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The map label for this gene is zraR [H]

Identifier: 83719739

GI number: 83719739

Start: 595648

End: 597036

Strand: Direct

Name: zraR [H]

Synonym: BTH_I0526

Alternate gene names: 83719739

Gene position: 595648-597036 (Clockwise)

Preceding gene: 83721259

Following gene: 83721346

Centisome position: 15.64

GC content: 68.32

Gene sequence:

>1389_bases
ATGACGACTAGCGCGATCATCGGGGGGCTCTCCCGGGGATCCATCCGACAGCGACCGTTGATTTACTGGACGCATCAGCC
ATCGACGCTGCTGCGCAAGGAACTCGCGCGCCGCGACTGGAAGATCTGCGTCGTCACGAGCGCGAACCAGGTGCGCACGA
CGGCGGGCGAGGTCACGGGCGGCATTCTCGATCTGAGCGCCGTGTCGATCGACGAGATGAACGCGGTCGCGGCCGTATGC
GCGTCGCTGCGCAACGTCGCGTGGGTCGCGCTCGTCGAGGCGCATCAGGCGAACGTGCCGAACGTGCGCGCGCTGCTGCG
CGATTACTGTTTCGACTACATCACGCTGCCTGCGTCGCATCAGCGGATCGCGGATGCGGTCGGCCACGCGTACGGGATGG
AGTGCCTGTTCGCGCCGAGCACGGCGCCCATCGCGTCCGCCGATCAGGGGATGATCGGCACTTGCGATGCGATGCTGCAA
CTGTTCGACGCGGTGCGCCGGATCGCGCGCACCGATGCGCCCGTGCTCGTGTCGGGCGAGACAGGCACCGGCAAGGAACT
CACCGCGGCCGCGATCCACCAGCATTCCGCACGCCGCGCGGGCCCGTTCGTCGCGGTCAACTGCGGCGCGATTCCGCCGC
ATCTGCTGCAGTCCGAACTGTTCGGCTACGAGCGCGGCGCGTTCACCGGCGCGAGCGCGCGCAAGATCGGCCATGTCGAA
TCGGCGAACGGCGGCACGCTGTTGCTCGACGAAATCGGCGATCTGCCGCTCGAAAGCCAGGCGAGCCTGCTGCGCTTCCT
GCAGGAGCGCACGATCCACCGGCTGGGCAGCAGCGATCCGGTGCCCGTCGACGTGCGCATCGTGTCGGCGACGCACGTCG
ATCTGCGCGGCGCGATGAACGAAGGGCGCTTCCGTGCGGATCTGTATCACCGGCTGTGCGTGCTGCGTGTCGATCAACCG
CCGCTGCGCGCGCGCGGCAAGGACATCGAGCTGCTCGCACGGCACATGCTCGAGCGCTTTCGCGCCGACGCGCGCCATCG
CGTGCGCGGCTTCTCCACCGATGCGATTTCGGCGCTCTACAAGCACGACTGGCCGGGCAACGTGCGCGAGCTCATCAATC
GCGTGCGCCGCGCGCTCGTGATGGCGGAAGGCCGGCTCATCACCGCGCACGATCTCGAGCTCGGCCACTGCATCGAGGTC
GCGCCGCTGTCGGTCGCCGCGATCCGCAAATCGATCGAGCGGGAAGTGATCGAGCTCGCGCTGCTGCGCAATCGCGGGCG
TCTCGCGGGCACCGCGCGCGAACTCGGCATCTCGCGCGCGACGCTGTATCGATGGATGGAAGCGTACGGCATCGAGCGTC
CGCGCAGCGTCGCCTCGTCCACCAACTGA

Upstream 100 bases:

>100_bases
CTCCCATCCCGCACTGCATTGCCGGTAGGCAGACGATCGTCGGCTTTCGCCGTACACGCATTCGTCGAGTCACACAGTCA
GTTCATGATCGGAGGCACCA

Downstream 100 bases:

>100_bases
CACGCGGGCGCGCCGCGGCGAAAGCGGCGCGCCCGCGCGAGCGCCGCCGTCAGGACGACGCGGCGGCATCGGCGGAGGCC
GCGTGCGCCGTCCCGCGCCG

Product: sigma-54 dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MTTSAIIGGLSRGSIRQRPLIYWTHQPSTLLRKELARRDWKICVVTSANQVRTTAGEVTGGILDLSAVSIDEMNAVAAVC
ASLRNVAWVALVEAHQANVPNVRALLRDYCFDYITLPASHQRIADAVGHAYGMECLFAPSTAPIASADQGMIGTCDAMLQ
LFDAVRRIARTDAPVLVSGETGTGKELTAAAIHQHSARRAGPFVAVNCGAIPPHLLQSELFGYERGAFTGASARKIGHVE
SANGGTLLLDEIGDLPLESQASLLRFLQERTIHRLGSSDPVPVDVRIVSATHVDLRGAMNEGRFRADLYHRLCVLRVDQP
PLRARGKDIELLARHMLERFRADARHRVRGFSTDAISALYKHDWPGNVRELINRVRRALVMAEGRLITAHDLELGHCIEV
APLSVAAIRKSIEREVIELALLRNRGRLAGTARELGISRATLYRWMEAYGIERPRSVASSTN

Sequences:

>Translated_462_residues
MTTSAIIGGLSRGSIRQRPLIYWTHQPSTLLRKELARRDWKICVVTSANQVRTTAGEVTGGILDLSAVSIDEMNAVAAVC
ASLRNVAWVALVEAHQANVPNVRALLRDYCFDYITLPASHQRIADAVGHAYGMECLFAPSTAPIASADQGMIGTCDAMLQ
LFDAVRRIARTDAPVLVSGETGTGKELTAAAIHQHSARRAGPFVAVNCGAIPPHLLQSELFGYERGAFTGASARKIGHVE
SANGGTLLLDEIGDLPLESQASLLRFLQERTIHRLGSSDPVPVDVRIVSATHVDLRGAMNEGRFRADLYHRLCVLRVDQP
PLRARGKDIELLARHMLERFRADARHRVRGFSTDAISALYKHDWPGNVRELINRVRRALVMAEGRLITAHDLELGHCIEV
APLSVAAIRKSIEREVIELALLRNRGRLAGTARELGISRATLYRWMEAYGIERPRSVASSTN
>Mature_461_residues
TTSAIIGGLSRGSIRQRPLIYWTHQPSTLLRKELARRDWKICVVTSANQVRTTAGEVTGGILDLSAVSIDEMNAVAAVCA
SLRNVAWVALVEAHQANVPNVRALLRDYCFDYITLPASHQRIADAVGHAYGMECLFAPSTAPIASADQGMIGTCDAMLQL
FDAVRRIARTDAPVLVSGETGTGKELTAAAIHQHSARRAGPFVAVNCGAIPPHLLQSELFGYERGAFTGASARKIGHVES
ANGGTLLLDEIGDLPLESQASLLRFLQERTIHRLGSSDPVPVDVRIVSATHVDLRGAMNEGRFRADLYHRLCVLRVDQPP
LRARGKDIELLARHMLERFRADARHRVRGFSTDAISALYKHDWPGNVRELINRVRRALVMAEGRLITAHDLELGHCIEVA
PLSVAAIRKSIEREVIELALLRNRGRLAGTARELGISRATLYRWMEAYGIERPRSVASSTN

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=417, Percent_Identity=39.0887290167866, Blast_Score=269, Evalue=3e-73,
Organism=Escherichia coli, GI1788550, Length=380, Percent_Identity=41.0526315789474, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1788905, Length=396, Percent_Identity=37.3737373737374, Blast_Score=244, Evalue=9e-66,
Organism=Escherichia coli, GI1789233, Length=331, Percent_Identity=43.202416918429, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI87082117, Length=319, Percent_Identity=43.5736677115987, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1790299, Length=376, Percent_Identity=38.2978723404255, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1789087, Length=308, Percent_Identity=40.9090909090909, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1786524, Length=325, Percent_Identity=40.9230769230769, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI87082152, Length=319, Percent_Identity=42.0062695924765, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI87081872, Length=237, Percent_Identity=43.8818565400844, Blast_Score=197, Evalue=9e-52,
Organism=Escherichia coli, GI1787583, Length=321, Percent_Identity=36.1370716510903, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI87081858, Length=294, Percent_Identity=33.6734693877551, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1789828, Length=243, Percent_Identity=36.2139917695473, Blast_Score=136, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50623; Mature: 50492

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSAIIGGLSRGSIRQRPLIYWTHQPSTLLRKELARRDWKICVVTSANQVRTTAGEVTG
CCCHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCC
GILDLSAVSIDEMNAVAAVCASLRNVAWVALVEAHQANVPNVRALLRDYCFDYITLPASH
CEEEEEECCHHHHHHHHHHHHHHHHHHHHEEEHHHCCCCCHHHHHHHHHHHHHEECCCCH
QRIADAVGHAYGMECLFAPSTAPIASADQGMIGTCDAMLQLFDAVRRIARTDAPVLVSGE
HHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECC
TGTGKELTAAAIHQHSARRAGPFVAVNCGAIPPHLLQSELFGYERGAFTGASARKIGHVE
CCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCHHHCCCCC
SANGGTLLLDEIGDLPLESQASLLRFLQERTIHRLGSSDPVPVDVRIVSATHVDLRGAMN
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEHHHCCCC
EGRFRADLYHRLCVLRVDQPPLRARGKDIELLARHMLERFRADARHRVRGFSTDAISALY
CCCHHHHHHHCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KHDWPGNVRELINRVRRALVMAEGRLITAHDLELGHCIEVAPLSVAAIRKSIEREVIELA
HCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHH
LLRNRGRLAGTARELGISRATLYRWMEAYGIERPRSVASSTN
HHHCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCHHHHCCCC
>Mature Secondary Structure 
TTSAIIGGLSRGSIRQRPLIYWTHQPSTLLRKELARRDWKICVVTSANQVRTTAGEVTG
CCHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCC
GILDLSAVSIDEMNAVAAVCASLRNVAWVALVEAHQANVPNVRALLRDYCFDYITLPASH
CEEEEEECCHHHHHHHHHHHHHHHHHHHHEEEHHHCCCCCHHHHHHHHHHHHHEECCCCH
QRIADAVGHAYGMECLFAPSTAPIASADQGMIGTCDAMLQLFDAVRRIARTDAPVLVSGE
HHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECC
TGTGKELTAAAIHQHSARRAGPFVAVNCGAIPPHLLQSELFGYERGAFTGASARKIGHVE
CCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCHHHCCCCC
SANGGTLLLDEIGDLPLESQASLLRFLQERTIHRLGSSDPVPVDVRIVSATHVDLRGAMN
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEHHHCCCC
EGRFRADLYHRLCVLRVDQPPLRARGKDIELLARHMLERFRADARHRVRGFSTDAISALY
CCCHHHHHHHCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KHDWPGNVRELINRVRRALVMAEGRLITAHDLELGHCIEVAPLSVAAIRKSIEREVIELA
HCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHH
LLRNRGRLAGTARELGISRATLYRWMEAYGIERPRSVASSTN
HHHCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]