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The map label for this gene is dnaX [H]

Identifier: 83720172

GI number: 83720172

Start: 2495220

End: 2497658

Strand: Direct

Name: dnaX [H]

Synonym: BTH_I2219

Alternate gene names: 83720172

Gene position: 2495220-2497658 (Clockwise)

Preceding gene: 83720043

Following gene: 83719436

Centisome position: 65.51

GC content: 72.82

Gene sequence:

>2439_bases
ATGACCTATCAAGTTCTCGCACGCAAGTGGCGTCCGAAGGATTTCGCTTCGCTCGTCGGCCAGGAGCACGTCGTCAGGGC
GCTCACGCACGCGCTCGACGGCGGGCGTTTGCATCACGCCTATCTATTCACGGGCACGCGCGGCGTCGGCAAGACAACGC
TGTCGCGCATCTTCGCGAAGGCGCTCAATTGCGAGACGGGCGTCACGTCGCAGCCGTGCGGCGTGTGCCGCGCGTGCCGC
GAAATCGATGAAGGGCGCTTCGTCGACTATGTCGAAATGGACGCGGCGAGCAATCGCGGCGTCGATGAAATGGCCGCGCT
GCTCGAGCGCGCGGTGTACGCGCCCGTCGATGCGCGCTTCAAGGTCTACATGATCGACGAAGTGCACATGCTGACGAACC
ACGCGTTCAACGCGATGCTCAAGACGCTCGAGGAGCCGCCGCCGCACGTCAAGTTCATCCTCGCGACCACCGACCCGCAG
AAGATTCCCGTCACCGTGCTGTCGCGCTGCCTGCAGTTCAATCTGAAGCAGATGCCGGCCGGGCACATCGTGTCGCACCT
CGAGCGGATTCTCGGCGAAGAGCGGATCGCGTTCGAGCCGCAGGCGCTGCGCCTTCTCGCGCGCGCGGCGCAGGGCAGCA
TGCGCGATGCGCTGTCGCTGACCGATCAGGCGATCGCGTATTCGGCGAACGAAGTGACGGAAACCGCCGTGTCCGGCATG
CTCGGCACGCTCGACCAGACCTACATGGTGCGGCTCCTCGACGCGCTCGCCGCGGCCGACGGCCCGCAGATTCTCGCCGT
CGCCGATGAGATGGCGCTGCGCAGCCTGTCGTTCTCGGCCGCGCTGCAGGATCTCGCGAGCCTGCTGCACCGGATCGCGT
GGGCGCAGTTCGCGCCGGCGTCGGTGCTCGACGAATGGCCGGAAGCGGCCGATCTGCGTCGCTTCGCCGAACTGCTGAGC
CCGGAGCAGGTGCAGCTCTATTATCAGATCGCGACGGTCGGGCGCGGCGAGCTCGGCCTCGCGCCCGACGAATACGCGGG
CTTCACGATGACGCTGCTGCGAATGCTGGCGTTCGAGCCGGCGACGACGGGCGGCGGCGCGCCGGGCGGCGGGGTGCCCG
CTCAGGTGTCCGGCGCCGCGCCGAAGCCGGGGGCGCGCACCGCGATCGCGGTCGGCGCGTCGGCGGCGCCCGCGGTTGCG
GCGGCGCCAACGCCGAAGGCGGCCGTCGCGCGTGCGGCAACGCGCGCCGAGCCGCCGCCGTCCCAAGCGGAGCCGGCGAC
GACCGAGACGGTCGGCGGCGCTTCCGCGGACGTTCGCGCGCCGGCCGACGCCGGCCCGGGCGAGCGCGACGCCGCGCCGT
GCGTCGAATCAGTCGCGCCGCCGAGCACGCGGGAGGATGCCGCGCGTGAATCCGCGGCGCGAGCGGCCGTGTCATTCGAA
TCGACGTCCGTCGCCGAGCGCGACGCGATCACGCCGGCCGCCGCATCGACCGGGGAGGTCGCCGCGATGCCTGCGTCCGT
CGCGACCGAATCACGCGCGCCGGCGCCCACCGCCGACGCATCCGCGTCGCGCGCGACCGGCGCGGCCGCCGCGCTCGACG
TGCTGCGCAACGCGGGCATGCGCGTGTCGTCCGATCGCGGCCGCAACGCCGGCGCCGCGAGGCCGGCCGCGCCAGCCGCC
GCGCCCGCCGCGCCCGCCGCGCCCACCGCGAAGGCCGCGCCGCGCGTGCCGGTGCCCGTGCCGACGCCGCGCGGCCGCGC
ATCGGGCAGCGATGCGCGGCCGAACGGCGCGGCGCGCGCCGAAGCGAGATCCGAGTCTCGCGGCGCGCCGCCGCCGTGGG
AGGACATCCCGCCCGACGATTACGTGCCGTTGTCGATGGACGACGGTTTCATCCCGCCCGACGACGGTTTCGTCCCGGTG
TTCGACAGCGGCCCCGACGACGTCCGCGTCGCGCCGAAGCCGGCTCCCGCGCCGTCCGTCGACACACGCCCGCTGCCGGA
GCCGATCCCGCTCGACACGATCGGCTATGCCGGCGAGTGGGCGACGCTCGCGGCGAGCCTGCCACTCAAGGGAGTCGCGT
ACCAGCTCGCGTTCAACAGCGAGCTGACGTCGGCCGACGGCGGCGCGCTCAAGCTTGCCGTGCCGGTTCCGCAATACGCG
GACGCCGCGCAGGTCGCCAAGCTGAAAGCGGCGCTTGCGGACGCGCTCGGCAAGCCGGTGGACGTGATGGTCGAAGTCGG
GCCGGCGCGCCGCACCGCGGCGGCGCTCGCCGCCGCCGAGCGCGCGAAGCGGCAGCGCGAGGCCGAGCAGGAGATGAATG
CCGACCCGTTCGTCCAGCAGTTGCTGCGCGAATTCGGCGCGAGCATCGTCGAAGGCTCGATTCGGCCCGTCGGCCCGGAA
GCGGGCGCCGCGGACGGCGCCTCGCCGACGCTGCACTGA

Upstream 100 bases:

>100_bases
GGTTCCGCTTTTTCCGGGCTTCTCCGATCGGCTCGATATGCGCGTGCTTCGCGGCGTTCAACCTGTCGGCGTGGCTCAGC
GTTGCTGATACAATTTCCCG

Downstream 100 bases:

>100_bases
CGCGAGCCGGGCGCTGCGCGCGCCCGGTTTCCATATTCGCGCGCGGGCGCTAAGATCGCGCCCGTTCGCAATCGATTACG
AAGGAGCAAGTCCATGATGA

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 812; Mature: 811

Protein sequence:

>812_residues
MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR
EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ
KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAVSGM
LGTLDQTYMVRLLDALAAADGPQILAVADEMALRSLSFSAALQDLASLLHRIAWAQFAPASVLDEWPEAADLRRFAELLS
PEQVQLYYQIATVGRGELGLAPDEYAGFTMTLLRMLAFEPATTGGGAPGGGVPAQVSGAAPKPGARTAIAVGASAAPAVA
AAPTPKAAVARAATRAEPPPSQAEPATTETVGGASADVRAPADAGPGERDAAPCVESVAPPSTREDAARESAARAAVSFE
STSVAERDAITPAAASTGEVAAMPASVATESRAPAPTADASASRATGAAAALDVLRNAGMRVSSDRGRNAGAARPAAPAA
APAAPAAPTAKAAPRVPVPVPTPRGRASGSDARPNGAARAEARSESRGAPPPWEDIPPDDYVPLSMDDGFIPPDDGFVPV
FDSGPDDVRVAPKPAPAPSVDTRPLPEPIPLDTIGYAGEWATLAASLPLKGVAYQLAFNSELTSADGGALKLAVPVPQYA
DAAQVAKLKAALADALGKPVDVMVEVGPARRTAAALAAAERAKRQREAEQEMNADPFVQQLLREFGASIVEGSIRPVGPE
AGAADGASPTLH

Sequences:

>Translated_812_residues
MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR
EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ
KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAVSGM
LGTLDQTYMVRLLDALAAADGPQILAVADEMALRSLSFSAALQDLASLLHRIAWAQFAPASVLDEWPEAADLRRFAELLS
PEQVQLYYQIATVGRGELGLAPDEYAGFTMTLLRMLAFEPATTGGGAPGGGVPAQVSGAAPKPGARTAIAVGASAAPAVA
AAPTPKAAVARAATRAEPPPSQAEPATTETVGGASADVRAPADAGPGERDAAPCVESVAPPSTREDAARESAARAAVSFE
STSVAERDAITPAAASTGEVAAMPASVATESRAPAPTADASASRATGAAAALDVLRNAGMRVSSDRGRNAGAARPAAPAA
APAAPAAPTAKAAPRVPVPVPTPRGRASGSDARPNGAARAEARSESRGAPPPWEDIPPDDYVPLSMDDGFIPPDDGFVPV
FDSGPDDVRVAPKPAPAPSVDTRPLPEPIPLDTIGYAGEWATLAASLPLKGVAYQLAFNSELTSADGGALKLAVPVPQYA
DAAQVAKLKAALADALGKPVDVMVEVGPARRTAAALAAAERAKRQREAEQEMNADPFVQQLLREFGASIVEGSIRPVGPE
AGAADGASPTLH
>Mature_811_residues
TYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACRE
IDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQK
IPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAVSGML
GTLDQTYMVRLLDALAAADGPQILAVADEMALRSLSFSAALQDLASLLHRIAWAQFAPASVLDEWPEAADLRRFAELLSP
EQVQLYYQIATVGRGELGLAPDEYAGFTMTLLRMLAFEPATTGGGAPGGGVPAQVSGAAPKPGARTAIAVGASAAPAVAA
APTPKAAVARAATRAEPPPSQAEPATTETVGGASADVRAPADAGPGERDAAPCVESVAPPSTREDAARESAARAAVSFES
TSVAERDAITPAAASTGEVAAMPASVATESRAPAPTADASASRATGAAAALDVLRNAGMRVSSDRGRNAGAARPAAPAAA
PAAPAAPTAKAAPRVPVPVPTPRGRASGSDARPNGAARAEARSESRGAPPPWEDIPPDDYVPLSMDDGFIPPDDGFVPVF
DSGPDDVRVAPKPAPAPSVDTRPLPEPIPLDTIGYAGEWATLAASLPLKGVAYQLAFNSELTSADGGALKLAVPVPQYAD
AAQVAKLKAALADALGKPVDVMVEVGPARRTAAALAAAERAKRQREAEQEMNADPFVQQLLREFGASIVEGSIRPVGPEA
GAADGASPTLH

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=327, Percent_Identity=23.8532110091743, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI194306571, Length=330, Percent_Identity=23.6363636363636, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI194306567, Length=330, Percent_Identity=23.6363636363636, Blast_Score=73, Evalue=8e-13,
Organism=Escherichia coli, GI1786676, Length=361, Percent_Identity=57.617728531856, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI1787341, Length=183, Percent_Identity=31.1475409836066, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787119, Length=230, Percent_Identity=27.8260869565217, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71986063, Length=300, Percent_Identity=24, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17554730, Length=276, Percent_Identity=25.7246376811594, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324039, Length=218, Percent_Identity=27.0642201834862, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI18859927, Length=317, Percent_Identity=21.7665615141956, Blast_Score=73, Evalue=8e-13,
Organism=Drosophila melanogaster, GI19921076, Length=304, Percent_Identity=23.3552631578947, Blast_Score=66, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 84347; Mature: 84216

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAK
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHH
ALNCETGVTSQPCGVCRACREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARF
HHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCE
KVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPA
EEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCH
GHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAVSGM
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LGTLDQTYMVRLLDALAAADGPQILAVADEMALRSLSFSAALQDLASLLHRIAWAQFAPA
HHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SVLDEWPEAADLRRFAELLSPEQVQLYYQIATVGRGELGLAPDEYAGFTMTLLRMLAFEP
HHHHHCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCHHHCHHHHHHHHHHHCCC
ATTGGGAPGGGVPAQVSGAAPKPGARTAIAVGASAAPAVAAAPTPKAAVARAATRAEPPP
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCC
SQAEPATTETVGGASADVRAPADAGPGERDAAPCVESVAPPSTREDAARESAARAAVSFE
CCCCCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
STSVAERDAITPAAASTGEVAAMPASVATESRAPAPTADASASRATGAAAALDVLRNAGM
CHHHHHHHCCCCCCCCCCCEEECCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
RVSSDRGRNAGAARPAAPAAAPAAPAAPTAKAAPRVPVPVPTPRGRASGSDARPNGAARA
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
EARSESRGAPPPWEDIPPDDYVPLSMDDGFIPPDDGFVPVFDSGPDDVRVAPKPAPAPSV
HHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCEECCCCCCCCCC
DTRPLPEPIPLDTIGYAGEWATLAASLPLKGVAYQLAFNSELTSADGGALKLAVPVPQYA
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCC
DAAQVAKLKAALADALGKPVDVMVEVGPARRTAAALAAAERAKRQREAEQEMNADPFVQQ
CHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LLREFGASIVEGSIRPVGPEAGAADGASPTLH
HHHHHCHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAK
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHH
ALNCETGVTSQPCGVCRACREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARF
HHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCE
KVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPA
EEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCH
GHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAVSGM
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LGTLDQTYMVRLLDALAAADGPQILAVADEMALRSLSFSAALQDLASLLHRIAWAQFAPA
HHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SVLDEWPEAADLRRFAELLSPEQVQLYYQIATVGRGELGLAPDEYAGFTMTLLRMLAFEP
HHHHHCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCHHHCHHHHHHHHHHHCCC
ATTGGGAPGGGVPAQVSGAAPKPGARTAIAVGASAAPAVAAAPTPKAAVARAATRAEPPP
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCC
SQAEPATTETVGGASADVRAPADAGPGERDAAPCVESVAPPSTREDAARESAARAAVSFE
CCCCCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
STSVAERDAITPAAASTGEVAAMPASVATESRAPAPTADASASRATGAAAALDVLRNAGM
CHHHHHHHCCCCCCCCCCCEEECCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
RVSSDRGRNAGAARPAAPAAAPAAPAAPTAKAAPRVPVPVPTPRGRASGSDARPNGAARA
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
EARSESRGAPPPWEDIPPDDYVPLSMDDGFIPPDDGFVPVFDSGPDDVRVAPKPAPAPSV
HHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCEECCCCCCCCCC
DTRPLPEPIPLDTIGYAGEWATLAASLPLKGVAYQLAFNSELTSADGGALKLAVPVPQYA
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCC
DAAQVAKLKAALADALGKPVDVMVEVGPARRTAAALAAAERAKRQREAEQEMNADPFVQQ
CHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LLREFGASIVEGSIRPVGPEAGAADGASPTLH
HHHHHCHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]