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The map label for this gene is livH [H]

Identifier: 83718581

GI number: 83718581

Start: 3025079

End: 3026014

Strand: Reverse

Name: livH [H]

Synonym: BTH_I2653

Alternate gene names: 83718581

Gene position: 3026014-3025079 (Counterclockwise)

Preceding gene: 83721514

Following gene: 83719219

Centisome position: 79.44

GC content: 72.33

Gene sequence:

>936_bases
GTGCAGTCGATCGTCGTCAATCTGCTGAACGGCCTGAGCTACGGGCTGCTGCTGTTCATGCTGTGTGCGGGGCTCACGCT
GATCTTCGGCATGCTCGGGGTGCTCAATTTCGCGCATGCGAGCTTCTACATGCTCGGCGCGTACGCCGGCTGCGCGATCG
CCGCGCGCACGAGCTTCTGGGTCGCGCTCGTCGCCGCGCCGCTCGCCGTCGGCGCATTCGGCGCGCTCTGCGAGCGCACG
CTGCTCAGGCGGGTGCGGTCGGGCGGCCATCTGGACGAGTTGCTGCTCACGTTCGGGCTCGCGTATCTGATCGGCGAAGG
CGTGAAGCTCGTGTGGGGGCTCGCGCCGCTCACCGCGCCCGTGCCCGCCGTGCTCGACGGCGCGGCGTTCACCGTCTACG
GCGCCGTCTTCCCGCGTTATCGCGTGTTCATGACGAGCGTGTCGTTCGCGATGCTCGGCGCGCTGTGGGCGGTGCTGCGC
GTGTCGCAGACCGGGCTCGTCGTGCGCGCGGCGCTCACGCATCGCGCGGCCGTCGAGGCGCTCGGCCACGACGTGCCGCG
CGTGATGACGCTCGTGTTCGCCGCAGGCACCGCGCTTGCCGCGCTCGCCGGCGTGATCGGCGCGCCGCTCGCGGTGATCG
AGCCCGCGATGGCGCAGACGCTCGGCTCGGTCGTGTTCGCGGTGATCGTGATCGGCGGGCTCGGTTCGCTCGCGGGCGCG
CTCGTCGCATCGCTCGCGGTGGGCTGCGCGCAGACGTTCGCGACGGCGAGCCGCGCATCGCTCGGCGACGCGGCGCAGTG
GGCGGGCATCGCGCTGCCCGACGCGTGGCGCGCGTTGACGCTCGCGCAGCTCGCACCGCTGATTCCGTATCTGCTGCTCG
TCGCGGTGCTCGCGTGCCGCGCGCGCGGCCTGTTCGGCGAGCGCGCCGATGTCTAG

Upstream 100 bases:

>100_bases
GTGCACGTGTACGTCGATCGCGCGACGCGCCGGCCGGTGCCGCTGCCCGAGCCGCTGCGCGCCGCGCTCGCGCCGCTCGT
CGCGCAGGCGGCCTGACGCG

Downstream 100 bases:

>100_bases
CGCGAACGCGGCGCGAAGCCGCCTGCCGGAAGCGCTGTCATGGCTTGCGCTCGTCGCGCTGCTCGTCGTGCCCGCGCTCG
CGTGGCCGCGCGGCTGGATG

Product: branched-chain amino acid ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MQSIVVNLLNGLSYGLLLFMLCAGLTLIFGMLGVLNFAHASFYMLGAYAGCAIAARTSFWVALVAAPLAVGAFGALCERT
LLRRVRSGGHLDELLLTFGLAYLIGEGVKLVWGLAPLTAPVPAVLDGAAFTVYGAVFPRYRVFMTSVSFAMLGALWAVLR
VSQTGLVVRAALTHRAAVEALGHDVPRVMTLVFAAGTALAALAGVIGAPLAVIEPAMAQTLGSVVFAVIVIGGLGSLAGA
LVASLAVGCAQTFATASRASLGDAAQWAGIALPDAWRALTLAQLAPLIPYLLLVAVLACRARGLFGERADV

Sequences:

>Translated_311_residues
MQSIVVNLLNGLSYGLLLFMLCAGLTLIFGMLGVLNFAHASFYMLGAYAGCAIAARTSFWVALVAAPLAVGAFGALCERT
LLRRVRSGGHLDELLLTFGLAYLIGEGVKLVWGLAPLTAPVPAVLDGAAFTVYGAVFPRYRVFMTSVSFAMLGALWAVLR
VSQTGLVVRAALTHRAAVEALGHDVPRVMTLVFAAGTALAALAGVIGAPLAVIEPAMAQTLGSVVFAVIVIGGLGSLAGA
LVASLAVGCAQTFATASRASLGDAAQWAGIALPDAWRALTLAQLAPLIPYLLLVAVLACRARGLFGERADV
>Mature_311_residues
MQSIVVNLLNGLSYGLLLFMLCAGLTLIFGMLGVLNFAHASFYMLGAYAGCAIAARTSFWVALVAAPLAVGAFGALCERT
LLRRVRSGGHLDELLLTFGLAYLIGEGVKLVWGLAPLTAPVPAVLDGAAFTVYGAVFPRYRVFMTSVSFAMLGALWAVLR
VSQTGLVVRAALTHRAAVEALGHDVPRVMTLVFAAGTALAALAGVIGAPLAVIEPAMAQTLGSVVFAVIVIGGLGSLAGA
LVASLAVGCAQTFATASRASLGDAAQWAGIALPDAWRALTLAQLAPLIPYLLLVAVLACRARGLFGERADV

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=265, Percent_Identity=26.4150943396226, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 31981; Mature: 31981

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCCCCC
>Mature Secondary Structure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HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]