BacMap

Definition	Burkholderia thailandensis E264 chromosome chromosome I, complete sequence.
Accession	NC_007651
Length	3,809,201

Click here to switch to the map view.

The map label for this gene is hmuV [H]

Identifier: 83718646

GI number: 83718646

Start: 951096

End: 951926

Strand: Direct

Name: hmuV [H]

Synonym: BTH_I0836

Alternate gene names: 83718646

Gene position: 951096-951926 (Clockwise)

Preceding gene: 83718866

Following gene: 83719548

Centisome position: 24.97

GC content: 74.61

Gene sequence:

>831_bases
ATGACGGAGCACGACGCGCCGACGTCGCGCTCGCCCCGCTACGGCACGCAGCGTCTCGTGCTGAAGGCGGGCGCGCGCAC
GCTGCTCGACGACTTCACGCACACGTTCTATCCGGGCGAGCTGTGGTGCGTCGCCGGGCCGAACGGCGCGGGAAAGACGA
CGCTGATCACGACGCTCGCGGGGCTCGCGAGGCCGGCCGCCGGGCACGTCGAGGCGGACGGCGTGCCGCTCGCCGACTGG
CGGCCCGAAGCGCTCGCGAAGCGGCGCGCGTTGATGGCGCAGACGCTGCACGACGCGTTCAGCGCGAGCGTGTTCGATAC
CGTGCTGCTCGCCCGCTTTCCGCATCTGACGGGCTGGGGCTGGGAGCGCGCCGACGACCGCGCGGCCGCGCACGCGGCGC
TCGCGCGGCTCGGGCTCGAATCGTTCGCCGCGCGCGACGTGCTGACGCTGTCGGGCGGCGAGCGGCAACGCGTCGCGCTC
GCGGCCGCGCTGTGCCAGGACGCGCCGCTGCTGTTGCTCGACGAGCCGCTCGCGCACCTCGACCTGCACCATCAGATCGA
CTGTCTCGCCGCGCTCGCCGACTGGCTGCGCGCGGGCGAGCGCACCGCGATCTTCTCGTGCCACGACCTGAATCTCGCGC
GCCGTTTCGCGACGCACGCGCTGTTGCTCGACGGCCGCGGCGGCGCGCACGCGGGCCCGGTGCGCGATGTGCTGACGCCC
GAGCGCGCGAGCCGCGCGTTCGGCTACCCGCTCGTGCTGATCGAGCGCGACGGCCACGAGGCGCTCGTGCCCGCGTGGCC
CGCCGCGCACGATCGTTCCCGCATCACCTGA

Upstream 100 bases:

>100_bases
CGCGCACGGCGATCGCGCCCGCGCAGCTCCCGGTCGGCGTGATGACGGCGTTGATCGGCGTGCCGCTCTTCCTGTGGATG
CTGCTGCGGAGGACCGCGCG

Downstream 100 bases:

>100_bases
TCGACGCGCATCGCGCGCCCCATTTCATCCACGAGACGAACCGATGACCTCCACCTTCTCCCTGCCGAGCATTGAGCCGC
TCGACGACGCCGCGCTGCGC

Product: iron compound ABC transporter ATP-binding protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MTEHDAPTSRSPRYGTQRLVLKAGARTLLDDFTHTFYPGELWCVAGPNGAGKTTLITTLAGLARPAAGHVEADGVPLADW
RPEALAKRRALMAQTLHDAFSASVFDTVLLARFPHLTGWGWERADDRAAAHAALARLGLESFAARDVLTLSGGERQRVAL
AAALCQDAPLLLLDEPLAHLDLHHQIDCLAALADWLRAGERTAIFSCHDLNLARRFATHALLLDGRGGAHAGPVRDVLTP
ERASRAFGYPLVLIERDGHEALVPAWPAAHDRSRIT

Sequences:

>Translated_276_residues
MTEHDAPTSRSPRYGTQRLVLKAGARTLLDDFTHTFYPGELWCVAGPNGAGKTTLITTLAGLARPAAGHVEADGVPLADW
RPEALAKRRALMAQTLHDAFSASVFDTVLLARFPHLTGWGWERADDRAAAHAALARLGLESFAARDVLTLSGGERQRVAL
AAALCQDAPLLLLDEPLAHLDLHHQIDCLAALADWLRAGERTAIFSCHDLNLARRFATHALLLDGRGGAHAGPVRDVLTP
ERASRAFGYPLVLIERDGHEALVPAWPAAHDRSRIT
>Mature_275_residues
TEHDAPTSRSPRYGTQRLVLKAGARTLLDDFTHTFYPGELWCVAGPNGAGKTTLITTLAGLARPAAGHVEADGVPLADWR
PEALAKRRALMAQTLHDAFSASVFDTVLLARFPHLTGWGWERADDRAAAHAALARLGLESFAARDVLTLSGGERQRVALA
AALCQDAPLLLLDEPLAHLDLHHQIDCLAALADWLRAGERTAIFSCHDLNLARRFATHALLLDGRGGAHAGPVRDVLTPE
RASRAFGYPLVLIERDGHEALVPAWPAAHDRSRIT

Specific function: Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system [H]

