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The map label for this gene is speE [H]

Identifier: 83719650

GI number: 83719650

Start: 1339560

End: 1340417

Strand: Reverse

Name: speE [H]

Synonym: BTH_I1194

Alternate gene names: 83719650

Gene position: 1340417-1339560 (Counterclockwise)

Preceding gene: 83721252

Following gene: 83720950

Centisome position: 35.19

GC content: 70.05

Gene sequence:

>858_bases
TTGAGCACCACCCTCCTCTTCCACCCGACCCCCGACGTCGCCTATGGCTTCCCGAACGCCCGGAGGCTCGCGCGCATCGA
ATCCGCGCATCAGGAGATCGAGGTCTGGGAAACGTCGCTGCTCGGGCGGCTCTTCACGCTCGACGGCCGGCCGATGACGT
CGGTCGGCGACGAGTTCGTCTATCACGAATGCATGACGCATCCGGCCGCCCTCGCGCATCCGGCGCCGAGGAAGGCGCTC
GTGCTGGGCGGCGGCGACGGCGGCGCCGCGCGCCAGCTCCTGCGGCATCCGTGCATCGAGCGGATCGTCGTCGCGGAACT
CGACGCCGCCGTCGTCGACATGGCCCGCCGCTTTCTCGGCGACGTTCACCAGGGCGCGCTCGACGATCCTCGCGTCGAGC
TCGTGATCGGCGACGCCGCGCGCTACGTCGACCACGCGTGCGAGCACTTCGACCTCGCCGTATTCGACCTCACGCCGCCC
GATTCGCCGGCGGCGGGCCTGTACACGCCCAAGTTCTACACGCGCCTGAAGCGCATCCTGACGCCGCAAGGCGCGGTGTC
GCTGCATCTGGGCTCGCCGCTCTATCACGAAGCGCGCGTCGTCTCGCTGCTCGCCGGGCTGCGCGCGAGCTTCGCGGTCG
TCGCGCCGCTCTGCGCGCACGTGCCGCTGTATGGCTCGCCATGGCTGATGGCGATCGCGAGCGACGCGCTCGACGCGGCC
TCGCTGTTCTCGCACGACGTCGAGGCGCGGCTCGCCGAACGGCGCATCGAAGGCTTGCGCTTCTACGACGCGAAGCTGCA
TCCCGCGCTCTTCACGCTGCCGCACGCGCTGCGCGATACTCTCGGCATGCATCGCTAA

Upstream 100 bases:

>100_bases
GCCTTGTCGGAATCCGCCCGTGCGCACGGTTTCTCGGCCATCTCGCCACCCTCTATAATTCAGACCATCGGAACCGCCCC
GCCAGCACGCGCCCGCCGCC

Downstream 100 bases:

>100_bases
GTTCGGCGAAGCATCCGCCTTTCCCGCAGGAGAACCCGCATGACCGACCCACGGCCGGCCGACGTGCCCTGGTTGACCCC
CTATCTGACGGTGCGCAGCG

Product: spermidine synthase

Products: NA

Alternate protein names: Putrescine aminopropyltransferase; PAPT; SPDSY [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MSTTLLFHPTPDVAYGFPNARRLARIESAHQEIEVWETSLLGRLFTLDGRPMTSVGDEFVYHECMTHPAALAHPAPRKAL
VLGGGDGGAARQLLRHPCIERIVVAELDAAVVDMARRFLGDVHQGALDDPRVELVIGDAARYVDHACEHFDLAVFDLTPP
DSPAAGLYTPKFYTRLKRILTPQGAVSLHLGSPLYHEARVVSLLAGLRASFAVVAPLCAHVPLYGSPWLMAIASDALDAA
SLFSHDVEARLAERRIEGLRFYDAKLHPALFTLPHALRDTLGMHR

Sequences:

>Translated_285_residues
MSTTLLFHPTPDVAYGFPNARRLARIESAHQEIEVWETSLLGRLFTLDGRPMTSVGDEFVYHECMTHPAALAHPAPRKAL
VLGGGDGGAARQLLRHPCIERIVVAELDAAVVDMARRFLGDVHQGALDDPRVELVIGDAARYVDHACEHFDLAVFDLTPP
DSPAAGLYTPKFYTRLKRILTPQGAVSLHLGSPLYHEARVVSLLAGLRASFAVVAPLCAHVPLYGSPWLMAIASDALDAA
SLFSHDVEARLAERRIEGLRFYDAKLHPALFTLPHALRDTLGMHR
>Mature_284_residues
STTLLFHPTPDVAYGFPNARRLARIESAHQEIEVWETSLLGRLFTLDGRPMTSVGDEFVYHECMTHPAALAHPAPRKALV
LGGGDGGAARQLLRHPCIERIVVAELDAAVVDMARRFLGDVHQGALDDPRVELVIGDAARYVDHACEHFDLAVFDLTPPD
SPAAGLYTPKFYTRLKRILTPQGAVSLHLGSPLYHEARVVSLLAGLRASFAVVAPLCAHVPLYGSPWLMAIASDALDAAS
LFSHDVEARLAERRIEGLRFYDAKLHPALFTLPHALRDTLGMHR

Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor [H]

COG id: COG0421

COG function: function code E; Spermidine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spermidine/spermine synthase family [H]

Homologues:

Organism=Homo sapiens, GI63253298, Length=256, Percent_Identity=26.953125, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1786312, Length=284, Percent_Identity=33.0985915492958, Blast_Score=161, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI25154106, Length=273, Percent_Identity=29.3040293040293, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI212645616, Length=323, Percent_Identity=25.6965944272446, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323175, Length=253, Percent_Identity=28.0632411067194, Blast_Score=139, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6325326, Length=250, Percent_Identity=26.8, Blast_Score=122, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24645443, Length=273, Percent_Identity=28.9377289377289, Blast_Score=131, Evalue=4e-31,
Organism=Drosophila melanogaster, GI21355941, Length=212, Percent_Identity=29.7169811320755, Blast_Score=105, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001045 [H]

Pfam domain/function: PF01564 Spermine_synth [H]

EC number: =2.5.1.16 [H]

Molecular weight: Translated: 31227; Mature: 31096

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS51006 SPERMIDINE_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTLLFHPTPDVAYGFPNARRLARIESAHQEIEVWETSLLGRLFTLDGRPMTSVGDEFV
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHH
YHECMTHPAALAHPAPRKALVLGGGDGGAARQLLRHPCIERIVVAELDAAVVDMARRFLG
HHHHHCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVHQGALDDPRVELVIGDAARYVDHACEHFDLAVFDLTPPDSPAAGLYTPKFYTRLKRIL
HHHCCCCCCCCEEEEECHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHH
TPQGAVSLHLGSPLYHEARVVSLLAGLRASFAVVAPLCAHVPLYGSPWLMAIASDALDAA
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
SLFSHDVEARLAERRIEGLRFYDAKLHPALFTLPHALRDTLGMHR
HHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STTLLFHPTPDVAYGFPNARRLARIESAHQEIEVWETSLLGRLFTLDGRPMTSVGDEFV
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHH
YHECMTHPAALAHPAPRKALVLGGGDGGAARQLLRHPCIERIVVAELDAAVVDMARRFLG
HHHHHCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVHQGALDDPRVELVIGDAARYVDHACEHFDLAVFDLTPPDSPAAGLYTPKFYTRLKRIL
HHHCCCCCCCCEEEEECHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHH
TPQGAVSLHLGSPLYHEARVVSLLAGLRASFAVVAPLCAHVPLYGSPWLMAIASDALDAA
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
SLFSHDVEARLAERRIEGLRFYDAKLHPALFTLPHALRDTLGMHR
HHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]