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The map label for this gene is argG [H]

Identifier: 83719506

GI number: 83719506

Start: 312089

End: 313429

Strand: Direct

Name: argG [H]

Synonym: BTH_I0279

Alternate gene names: 83719506

Gene position: 312089-313429 (Clockwise)

Preceding gene: 83720967

Following gene: 83721022

Centisome position: 8.19

GC content: 65.4

Gene sequence:

>1341_bases
ATGACCACGATTCTTGAAAATCTCCCGGCCGGCCAGAAAGTCGGCATCGCGTTCTCCGGCGGGCTCGACACGAGCGCCGC
GCTGCACTGGATGCGCATCAAGGGGGCCGTTCCTTACGCGTACACGGCCAATCTCGGCCAGCCCGACGAAGACGACTACG
ATGCGATCCCGAAGCGCGCGATCCAGTACGGCGCCGAGGGCGCACGCCTGATTGACTGCCGCGCGCAGCTCGTGGCCGAA
GGGATCGCGGCGCTCCAGTGCGGCGCGTTCCACATCTCGACGGCCGGCGTCACGTATTTCAATACGACCCCGATTGGCCG
CGCCGTGACGGGCACGATGCTCGTCGCCGCGATGAAGGAGGACGGCGTCAACATCTGGGGCGACGGCAGCACGTACAAGG
GCAACGACATCGAGCGCTTCTACCGCTACGGCCTGCTCGTCAATCCGGATCTGAAGATCTACAAGCCGTGGCTCGATCAG
CAGTTCATCGACGAGCTGGGCGGCCGCGCGGAAATGTCCGAATTCATGCGCCAGGCCGGCTTCGAGTACAAGATGTCGGC
GGAGAAGGCGTATTCGACCGATTCGAACCTGCTGGGCGCGACGCACGAGGCGAAGGATCTCGAGAGCCTCGAGAGCGGCA
TCAAGATCGTCAATCCGATCATGGGCGTCGCGTTCTGGCGCGACGACGTGAAGATCGACAAGGAAGCGGTGACGGTCCGC
TTCGAAGAGGGCCGCCCCGTCGCGCTGAACGGCGTCGAGTACAAGGATGCGGTCGAGCTGCTGCTCGAGGCGAACCGGAT
CGGCGGCCGCCACGGCCTCGGGATGAGCGACCAGATCGAGAACCGGATCATCGAGGCGAAGAGCCGCGGCATCTATGAAG
CCCCGGGGCTTGCACTGCTGTACATCGCGTACGAGCGCCTCGTCACCGGCATCCACAACGAAGACACGATCGAGCAGTAC
CGCGAGAACGGCCGCCGCCTCGGCCGCCTGCTGTACCAGGGCCGCTGGTTCGATCCGCAGGCGATCATGCTGCGCGAGAC
CGCGCAGCGCTGGGTCGCGCGCGCGGTCACGGGCGAGGTGACGGTCGAGCTGCGCCGCGGCAACGACTATTCGATTCTCG
CCACGCGCTCGCCGAACCTGACGTACCAGCCGGAGCGCCTGTCGATGGAGAAGGTGCAGTCGACGTTCTCGCCGCGCGAC
CGGATCGGCCAGTTGACGATGCGCAACCTCGACATCACCGACACCCGCGACAAGCTGCGCATCTACTCGGAAGTCGGCCT
GCTCACGCCGGGCGAATCGTCGGCGCTGCCGAAGCTGAAGGAAGACGAGAGCGGCAACTGA

Upstream 100 bases:

>100_bases
CCGCCGGAGCAGTGCGTGAGACTTGCCTCATAATCAGGCACAGCCGATACTCTTGGATTCCGCGAAATTCCCCCTTCCAA
CTGATTGAACGGTTTTCGTC

Downstream 100 bases:

>100_bases
CGCGCCCGCGTCCGGATGTCCTGACGTCCGCTCGGCGCCGCGCGCGGCCGTGCGCGAACCGGTGTTCGCGCCCGGCTGCG
GCAGCGCAGGCCGGACGGCC

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MTTILENLPAGQKVGIAFSGGLDTSAALHWMRIKGAVPYAYTANLGQPDEDDYDAIPKRAIQYGAEGARLIDCRAQLVAE
GIAALQCGAFHISTAGVTYFNTTPIGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLVNPDLKIYKPWLDQ
QFIDELGGRAEMSEFMRQAGFEYKMSAEKAYSTDSNLLGATHEAKDLESLESGIKIVNPIMGVAFWRDDVKIDKEAVTVR
FEEGRPVALNGVEYKDAVELLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALLYIAYERLVTGIHNEDTIEQY
RENGRRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEVTVELRRGNDYSILATRSPNLTYQPERLSMEKVQSTFSPRD
RIGQLTMRNLDITDTRDKLRIYSEVGLLTPGESSALPKLKEDESGN

Sequences:

