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The map label for this gene is marR [H]

Identifier: 83718884

GI number: 83718884

Start: 22608

End: 23153

Strand: Direct

Name: marR [H]

Synonym: BTH_I0021

Alternate gene names: 83718884

Gene position: 22608-23153 (Clockwise)

Preceding gene: 83718594

Following gene: 83721667

Centisome position: 0.59

GC content: 69.41

Gene sequence:

>546_bases
ATGCACTGTTGCGGTTCGCGCAATCGACCGGACAGCTTGACGATGAGCGGCCTATACGACCCGGAGCACATCGAGCTCGA
ATCGAGCCTCGGCTATTACCTGACGAAGGCGCGGCAAGCGCTCGTCGAGCGGCTCGACCGTGCGCTCGGCCCGCTCGAGC
TGACCGCGCAGCAAATCAGCGTGATCCTGTTGCTCGCGCGCGGGTATGCGCGCACGCCGTTCGAGCTGTCGCGCAAGCTG
TCGTACGACAGCGGATCGATGACGCGCATGCTCGACCGGCTCGAGAAGAAGGGCTTCGTCGCGCGCGCGCGCAGCGAATT
GGACCGCCGCGTGATCGAGCTCGCGCTGACCGAGCGCGGCGCGCAGGCCGCGCAGGCGCTGCCCGCGCTGATCGCGACCG
AGCTGAATGCGCAGCTCGAGGGCTTCTCGGCCGGCGAACTCGCGCTCCTGACCGACCTGCTGCGGCGCTTCATCGCGAAC
GCGCCGGGCGCCGCGGATTCCGCATGCGCCGCGTCGATCGCCGAGCCGCCGCCGGGTAAGCGCTGA

Upstream 100 bases:

>100_bases
GAACATTGTCTCTGGCGGCGCATTAAGCGCATAACTCATTGACTGAAATAATATTGACTATGCAATAAATATTCAAGATA
CTGGCGGCGTTTTTCCTGGA

Downstream 100 bases:

>100_bases
CCGGGAAAGAGCATGGACGACCCTCGGATTGCGGCCCGTTTGCCGCCTATTTATCTGTCTGGGCAGAAGCTGACAAGACA
CTTACTGTCGGTCGATGTGG

Product: MarR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MHCCGSRNRPDSLTMSGLYDPEHIELESSLGYYLTKARQALVERLDRALGPLELTAQQISVILLLARGYARTPFELSRKL
SYDSGSMTRMLDRLEKKGFVARARSELDRRVIELALTERGAQAAQALPALIATELNAQLEGFSAGELALLTDLLRRFIAN
APGAADSACAASIAEPPPGKR

Sequences:

>Translated_181_residues
MHCCGSRNRPDSLTMSGLYDPEHIELESSLGYYLTKARQALVERLDRALGPLELTAQQISVILLLARGYARTPFELSRKL
SYDSGSMTRMLDRLEKKGFVARARSELDRRVIELALTERGAQAAQALPALIATELNAQLEGFSAGELALLTDLLRRFIAN
APGAADSACAASIAEPPPGKR
>Mature_181_residues
MHCCGSRNRPDSLTMSGLYDPEHIELESSLGYYLTKARQALVERLDRALGPLELTAQQISVILLLARGYARTPFELSRKL
SYDSGSMTRMLDRLEKKGFVARARSELDRRVIELALTERGAQAAQALPALIATELNAQLEGFSAGELALLTDLLRRFIAN
APGAADSACAASIAEPPPGKR

Specific function: Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081927, Length=130, Percent_Identity=34.6153846153846, Blast_Score=70, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 19728; Mature: 19728

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCCGSRNRPDSLTMSGLYDPEHIELESSLGYYLTKARQALVERLDRALGPLELTAQQIS
CCCCCCCCCCCCCEECCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VILLLARGYARTPFELSRKLSYDSGSMTRMLDRLEKKGFVARARSELDRRVIELALTERG
HHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
AQAAQALPALIATELNAQLEGFSAGELALLTDLLRRFIANAPGAADSACAASIAEPPPGK
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCC
R
C
>Mature Secondary Structure
MHCCGSRNRPDSLTMSGLYDPEHIELESSLGYYLTKARQALVERLDRALGPLELTAQQIS
CCCCCCCCCCCCCEECCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VILLLARGYARTPFELSRKLSYDSGSMTRMLDRLEKKGFVARARSELDRRVIELALTERG
HHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
AQAAQALPALIATELNAQLEGFSAGELALLTDLLRRFIANAPGAADSACAASIAEPPPGK
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 8282690; 7768850; 10760140 [H]