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The map label for this gene is clpP [H]

Identifier: 83718816

GI number: 83718816

Start: 2392814

End: 2393437

Strand: Direct

Name: clpP [H]

Synonym: BTH_I2120

Alternate gene names: 83718816

Gene position: 2392814-2393437 (Clockwise)

Preceding gene: 83719759

Following gene: 83721081

Centisome position: 62.82

GC content: 64.1

Gene sequence:

>624_bases
TTGGCTTCGCAAGCCCCGCGGGATTTCGAGGCGCAAGCGCTCGGGCTCGTGCCGATCGTCGTCGAGACGAGCGGCCGCGG
CGAGCGTTCGTACGACATCTACTCGCGGCTTCTGAAAGAGCGCATCGTGTTCATGGTCGGCGAGGTCAACGATCAGACGG
CGAATCTCGTGGTCGCGCAGTTGCTGTTCCTCGAAAGCGAGAATCCCGACAAGGACATCAGCCTGTACATCAACAGCCCG
GGCGGCTCGGTGTCGGCGGGGATGGCGATTTACGACACGATGCAGTTCGTGAAGCCGGACGTGTCGACGCTCTGCATGGG
CCTTGCGGCCAGCATGGGGGCGTTCCTGCTCGCGTCGGGCGCAAAGGGCAAGCGCTATGCGCTGCCGAACGCGCGCGTGA
TGATCCACCAGCCGCTCGGCGGCGCGCGCGGCCAGGCGTCGGATATCGAGATCCAGGCGCGCGAGATCCTCTACCTGAAG
GATCGCCTGAACCACCTGCTCGCCCACCATACCGGTCAGGACGTCGAGCGCATCGCGCGCGACACCGACCGTGATAATTT
CATGTCCAGCGAAGATGCGAAGGCGTACGGGCTGATCGACCACGTGTCGACGAAGCGTCCGTAA

Upstream 100 bases:

>100_bases
CGCCGCGCGTGCGGCGTTCTCCGGCTCGTTTCCTGCCGTTCAATACTCATTCTCGGACAAGGCTCATTGAATGATTAATC
GCGCTCAATTGCTGGACACG

Downstream 100 bases:

>100_bases
GCTTTAGTGGGGTGCCGCCCCAATAGGGGCGGCGCCCGCCGAGCGCCCCGAGCATCTGCGGCAAAAGAACATCGCCGCCG
TCTCCCGAGTATTTACCAGG

Product: ATP-dependent Clp protease proteolytic subunit

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MASQAPRDFEAQALGLVPIVVETSGRGERSYDIYSRLLKERIVFMVGEVNDQTANLVVAQLLFLESENPDKDISLYINSP
GGSVSAGMAIYDTMQFVKPDVSTLCMGLAASMGAFLLASGAKGKRYALPNARVMIHQPLGGARGQASDIEIQAREILYLK
DRLNHLLAHHTGQDVERIARDTDRDNFMSSEDAKAYGLIDHVSTKRP

Sequences:

>Translated_207_residues
MASQAPRDFEAQALGLVPIVVETSGRGERSYDIYSRLLKERIVFMVGEVNDQTANLVVAQLLFLESENPDKDISLYINSP
GGSVSAGMAIYDTMQFVKPDVSTLCMGLAASMGAFLLASGAKGKRYALPNARVMIHQPLGGARGQASDIEIQAREILYLK
DRLNHLLAHHTGQDVERIARDTDRDNFMSSEDAKAYGLIDHVSTKRP
>Mature_206_residues
ASQAPRDFEAQALGLVPIVVETSGRGERSYDIYSRLLKERIVFMVGEVNDQTANLVVAQLLFLESENPDKDISLYINSPG
GSVSAGMAIYDTMQFVKPDVSTLCMGLAASMGAFLLASGAKGKRYALPNARVMIHQPLGGARGQASDIEIQAREILYLKD
RLNHLLAHHTGQDVERIARDTDRDNFMSSEDAKAYGLIDHVSTKRP

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=196, Percent_Identity=56.6326530612245, Blast_Score=238, Evalue=3e-63,
Organism=Escherichia coli, GI1786641, Length=206, Percent_Identity=66.0194174757282, Blast_Score=298, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI17538017, Length=188, Percent_Identity=54.2553191489362, Blast_Score=220, Evalue=4e-58,
Organism=Drosophila melanogaster, GI20129427, Length=194, Percent_Identity=57.2164948453608, Blast_Score=243, Evalue=7e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 22669; Mature: 22538

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00381 CLP_PROTEASE_SER ; PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASQAPRDFEAQALGLVPIVVETSGRGERSYDIYSRLLKERIVFMVGEVNDQTANLVVAQ
CCCCCCCCCCCHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHEEEECCCCCHHHHHHHHH
LLFLESENPDKDISLYINSPGGSVSAGMAIYDTMQFVKPDVSTLCMGLAASMGAFLLASG
HHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEECC
AKGKRYALPNARVMIHQPLGGARGQASDIEIQAREILYLKDRLNHLLAHHTGQDVERIAR
CCCCEEECCCCEEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
DTDRDNFMSSEDAKAYGLIDHVSTKRP
CCCCCCCCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
ASQAPRDFEAQALGLVPIVVETSGRGERSYDIYSRLLKERIVFMVGEVNDQTANLVVAQ
CCCCCCCCCCHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHEEEECCCCCHHHHHHHHH
LLFLESENPDKDISLYINSPGGSVSAGMAIYDTMQFVKPDVSTLCMGLAASMGAFLLASG
HHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEECC
AKGKRYALPNARVMIHQPLGGARGQASDIEIQAREILYLKDRLNHLLAHHTGQDVERIAR
CCCCEEECCCCEEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
DTDRDNFMSSEDAKAYGLIDHVSTKRP
CCCCCCCCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA