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The map label for this gene is lpxA [H]

Identifier: 83719622

GI number: 83719622

Start: 3661273

End: 3661932

Strand: Direct

Name: lpxA [H]

Synonym: BTH_I3214

Alternate gene names: 83719622

Gene position: 3661273-3661932 (Clockwise)

Preceding gene: 83718558

Following gene: 83720742

Centisome position: 96.12

GC content: 61.06

Gene sequence:

>660_bases
ATGGCAAACGTCGTTCTATTCGGCTTGCAGGATTACGCGGAGCTCGCGCATTACTATCTGGAGCACGACTCGCCCCACCA
AGTCGCCGCGTTCTGCGTGGACCGGCAGTACATTCCCGACAGCGGAACGTTCAAGAACCTGCCCGTCGTCGCGTTCGAGG
ACGTCGCGCACACGCATCCGCCGGGCGACTTCAGCTTCTTCGCGCCGATGTCGCCGAAGCACATGAATCGCGATCGCGAG
CGGATCTTCAACGCGATCAAGGCGCACGGCTACACATTGATCAGCTACGTCAGCTCGAGAGCGACGAAGTTCGATAACGA
GATCGGCGAGAACTGCTTCATCCTCGAGGACAACACGCTGCAGCCGTTCACCCGGATCGGCGACAACGTCGTGCTGTGGA
GCGGCAACCACATTGGGCACCACGGACGCATCGGCGATCACGTGACGATGACCTCGCACGTTGTCATGTCCGGCCATTGC
GACATCGGCGCGTACAGCTTCGTCGGCGTCAACGCGACGCTGCGCGACGGCGTGACGATCGGAGAAGGCACGTTCGTCGC
GATGGCATCGGCGATCACGAAGAACACCGAGCCGTGGTCGGTCTATCGCGGCAATCCGGCAGTCAAGCTGACGATGCCGA
GCACGGAAGTCAAGTTCTAG

Upstream 100 bases:

>100_bases
TCACGCACTTCGTCGCGGCTGAGCTGTCACGGCACTATGTCGTGCGGCACGACTACGGGCTGTACGAGTACACGACCTAT
GTGTACAGGGAGCACAACTG

Downstream 100 bases:

>100_bases
GACAACCGAGATGGCGGGTATTCACTGGGAAAAACGCGGGCTCGTCTACACGGTCGATGCGCGGTTGCCGTGGGCGACAT
CGCATGCGCAGATTCCGACC

Product: transferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MANVVLFGLQDYAELAHYYLEHDSPHQVAAFCVDRQYIPDSGTFKNLPVVAFEDVAHTHPPGDFSFFAPMSPKHMNRDRE
RIFNAIKAHGYTLISYVSSRATKFDNEIGENCFILEDNTLQPFTRIGDNVVLWSGNHIGHHGRIGDHVTMTSHVVMSGHC
DIGAYSFVGVNATLRDGVTIGEGTFVAMASAITKNTEPWSVYRGNPAVKLTMPSTEVKF

Sequences:

>Translated_219_residues
MANVVLFGLQDYAELAHYYLEHDSPHQVAAFCVDRQYIPDSGTFKNLPVVAFEDVAHTHPPGDFSFFAPMSPKHMNRDRE
RIFNAIKAHGYTLISYVSSRATKFDNEIGENCFILEDNTLQPFTRIGDNVVLWSGNHIGHHGRIGDHVTMTSHVVMSGHC
DIGAYSFVGVNATLRDGVTIGEGTFVAMASAITKNTEPWSVYRGNPAVKLTMPSTEVKF
>Mature_218_residues
ANVVLFGLQDYAELAHYYLEHDSPHQVAAFCVDRQYIPDSGTFKNLPVVAFEDVAHTHPPGDFSFFAPMSPKHMNRDRER
IFNAIKAHGYTLISYVSSRATKFDNEIGENCFILEDNTLQPFTRIGDNVVLWSGNHIGHHGRIGDHVTMTSHVVMSGHCD
IGAYSFVGVNATLRDGVTIGEGTFVAMASAITKNTEPWSVYRGNPAVKLTMPSTEVKF

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 24307; Mature: 24175

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANVVLFGLQDYAELAHYYLEHDSPHQVAAFCVDRQYIPDSGTFKNLPVVAFEDVAHTHP
CCCEEEECHHHHHHHHHHHHCCCCCHHEEEEEECCCCCCCCCCCCCCCEEEEECHHCCCC
PGDFSFFAPMSPKHMNRDRERIFNAIKAHGYTLISYVSSRATKFDNEIGENCFILEDNTL
CCCEEEECCCCHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCC
QPFTRIGDNVVLWSGNHIGHHGRIGDHVTMTSHVVMSGHCDIGAYSFVGVNATLRDGVTI
CHHHHCCCEEEEECCCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEEEECCEEHHCCEEE
GEGTFVAMASAITKNTEPWSVYRGNPAVKLTMPSTEVKF
CCCHHHHHHHHHHCCCCCCEEEECCCEEEEEECCCCCCC
>Mature Secondary Structure 
ANVVLFGLQDYAELAHYYLEHDSPHQVAAFCVDRQYIPDSGTFKNLPVVAFEDVAHTHP
CCEEEECHHHHHHHHHHHHCCCCCHHEEEEEECCCCCCCCCCCCCCCEEEEECHHCCCC
PGDFSFFAPMSPKHMNRDRERIFNAIKAHGYTLISYVSSRATKFDNEIGENCFILEDNTL
CCCEEEECCCCHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCC
QPFTRIGDNVVLWSGNHIGHHGRIGDHVTMTSHVVMSGHCDIGAYSFVGVNATLRDGVTI
CHHHHCCCEEEEECCCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEEEECCEEHHCCEEE
GEGTFVAMASAITKNTEPWSVYRGNPAVKLTMPSTEVKF
CCCHHHHHHHHHHCCCCCCEEEECCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA