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The map label for this gene is cbaA [H]

Identifier: 83719802

GI number: 83719802

Start: 3308326

End: 3309930

Strand: Reverse

Name: cbaA [H]

Synonym: BTH_I2874

Alternate gene names: 83719802

Gene position: 3309930-3308326 (Counterclockwise)

Preceding gene: 83720288

Following gene: 83721626

Centisome position: 86.89

GC content: 66.23

Gene sequence:

>1605_bases
GTGCTCGCCCATTTCTGGCTCGCGTTCGCGGTCTTCGGCGTCGCGCTGTTGCTCGGCGCGTGGCAGATGCTCGCGCGCAG
CCCGCTGCTTCCCTGGCTCGGCAACCCCGAGCTCTACTATCGCTCGGTGACCGCGCACGGTTCCGTGATGGGTTATGTGT
TTCCGACGCTGATCGCGATGGGCTTCGGCTACGCGATCAGCGAGCTCGCGCTCAAGATGCCGCTCGTCGGCCGCCGCTGG
GCGTGGACGGGCTTCTGGCTGATCGCGCTCGGCTCGGTCGTCGCGATGACGCCCGTGTCGCTCGGCCTGTCGTCGGTGCT
GTACACGTTCTATCCGCCGATGATCGGCAATCCGTTCTACTACCTCGGCGTCGTGCTCGTCGTCGTCGGCTCGTGGATCT
GGGTCGGGCTGATGTCGGTGAACCTCTATGCGTGGAAGAAGGCCAATCCCGGCACGCCGATTCCGCTCGCGATGTTCGCG
AACGTCGCGGGCGCGTATCTGTGGGGCTGGACCGCAGTCGGCGCCGCGATCGAGATCCTGTTCCAGATCCTGCCCGTCGC
GGTCGGGCTCAAGTCGACGATCGACGCGGGCCTCGCGCGCGTGTTCTTCTCGTGGACGCTGCACGCGATCGTCTACTTCT
GGCTGATCCCCGCGTACATCGCGTACTACACGCTCGTGCCGCGCGCGATCGGCGGCAAGCTGTACAGCGACGGAATGGCG
CGCATCTCCTTCATTCTGTTCCTCGTCGGCGCGATGCCGATCGGCGTGCACCACCTGTTCGCCGATCCGCAGGTCGGCTC
GGGCTTCAAGTTCCTGCAATCGGTGTTCACGGCGCTCGTCGCGGTGCCGACGCTCCTCACGGTGTTCACCGTGTGCGCGT
CGGTCGAGATCGCCGCGCGCCTGCGCGGCGGCAAGGGCGCGTTCGGCTGGCTGCGCGCGCTGCCGTGGCATGAGCCGATG
ATGCTCGCCGTCGCGTTCTCGTTCGTGATGCTCGGCTTCGGCGGCGCGGGCGGGCTCATCAACATGAGCTACCAGCTCGA
TTCGACGATTCACAACACGCAGTGGATCACGGGGCACTTCCACCTGATCTTCGGCGGCGCCGTCGTCATCATGTACTTCG
CGATCGCGTATGAGCTGTGGCCGCATCTGACCGGCCGCGCGCTCGGCAGCCTGCGCCTCGTGAAGACGCAGCTCTGGCTG
TGGTTCATCGGCATGATCGTCACGACGTTCCCGTGGCACTACGTCGGCATCCTCGGCATGCCGCGCCGGATGGCCTATTA
CGACTACAGCGATCCGGCGCTCGCGCCGCAGGCGGCGTGGGTGATCATGTCGGTCGTCGGCGCGCTGATCCTCGTCGCGT
CGGCCGTGCTGTTCTTCGTCGTGCTGATACGCAGCCATCGCGGCGAGAAGGTGACGCCGGCCGAGTTCACGTTCAGCTCG
GCCGTTCACGAGCCGAGGACGCTGCCCGTCGCGCTCAACAGCTTCGGGCTGTGGATCGCGCTGATGATCGGCCTCACGGT
CGTCAACTACGGCTATCCGATCGCGCAGTTGATGGCGCTCAAGCAACCGTCGGTGCCGGCGATCTACATGGGGGCGCAGC
GATGA

Upstream 100 bases:

>100_bases
GAGGGGATGTGGGCGCACGTCAAGGTCATTGACCGTGCGGAATTCGACAAACTGGCGTCCAGCGCGCGGAGACTGAGCTG
TGTTAAAGAATAATCGACTG

Downstream 100 bases:

>100_bases
GCACGGAACGTCTGTTTTCGATTCGCAACCGCTGGTTTACGGTCAGCGTCGGGCTCACGCTGTTCGCGGTGATCGCGTCG
GTGCTGATCGGCTTCGTCTG

Product: cytochrome C oxidase subunit 1

Products: NA

Alternate protein names: Cytochrome c ba(3) subunit I; Cytochrome c oxidase polypeptide I; Cytochrome cba3 subunit 1 [H]

Number of amino acids: Translated: 534; Mature: 534

Protein sequence:

>534_residues
MLAHFWLAFAVFGVALLLGAWQMLARSPLLPWLGNPELYYRSVTAHGSVMGYVFPTLIAMGFGYAISELALKMPLVGRRW
AWTGFWLIALGSVVAMTPVSLGLSSVLYTFYPPMIGNPFYYLGVVLVVVGSWIWVGLMSVNLYAWKKANPGTPIPLAMFA
NVAGAYLWGWTAVGAAIEILFQILPVAVGLKSTIDAGLARVFFSWTLHAIVYFWLIPAYIAYYTLVPRAIGGKLYSDGMA
RISFILFLVGAMPIGVHHLFADPQVGSGFKFLQSVFTALVAVPTLLTVFTVCASVEIAARLRGGKGAFGWLRALPWHEPM
MLAVAFSFVMLGFGGAGGLINMSYQLDSTIHNTQWITGHFHLIFGGAVVIMYFAIAYELWPHLTGRALGSLRLVKTQLWL
WFIGMIVTTFPWHYVGILGMPRRMAYYDYSDPALAPQAAWVIMSVVGALILVASAVLFFVVLIRSHRGEKVTPAEFTFSS
AVHEPRTLPVALNSFGLWIALMIGLTVVNYGYPIAQLMALKQPSVPAIYMGAQR

Sequences:

>Translated_534_residues
MLAHFWLAFAVFGVALLLGAWQMLARSPLLPWLGNPELYYRSVTAHGSVMGYVFPTLIAMGFGYAISELALKMPLVGRRW
AWTGFWLIALGSVVAMTPVSLGLSSVLYTFYPPMIGNPFYYLGVVLVVVGSWIWVGLMSVNLYAWKKANPGTPIPLAMFA
NVAGAYLWGWTAVGAAIEILFQILPVAVGLKSTIDAGLARVFFSWTLHAIVYFWLIPAYIAYYTLVPRAIGGKLYSDGMA
RISFILFLVGAMPIGVHHLFADPQVGSGFKFLQSVFTALVAVPTLLTVFTVCASVEIAARLRGGKGAFGWLRALPWHEPM
MLAVAFSFVMLGFGGAGGLINMSYQLDSTIHNTQWITGHFHLIFGGAVVIMYFAIAYELWPHLTGRALGSLRLVKTQLWL
WFIGMIVTTFPWHYVGILGMPRRMAYYDYSDPALAPQAAWVIMSVVGALILVASAVLFFVVLIRSHRGEKVTPAEFTFSS
AVHEPRTLPVALNSFGLWIALMIGLTVVNYGYPIAQLMALKQPSVPAIYMGAQR
>Mature_534_residues
MLAHFWLAFAVFGVALLLGAWQMLARSPLLPWLGNPELYYRSVTAHGSVMGYVFPTLIAMGFGYAISELALKMPLVGRRW
AWTGFWLIALGSVVAMTPVSLGLSSVLYTFYPPMIGNPFYYLGVVLVVVGSWIWVGLMSVNLYAWKKANPGTPIPLAMFA
NVAGAYLWGWTAVGAAIEILFQILPVAVGLKSTIDAGLARVFFSWTLHAIVYFWLIPAYIAYYTLVPRAIGGKLYSDGMA
RISFILFLVGAMPIGVHHLFADPQVGSGFKFLQSVFTALVAVPTLLTVFTVCASVEIAARLRGGKGAFGWLRALPWHEPM
MLAVAFSFVMLGFGGAGGLINMSYQLDSTIHNTQWITGHFHLIFGGAVVIMYFAIAYELWPHLTGRALGSLRLVKTQLWL
WFIGMIVTTFPWHYVGILGMPRRMAYYDYSDPALAPQAAWVIMSVVGALILVASAVLFFVVLIRSHRGEKVTPAEFTFSS
AVHEPRTLPVALNSFGLWIALMIGLTVVNYGYPIAQLMALKQPSVPAIYMGAQR

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. This Ubiquinol Oxidase Shows Proton Pump Activity Across The Membrane In Addition To The Electron T

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=485, Percent_Identity=25.5670103092783, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1786634, Length=502, Percent_Identity=23.7051792828685, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6226519, Length=261, Percent_Identity=29.1187739463602, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 58661; Mature: 58661

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50855 COX1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAHFWLAFAVFGVALLLGAWQMLARSPLLPWLGNPELYYRSVTAHGSVMGYVFPTLIAM
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
GFGYAISELALKMPLVGRRWAWTGFWLIALGSVVAMTPVSLGLSSVLYTFYPPMIGNPFY
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
YLGVVLVVVGSWIWVGLMSVNLYAWKKANPGTPIPLAMFANVAGAYLWGWTAVGAAIEIL
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FQILPVAVGLKSTIDAGLARVFFSWTLHAIVYFWLIPAYIAYYTLVPRAIGGKLYSDGMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RISFILFLVGAMPIGVHHLFADPQVGSGFKFLQSVFTALVAVPTLLTVFTVCASVEIAAR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRGGKGAFGWLRALPWHEPMMLAVAFSFVMLGFGGAGGLINMSYQLDSTIHNTQWITGHF
HCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEEH
HLIFGGAVVIMYFAIAYELWPHLTGRALGSLRLVKTQLWLWFIGMIVTTFPWHYVGILGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
PRRMAYYDYSDPALAPQAAWVIMSVVGALILVASAVLFFVVLIRSHRGEKVTPAEFTFSS
CCHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
AVHEPRTLPVALNSFGLWIALMIGLTVVNYGYPIAQLMALKQPSVPAIYMGAQR
HCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEECCCCC
>Mature Secondary Structure
MLAHFWLAFAVFGVALLLGAWQMLARSPLLPWLGNPELYYRSVTAHGSVMGYVFPTLIAM
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
GFGYAISELALKMPLVGRRWAWTGFWLIALGSVVAMTPVSLGLSSVLYTFYPPMIGNPFY
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
YLGVVLVVVGSWIWVGLMSVNLYAWKKANPGTPIPLAMFANVAGAYLWGWTAVGAAIEIL
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FQILPVAVGLKSTIDAGLARVFFSWTLHAIVYFWLIPAYIAYYTLVPRAIGGKLYSDGMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RISFILFLVGAMPIGVHHLFADPQVGSGFKFLQSVFTALVAVPTLLTVFTVCASVEIAAR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRGGKGAFGWLRALPWHEPMMLAVAFSFVMLGFGGAGGLINMSYQLDSTIHNTQWITGHF
HCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEEH
HLIFGGAVVIMYFAIAYELWPHLTGRALGSLRLVKTQLWLWFIGMIVTTFPWHYVGILGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
PRRMAYYDYSDPALAPQAAWVIMSVVGALILVASAVLFFVVLIRSHRGEKVTPAEFTFSS
CCHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
AVHEPRTLPVALNSFGLWIALMIGLTVVNYGYPIAQLMALKQPSVPAIYMGAQR
HCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7657607; 10338009; 10775261 [H]