COG id: COG1120

COG function: function code PH; ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI108773784, Length=197, Percent_Identity=28.4263959390863, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI108773782, Length=197, Percent_Identity=28.4263959390863, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI73747915, Length=211, Percent_Identity=28.9099526066351, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI9665248, Length=209, Percent_Identity=29.6650717703349, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI171184400, Length=203, Percent_Identity=29.064039408867, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI27881501, Length=240, Percent_Identity=27.9166666666667, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI30795238, Length=240, Percent_Identity=27.9166666666667, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI156105685, Length=203, Percent_Identity=31.0344827586207, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1786803, Length=249, Percent_Identity=34.5381526104418, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1790739, Length=226, Percent_Identity=32.7433628318584, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786345, Length=241, Percent_Identity=31.9502074688797, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1788002, Length=232, Percent_Identity=34.051724137931, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87081709, Length=213, Percent_Identity=30.5164319248826, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786253, Length=197, Percent_Identity=33.502538071066, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87081791, Length=206, Percent_Identity=31.0679611650485, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786563, Length=203, Percent_Identity=34.4827586206897, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1786872, Length=182, Percent_Identity=32.4175824175824, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1789873, Length=203, Percent_Identity=32.0197044334975, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788225, Length=221, Percent_Identity=29.4117647058824, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789032, Length=237, Percent_Identity=29.957805907173, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1790544, Length=194, Percent_Identity=31.4432989690722, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87081834, Length=203, Percent_Identity=31.0344827586207, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787029, Length=230, Percent_Identity=27.8260869565217, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786698, Length=204, Percent_Identity=27.9411764705882, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1789891, Length=204, Percent_Identity=31.3725490196078, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788450, Length=202, Percent_Identity=31.1881188118812, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787112, Length=196, Percent_Identity=33.1632653061224, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082267, Length=214, Percent_Identity=26.6355140186916, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787370, Length=247, Percent_Identity=29.5546558704453, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788761, Length=213, Percent_Identity=30.5164319248826, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787143, Length=189, Percent_Identity=28.042328042328, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787712, Length=186, Percent_Identity=30.6451612903226, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1786653, Length=185, Percent_Identity=28.6486486486486, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786703, Length=189, Percent_Identity=34.3915343915344, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789672, Length=215, Percent_Identity=28.3720930232558, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1789962, Length=198, Percent_Identity=25.7575757575758, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786398, Length=205, Percent_Identity=30.2439024390244, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787500, Length=204, Percent_Identity=25.4901960784314, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788210, Length=183, Percent_Identity=29.5081967213115, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787105, Length=190, Percent_Identity=31.0526315789474, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787164, Length=186, Percent_Identity=36.5591397849462, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789751, Length=209, Percent_Identity=31.5789473684211, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790467, Length=209, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787089, Length=213, Percent_Identity=29.1079812206573, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786319, Length=172, Percent_Identity=29.0697674418605, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788644, Length=213, Percent_Identity=26.2910798122066, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789593, Length=225, Percent_Identity=28, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788540, Length=180, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71992290, Length=221, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17511077, Length=196, Percent_Identity=29.5918367346939, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17543740, Length=191, Percent_Identity=28.2722513089005, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17558664, Length=177, Percent_Identity=32.7683615819209, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17565938, Length=192, Percent_Identity=28.6458333333333, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17541710, Length=189, Percent_Identity=31.2169312169312, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17569145, Length=190, Percent_Identity=31.0526315789474, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17567265, Length=204, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533592, Length=190, Percent_Identity=27.3684210526316, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115535101, Length=189, Percent_Identity=29.6296296296296, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=178, Percent_Identity=29.7752808988764, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323959, Length=187, Percent_Identity=24.5989304812834, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322640, Length=198, Percent_Identity=26.7676767676768, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281362751, Length=206, Percent_Identity=28.6407766990291, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24650853, Length=214, Percent_Identity=28.5046728971963, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24650855, Length=214, Percent_Identity=28.5046728971963, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24659289, Length=178, Percent_Identity=31.4606741573034, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI85726357, Length=191, Percent_Identity=30.3664921465969, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648314, Length=158, Percent_Identity=27.8481012658228, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015863
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 29846; Mature: 29715

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEHDAPTSRSPRYGTQRLVLKAGARTLLDDFTHTFYPGELWCVAGPNGAGKTTLITTLA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHH
GLARPAAGHVEADGVPLADWRPEALAKRRALMAQTLHDAFSASVFDTVLLARFPHLTGWG
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
WERADDRAAAHAALARLGLESFAARDVLTLSGGERQRVALAAALCQDAPLLLLDEPLAHL
CCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCCEEEECCCHHHH
DLHHQIDCLAALADWLRAGERTAIFSCHDLNLARRFATHALLLDGRGGAHAGPVRDVLTP
HHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHEEEEECCCCCCCCCHHHHCCH
ERASRAFGYPLVLIERDGHEALVPAWPAAHDRSRIT
HHHHHHCCCEEEEEECCCCCEECCCCCCCCCCCCCC
>Mature Secondary Structure 
TEHDAPTSRSPRYGTQRLVLKAGARTLLDDFTHTFYPGELWCVAGPNGAGKTTLITTLA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHH
GLARPAAGHVEADGVPLADWRPEALAKRRALMAQTLHDAFSASVFDTVLLARFPHLTGWG
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
WERADDRAAAHAALARLGLESFAARDVLTLSGGERQRVALAAALCQDAPLLLLDEPLAHL
CCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCCEEEECCCHHHH
DLHHQIDCLAALADWLRAGERTAIFSCHDLNLARRFATHALLLDGRGGAHAGPVRDVLTP
HHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHEEEEECCCCCCCCCHHHHCCH
ERASRAFGYPLVLIERDGHEALVPAWPAAHDRSRIT
HHHHHHCCCEEEEEECCCCCEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA