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The map label for this gene is pyrG [H]

Identifier: 83720006

GI number: 83720006

Start: 2139918

End: 2141579

Strand: Direct

Name: pyrG [H]

Synonym: BTH_I1892

Alternate gene names: 83720006

Gene position: 2139918-2141579 (Clockwise)

Preceding gene: 83719013

Following gene: 83720532

Centisome position: 56.18

GC content: 64.02

Gene sequence:

>1662_bases
ATGACCAAATATGTTTTCGTCACCGGCGGCGTAGTTTCCTCCCTCGGCAAGGGCATTGCCGCCGCCTCTCTCGCCGCGAT
CCTCGAATCGCGCGGTCTCAAAGTCACCCTCCTCAAACTCGATCCTTACATCAACGTCGACCCCGGCACGATGAGCCCGT
TTCAGCACGGCGAAGTGTTCGTGACGGAAGACGGCGCGGAGACGGATCTCGACCTCGGCCACTATGAGCGCTTCATCAGC
ACGAAGATGCGCAAGGCCAACAACTTCACGACCGGTCAGATCTACGAATCGGTGATCCGCAAGGAGCGTCGCGGCGATTA
CCTCGGCAAGACCGTCCAGGTGATTCCGCACATCACGAACGAGATCCAGGCGTTCATCGAGCGCGGCGCGGCGTCGGCCA
CCTGCGGCGAGCCGGATGTGGCCATCGTCGAGATCGGCGGCACGGTGGGCGACATCGAGTCGCTGCCGTTCCTCGAGGCG
GCGCGCCAGATGAGCCTGCGCCTCGGCCGCAACAGCGCATGCTTCGTTCACCTGACGCTCGTGCCGTTCATCGCGACGGC
GGGCGAGCTGAAGACGAAGCCGACCCAGCACAGCGTGCAGAAGCTGCGCGAGATCGGCATTTCGCCGCACGTGCTGCTCT
GCCGTGCCGATCGCCCGATTCCCGACGACGAATCGAAGAAGATCTCGCTCTTCTCGAACGTGCCGGAAGACGCGGTGATC
TCGGTGTGGGACGTCGACAGCATCTATAAGATTCCGCAGATGCTGCACGACCAGGGGCTCGACCGCCTCATCTGCGAGGA
GTTGCGCCTCGATCCGCAGCCGGCCGACCTGCGCATGTGGTCGGAGCTCGTCGAGAAGCTTCAGAATCCGAAGCACGAGG
TGACGATCGGGATGGTCGGCAAGTACGTCGACCTGACGGAGTCGTACAAGTCGCTGATCGAAGCGCTGCGTCATGCGTCG
ATCCACACGTCGACGAAGGTCAACATCGAGTACATCGATTCGGAAGAGCTCGAGGCGAACGGCACCGCGAGCCTCGCTCA
TCTCGACGCCGTGCTCGTGCCGGGCGGCTTCGGCCGGCGCGGCACCGAAGGCAAGATCGCGGCCGTGCGCTATGCGCGCG
AAGCGAAGGTGCCGTATCTCGGCATCTGCCTCGGCATGCAACTCGCCGTCATCGAATTCGCGCGCGACGTCGTCGGCCTC
AAGCAGGCGAACAGCACCGAGTTCGATCCGAACACGCCGGAGCGCGTCGTCGCGCTGATCACCGAGTGGTACGACCGCGA
GGGCAAGGTCGAGAAGCGCACCGAGGATTCCGATCTCGGCGGCACGATGCGGCTCGGCTCGCAGCGCTGCCCGATCAAGC
CGGGCACGCTCGCCGAAGCGATTTACGGCAAGGACGTGAACGAGCGCCACCGTCATCGTTACGAAGTCAACAACCGCTTC
GTGCCGCAACTCGAAGCGGGCGGCCTCGTGATCAGCGCGCGCACGCCGAGCGAAGATCTGCCGGAAATGATGGAGCTGCC
GCGCGCGATGCACCCGTGGTTCGTCGGCGTTCAGTTCCACCCGGAATTCACGTCGACGCCGCGTGACGGCCATCCGCTCT
TCAAGTCGTTCGTTCAAGCCGCGATCGCGTGTCAGCAGGCGCGCGCCGGAGCGAAAGCATGA

Upstream 100 bases:

>100_bases
CGAGCGCGGACAGTAACGGGAAGGGGCGCGATCGCGCGTCGATTGCTGAGTGACGCGCGGCCTTTACGGTATAATCCGTT
TTTCCCGCGAGCATCCAGCG

Downstream 100 bases:

>100_bases
ATCTCGCCGGATTCGAAGTCGGGCTCGACAAGCCGTTCTTCCTGATCGCCGGCACCTGCGTCGTCGAATCGGAGCAGATG
ACGATCGACACCGCAGGCCG

Product: CTP synthetase

Products: NA

Alternate protein names: CTP synthetase; UTP--ammonia ligase [H]

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFIS
TKMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITNEIQAFIERGAASATCGEPDVAIVEIGGTVGDIESLPFLEA
ARQMSLRLGRNSACFVHLTLVPFIATAGELKTKPTQHSVQKLREIGISPHVLLCRADRPIPDDESKKISLFSNVPEDAVI
SVWDVDSIYKIPQMLHDQGLDRLICEELRLDPQPADLRMWSELVEKLQNPKHEVTIGMVGKYVDLTESYKSLIEALRHAS
IHTSTKVNIEYIDSEELEANGTASLAHLDAVLVPGGFGRRGTEGKIAAVRYAREAKVPYLGICLGMQLAVIEFARDVVGL
KQANSTEFDPNTPERVVALITEWYDREGKVEKRTEDSDLGGTMRLGSQRCPIKPGTLAEAIYGKDVNERHRHRYEVNNRF
VPQLEAGGLVISARTPSEDLPEMMELPRAMHPWFVGVQFHPEFTSTPRDGHPLFKSFVQAAIACQQARAGAKA

Sequences:

>Translated_553_residues
MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFIS
TKMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITNEIQAFIERGAASATCGEPDVAIVEIGGTVGDIESLPFLEA
ARQMSLRLGRNSACFVHLTLVPFIATAGELKTKPTQHSVQKLREIGISPHVLLCRADRPIPDDESKKISLFSNVPEDAVI
SVWDVDSIYKIPQMLHDQGLDRLICEELRLDPQPADLRMWSELVEKLQNPKHEVTIGMVGKYVDLTESYKSLIEALRHAS
IHTSTKVNIEYIDSEELEANGTASLAHLDAVLVPGGFGRRGTEGKIAAVRYAREAKVPYLGICLGMQLAVIEFARDVVGL
KQANSTEFDPNTPERVVALITEWYDREGKVEKRTEDSDLGGTMRLGSQRCPIKPGTLAEAIYGKDVNERHRHRYEVNNRF
VPQLEAGGLVISARTPSEDLPEMMELPRAMHPWFVGVQFHPEFTSTPRDGHPLFKSFVQAAIACQQARAGAKA
>Mature_552_residues
TKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFIST
KMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITNEIQAFIERGAASATCGEPDVAIVEIGGTVGDIESLPFLEAA
RQMSLRLGRNSACFVHLTLVPFIATAGELKTKPTQHSVQKLREIGISPHVLLCRADRPIPDDESKKISLFSNVPEDAVIS
VWDVDSIYKIPQMLHDQGLDRLICEELRLDPQPADLRMWSELVEKLQNPKHEVTIGMVGKYVDLTESYKSLIEALRHASI
HTSTKVNIEYIDSEELEANGTASLAHLDAVLVPGGFGRRGTEGKIAAVRYAREAKVPYLGICLGMQLAVIEFARDVVGLK
QANSTEFDPNTPERVVALITEWYDREGKVEKRTEDSDLGGTMRLGSQRCPIKPGTLAEAIYGKDVNERHRHRYEVNNRFV
PQLEAGGLVISARTPSEDLPEMMELPRAMHPWFVGVQFHPEFTSTPRDGHPLFKSFVQAAIACQQARAGAKA

Specific function: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen [H]

COG id: COG0504

COG function: function code F; CTP synthase (UTP-ammonia lyase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI28559085, Length=559, Percent_Identity=45.2593917710197, Blast_Score=490, Evalue=1e-138,
Organism=Homo sapiens, GI28559083, Length=559, Percent_Identity=45.2593917710197, Blast_Score=490, Evalue=1e-138,
Organism=Homo sapiens, GI221316689, Length=559, Percent_Identity=45.2593917710197, Blast_Score=490, Evalue=1e-138,
Organism=Homo sapiens, GI148491070, Length=561, Percent_Identity=45.8110516934046, Blast_Score=486, Evalue=1e-137,
Organism=Escherichia coli, GI1789142, Length=549, Percent_Identity=61.9307832422586, Blast_Score=679, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25148299, Length=609, Percent_Identity=40.0656814449918, Blast_Score=423, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6319432, Length=575, Percent_Identity=41.7391304347826, Blast_Score=451, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6322563, Length=573, Percent_Identity=41.8848167539267, Blast_Score=445, Evalue=1e-125,
Organism=Drosophila melanogaster, GI24664469, Length=560, Percent_Identity=45.1785714285714, Blast_Score=483, Evalue=1e-136,
Organism=Drosophila melanogaster, GI21357815, Length=505, Percent_Identity=43.7623762376238, Blast_Score=410, Evalue=1e-114,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004468
- InterPro:   IPR017456
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF06418 CTP_synth_N; PF00117 GATase [H]

EC number: =6.3.4.2 [H]

Molecular weight: Translated: 61096; Mature: 60964

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVF
CCEEEEEECHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCEEECCCCCCCCCCCCEEE
VTEDGAETDLDLGHYERFISTKMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITN
EECCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHCCHHHHHHHHHH
EIQAFIERGAASATCGEPDVAIVEIGGTVGDIESLPFLEAARQMSLRLGRNSACFVHLTL
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEH
VPFIATAGELKTKPTQHSVQKLREIGISPHVLLCRADRPIPDDESKKISLFSNVPEDAVI
HHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCEE
SVWDVDSIYKIPQMLHDQGLDRLICEELRLDPQPADLRMWSELVEKLQNPKHEVTIGMVG
EEECCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECC
KYVDLTESYKSLIEALRHASIHTSTKVNIEYIDSEELEANGTASLAHLDAVLVPGGFGRR
CHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHEEEEEECCCCCCC
GTEGKIAAVRYAREAKVPYLGICLGMQLAVIEFARDVVGLKQANSTEFDPNTPERVVALI
CCCCCEEEEEHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
TEWYDREGKVEKRTEDSDLGGTMRLGSQRCPIKPGTLAEAIYGKDVNERHRHRYEVNNRF
HHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCC
VPQLEAGGLVISARTPSEDLPEMMELPRAMHPWFVGVQFHPEFTSTPRDGHPLFKSFVQA
CCEECCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
AIACQQARAGAKA
HHHHHHHHCCCCC
>Mature Secondary Structure 
TKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVF
CEEEEEECHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCEEECCCCCCCCCCCCEEE
VTEDGAETDLDLGHYERFISTKMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITN
EECCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHCCHHHHHHHHHH
EIQAFIERGAASATCGEPDVAIVEIGGTVGDIESLPFLEAARQMSLRLGRNSACFVHLTL
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEH
VPFIATAGELKTKPTQHSVQKLREIGISPHVLLCRADRPIPDDESKKISLFSNVPEDAVI
HHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCEE
SVWDVDSIYKIPQMLHDQGLDRLICEELRLDPQPADLRMWSELVEKLQNPKHEVTIGMVG
EEECCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECC
KYVDLTESYKSLIEALRHASIHTSTKVNIEYIDSEELEANGTASLAHLDAVLVPGGFGRR
CHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHEEEEEECCCCCCC
GTEGKIAAVRYAREAKVPYLGICLGMQLAVIEFARDVVGLKQANSTEFDPNTPERVVALI
CCCCCEEEEEHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
TEWYDREGKVEKRTEDSDLGGTMRLGSQRCPIKPGTLAEAIYGKDVNERHRHRYEVNNRF
HHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCC
VPQLEAGGLVISARTPSEDLPEMMELPRAMHPWFVGVQFHPEFTSTPRDGHPLFKSFVQA
CCEECCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
AIACQQARAGAKA
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA