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The map label for this gene is yhdG [H]

Identifier: 83719187

GI number: 83719187

Start: 241416

End: 242819

Strand: Reverse

Name: yhdG [H]

Synonym: BTH_I0208

Alternate gene names: 83719187

Gene position: 242819-241416 (Counterclockwise)

Preceding gene: 83721309

Following gene: 83720167

Centisome position: 6.37

GC content: 67.59

Gene sequence:

>1404_bases
ATGTCTCTTTTCCGCAAGAAAAACGTCGACCGCATGATCGCCGGCGCGCACGCGGCCGGCCTCAAGAAGGCGCTCGGCGC
GGTCGACCTCACCTTTCTCGGCATCGGCGCGATCATCGGCACCGGCATCTTCGTGCTGACCGGCACGGGCGCCGTGCAAG
CCGGCCCCGCCTTGATGCTGTCGTTCGTGATCGCGGCGATCGCATGCGGCCTCGCCGCGCTGTCGTACGCCGAATTCGCG
TCGACGATCCCCGTCGCCGGCTCGATCTACACGTATTCGTACGCGACCCTCGGCGAGCTCGTCGCGTGGATCATCGGCTG
GGACCTGATGCTCGAGTACGGGCTCGCGGCGTCCGCGGTGTCGGTCGGCTGGTCCGGCTACCTGCAATCGCTGCTGCAGG
GCTTCGGCGTGTCGCTGCCGGCCGCGCTCACCGCCGCGCCGGGCGCGCTGCCGGGCGTCGTCACCTATTTCAACCTGCCG
GCGTTTCTCGTGATGCTCGTCATCACGACGCTGCTGTCGATCGGCATCCGCGAATCGACGCGCGTGAACAACATCATGGT
GTTCATCAAGGTCGCCGTCGTGCTGCTCGTGATCGCGGTCGGCATCTTCCACGTGACGCCCGCGAACTGGAAGCCGTTCA
TGCCGCATGGCTGGAACGGCGTGTTCGGCGCGGCGGCCGTGATGTTCTTCGCGTTCATCGGCTTCGACGCGGTGTCGTCG
GCCGCCGAGGAAGTGAAGAATCCGAAGCGCGATCTGCCGGTCGGCATCATCGCGTCGCTCGGCGTGTGCGCGTTCCTGTA
CGTCGCGGTCGCGGCCATCGCGACGGGCATCGTGCCGTGGGCGCAGTACGCGAACGTCTCGCACCCGATCTCGTACGCGC
TGCAGGTCGCGGGCGAGAAGTGGGTGGCGGGCTTCATCGATCTCGGCGCCGTCATCGGCATGCTGACCGTGATCCTCGTG
ATGAGCTACGGCCAGACCCGGATCATCTTCGCGATGTCGCGCGACGGCCTGCTGCCCGCCGCGCTGTCGCGCGTGCACCC
GCGCTTCGCGACGCCGTTCCTGACGACCTGGCTCGTCGGCCTGTTCTTCGGCCTGATCGCCGCGCTGATTCCGCTGAACG
TGCTCGCCGAGCTGATCAACATCGGCACGCTCGCCGCGTTCTCGATGGTGTCGATCGCGGTGCTCGTGCTGCGCCGCACG
CACCCGGACCTGCCGCGCGCGTTCCGCTGCCCGGGCGTGCCGTTCGTGCCGATCCTCGCGGTCGCCGCGTGCCTGTTCCT
GATGCTGAACCTGCAGCCCGTCACGTGGATCGCGTTCCTGACGTGGCTCGTGATCGGCCTCTTCGTGTACTTCGCCTACT
CGCGCAGCCGCTCGAAGCTTGCGCACGGCGCGCAGCAGCATTGA

Upstream 100 bases:

>100_bases
TCGCGCATCGTCCGGCGCGGGCAAGCGCGTCTTATCCGCTAAAATGCCGGGTTTTCCACTTGTCCGGCGCGCGCCCCGCG
CCGTCCGGTAATCCCTCGCA

Downstream 100 bases:

>100_bases
CGCGCCGTTTCACTCGATGCGCGCCGCGAGCCGGCCGCATCGCTCGCGAACGCGCGTTTCGCTCGAGACGCAACGCTCCC
GGCTTCCGGGAGCGTTTTTT

Product: amino acid permease

Products: L-tryptophan [Cytoplasm]; Proton [Cytoplasm]; Proton [Cytoplasm]; L-tyrosine [Cytoplasm]; Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MSLFRKKNVDRMIAGAHAAGLKKALGAVDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFA
STIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLAASAVSVGWSGYLQSLLQGFGVSLPAALTAAPGALPGVVTYFNLP
AFLVMLVITTLLSIGIRESTRVNNIMVFIKVAVVLLVIAVGIFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSS
AAEEVKNPKRDLPVGIIASLGVCAFLYVAVAAIATGIVPWAQYANVSHPISYALQVAGEKWVAGFIDLGAVIGMLTVILV
MSYGQTRIIFAMSRDGLLPAALSRVHPRFATPFLTTWLVGLFFGLIAALIPLNVLAELINIGTLAAFSMVSIAVLVLRRT
HPDLPRAFRCPGVPFVPILAVAACLFLMLNLQPVTWIAFLTWLVIGLFVYFAYSRSRSKLAHGAQQH

Sequences:

>Translated_467_residues
MSLFRKKNVDRMIAGAHAAGLKKALGAVDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFA
STIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLAASAVSVGWSGYLQSLLQGFGVSLPAALTAAPGALPGVVTYFNLP
AFLVMLVITTLLSIGIRESTRVNNIMVFIKVAVVLLVIAVGIFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSS
AAEEVKNPKRDLPVGIIASLGVCAFLYVAVAAIATGIVPWAQYANVSHPISYALQVAGEKWVAGFIDLGAVIGMLTVILV
MSYGQTRIIFAMSRDGLLPAALSRVHPRFATPFLTTWLVGLFFGLIAALIPLNVLAELINIGTLAAFSMVSIAVLVLRRT
HPDLPRAFRCPGVPFVPILAVAACLFLMLNLQPVTWIAFLTWLVIGLFVYFAYSRSRSKLAHGAQQH
>Mature_466_residues
SLFRKKNVDRMIAGAHAAGLKKALGAVDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFAS
TIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLAASAVSVGWSGYLQSLLQGFGVSLPAALTAAPGALPGVVTYFNLPA
FLVMLVITTLLSIGIRESTRVNNIMVFIKVAVVLLVIAVGIFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSSA
AEEVKNPKRDLPVGIIASLGVCAFLYVAVAAIATGIVPWAQYANVSHPISYALQVAGEKWVAGFIDLGAVIGMLTVILVM
SYGQTRIIFAMSRDGLLPAALSRVHPRFATPFLTTWLVGLFFGLIAALIPLNVLAELINIGTLAAFSMVSIAVLVLRRTH
PDLPRAFRCPGVPFVPILAVAACLFLMLNLQPVTWIAFLTWLVIGLFVYFAYSRSRSKLAHGAQQH

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of The Aromatic Amino Acids (Phenylalanine, Tyrosine, And Tryptophan). [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI181337167, Length=410, Percent_Identity=35.8536585365854, Blast_Score=218, Evalue=6e-57,
Organism=Homo sapiens, GI4507047, Length=436, Percent_Identity=35.7798165137615, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI258645169, Length=426, Percent_Identity=34.5070422535211, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI258614005, Length=426, Percent_Identity=33.5680751173709, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI258614003, Length=426, Percent_Identity=33.5680751173709, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI110347453, Length=385, Percent_Identity=35.8441558441558, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI114326544, Length=433, Percent_Identity=32.7944572748268, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI114326550, Length=433, Percent_Identity=32.7944572748268, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI186910308, Length=432, Percent_Identity=25.9259259259259, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI186910306, Length=432, Percent_Identity=25.9259259259259, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI186910304, Length=432, Percent_Identity=25.9259259259259, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI33286428, Length=476, Percent_Identity=26.890756302521, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI187423910, Length=492, Percent_Identity=25.4065040650407, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI7657591, Length=492, Percent_Identity=25.4065040650407, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI115648063, Length=439, Percent_Identity=24.373576309795, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI115648022, Length=439, Percent_Identity=24.373576309795, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI7657683, Length=405, Percent_Identity=24.6913580246914, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI71979932, Length=419, Percent_Identity=25.7756563245823, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI9790235, Length=299, Percent_Identity=23.0769230769231, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1786302, Length=476, Percent_Identity=23.5294117647059, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082023, Length=450, Percent_Identity=25.5555555555556, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87081915, Length=429, Percent_Identity=23.5431235431235, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1786789, Length=478, Percent_Identity=22.8033472803347, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788480, Length=452, Percent_Identity=26.7699115044248, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786602, Length=476, Percent_Identity=23.5294117647059, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI87081869, Length=461, Percent_Identity=22.9934924078091, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081708, Length=488, Percent_Identity=21.9262295081967, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082250, Length=421, Percent_Identity=23.7529691211401, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789017, Length=445, Percent_Identity=22.6966292134831, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786694, Length=251, Percent_Identity=25.4980079681275, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI48994972, Length=343, Percent_Identity=23.3236151603499, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1790653, Length=420, Percent_Identity=21.4285714285714, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=412, Percent_Identity=36.6504854368932, Blast_Score=245, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17531343, Length=408, Percent_Identity=36.2745098039216, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17533459, Length=411, Percent_Identity=34.0632603406326, Blast_Score=211, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17540018, Length=439, Percent_Identity=25.5125284738041, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17568033, Length=426, Percent_Identity=23.4741784037559, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193208714, Length=414, Percent_Identity=27.536231884058, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32566695, Length=414, Percent_Identity=27.536231884058, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17537453, Length=328, Percent_Identity=27.4390243902439, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI32566699, Length=373, Percent_Identity=25.4691689008043, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71982612, Length=397, Percent_Identity=21.6624685138539, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71982608, Length=397, Percent_Identity=21.6624685138539, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI221512776, Length=415, Percent_Identity=37.8313253012048, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24666159, Length=415, Percent_Identity=37.8313253012048, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24667468, Length=403, Percent_Identity=36.2282878411911, Blast_Score=245, Evalue=5e-65,
Organism=Drosophila melanogaster, GI24668806, Length=429, Percent_Identity=34.032634032634, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI21356285, Length=429, Percent_Identity=34.032634032634, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI24668802, Length=429, Percent_Identity=34.032634032634, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI281366235, Length=427, Percent_Identity=33.9578454332553, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI116007820, Length=427, Percent_Identity=33.9578454332553, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI161077963, Length=424, Percent_Identity=34.9056603773585, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI116007818, Length=413, Percent_Identity=34.1404358353511, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI85725152, Length=413, Percent_Identity=34.1404358353511, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI21357367, Length=424, Percent_Identity=27.3584905660377, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24651635, Length=429, Percent_Identity=25.4079254079254, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24651633, Length=429, Percent_Identity=25.4079254079254, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221331183, Length=448, Percent_Identity=24.3303571428571, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17647653, Length=448, Percent_Identity=24.3303571428571, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24664379, Length=448, Percent_Identity=24.3303571428571, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641995, Length=410, Percent_Identity=25.8536585365854, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24641993, Length=410, Percent_Identity=25.8536585365854, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI45550968, Length=479, Percent_Identity=23.5908141962422, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI19921172, Length=479, Percent_Identity=23.5908141962422, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49464; Mature: 49332

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SLFRKKNVDRMIAGAHAAGLKKALGAVDLTFLGIGAIIGTGIFVLTGTGAVQAGPALML
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHCCHHHHH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HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-tryptophan [Periplasm]; Proton [Periplasm]; Proton [Periplasm]; L-tyrosine [Periplasm]; Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: L-tryptophan [Periplasm] + Proton [Periplasm] = L-tryptophan [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + L-tyrosine [Periplasm] = Proton [Cytoplasm] + L-tyrosine [Cytoplasm] Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] +

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]