>Translated_446_residues
MTTILENLPAGQKVGIAFSGGLDTSAALHWMRIKGAVPYAYTANLGQPDEDDYDAIPKRAIQYGAEGARLIDCRAQLVAE
GIAALQCGAFHISTAGVTYFNTTPIGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLVNPDLKIYKPWLDQ
QFIDELGGRAEMSEFMRQAGFEYKMSAEKAYSTDSNLLGATHEAKDLESLESGIKIVNPIMGVAFWRDDVKIDKEAVTVR
FEEGRPVALNGVEYKDAVELLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALLYIAYERLVTGIHNEDTIEQY
RENGRRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEVTVELRRGNDYSILATRSPNLTYQPERLSMEKVQSTFSPRD
RIGQLTMRNLDITDTRDKLRIYSEVGLLTPGESSALPKLKEDESGN
>Mature_445_residues
TTILENLPAGQKVGIAFSGGLDTSAALHWMRIKGAVPYAYTANLGQPDEDDYDAIPKRAIQYGAEGARLIDCRAQLVAEG
IAALQCGAFHISTAGVTYFNTTPIGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLVNPDLKIYKPWLDQQ
FIDELGGRAEMSEFMRQAGFEYKMSAEKAYSTDSNLLGATHEAKDLESLESGIKIVNPIMGVAFWRDDVKIDKEAVTVRF
EEGRPVALNGVEYKDAVELLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALLYIAYERLVTGIHNEDTIEQYR
ENGRRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEVTVELRRGNDYSILATRSPNLTYQPERLSMEKVQSTFSPRDR
IGQLTMRNLDITDTRDKLRIYSEVGLLTPGESSALPKLKEDESGN

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=408, Percent_Identity=29.4117647058824, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI16950633, Length=408, Percent_Identity=29.4117647058824, Blast_Score=156, Evalue=4e-38,
Organism=Escherichia coli, GI1789563, Length=444, Percent_Identity=78.3783783783784, Blast_Score=732, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6324514, Length=417, Percent_Identity=29.0167865707434, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI21358151, Length=424, Percent_Identity=29.4811320754717, Blast_Score=167, Evalue=2e-41,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 49725; Mature: 49594

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTILENLPAGQKVGIAFSGGLDTSAALHWMRIKGAVPYAYTANLGQPDEDDYDAIPKRA
CCCCHHHCCCCCEEEEEEECCCCHHHHEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHH
IQYGAEGARLIDCRAQLVAEGIAALQCGAFHISTAGVTYFNTTPIGRAVTGTMLVAAMKE
HHHCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCHHHHHHHHHEEHHC
DGVNIWGDGSTYKGNDIERFYRYGLLVNPDLKIYKPWLDQQFIDELGGRAEMSEFMRQAG
CCCEEECCCCCCCCCHHHHHHHCCCEECCCCEEECCCCCHHHHHHHCCHHHHHHHHHHCC
FEYKMSAEKAYSTDSNLLGATHEAKDLESLESGIKIVNPIMGVAFWRDDVKIDKEAVTVR
CCEEECHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCEEEEEE
FEEGRPVALNGVEYKDAVELLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALL
ECCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHH
YIAYERLVTGIHNEDTIEQYRENGRRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCEE
TVELRRGNDYSILATRSPNLTYQPERLSMEKVQSTFSPRDRIGQLTMRNLDITDTRDKLR
EEEEECCCCEEEEEECCCCCEECHHHHHHHHHHHHCCCHHHHHHHEEECCCCCCCHHHHH
IYSEVGLLTPGESSALPKLKEDESGN
HHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTILENLPAGQKVGIAFSGGLDTSAALHWMRIKGAVPYAYTANLGQPDEDDYDAIPKRA
CCCHHHCCCCCEEEEEEECCCCHHHHEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHH
IQYGAEGARLIDCRAQLVAEGIAALQCGAFHISTAGVTYFNTTPIGRAVTGTMLVAAMKE
HHHCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCHHHHHHHHHEEHHC
DGVNIWGDGSTYKGNDIERFYRYGLLVNPDLKIYKPWLDQQFIDELGGRAEMSEFMRQAG
CCCEEECCCCCCCCCHHHHHHHCCCEECCCCEEECCCCCHHHHHHHCCHHHHHHHHHHCC
FEYKMSAEKAYSTDSNLLGATHEAKDLESLESGIKIVNPIMGVAFWRDDVKIDKEAVTVR
CCEEECHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCEEEEEE
FEEGRPVALNGVEYKDAVELLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALL
ECCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHH
YIAYERLVTGIHNEDTIEQYRENGRRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCEE
TVELRRGNDYSILATRSPNLTYQPERLSMEKVQSTFSPRDRIGQLTMRNLDITDTRDKLR
EEEEECCCCEEEEEECCCCCEECHHHHHHHHHHHHCCCHHHHHHHEEECCCCCCCHHHHH
IYSEVGLLTPGESSALPKLKEDESGN
HHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA