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The map label for this gene is yciC [H]

Identifier: 83719674

GI number: 83719674

Start: 5838

End: 7397

Strand: Reverse

Name: yciC [H]

Synonym: BTH_I0005

Alternate gene names: 83719674

Gene position: 7397-5838 (Counterclockwise)

Preceding gene: 83718965

Following gene: 83720591

Centisome position: 0.19

GC content: 66.47

Gene sequence:

>1560_bases
ATGCAATGCCGCGCCGGCAGTCCGGCGATCGATCGCACGGCATGCAAGCACCCACGTTCGTTTCGTTATCGAATCACACA
TCATGAAATCGCGGCCGTTCTGCCGCCGCGCGCGGCCGTCCGTCTATATTTGATGCACAATGCGGCTTTCCCGCCGCCCG
TTCGCGCCGGCCGCTCGCCGGTGCCGCCCCGTTTTCGGGGCGCGGCGGCTCGCTTCCCGCTTTTTTCGTTGGTGCGCACC
GCAATGAACCAGCCGTTGCCCGTCACCGTGCTGTCCGGCTTCCTCGGCGCCGGCAAGACCACGCTGCTCAATCACATCCT
CGCGAATCGCGCGGGCCTGAAGGTCGCCGTGATCGTCAACGATCTCGCCGCGGCCAACGTCGACGCGACGTTCGTGCGCG
GCGCGACCGAGTTGTCGCATGTCGAAGAGCACTTCGTCGAGATGTCGAACGGCTGCATCTGCTGCACGCTGCGCGACGAT
CTGCTCGTCGAGATCCGCCGCCTCGCGGCCGAAAACCGCTTCGATGCGATCGTGATCGAATCGACCGGCATCGCCGAGCC
GATGCCCATCGCCGAAACCTTCACGTTCGTCGACGACGACGGCTCGGCGCTCGAGGACGTCGCGCGCCTCGACACGATGG
TCACCGTCGTCGACGCGTTCAACTTCCTGCGCGATTATGCGCGCGACGACGCGCTCGCGGAACACGGCCTCGCCGCGACC
GAAGAAGACGACCGCACGCTCGTCGAACTGCTGATCGAGCAGATCGAATTCTGCGACGTGCTCGTCATCAACAAGGCGGA
TCTCGTCGACGCCGATTCGCTCGCGCGCCTGCAGCGTATCCTCGCGAACCTGAACCCGCGCGCGCGGCAAATCGTGAGCC
GCTTCGGCGACGTGCCGCTCGCCGAAGTGCTCAACACCGGCCGCTTCGATTTCGACGCGGCCGCGAACGCGCCCGGTTGG
CTTGCGTCGCTCGAGCACCGGCATGACGACGATGAAGAAGAATCCGACCGAGGCAACGGCCACGTGCATAGCGAGGCCGA
TGAATACGGCATCGGCCACTTCGTCTATCGCGCGCGCCGGCCGTTCCATCCGCAGCGGCTCTGGGCGCTGCTGCACGAAG
AATGGAAGGGCGTGCTGCGCAGCAAGGGCTTCTTCTGGCTCGCGACGCGCAATGACATCGCGGGCTCGCTGTCGCAGGCG
GGCGGCGTGTGCCGGCACGGTCCGGCAGGACACTGGTGGGCCGCGCAGGATCGCGCCGAATGGCCGGAGGCGGGCGACGA
GCTATACGACGAGATCGTCGCCGACTGGCGCGGCGATCTCGCCGACACGTCGATCGGCGATCGCCGGCAGGAGTTCGTGC
TGATCGGCGTCGGGCTCGACGCGGCGGCGTGGCGCGCGAAGTTCGACGCATGCCTGCTCACCGACGCGGAATACGCGCAA
GGCAAAGACGCGTGGGCGAACTACGCGGACCCGTTCCCGGCGTGGGACGTCGACGATCATGACCATGATCATGACGATCA
CGACCACGGCGACGACGCCGAAATCGTCCATCGCCACTGA

Upstream 100 bases:

>100_bases
GCAGGGCGCGCAAAGCGCGCAGCGCTAGCTCGCCGCGGCGCCACGCAGGCGCGCGGCCGGGCGGAACGGGCGTGAATCCG
CCGCCTGAGCGCACCAGGCG

Downstream 100 bases:

>100_bases
TCGTCAAAGATTGAAAAAGGCCATGCGGCGCGGCAAAAAAAAACGCGCCGAAAAGAAAAAACCCGCTGAAACCAGCGGGT
TTTTTGTTCGCGAACAGCTC

Product: cobalamin synthesis protein/P47K family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MQCRAGSPAIDRTACKHPRSFRYRITHHEIAAVLPPRAAVRLYLMHNAAFPPPVRAGRSPVPPRFRGAAARFPLFSLVRT
AMNQPLPVTVLSGFLGAGKTTLLNHILANRAGLKVAVIVNDLAAANVDATFVRGATELSHVEEHFVEMSNGCICCTLRDD
LLVEIRRLAAENRFDAIVIESTGIAEPMPIAETFTFVDDDGSALEDVARLDTMVTVVDAFNFLRDYARDDALAEHGLAAT
EEDDRTLVELLIEQIEFCDVLVINKADLVDADSLARLQRILANLNPRARQIVSRFGDVPLAEVLNTGRFDFDAAANAPGW
LASLEHRHDDDEEESDRGNGHVHSEADEYGIGHFVYRARRPFHPQRLWALLHEEWKGVLRSKGFFWLATRNDIAGSLSQA
GGVCRHGPAGHWWAAQDRAEWPEAGDELYDEIVADWRGDLADTSIGDRRQEFVLIGVGLDAAAWRAKFDACLLTDAEYAQ
GKDAWANYADPFPAWDVDDHDHDHDDHDHGDDAEIVHRH

Sequences:

>Translated_519_residues
MQCRAGSPAIDRTACKHPRSFRYRITHHEIAAVLPPRAAVRLYLMHNAAFPPPVRAGRSPVPPRFRGAAARFPLFSLVRT
AMNQPLPVTVLSGFLGAGKTTLLNHILANRAGLKVAVIVNDLAAANVDATFVRGATELSHVEEHFVEMSNGCICCTLRDD
LLVEIRRLAAENRFDAIVIESTGIAEPMPIAETFTFVDDDGSALEDVARLDTMVTVVDAFNFLRDYARDDALAEHGLAAT
EEDDRTLVELLIEQIEFCDVLVINKADLVDADSLARLQRILANLNPRARQIVSRFGDVPLAEVLNTGRFDFDAAANAPGW
LASLEHRHDDDEEESDRGNGHVHSEADEYGIGHFVYRARRPFHPQRLWALLHEEWKGVLRSKGFFWLATRNDIAGSLSQA
GGVCRHGPAGHWWAAQDRAEWPEAGDELYDEIVADWRGDLADTSIGDRRQEFVLIGVGLDAAAWRAKFDACLLTDAEYAQ
GKDAWANYADPFPAWDVDDHDHDHDDHDHGDDAEIVHRH
>Mature_519_residues
MQCRAGSPAIDRTACKHPRSFRYRITHHEIAAVLPPRAAVRLYLMHNAAFPPPVRAGRSPVPPRFRGAAARFPLFSLVRT
AMNQPLPVTVLSGFLGAGKTTLLNHILANRAGLKVAVIVNDLAAANVDATFVRGATELSHVEEHFVEMSNGCICCTLRDD
LLVEIRRLAAENRFDAIVIESTGIAEPMPIAETFTFVDDDGSALEDVARLDTMVTVVDAFNFLRDYARDDALAEHGLAAT
EEDDRTLVELLIEQIEFCDVLVINKADLVDADSLARLQRILANLNPRARQIVSRFGDVPLAEVLNTGRFDFDAAANAPGW
LASLEHRHDDDEEESDRGNGHVHSEADEYGIGHFVYRARRPFHPQRLWALLHEEWKGVLRSKGFFWLATRNDIAGSLSQA
GGVCRHGPAGHWWAAQDRAEWPEAGDELYDEIVADWRGDLADTSIGDRRQEFVLIGVGLDAAAWRAKFDACLLTDAEYAQ
GKDAWANYADPFPAWDVDDHDHDHDDHDHGDDAEIVHRH

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI146231952, Length=234, Percent_Identity=30.7692307692308, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI148727351, Length=234, Percent_Identity=30.3418803418803, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI126722884, Length=234, Percent_Identity=30.3418803418803, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI33469141, Length=233, Percent_Identity=30.0429184549356, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI223941779, Length=209, Percent_Identity=31.1004784688995, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI223941776, Length=217, Percent_Identity=30.4147465437788, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI119120938, Length=147, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI87082430, Length=234, Percent_Identity=32.4786324786325, Blast_Score=96, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6324356, Length=345, Percent_Identity=25.2173913043478, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 57682; Mature: 57682

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCRAGSPAIDRTACKHPRSFRYRITHHEIAAVLPPRAAVRLYLMHNAAFPPPVRAGRSP
CCCCCCCCCHHHHHHCCCCCCEEEEEHHHHHHHCCCHHHEEEEEEECCCCCCCCCCCCCC
VPPRFRGAAARFPLFSLVRTAMNQPLPVTVLSGFLGAGKTTLLNHILANRAGLKVAVIVN
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEE
DLAAANVDATFVRGATELSHVEEHFVEMSNGCICCTLRDDLLVEIRRLAAENRFDAIVIE
HHHHCCCCHHHHHCHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCCCEEEEE
STGIAEPMPIAETFTFVDDDGSALEDVARLDTMVTVVDAFNFLRDYARDDALAEHGLAAT
CCCCCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EEDDRTLVELLIEQIEFCDVLVINKADLVDADSLARLQRILANLNPRARQIVSRFGDVPL
CCCHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCH
AEVLNTGRFDFDAAANAPGWLASLEHRHDDDEEESDRGNGHVHSEADEYGIGHFVYRARR
HHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHCCCHHHHHHHCC
PFHPQRLWALLHEEWKGVLRSKGFFWLATRNDIAGSLSQAGGVCRHGPAGHWWAAQDRAE
CCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
WPEAGDELYDEIVADWRGDLADTSIGDRRQEFVLIGVGLDAAAWRAKFDACLLTDAEYAQ
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCEECCCHHHC
GKDAWANYADPFPAWDVDDHDHDHDDHDHGDDAEIVHRH
CCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MQCRAGSPAIDRTACKHPRSFRYRITHHEIAAVLPPRAAVRLYLMHNAAFPPPVRAGRSP
CCCCCCCCCHHHHHHCCCCCCEEEEEHHHHHHHCCCHHHEEEEEEECCCCCCCCCCCCCC
VPPRFRGAAARFPLFSLVRTAMNQPLPVTVLSGFLGAGKTTLLNHILANRAGLKVAVIVN
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEE
DLAAANVDATFVRGATELSHVEEHFVEMSNGCICCTLRDDLLVEIRRLAAENRFDAIVIE
HHHHCCCCHHHHHCHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCCCEEEEE
STGIAEPMPIAETFTFVDDDGSALEDVARLDTMVTVVDAFNFLRDYARDDALAEHGLAAT
CCCCCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EEDDRTLVELLIEQIEFCDVLVINKADLVDADSLARLQRILANLNPRARQIVSRFGDVPL
CCCHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCH
AEVLNTGRFDFDAAANAPGWLASLEHRHDDDEEESDRGNGHVHSEADEYGIGHFVYRARR
HHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHCCCHHHHHHHCC
PFHPQRLWALLHEEWKGVLRSKGFFWLATRNDIAGSLSQAGGVCRHGPAGHWWAAQDRAE
CCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
WPEAGDELYDEIVADWRGDLADTSIGDRRQEFVLIGVGLDAAAWRAKFDACLLTDAEYAQ
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCEECCCHHHC
GKDAWANYADPFPAWDVDDHDHDHDDHDHGDDAEIVHRH
CCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]