCGATCGGCATGGTGTTCGACGCGTATCTCGGCCGGCCTGCCTCGGCGTCCTATTCGAAGTTG
ATCTAG

Upstream 100 bases:

>100_bases
CAATGTCGGAGGTTGATTTGCATCAAGTCCGCCCGAGCCGCGCGACCGACAATGGAACGCCGGCGTTTCGCGCGGCATGC
CAGGGTACAAGCAGATGGAC

Downstream 100 bases:

>100_bases
AAGGTGGCGTGATGAAGGAAAGCAAGATTCCGGTCCAGGACTTTCTCGCGCGGTTGCCGCTCTTCAGCGTGCTGTCGCGC
GGCGAGCTCGACAATCTCGC

Product: coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MTTHSNDGADTTAPTPHHDVSAFADVQISEALIRRFDRQGPRYTSYPTADRFSDAFDERAYREHLSRRASAERNPPLSVY
LHLPFCESLCYFCACNKIITQDHTRTSAYVDYLIREMELVAPDLGRDRVTTQLHLGGGSPTFFAIDELARLMRALRDHFD
FAPHAELGVEIDPRTVDERTLQSLAALGFNRTSFGVQDFDPAVQEAVHRVQPLPMVERALAASRAAGFESVNIDLIYGLP
RQTPASFSRTLDEVIRLSPDRIAVYNYAHLPSRFKAQRLIVESELPAAEDRLRIFIESTRRLLDAGYVYIGLDHFAKPND
ELSNALRERSLHRNFQGYTTQAECDLVGFGVSAIGKVGASYSQSTRSLKTYYRQLDAGRLPIERGFALSADDLLRREVIM
TVMCSTPVDFAEIGRRHGVDFVRHFAHELAQLEPYRDAGLLTIDAERIAITPKGRMFVRAIGMVFDAYLGRPASASYSKL
I

Sequences:

>Translated_481_residues
MTTHSNDGADTTAPTPHHDVSAFADVQISEALIRRFDRQGPRYTSYPTADRFSDAFDERAYREHLSRRASAERNPPLSVY
LHLPFCESLCYFCACNKIITQDHTRTSAYVDYLIREMELVAPDLGRDRVTTQLHLGGGSPTFFAIDELARLMRALRDHFD
FAPHAELGVEIDPRTVDERTLQSLAALGFNRTSFGVQDFDPAVQEAVHRVQPLPMVERALAASRAAGFESVNIDLIYGLP
RQTPASFSRTLDEVIRLSPDRIAVYNYAHLPSRFKAQRLIVESELPAAEDRLRIFIESTRRLLDAGYVYIGLDHFAKPND
ELSNALRERSLHRNFQGYTTQAECDLVGFGVSAIGKVGASYSQSTRSLKTYYRQLDAGRLPIERGFALSADDLLRREVIM
TVMCSTPVDFAEIGRRHGVDFVRHFAHELAQLEPYRDAGLLTIDAERIAITPKGRMFVRAIGMVFDAYLGRPASASYSKL
I
>Mature_480_residues
TTHSNDGADTTAPTPHHDVSAFADVQISEALIRRFDRQGPRYTSYPTADRFSDAFDERAYREHLSRRASAERNPPLSVYL
HLPFCESLCYFCACNKIITQDHTRTSAYVDYLIREMELVAPDLGRDRVTTQLHLGGGSPTFFAIDELARLMRALRDHFDF
APHAELGVEIDPRTVDERTLQSLAALGFNRTSFGVQDFDPAVQEAVHRVQPLPMVERALAASRAAGFESVNIDLIYGLPR
QTPASFSRTLDEVIRLSPDRIAVYNYAHLPSRFKAQRLIVESELPAAEDRLRIFIESTRRLLDAGYVYIGLDHFAKPNDE
LSNALRERSLHRNFQGYTTQAECDLVGFGVSAIGKVGASYSQSTRSLKTYYRQLDAGRLPIERGFALSADDLLRREVIMT
VMCSTPVDFAEIGRRHGVDFVRHFAHELAQLEPYRDAGLLTIDAERIAITPKGRMFVRAIGMVFDAYLGRPASASYSKLI

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=189, Percent_Identity=26.4550264550265, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87082341, Length=452, Percent_Identity=46.6814159292035, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1789325, Length=297, Percent_Identity=27.9461279461279, Blast_Score=110, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004558
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 54128; Mature: 53997

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTHSNDGADTTAPTPHHDVSAFADVQISEALIRRFDRQGPRYTSYPTADRFSDAFDERA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
YREHLSRRASAERNPPLSVYLHLPFCESLCYFCACNKIITQDHTRTSAYVDYLIREMELV
HHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
APDLGRDRVTTQLHLGGGSPTFFAIDELARLMRALRDHFDFAPHAELGVEIDPRTVDERT
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHH
LQSLAALGFNRTSFGVQDFDPAVQEAVHRVQPLPMVERALAASRAAGFESVNIDLIYGLP
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCC
RQTPASFSRTLDEVIRLSPDRIAVYNYAHLPSRFKAQRLIVESELPAAEDRLRIFIESTR
CCCHHHHHHHHHHHHHCCCCCEEEEEEHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RLLDAGYVYIGLDHFAKPNDELSNALRERSLHRNFQGYTTQAECDLVGFGVSAIGKVGAS
HHHHCCEEEEEHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHCCH
YSQSTRSLKTYYRQLDAGRLPIERGFALSADDLLRREVIMTVMCSTPVDFAEIGRRHGVD
HHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHH
FVRHFAHELAQLEPYRDAGLLTIDAERIAITPKGRMFVRAIGMVFDAYLGRPASASYSKL
HHHHHHHHHHHCCCCCCCCEEEEECCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHC
I
C
>Mature Secondary Structure 
TTHSNDGADTTAPTPHHDVSAFADVQISEALIRRFDRQGPRYTSYPTADRFSDAFDERA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
YREHLSRRASAERNPPLSVYLHLPFCESLCYFCACNKIITQDHTRTSAYVDYLIREMELV
HHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
APDLGRDRVTTQLHLGGGSPTFFAIDELARLMRALRDHFDFAPHAELGVEIDPRTVDERT
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHH
LQSLAALGFNRTSFGVQDFDPAVQEAVHRVQPLPMVERALAASRAAGFESVNIDLIYGLP
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCC
RQTPASFSRTLDEVIRLSPDRIAVYNYAHLPSRFKAQRLIVESELPAAEDRLRIFIESTR
CCCHHHHHHHHHHHHHCCCCCEEEEEEHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RLLDAGYVYIGLDHFAKPNDELSNALRERSLHRNFQGYTTQAECDLVGFGVSAIGKVGAS
HHHHCCEEEEEHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHCCH
YSQSTRSLKTYYRQLDAGRLPIERGFALSADDLLRREVIMTVMCSTPVDFAEIGRRHGVD
HHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHH
FVRHFAHELAQLEPYRDAGLLTIDAERIAITPKGRMFVRAIGMVFDAYLGRPASASYSKL
HHHHHHHHHHHCCCCCCCCEEEEECCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9396835 [H]