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The map label for this gene is mmgC [H]

Identifier: 83718837

GI number: 83718837

Start: 1563038

End: 1564225

Strand: Reverse

Name: mmgC [H]

Synonym: BTH_I1390

Alternate gene names: 83718837

Gene position: 1564225-1563038 (Counterclockwise)

Preceding gene: 83721237

Following gene: 83720908

Centisome position: 41.06

GC content: 66.75

Gene sequence:

>1188_bases
ATGGCTGCCGCAACCTTCCATTGGGACGATCCGCTGCTGCTCGACCTGCAGCTCAGCGACGACGAGCGCATCGTGCGCGA
CGCCGCGAACGCTTACGCGCAGGGCAAGCTCGCGCCGCGCGTGACGGAAGCGTTCCGCCACGAGACCACGGATGCGGCGA
TCTTCCGCGAAATGGGCGAGGTCGGCCTCCTCGGCCCGACGATTCCCGAGGCGTACGGCGGCCCCGGCTTGAGCTACGTG
AGCTATGGGCTCATCGCGCGCGAGGTCGAGCGCGTCGATTCGGGATACCGGTCGATGATGTCGGTGCAGTCGTCGCTCGT
GATGGTGCCGATCTTCGAATTCGGCTCCGACGCGCAGAAGGAAAAGTACCTGCCGAAGCTCGCGACGGGCGAGTGGATCG
GCTGCTTCGGCCTGACCGAGCCGAACCACGGCTCCGATCCGGGCAGCATGGTCACGCGCGCGAAGAAGGTGCCGGGCGGC
TACGCGCTGTCGGGCTCGAAGATGTGGATCACGAATTCGCCGATCGCCGACGTGTTCGTCGTCTGGGCGAAGCTCGACGA
GGACGGGCGCGACGAGATTCGCGGCTTCATCCTCGAGAAGGGCTGGAAGGGCCTGTCGGCGCCGGCGATCCACGGCAAGG
TGGGCCTGCGCGCGTCGATCACGGGCGAGATCGTGCTCGACGAAGTGTTCGTCCCCGAAGAGAACATCCTGCCGAACGTA
AAGGGCCTGCGCGGGCCGTTCACGTGCCTGAACTCGGCGCGCTACGGGATCGCGTGGGGCGCGCTCGGCGCGGCGGAGTC
GTGCTGGCACACGGCGCGCCAGTACGTGCTCGATCGCAAGCAGTTCGGCCGTCCGCTCGCCGCGAACCAGTTGATCCAGA
AGAAGCTCGCGGACATGCAGACCGAGATCACGCTCGGCCTGCAGGGCGTGCTGCGGCTCGGCCGGATGAAGGACGAATGC
ACCGCCGCCGTCGAGATCACGTCGATCATGAAGCGCAATTCGTGCGGCAAGGCGCTCGACATCGCCCGCCTCGCCCGCGA
CATGCTGGGCGGCAACGGCATCTCGGACGAATTCGGCGTCGCGCGCCACCTCGTGAACCTCGAAGTGGTGAACACGTACG
AAGGCACGCACGACATCCACGCGCTGATCCTCGGCCGCGCGCAAACGGGAATTCAGGCGTTCTTCTGA

Upstream 100 bases:

>100_bases
GGCATCGATGGTCGAAAAATTCATGCGGTGATACACTGGGGCCAATTTGCAAAACATTGTTCCGCATAGCGGAACTACAG
TCAAGCGAGGAGATGACGAG

Downstream 100 bases:

>100_bases
GTTTTGCGAACGTCGCGCGGATGCGGCACCGGCGTTCTCTTCGCCAACGCGCCGAGCCAGAGCCGGCGCGGCCGCGCGGA
CGACGCGCGGCACCCGTGCG

Product: glutaryl-CoA dehydrogenase

Products: crotonoyl-CoA; CO2; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MAAATFHWDDPLLLDLQLSDDERIVRDAANAYAQGKLAPRVTEAFRHETTDAAIFREMGEVGLLGPTIPEAYGGPGLSYV
SYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEFGSDAQKEKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVPGG
YALSGSKMWITNSPIADVFVVWAKLDEDGRDEIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENILPNV
KGLRGPFTCLNSARYGIAWGALGAAESCWHTARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEC
TAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF

Sequences:

>Translated_395_residues
MAAATFHWDDPLLLDLQLSDDERIVRDAANAYAQGKLAPRVTEAFRHETTDAAIFREMGEVGLLGPTIPEAYGGPGLSYV
SYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEFGSDAQKEKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVPGG
YALSGSKMWITNSPIADVFVVWAKLDEDGRDEIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENILPNV
KGLRGPFTCLNSARYGIAWGALGAAESCWHTARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEC
TAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF
>Mature_394_residues
AAATFHWDDPLLLDLQLSDDERIVRDAANAYAQGKLAPRVTEAFRHETTDAAIFREMGEVGLLGPTIPEAYGGPGLSYVS
YGLIAREVERVDSGYRSMMSVQSSLVMVPIFEFGSDAQKEKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVPGGY
ALSGSKMWITNSPIADVFVVWAKLDEDGRDEIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENILPNVK
GLRGPFTCLNSARYGIAWGALGAAESCWHTARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDECT
AAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=391, Percent_Identity=66.7519181585678, Blast_Score=520, Evalue=1e-148,
Organism=Homo sapiens, GI7669494, Length=371, Percent_Identity=65.2291105121294, Blast_Score=483, Evalue=1e-136,
Organism=Homo sapiens, GI226958412, Length=378, Percent_Identity=35.1851851851852, Blast_Score=204, Evalue=8e-53,
Organism=Homo sapiens, GI226958414, Length=346, Percent_Identity=35.2601156069364, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI4557233, Length=374, Percent_Identity=31.283422459893, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI4501859, Length=365, Percent_Identity=29.5890410958904, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI4557235, Length=347, Percent_Identity=33.1412103746398, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI76496475, Length=347, Percent_Identity=33.1412103746398, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI21361497, Length=348, Percent_Identity=32.7586206896552, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI4557231, Length=397, Percent_Identity=29.2191435768262, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI187960098, Length=397, Percent_Identity=29.2191435768262, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI7656849, Length=380, Percent_Identity=28.9473684210526, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI4501857, Length=379, Percent_Identity=29.287598944591, Blast_Score=133, Evalue=2e-31,
Organism=Escherichia coli, GI1786223, Length=380, Percent_Identity=24.7368421052632, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081958, Length=349, Percent_Identity=26.9340974212034, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17534353, Length=394, Percent_Identity=62.9441624365482, Blast_Score=504, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI17508101, Length=376, Percent_Identity=33.5106382978723, Blast_Score=187, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17538396, Length=374, Percent_Identity=32.3529411764706, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=30.4109589041096, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI71990804, Length=260, Percent_Identity=38.0769230769231, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=29.5514511873351, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71985184, Length=356, Percent_Identity=32.0224719101124, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17534899, Length=379, Percent_Identity=29.287598944591, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71985192, Length=266, Percent_Identity=34.2105263157895, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71982178, Length=279, Percent_Identity=32.9749103942652, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17570075, Length=379, Percent_Identity=27.9683377308707, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=34.6320346320346, Blast_Score=138, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17533517, Length=373, Percent_Identity=26.0053619302949, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17505929, Length=353, Percent_Identity=26.0623229461756, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17551932, Length=359, Percent_Identity=25.3481894150418, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17531909, Length=233, Percent_Identity=29.1845493562232, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19920834, Length=397, Percent_Identity=62.4685138539043, Blast_Score=489, Evalue=1e-138,
Organism=Drosophila melanogaster, GI21356377, Length=370, Percent_Identity=31.8918918918919, Blast_Score=201, Evalue=9e-52,
Organism=Drosophila melanogaster, GI24666513, Length=365, Percent_Identity=32.3287671232877, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=32.258064516129, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI21355753, Length=375, Percent_Identity=32.2666666666667, Blast_Score=174, Evalue=7e-44,
Organism=Drosophila melanogaster, GI281363737, Length=378, Percent_Identity=31.4814814814815, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=29.8941798941799, Blast_Score=155, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.7

Molecular weight: Translated: 43057; Mature: 42926

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAATFHWDDPLLLDLQLSDDERIVRDAANAYAQGKLAPRVTEAFRHETTDAAIFREMGE
CCCCEEECCCCEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCC
VGLLGPTIPEAYGGPGLSYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEFGSDAQK
CCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHCCCCCHH
EKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVPGGYALSGSKMWITNSPIADVFV
HHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEECCCEEEEECCCHHHHEE
VWAKLDEDGRDEIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENILPNV
EEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCC
KGLRGPFTCLNSARYGIAWGALGAAESCWHTARQYVLDRKQFGRPLAANQLIQKKLADMQ
CCCCCHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TEITLGLQGVLRLGRMKDECTAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHH
ARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF
HHHHHEEEEEECCCCCHHEEHHEEECHHCCHHHCC
>Mature Secondary Structure 
AAATFHWDDPLLLDLQLSDDERIVRDAANAYAQGKLAPRVTEAFRHETTDAAIFREMGE
CCCEEECCCCEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCC
VGLLGPTIPEAYGGPGLSYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEFGSDAQK
CCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHCCCCCHH
EKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVPGGYALSGSKMWITNSPIADVFV
HHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEECCCEEEEECCCHHHHEE
VWAKLDEDGRDEIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENILPNV
EEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCC
KGLRGPFTCLNSARYGIAWGALGAAESCWHTARQYVLDRKQFGRPLAANQLIQKKLADMQ
CCCCCHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TEITLGLQGVLRLGRMKDECTAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHH
ARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF
HHHHHEEEEEECCCCCHHEEHHEEECHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutaryl-CoA; acceptor

Specific reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]