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The map label for this gene is ung [H]

Identifier: 83719304

GI number: 83719304

Start: 3349074

End: 3349889

Strand: Direct

Name: ung [H]

Synonym: BTH_I2914

Alternate gene names: 83719304

Gene position: 3349074-3349889 (Clockwise)

Preceding gene: 83718843

Following gene: 83721026

Centisome position: 87.92

GC content: 69.49

Gene sequence:

>816_bases
ATGACCAAGCCCTCTTCGTCCCGCCCGATGCAACAACCCTCGCTGTTCGACGATCCTGCTCCGCCCGCGCCGCCGGCCCC
GAAGGGCGACGCATTCACGCCCACCCTCGAATCGCAATTCGACGCGTTGCCGCCCGACTGGCGCGCGATTCTCGAGCCGT
TCGTCGCGAGCGACGCCTATGCGCCGCTCTGCCGCTTCGTCGACGGCGAGCGTGCGGCCGGCAAGGCGATTTATCCGGCC
GACGTGTTCCGCGCGCTGCGGCTCACGCATCCGGACGACGTGAAGGTCGTGATTCTCGGCCAGGACCCGTATCACGGCGA
GGACCGCGGCATCCCGCAGGCGCACGGGCTCGCGTTCTCGGTGCCGCCCGGCGTGCGGCCGCCGCCGTCGCTGCGCAACA
TCTTCAAGGAAATCTCGGCCGACTTCGGCTATGAAGCGCCCCGCCACGGCTGTCTCGACACCTGGGCGAGCCAGGGCGTG
CTGCTGCTCAACACGGTGCTGACCGTCGAGCGCTCGTCGGCCGCGAGCCACGCGAAGCGCGGCTGGGAAAAATGCACCGA
CACGCTGATCCACGAACTCGCGACACGCCACCGCCACCTCGTGTTCATGCTGTGGGGCGCGCACGCGCAGGCAAAGCGCG
CGCTATTCGATCCGCGCGAGCACTGCGTGCTCGAAGCGCCGCATCCGTCGCCGCTGTCCGCGCACCGCGGCTTCCTCGGC
TGCCGTCATTTCGCGCTCGCGAACGACTATCTCGTCAAACACGGGCGCGCGCCGATCGACTGGCGGCTGCCGGACGCAGC
CGAGACGCTCGCCTGA

Upstream 100 bases:

>100_bases
CAGCGCTGCCGGGCGTCGCGCCGGACAACCTGAGCAAGGCGCAGCGCGGCTATCGGCTGCGCGGCGGCGACCTGCGCACC
GACTGACCGCCCTTTTCCGC

Downstream 100 bases:

>100_bases
CGCTCGACGCCGGACCGTTTCGGCGAAACAGCCCGCCGCGCGCGATTCCGCTCGCGCCACGTGAAAAGGACGTGCCCCAG
GCCCAAGTGCATCGCGCGGC

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MTKPSSSRPMQQPSLFDDPAPPAPPAPKGDAFTPTLESQFDALPPDWRAILEPFVASDAYAPLCRFVDGERAAGKAIYPA
DVFRALRLTHPDDVKVVILGQDPYHGEDRGIPQAHGLAFSVPPGVRPPPSLRNIFKEISADFGYEAPRHGCLDTWASQGV
LLLNTVLTVERSSAASHAKRGWEKCTDTLIHELATRHRHLVFMLWGAHAQAKRALFDPREHCVLEAPHPSPLSAHRGFLG
CRHFALANDYLVKHGRAPIDWRLPDAAETLA

Sequences:

>Translated_271_residues
MTKPSSSRPMQQPSLFDDPAPPAPPAPKGDAFTPTLESQFDALPPDWRAILEPFVASDAYAPLCRFVDGERAAGKAIYPA
DVFRALRLTHPDDVKVVILGQDPYHGEDRGIPQAHGLAFSVPPGVRPPPSLRNIFKEISADFGYEAPRHGCLDTWASQGV
LLLNTVLTVERSSAASHAKRGWEKCTDTLIHELATRHRHLVFMLWGAHAQAKRALFDPREHCVLEAPHPSPLSAHRGFLG
CRHFALANDYLVKHGRAPIDWRLPDAAETLA
>Mature_270_residues
TKPSSSRPMQQPSLFDDPAPPAPPAPKGDAFTPTLESQFDALPPDWRAILEPFVASDAYAPLCRFVDGERAAGKAIYPAD
VFRALRLTHPDDVKVVILGQDPYHGEDRGIPQAHGLAFSVPPGVRPPPSLRNIFKEISADFGYEAPRHGCLDTWASQGVL
LLNTVLTVERSSAASHAKRGWEKCTDTLIHELATRHRHLVFMLWGAHAQAKRALFDPREHCVLEAPHPSPLSAHRGFLGC
RHFALANDYLVKHGRAPIDWRLPDAAETLA

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=219, Percent_Identity=48.8584474885845, Blast_Score=197, Evalue=9e-51,
Organism=Homo sapiens, GI6224979, Length=220, Percent_Identity=48.6363636363636, Blast_Score=196, Evalue=2e-50,
Organism=Escherichia coli, GI1788934, Length=228, Percent_Identity=53.5087719298246, Blast_Score=224, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17556304, Length=219, Percent_Identity=42.9223744292237, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6323620, Length=222, Percent_Identity=43.2432432432432, Blast_Score=156, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 29841; Mature: 29710

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPSSSRPMQQPSLFDDPAPPAPPAPKGDAFTPTLESQFDALPPDWRAILEPFVASDAY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCHH
APLCRFVDGERAAGKAIYPADVFRALRLTHPDDVKVVILGQDPYHGEDRGIPQAHGLAFS
HHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHCCEEEE
VPPGVRPPPSLRNIFKEISADFGYEAPRHGCLDTWASQGVLLLNTVLTVERSSAASHAKR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEEEHHHHHHHHHHHHHHHHH
GWEKCTDTLIHELATRHRHLVFMLWGAHAQAKRALFDPREHCVLEAPHPSPLSAHRGFLG
HHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHCCCHHHEEEECCCCCCHHHHHHHHH
CRHFALANDYLVKHGRAPIDWRLPDAAETLA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHCC
>Mature Secondary Structure 
TKPSSSRPMQQPSLFDDPAPPAPPAPKGDAFTPTLESQFDALPPDWRAILEPFVASDAY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCHH
APLCRFVDGERAAGKAIYPADVFRALRLTHPDDVKVVILGQDPYHGEDRGIPQAHGLAFS
HHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHCCEEEE
VPPGVRPPPSLRNIFKEISADFGYEAPRHGCLDTWASQGVLLLNTVLTVERSSAASHAKR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEEEHHHHHHHHHHHHHHHHH
GWEKCTDTLIHELATRHRHLVFMLWGAHAQAKRALFDPREHCVLEAPHPSPLSAHRGFLG
HHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHCCCHHHEEEECCCCCCHHHHHHHHH
CRHFALANDYLVKHGRAPIDWRLPDAAETLA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA