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The map label for this gene is mmlH [H]

Identifier: 83719251

GI number: 83719251

Start: 3064530

End: 3065819

Strand: Direct

Name: mmlH [H]

Synonym: BTH_I2684

Alternate gene names: 83719251

Gene position: 3064530-3065819 (Clockwise)

Preceding gene: 83720696

Following gene: 83720023

Centisome position: 80.45

GC content: 67.52

Gene sequence:

>1290_bases
GTGAGCTGGTACAAAGAAATATCGCCCGTAGAAAGACGCACGTTCAAAGGATGTTTTTCCGGCTGGGCACTCGACGGCGT
CGATACGCAGATGTTCAGCCTCGTGATTCCCGCGCTGCTCACATCCTGGGGCATCGGCAAGGGGCAGGCGGGGCTGATCG
GCGGCGCGACGCTCGCCGCGGGCGCGATCGGCGGCCTGCTCGCCGGCATGATCGCCGATCGCTTCGGCCGCGTGCGCGCG
CTGCAGATCACCGTGTGCTGGTTCTCGCTGTTCACGTTCCTCAGCGCATTCGCGCAGAACTTCGAGCAATTGCTGGTGCT
GAAAACCCTGCAAGGGATCGGCTTCGGCGGCGAGTGGACGGCAGGCGCCGTGCTGTTGAGCGAAACGGTTCGCGCGCAGC
ATCGCGGCAAGGCGATGGGAATCGTGCAGAGCGCATGGGGCTTCGGCTGGGGCGGCGCGGTGCTGCTCTACACGCTCGTC
TTCTCGTGGCTGCCGCCCGAATGGGCGTGGCGCGCGCTGTTCGCGATCGGCGTGCTGCCCGCGCTGCTCGTGCTGTACAT
CCGGCGCGCCATTCCCGAGCCGCCGCGCGACGACGCGCGCGCGGCCACGTCGGCTTCATCCACGTCGGCCATGTCGGCCG
CGTCGGCACGCTCGTCGGCGAAGGGCATCTTCGATCCGTCGGTGCTCAGGATGACGATCGTCGGCGGCCTGATCGGCGTC
GGCGCGCACGGCGGCTATCACGCGATCACGACCTGGCTGCCGACCTACCTGAAGACCGAGCGCCATCTGTCTGTGCTCGG
CACGGGCGCGTATCTCGCCGTGATCATCGTCGCATTCATCGTCGGATGCATGACGAGCGCGTACCTGCAGGACCGCATCG
GCCGCCGCCGGAACCTGATGCTGTTCGCCGCGTGCTGCGTCGTGACGGTCAACCTGTACGTGCTGCTGCCGCTCAACAAC
GTCGCGATGCTGCTGCTCGGCTTCCCGCTCGGCTTCTTCGCGGCCGGGATTCCGGCCACGCTCGGCGCGCTCTTCAACGA
ACTCTATCCGAGGAACGTGCGCGGCCGAGGCGTCGGCTTTTGCTACAACTTCGGCCGCGTCGCCTCGGCGATCTTCCCGG
TGCTCGTCGGGCACATGGGCACGTCGATGCCGCTCGGCGTCGCGCTCGGCATCGACGCGGGCATCGCGTACGGGATCGTG
TTCGTCGCCGTGTGGTTCCTGCCCGAAACGCGCGCGCGCGACTTCCAGGCGTCGCAACCCGATGTCGAGGTCCGCGAAGC
GGCGCTGTAG

Upstream 100 bases:

>100_bases
GTTTCGTGATGCATATGTCGTTTACCCCTCGATAAAATATGACGATATGATGCGGGCTTTTTCTCAACCGCTTATTGCGA
CATCATTCTGGAGAGCACGA

Downstream 100 bases:

>100_bases
ACGCCGCGCGGCCGATCGGGCGCTCGTCATTTGGTGGATTTCTCATGGATCAGGCATCGAACGATCCGGCAGTCGAAACG
ACGGGCCGCACCTTCGCCAC

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSWYKEISPVERRTFKGCFSGWALDGVDTQMFSLVIPALLTSWGIGKGQAGLIGGATLAAGAIGGLLAGMIADRFGRVRA
LQITVCWFSLFTFLSAFAQNFEQLLVLKTLQGIGFGGEWTAGAVLLSETVRAQHRGKAMGIVQSAWGFGWGGAVLLYTLV
FSWLPPEWAWRALFAIGVLPALLVLYIRRAIPEPPRDDARAATSASSTSAMSAASARSSAKGIFDPSVLRMTIVGGLIGV
GAHGGYHAITTWLPTYLKTERHLSVLGTGAYLAVIIVAFIVGCMTSAYLQDRIGRRRNLMLFAACCVVTVNLYVLLPLNN
VAMLLLGFPLGFFAAGIPATLGALFNELYPRNVRGRGVGFCYNFGRVASAIFPVLVGHMGTSMPLGVALGIDAGIAYGIV
FVAVWFLPETRARDFQASQPDVEVREAAL

Sequences:

>Translated_429_residues
MSWYKEISPVERRTFKGCFSGWALDGVDTQMFSLVIPALLTSWGIGKGQAGLIGGATLAAGAIGGLLAGMIADRFGRVRA
LQITVCWFSLFTFLSAFAQNFEQLLVLKTLQGIGFGGEWTAGAVLLSETVRAQHRGKAMGIVQSAWGFGWGGAVLLYTLV
FSWLPPEWAWRALFAIGVLPALLVLYIRRAIPEPPRDDARAATSASSTSAMSAASARSSAKGIFDPSVLRMTIVGGLIGV
GAHGGYHAITTWLPTYLKTERHLSVLGTGAYLAVIIVAFIVGCMTSAYLQDRIGRRRNLMLFAACCVVTVNLYVLLPLNN
VAMLLLGFPLGFFAAGIPATLGALFNELYPRNVRGRGVGFCYNFGRVASAIFPVLVGHMGTSMPLGVALGIDAGIAYGIV
FVAVWFLPETRARDFQASQPDVEVREAAL
>Mature_428_residues
SWYKEISPVERRTFKGCFSGWALDGVDTQMFSLVIPALLTSWGIGKGQAGLIGGATLAAGAIGGLLAGMIADRFGRVRAL
QITVCWFSLFTFLSAFAQNFEQLLVLKTLQGIGFGGEWTAGAVLLSETVRAQHRGKAMGIVQSAWGFGWGGAVLLYTLVF
SWLPPEWAWRALFAIGVLPALLVLYIRRAIPEPPRDDARAATSASSTSAMSAASARSSAKGIFDPSVLRMTIVGGLIGVG
AHGGYHAITTWLPTYLKTERHLSVLGTGAYLAVIIVAFIVGCMTSAYLQDRIGRRRNLMLFAACCVVTVNLYVLLPLNNV
AMLLLGFPLGFFAAGIPATLGALFNELYPRNVRGRGVGFCYNFGRVASAIFPVLVGHMGTSMPLGVALGIDAGIAYGIVF
VAVWFLPETRARDFQASQPDVEVREAAL

Specific function: Probable uptake of 4-methylmuconolactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=447, Percent_Identity=23.7136465324385, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI213021148, Length=444, Percent_Identity=22.0720720720721, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI4506999, Length=434, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87082404, Length=395, Percent_Identity=24.8101265822785, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI87082231, Length=205, Percent_Identity=30.7317073170732, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1786229, Length=441, Percent_Identity=23.8095238095238, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790550, Length=336, Percent_Identity=26.1904761904762, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87082159, Length=336, Percent_Identity=26.1904761904762, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081723, Length=402, Percent_Identity=27.363184079602, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788942, Length=328, Percent_Identity=27.4390243902439, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789152, Length=347, Percent_Identity=22.7665706051873, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789515, Length=349, Percent_Identity=23.4957020057307, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI32564663, Length=438, Percent_Identity=23.0593607305936, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19922616, Length=421, Percent_Identity=24.9406175771971, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19922874, Length=383, Percent_Identity=20.6266318537859, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45867; Mature: 45736

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWYKEISPVERRTFKGCFSGWALDGVDTQMFSLVIPALLTSWGIGKGQAGLIGGATLAA
CCCHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
GAIGGLLAGMIADRFGRVRALQITVCWFSLFTFLSAFAQNFEQLLVLKTLQGIGFGGEWT
HHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
AGAVLLSETVRAQHRGKAMGIVQSAWGFGWGGAVLLYTLVFSWLPPEWAWRALFAIGVLP
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ALLVLYIRRAIPEPPRDDARAATSASSTSAMSAASARSSAKGIFDPSVLRMTIVGGLIGV
HHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
GAHGGYHAITTWLPTYLKTERHLSVLGTGAYLAVIIVAFIVGCMTSAYLQDRIGRRRNLM
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LFAACCVVTVNLYVLLPLNNVAMLLLGFPLGFFAAGIPATLGALFNELYPRNVRGRGVGF
HHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
CYNFGRVASAIFPVLVGHMGTSMPLGVALGIDAGIAYGIVFVAVWFLPETRARDFQASQP
EECHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCHHCCCCCCCCC
DVEVREAAL
CCHHHHCCC
>Mature Secondary Structure 
SWYKEISPVERRTFKGCFSGWALDGVDTQMFSLVIPALLTSWGIGKGQAGLIGGATLAA
CCHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH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CCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9461415 [H]