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The map label for this gene is aaeR [H]

Identifier: 83719834

GI number: 83719834

Start: 308525

End: 310240

Strand: Reverse

Name: aaeR [H]

Synonym: BTH_I0276

Alternate gene names: 83719834

Gene position: 310240-308525 (Counterclockwise)

Preceding gene: 83721425

Following gene: 83720065

Centisome position: 8.14

GC content: 67.02

Gene sequence:

>1716_bases
ATGAATCAGCTACAAGTGATGCGCGTCTTCACGCGCGTGGTCGATCTCGCGAGCTTCAACCTCGCCGCGCGACAGCTCGG
CATGTCGGCCGCGGCCGTCACGCGCAGCATCGGCATGCTGGAAGCCCATCTGAACATGCGCTTGCTGAACCGCACAACGC
GCAGCCTGTCGCTCACCGAGGCCGGCCGCGAGTACCTGGACGGCTGCCGCGCGATCATCGACAAGCTCGACGAAATCGAA
TCGAATCTCGTGCAGGCGACGCGCGATCCGCGCGGCACGCTGCGCATCGCGTCGTCGATGAGCTTCGCCGCCTCGGGCCT
CGGGCCGCTGCTCGCCGCGTACCGCATCCTGCACCCGCGCGTCGCGTTCGACGTGACGACGTTCGATACGCACGTCGACA
TGGTCGAAGGCGCGTACGACGTGTGCTTCTCCGACGATCGCCATCTCGCGAGCTCGACGCTCGTGAGCCGCGCGCTGACG
ACGATCCGCGAGGTGACAGTCGCGTCGCCTGCCTATCTCGCGCGCCACGGCACGCCGCACAATCCGGCCGAGCTCGGCGA
GCACAGCCTGCTTGCGATATCGGACGGCACCGCGCGCTCGTGGGAATTCGCCGATGCGAGCGGCGCGTATCGCGTTTACG
CGGGCAGCGTGCTCGTATCGGAAAACAGCGCGATGGTGCGCATCGCCGCGCTCAACCACATGGGCATCGCGCAGTTGCCG
CTCCCTCTTGTCGCGGCCGATCTCGACGCGCGCATGCTCGTGCCGCTGCTGCAGCGCCGCAAAACCGCCGCGCCGCTGCA
GCGTGCCGATCTCCGAGATGCGCAGCATCGCGCGAAAACGCGCGAGCAGGCCGTCCGTTTCGGTTCGCGCGCGCTCGACG
AGGCTCGACAATGCGACGTCGTCGAGCGTGTCCGCACGCTGCGCCGCGTGCGCGAGCAGCGTATGCACGTGCGCGAGCGG
CGTGCGCAGATCGTGCGCGATGCCGTCGCATACGCCCTTCACCTCGTTCATCAGACGTTCGACCTCCTCGAGCATGTGAT
TGACGAGGTGCGACAGCATGTCGATCTCGTCGCGCCCGCCGACGGGCAGGCGCTGCCCGAGATCGCCTTGCGCGATGCGC
TGCGTGACGTGGCGGATCGCCTTGAGCCGGCTCATCTGCCGCACGCTCAAAGCGAGTCCGCCCGCGATGCCGGCCACGAG
GCACAGAACGCCGCCGCCGATCAGTGCGTTGATGATCGCCTCGCGAATGCGCAGGATGTGCGTGAGGTCGCGTGCGAGCA
CGAGCTTGTCGCCGTTCGCGCGCACCTCGGCCATCGCGCGCACGACGGGCGCAACCTGATCGCCTGCGATCTTCAGCGTG
TGGTCGAGCGTCGTGCCGGTGCGATACGTCGTCAGCTCGGACGGAAACGCGAGCACGTCGCCCGCGATGTGCGTGCCGTT
CGCGGAGAAGAGGCCGTAATAGTTCGTGTGCATTCGCTCGTGTTCGAGCCGGCGATGAATCGCGCCGGCGATGTCGCCGT
CCGGCATCGCATCGAAGTAGATCATCTGCCAGTCGATCACGACATCGGTCTCGCGTTCCATGTCGTGCGTGATCGCCGCC
GCGATGAAGCCGAGCAGCACCATTACCGAAATCGAGAACGTCGCCGCATAGACGGTGAGCAGACGGAACGTCGTCGAATA
CCACCGACGTCCCGGCGCGGCGGGCGCATGGCGTGA

Upstream 100 bases:

>100_bases
TCACATTGCGCGAACATGAAAAATCCTTAATCCACGCGGCGCGCCCGTTTTACTCGCGCTCGCGGATCATGTGCGCACTC
TCCGCCCGTCGAGCAGGAAC

Downstream 100 bases:

>100_bases
AGCGTCCATCGGAAAAATCCGCTTACGAAAGGATGTAGCCCGCGCCGCGCACGGTCCGGATCATCGGCGTCGCATCCGGC
GGATCGATCTTCTTGCGCAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 571; Mature: 571

Protein sequence:

>571_residues
MNQLQVMRVFTRVVDLASFNLAARQLGMSAAAVTRSIGMLEAHLNMRLLNRTTRSLSLTEAGREYLDGCRAIIDKLDEIE
SNLVQATRDPRGTLRIASSMSFAASGLGPLLAAYRILHPRVAFDVTTFDTHVDMVEGAYDVCFSDDRHLASSTLVSRALT
TIREVTVASPAYLARHGTPHNPAELGEHSLLAISDGTARSWEFADASGAYRVYAGSVLVSENSAMVRIAALNHMGIAQLP
LPLVAADLDARMLVPLLQRRKTAAPLQRADLRDAQHRAKTREQAVRFGSRALDEARQCDVVERVRTLRRVREQRMHVRER
RAQIVRDAVAYALHLVHQTFDLLEHVIDEVRQHVDLVAPADGQALPEIALRDALRDVADRLEPAHLPHAQSESARDAGHE
AQNAAADQCVDDRLANAQDVREVACEHELVAVRAHLGHRAHDGRNLIACDLQRVVERRAGAIRRQLGRKREHVARDVRAV
RGEEAVIVRVHSLVFEPAMNRAGDVAVRHRIEVDHLPVDHDIGLAFHVVRDRRRDEAEQHHYRNRERRRIDGEQTERRRI
PPTSRRGGRMA

Sequences:

>Translated_571_residues
MNQLQVMRVFTRVVDLASFNLAARQLGMSAAAVTRSIGMLEAHLNMRLLNRTTRSLSLTEAGREYLDGCRAIIDKLDEIE
SNLVQATRDPRGTLRIASSMSFAASGLGPLLAAYRILHPRVAFDVTTFDTHVDMVEGAYDVCFSDDRHLASSTLVSRALT
TIREVTVASPAYLARHGTPHNPAELGEHSLLAISDGTARSWEFADASGAYRVYAGSVLVSENSAMVRIAALNHMGIAQLP
LPLVAADLDARMLVPLLQRRKTAAPLQRADLRDAQHRAKTREQAVRFGSRALDEARQCDVVERVRTLRRVREQRMHVRER
RAQIVRDAVAYALHLVHQTFDLLEHVIDEVRQHVDLVAPADGQALPEIALRDALRDVADRLEPAHLPHAQSESARDAGHE
AQNAAADQCVDDRLANAQDVREVACEHELVAVRAHLGHRAHDGRNLIACDLQRVVERRAGAIRRQLGRKREHVARDVRAV
RGEEAVIVRVHSLVFEPAMNRAGDVAVRHRIEVDHLPVDHDIGLAFHVVRDRRRDEAEQHHYRNRERRRIDGEQTERRRI
PPTSRRGGRMA
>Mature_571_residues
MNQLQVMRVFTRVVDLASFNLAARQLGMSAAAVTRSIGMLEAHLNMRLLNRTTRSLSLTEAGREYLDGCRAIIDKLDEIE
SNLVQATRDPRGTLRIASSMSFAASGLGPLLAAYRILHPRVAFDVTTFDTHVDMVEGAYDVCFSDDRHLASSTLVSRALT
TIREVTVASPAYLARHGTPHNPAELGEHSLLAISDGTARSWEFADASGAYRVYAGSVLVSENSAMVRIAALNHMGIAQLP
LPLVAADLDARMLVPLLQRRKTAAPLQRADLRDAQHRAKTREQAVRFGSRALDEARQCDVVERVRTLRRVREQRMHVRER
RAQIVRDAVAYALHLVHQTFDLLEHVIDEVRQHVDLVAPADGQALPEIALRDALRDVADRLEPAHLPHAQSESARDAGHE
AQNAAADQCVDDRLANAQDVREVACEHELVAVRAHLGHRAHDGRNLIACDLQRVVERRAGAIRRQLGRKREHVARDVRAV
RGEEAVIVRVHSLVFEPAMNRAGDVAVRHRIEVDHLPVDHDIGLAFHVVRDRRRDEAEQHHYRNRERRRIDGEQTERRRI
PPTSRRGGRMA

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=264, Percent_Identity=32.9545454545455, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1786401, Length=235, Percent_Identity=32.3404255319149, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI145693193, Length=243, Percent_Identity=29.6296296296296, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787128, Length=256, Percent_Identity=29.6875, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87081978, Length=244, Percent_Identity=31.1475409836066, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789440, Length=232, Percent_Identity=27.1551724137931, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1787589, Length=259, Percent_Identity=26.2548262548263, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789173, Length=255, Percent_Identity=27.843137254902, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1788706, Length=241, Percent_Identity=27.3858921161826, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI145693105, Length=119, Percent_Identity=31.0924369747899, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 63968; Mature: 63968

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS50931 HTH_LYSR ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLQVMRVFTRVVDLASFNLAARQLGMSAAAVTRSIGMLEAHLNMRLLNRTTRSLSLTE
CCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGREYLDGCRAIIDKLDEIESNLVQATRDPRGTLRIASSMSFAASGLGPLLAAYRILHPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCHHHHHHHHHHHCCH
VAFDVTTFDTHVDMVEGAYDVCFSDDRHLASSTLVSRALTTIREVTVASPAYLARHGTPH
HEEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
NPAELGEHSLLAISDGTARSWEFADASGAYRVYAGSVLVSENSAMVRIAALNHMGIAQLP
CHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEEECEEEEECCCCEEEEEECCCCCCHHCC
LPLVAADLDARMLVPLLQRRKTAAPLQRADLRDAQHRAKTREQAVRFGSRALDEARQCDV
HHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
VERVRTLRRVREQRMHVRERRAQIVRDAVAYALHLVHQTFDLLEHVIDEVRQHVDLVAPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCC
DGQALPEIALRDALRDVADRLEPAHLPHAQSESARDAGHEAQNAAADQCVDDRLANAQDV
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCHHHH
REVACEHELVAVRAHLGHRAHDGRNLIACDLQRVVERRAGAIRRQLGRKREHVARDVRAV
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGEEAVIVRVHSLVFEPAMNRAGDVAVRHRIEVDHLPVDHDIGLAFHVVRDRRRDEAEQH
CCCCCEEHHHHHHHHHHHHCCCCCHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
HYRNRERRRIDGEQTERRRIPPTSRRGGRMA
HHHHHHHHCCCCHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MNQLQVMRVFTRVVDLASFNLAARQLGMSAAAVTRSIGMLEAHLNMRLLNRTTRSLSLTE
CCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGREYLDGCRAIIDKLDEIESNLVQATRDPRGTLRIASSMSFAASGLGPLLAAYRILHPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCHHHHHHHHHHHCCH
VAFDVTTFDTHVDMVEGAYDVCFSDDRHLASSTLVSRALTTIREVTVASPAYLARHGTPH
HEEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
NPAELGEHSLLAISDGTARSWEFADASGAYRVYAGSVLVSENSAMVRIAALNHMGIAQLP
CHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEEECEEEEECCCCEEEEEECCCCCCHHCC
LPLVAADLDARMLVPLLQRRKTAAPLQRADLRDAQHRAKTREQAVRFGSRALDEARQCDV
HHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
VERVRTLRRVREQRMHVRERRAQIVRDAVAYALHLVHQTFDLLEHVIDEVRQHVDLVAPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCC
DGQALPEIALRDALRDVADRLEPAHLPHAQSESARDAGHEAQNAAADQCVDDRLANAQDV
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCHHHH
REVACEHELVAVRAHLGHRAHDGRNLIACDLQRVVERRAGAIRRQLGRKREHVARDVRAV
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGEEAVIVRVHSLVFEPAMNRAGDVAVRHRIEVDHLPVDHDIGLAFHVVRDRRRDEAEQH
CCCCCEEHHHHHHHHHHHHCCCCCHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
HYRNRERRRIDGEQTERRRIPPTSRRGGRMA
HHHHHHHHCCCCHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]