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The map label for this gene is ttuB [H]

Identifier: 83719387

GI number: 83719387

Start: 999440

End: 1000747

Strand: Reverse

Name: ttuB [H]

Synonym: BTH_I0875

Alternate gene names: 83719387

Gene position: 1000747-999440 (Counterclockwise)

Preceding gene: 83720260

Following gene: 83719610

Centisome position: 26.27

GC content: 67.58

Gene sequence:

>1308_bases
ATGGCCCGTACCATGCCGGCGGCCACGCCGGGCGCGCCGTCCGCTTTCGAGGCGGCCACTTATCGCAAGGTTTCGTGGCG
TCTCGCGCCGCTCCTGCTGCTCTGCTACGTGGTCGCGTATCTCGACCGCGTGAACGTCGGCTTCGCGAAACTGCAGATGG
CGTCCGACCTGCACCTGTCCGACGCGGTCTACGGCCTCGGCGCGGGCATCTTCTTCGTCGGCTACTTTCTGTTCGAAGTG
CCGAGCAACGTGATCCTGCACAAGGTGGGCGCGCGCGTGTGGATCGCGCGGATCATGGTCACGTGGGGCATCATCTCGGC
GCTGACGATGTTCGTGTCGACGCCCGCGATGTTCTACACGATGCGCTTTCTGCTCGGCGTCGCGGAAGCCGGCTTCTTCC
CCGGCGTGATTCTCTACCTGACCTACTGGTATCCGGCGCACCGCCGCGGCCGGATGACGACGCTCTTCATGACGGCCGTC
GCGCTGTCGGGCGTCATCGGCGGCCCGATCTCCGGCTACATCCTGAAGACTTTCGACGGCGCGAACGGCTGGCAGGGCTG
GCAGTGGCTGTTCCTGCTCGAAGGCGTGCCGTCGATGCTCGTCGGCATCCTGCTGCTGTTCGCGCTCGACGACGGGATCG
CGAAGGCGAAATGGCTCGACGACGACGAGAAAGCGCTGCTGTCGCGCAACGTCGCCGCCGAGGAGGCGCGCAAGGAGGAC
CTGCCGCTTTCCGTCGTGTTCACGAGCCCGCGCGTATGGCTGATGGGTCTCATCTACTTCTCGTTCGTGATGGGGCTCTA
CGGCGTCGGCTTCTGGCTGCCGACGATCATCAAGTCGACGGGCGTGACCGACGCGTTCTCGATCGGCCTTCTGTCCGCGG
TGCCGTACGCGGCGGCCGTCGTCGCGATGCTCGTGACCGCGCACAGCGCGGACCGCCGCCGCGAGCGGCGCTGGCACCTC
GCGATTCCGGCGGCGGCGGGCGCGCTCGGGCTCGTGCTGTCGGTCGTCTGGGCGCACGACACGGCGCTCGCCATGCTCGG
CCTGACGATCGGGACGATGGGCATCCTGACGACGCTGCCGCTCTTCTGGAGCCTGCCGACCGCATTCCTCGGCGGCACGG
CCGCCGCGGCGGGCATCGCGATCATCAATTCGGTCGGCAACCTCGCGGGCTTCCTGAGCCCGTATCTCGTCGGCTGGCTC
AAGCAGGCGAGCGCATCGAACGACGCGGGAATGTACATGCTCGCCGGGTTCCTCGTGCTGGGCGGGCTGCTCGCGCTCAC
GGTGCCGAAGTCGCTCGTCGACATCTGA

Upstream 100 bases:

>100_bases
TCCGACGAAGCCGCGTTCGTCACCGGCATCTGCGTCGAGGTCGACGGCGGCCGCTGCGTCTGAGCGCCGAACACTAGACA
ACACACCAGAGGAGACAGTC

Downstream 100 bases:

>100_bases
TTCGATACTCGGCCCTCGATACGCGTTGCGGCACCCCAACGAAAACGGCGGCCGTCGAGGCCGCCGTTTTTTCGATTCCA
CCGCCTGCCGTCGCGCATCA

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MARTMPAATPGAPSAFEAATYRKVSWRLAPLLLLCYVVAYLDRVNVGFAKLQMASDLHLSDAVYGLGAGIFFVGYFLFEV
PSNVILHKVGARVWIARIMVTWGIISALTMFVSTPAMFYTMRFLLGVAEAGFFPGVILYLTYWYPAHRRGRMTTLFMTAV
ALSGVIGGPISGYILKTFDGANGWQGWQWLFLLEGVPSMLVGILLLFALDDGIAKAKWLDDDEKALLSRNVAAEEARKED
LPLSVVFTSPRVWLMGLIYFSFVMGLYGVGFWLPTIIKSTGVTDAFSIGLLSAVPYAAAVVAMLVTAHSADRRRERRWHL
AIPAAAGALGLVLSVVWAHDTALAMLGLTIGTMGILTTLPLFWSLPTAFLGGTAAAAGIAIINSVGNLAGFLSPYLVGWL
KQASASNDAGMYMLAGFLVLGGLLALTVPKSLVDI

Sequences:

>Translated_435_residues
MARTMPAATPGAPSAFEAATYRKVSWRLAPLLLLCYVVAYLDRVNVGFAKLQMASDLHLSDAVYGLGAGIFFVGYFLFEV
PSNVILHKVGARVWIARIMVTWGIISALTMFVSTPAMFYTMRFLLGVAEAGFFPGVILYLTYWYPAHRRGRMTTLFMTAV
ALSGVIGGPISGYILKTFDGANGWQGWQWLFLLEGVPSMLVGILLLFALDDGIAKAKWLDDDEKALLSRNVAAEEARKED
LPLSVVFTSPRVWLMGLIYFSFVMGLYGVGFWLPTIIKSTGVTDAFSIGLLSAVPYAAAVVAMLVTAHSADRRRERRWHL
AIPAAAGALGLVLSVVWAHDTALAMLGLTIGTMGILTTLPLFWSLPTAFLGGTAAAAGIAIINSVGNLAGFLSPYLVGWL
KQASASNDAGMYMLAGFLVLGGLLALTVPKSLVDI
>Mature_434_residues
ARTMPAATPGAPSAFEAATYRKVSWRLAPLLLLCYVVAYLDRVNVGFAKLQMASDLHLSDAVYGLGAGIFFVGYFLFEVP
SNVILHKVGARVWIARIMVTWGIISALTMFVSTPAMFYTMRFLLGVAEAGFFPGVILYLTYWYPAHRRGRMTTLFMTAVA
LSGVIGGPISGYILKTFDGANGWQGWQWLFLLEGVPSMLVGILLLFALDDGIAKAKWLDDDEKALLSRNVAAEEARKEDL
PLSVVFTSPRVWLMGLIYFSFVMGLYGVGFWLPTIIKSTGVTDAFSIGLLSAVPYAAAVVAMLVTAHSADRRRERRWHLA
IPAAAGALGLVLSVVWAHDTALAMLGLTIGTMGILTTLPLFWSLPTAFLGGTAAAAGIAIINSVGNLAGFLSPYLVGWLK
QASASNDAGMYMLAGFLVLGGLLALTVPKSLVDI

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=349, Percent_Identity=21.7765042979943, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87082071, Length=416, Percent_Identity=36.7788461538462, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI2367379, Length=316, Percent_Identity=24.0506329113924, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1789152, Length=426, Percent_Identity=22.3004694835681, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789515, Length=419, Percent_Identity=22.673031026253, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87082320, Length=414, Percent_Identity=21.256038647343, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321698, Length=352, Percent_Identity=23.2954545454545, Blast_Score=93, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6322025, Length=264, Percent_Identity=25.7575757575758, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319876, Length=323, Percent_Identity=23.2198142414861, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324410, Length=150, Percent_Identity=24, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322612, Length=224, Percent_Identity=25, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319250, Length=221, Percent_Identity=22.6244343891403, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24584153, Length=355, Percent_Identity=22.5352112676056, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24648416, Length=308, Percent_Identity=23.3766233766234, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356189, Length=308, Percent_Identity=23.3766233766234, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24653727, Length=401, Percent_Identity=21.1970074812968, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24655271, Length=447, Percent_Identity=23.7136465324385, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI20130135, Length=447, Percent_Identity=23.7136465324385, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24583789, Length=370, Percent_Identity=23.7837837837838, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20130167, Length=429, Percent_Identity=21.4452214452214, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46807; Mature: 46676

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00778 HIS_ACID_PHOSPHAT_2 ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCHHHHCC
>Mature Secondary Structure 
ARTMPAATPGAPSAFEAATYRKVSWRLAPLLLLCYVVAYLDRVNVGFAKLQMASDLHLS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHH
DAVYGLGAGIFFVGYFLFEVPSNVILHKVGARVWIARIMVTWGIISALTMFVSTPAMFYT
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
MRFLLGVAEAGFFPGVILYLTYWYPAHRRGRMTTLFMTAVALSGVIGGPISGYILKTFDG
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECC
ANGWQGWQWLFLLEGVPSMLVGILLLFALDDGIAKAKWLDDDEKALLSRNVAAEEARKED
CCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHCHHHHHHHHCC
LPLSVVFTSPRVWLMGLIYFSFVMGLYGVGFWLPTIIKSTGVTDAFSIGLLSAVPYAAAV
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VAMLVTAHSADRRRERRWHLAIPAAAGALGLVLSVVWAHDTALAMLGLTIGTMGILTTLP
HHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFWSLPTAFLGGTAAAAGIAIINSVGNLAGFLSPYLVGWLKQASASNDAGMYMLAGFLVL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
GGLLALTVPKSLVDI
HHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8672817 [H]