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The map label for this gene is alsR [H]

Identifier: 83719948

GI number: 83719948

Start: 214049

End: 215020

Strand: Reverse

Name: alsR [H]

Synonym: BTH_I0184

Alternate gene names: 83719948

Gene position: 215020-214049 (Counterclockwise)

Preceding gene: 83721109

Following gene: 83720365

Centisome position: 5.64

GC content: 67.8

Gene sequence:

>972_bases
GTGAGCGGATTCTTGCACCGTGAACGATTCAAGTCCAAGATAACGAATGACTTAATCAATACAGATTTTGGATCAATGTT
CGAACTCAGCCAGCTTCGCTGTTTCGTCGCCGTCGCGGAGGAATTGCACTTCGGGCGCGCGGCCGAGCGCTTGCACATGA
CGCAGCCGCCGCTGTCCCGGCAAGTGCGCCTGCTCGAACACCAGATCGGCACCGAATTGCTCGAGCGCACGAGCCGCTCG
GTGAAGCTGACGGCGGCGGGCCGCGGCTTCCTGCCCGATGCGGCCCGCATTCTGCGGCTCGCCGACGAGGCGGCGGCCAC
CGCGCGCCGTATCGCGACGGGCGCGGCCGGCACGCTCGCGATCGGCTTCACCGCATCGGTCGGCTACGGTCTGTTGCCGT
CGCTCGTGAGCGCGGTGCGCGCCGCGTCGCCCGACGTGCGCCTCACGCTGAAGGAGATGGTGAGCGGCGCGCAGCTCGAA
GCGCTCGATGCGCGGCTGATCGACGTCGGGCTGCTGCGCCCGCCCGTCGAGCACGGCGAGCTCGCGTCTCTGCCGTGCAT
GCGCGAAGCGCTCGTGCTCGCACTGCCGGCGGCGAGCGCCGACGCGTGGCCGAAGCGCCCGACGCTGCGCGATTGCGAAG
GCAAGCCGCTCCTGATGTATTCGCCCTACGAGGCGCGCTATTTCCACCAGTTGGTGAGCGGGCTGCTCGAGCGCACGGAC
GTGCTGCCCGACATCGTCGAATACGTGAGCCAGATCCATTCGATGCTGGCGCTCGTGCGCGCGGGCATCGGGGCCGCGCT
GATTCCGGCGGCGGCGTCGATGCTGCACTTCGAAGGGGTCGTCTACCGGCCGGTGCGCACGATGCCGGCGAAGCCCGTCG
AGCTGACGCTCGCGTATCGCAAGGACAACGACAATCCGGTGTTCGCCGCGCTGAAGGACGTGCTGCGCAAATCGCTCGCG
GCGAGCCGTTGA

Upstream 100 bases:

>100_bases
CGTGACCGGGAAAGACAGCAGGCCAGAGCCGATCTGGCGGGCGAATTCGGTGGGCGTATAGCGTGACATGAGCGTTCGTG
CCGGTGCGGCGTGACAAGTG

Downstream 100 bases:

>100_bases
AGCGGCGCGCGCTCGCGATCAGAGCGCCGCATCACACGGGCCACAGCGGCCCTTCCTGCATCGCGCCGATCTGTTCGCGC
AATTCGAGCACGCGCGCCTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSGFLHRERFKSKITNDLINTDFGSMFELSQLRCFVAVAEELHFGRAAERLHMTQPPLSRQVRLLEHQIGTELLERTSRS
VKLTAAGRGFLPDAARILRLADEAAATARRIATGAAGTLAIGFTASVGYGLLPSLVSAVRAASPDVRLTLKEMVSGAQLE
ALDARLIDVGLLRPPVEHGELASLPCMREALVLALPAASADAWPKRPTLRDCEGKPLLMYSPYEARYFHQLVSGLLERTD
VLPDIVEYVSQIHSMLALVRAGIGAALIPAAASMLHFEGVVYRPVRTMPAKPVELTLAYRKDNDNPVFAALKDVLRKSLA
ASR

Sequences:

>Translated_323_residues
MSGFLHRERFKSKITNDLINTDFGSMFELSQLRCFVAVAEELHFGRAAERLHMTQPPLSRQVRLLEHQIGTELLERTSRS
VKLTAAGRGFLPDAARILRLADEAAATARRIATGAAGTLAIGFTASVGYGLLPSLVSAVRAASPDVRLTLKEMVSGAQLE
ALDARLIDVGLLRPPVEHGELASLPCMREALVLALPAASADAWPKRPTLRDCEGKPLLMYSPYEARYFHQLVSGLLERTD
VLPDIVEYVSQIHSMLALVRAGIGAALIPAAASMLHFEGVVYRPVRTMPAKPVELTLAYRKDNDNPVFAALKDVLRKSLA
ASR
>Mature_322_residues
SGFLHRERFKSKITNDLINTDFGSMFELSQLRCFVAVAEELHFGRAAERLHMTQPPLSRQVRLLEHQIGTELLERTSRSV
KLTAAGRGFLPDAARILRLADEAAATARRIATGAAGTLAIGFTASVGYGLLPSLVSAVRAASPDVRLTLKEMVSGAQLEA
LDARLIDVGLLRPPVEHGELASLPCMREALVLALPAASADAWPKRPTLRDCEGKPLLMYSPYEARYFHQLVSGLLERTDV
LPDIVEYVSQIHSMLALVRAGIGAALIPAAASMLHFEGVVYRPVRTMPAKPVELTLAYRKDNDNPVFAALKDVLRKSLAA
SR

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=260, Percent_Identity=38.8461538461538, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1788887, Length=296, Percent_Identity=34.7972972972973, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI2367136, Length=289, Percent_Identity=31.1418685121107, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1790399, Length=280, Percent_Identity=30, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1788748, Length=291, Percent_Identity=27.4914089347079, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI157672245, Length=248, Percent_Identity=29.8387096774194, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI145693105, Length=261, Percent_Identity=25.2873563218391, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787806, Length=244, Percent_Identity=26.2295081967213, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87081904, Length=154, Percent_Identity=31.1688311688312, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787601, Length=298, Percent_Identity=24.496644295302, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=26.5873015873016, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI145693193, Length=125, Percent_Identity=33.6, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790208, Length=299, Percent_Identity=26.7558528428094, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787589, Length=139, Percent_Identity=35.2517985611511, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994962, Length=105, Percent_Identity=35.2380952380952, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788626, Length=280, Percent_Identity=26.4285714285714, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789173, Length=122, Percent_Identity=36.0655737704918, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35227; Mature: 35096

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGFLHRERFKSKITNDLINTDFGSMFELSQLRCFVAVAEELHFGRAAERLHMTQPPLSR
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
QVRLLEHQIGTELLERTSRSVKLTAAGRGFLPDAARILRLADEAAATARRIATGAAGTLA
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
IGFTASVGYGLLPSLVSAVRAASPDVRLTLKEMVSGAQLEALDARLIDVGLLRPPVEHGE
EEHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC
LASLPCMREALVLALPAASADAWPKRPTLRDCEGKPLLMYSPYEARYFHQLVSGLLERTD
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHC
VLPDIVEYVSQIHSMLALVRAGIGAALIPAAASMLHFEGVVYRPVRTMPAKPVELTLAYR
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEECCHHCCCCCCEEEEEEEE
KDNDNPVFAALKDVLRKSLAASR
CCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGFLHRERFKSKITNDLINTDFGSMFELSQLRCFVAVAEELHFGRAAERLHMTQPPLSR
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
QVRLLEHQIGTELLERTSRSVKLTAAGRGFLPDAARILRLADEAAATARRIATGAAGTLA
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
IGFTASVGYGLLPSLVSAVRAASPDVRLTLKEMVSGAQLEALDARLIDVGLLRPPVEHGE
EEHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC
LASLPCMREALVLALPAASADAWPKRPTLRDCEGKPLLMYSPYEARYFHQLVSGLLERTD
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHC
VLPDIVEYVSQIHSMLALVRAGIGAALIPAAASMLHFEGVVYRPVRTMPAKPVELTLAYR
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEECCHHCCCCCCEEEEEEEE
KDNDNPVFAALKDVLRKSLAASR
CCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]