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The map label for this gene is mlaA [H]

Identifier: 83718408

GI number: 83718408

Start: 3439333

End: 3440268

Strand: Reverse

Name: mlaA [H]

Synonym: BTH_I3001

Alternate gene names: 83718408

Gene position: 3440268-3439333 (Counterclockwise)

Preceding gene: 83719153

Following gene: 83720958

Centisome position: 90.31

GC content: 70.62

Gene sequence:

>936_bases
ATGCAGACGATCCGCATCAGCCAAGCGGTGCTGGCGGTCACGGCCGCCGCGGCATTGAGCGGTTGCGCGACGGTCCAGAC
GCCGACGAAGGGCGATCCGTTCGAAGGCTTCAACCGGACGATGTACACGTTCAACGACAAGGTCGACCAGTACGCGCTCA
AGCCGGTCGCGCGCGGCTACCAGTGGGCGGTGCCGCAGCCGATGCGCGACAGCGTGACGAACTTCTTCTCGAACATCGGC
GACGTCTACATCGCCGCGAACAACCTCGTGCAGTTGAAGATCGCCGACGGCGTCGGCGATATCATGCGGGTCGTGATCAA
CACGGTGTTCGGCGTGGGCGGCCTGTTCGACGTCGCGACGCTCGCGAAGCTGCCGAAGCACGCGAACGACTTCGGCGTGA
CGCTCGGCCACTACGGCGTGCCGAGCGGCCCGTACCTCGTGCTGCCGCTGCTCGGCCCGAGCACCGTGCGCGACACGGCG
GGCCTCGCCGTCGACTACGCGGGCAACCCGCTCACCTACGTGCGGCCCGACAGCGTGAGCTGGGGCCTGTTCGGCCTGAA
CCTCGTGAACACGCGCGCGAACCTGCTGGGCGCGGGCGACGTGCTCGAGGCGGCCGCGATCGACAAGTATTCGTTCGTGC
GCAACGCGTACCTGCAGCGCCGTCAGGCGTTGATCGGCGGTGGCGCGGGGGCGCAGTCGAACCTGCCGGATTACGGCAAC
GAAGCGCCGCCGCCGAATTACGAGATGCCGGAGGAGGGCGCCGCGGCGCCCGCGAGCGGCGCGGCCGCGGCGCCGGCGGC
ATCGGGCGCGCCGGCCGTGGCTGCACCGGCCGCGGCCTCGGCGCCGAACCCGAGCAGCGCGACGAACGTGCCGGCGCAGC
AGGTCGTGCCGCCGTCGCCGGGCGGCATCCATTGGCCGAGCATCCGGCTGCACTGA

Upstream 100 bases:

>100_bases
CCGCCGCGTCGGGCGCGCCCGCGCCGGCCGCGTCGGGCGCGGCGGCACATTGAACGCCGCGCGAGCGGCATACGAGAGAA
GAAGCGAGGGGAAGAACATC

Downstream 100 bases:

>100_bases
TCCGGCGCTTACATCGGTTACAGCCGGAAACGATTCTGACGGCGGCCGGCGAGAACTTGCGCCGCCGTCGATGGTTCCAA
GTCTGGCATCGACTCACACA

Product: lipoprotein VacJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MQTIRISQAVLAVTAAAALSGCATVQTPTKGDPFEGFNRTMYTFNDKVDQYALKPVARGYQWAVPQPMRDSVTNFFSNIG
DVYIAANNLVQLKIADGVGDIMRVVINTVFGVGGLFDVATLAKLPKHANDFGVTLGHYGVPSGPYLVLPLLGPSTVRDTA
GLAVDYAGNPLTYVRPDSVSWGLFGLNLVNTRANLLGAGDVLEAAAIDKYSFVRNAYLQRRQALIGGGAGAQSNLPDYGN
EAPPPNYEMPEEGAAAPASGAAAAPAASGAPAVAAPAAASAPNPSSATNVPAQQVVPPSPGGIHWPSIRLH

Sequences:

>Translated_311_residues
MQTIRISQAVLAVTAAAALSGCATVQTPTKGDPFEGFNRTMYTFNDKVDQYALKPVARGYQWAVPQPMRDSVTNFFSNIG
DVYIAANNLVQLKIADGVGDIMRVVINTVFGVGGLFDVATLAKLPKHANDFGVTLGHYGVPSGPYLVLPLLGPSTVRDTA
GLAVDYAGNPLTYVRPDSVSWGLFGLNLVNTRANLLGAGDVLEAAAIDKYSFVRNAYLQRRQALIGGGAGAQSNLPDYGN
EAPPPNYEMPEEGAAAPASGAAAAPAASGAPAVAAPAAASAPNPSSATNVPAQQVVPPSPGGIHWPSIRLH
>Mature_311_residues
MQTIRISQAVLAVTAAAALSGCATVQTPTKGDPFEGFNRTMYTFNDKVDQYALKPVARGYQWAVPQPMRDSVTNFFSNIG
DVYIAANNLVQLKIADGVGDIMRVVINTVFGVGGLFDVATLAKLPKHANDFGVTLGHYGVPSGPYLVLPLLGPSTVRDTA
GLAVDYAGNPLTYVRPDSVSWGLFGLNLVNTRANLLGAGDVLEAAAIDKYSFVRNAYLQRRQALIGGGAGAQSNLPDYGN
EAPPPNYEMPEEGAAAPASGAAAAPAASGAPAVAAPAAASAPNPSSATNVPAQQVVPPSPGGIHWPSIRLH

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane [H]

COG id: COG2853

COG function: function code M; Surface lipoprotein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaA family [H]

Homologues:

Organism=Escherichia coli, GI1788688, Length=233, Percent_Identity=40.343347639485, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007428 [H]

Pfam domain/function: PF04333 VacJ [H]

EC number: NA

Molecular weight: Translated: 32196; Mature: 32196

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTIRISQAVLAVTAAAALSGCATVQTPTKGDPFEGFNRTMYTFNDKVDQYALKPVARGY
CCEEEHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCC
QWAVPQPMRDSVTNFFSNIGDVYIAANNLVQLKIADGVGDIMRVVINTVFGVGGLFDVAT
EECCCCCHHHHHHHHHHHCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHH
LAKLPKHANDFGVTLGHYGVPSGPYLVLPLLGPSTVRDTAGLAVDYAGNPLTYVRPDSVS
HHHCCCCCCHHCEEECCCCCCCCCEEEEECCCCCHHHHCCCEEEEECCCCEEEECCCCCC
WGLFGLNLVNTRANLLGAGDVLEAAAIDKYSFVRNAYLQRRQALIGGGAGAQSNLPDYGN
CCEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
EAPPPNYEMPEEGAAAPASGAAAAPAASGAPAVAAPAAASAPNPSSATNVPAQQVVPPSP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHCCCCCC
GGIHWPSIRLH
CCCCCCCEEEC
>Mature Secondary Structure
MQTIRISQAVLAVTAAAALSGCATVQTPTKGDPFEGFNRTMYTFNDKVDQYALKPVARGY
CCEEEHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCC
QWAVPQPMRDSVTNFFSNIGDVYIAANNLVQLKIADGVGDIMRVVINTVFGVGGLFDVAT
EECCCCCHHHHHHHHHHHCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHH
LAKLPKHANDFGVTLGHYGVPSGPYLVLPLLGPSTVRDTAGLAVDYAGNPLTYVRPDSVS
HHHCCCCCCHHCEEECCCCCCCCCEEEEECCCCCHHHHCCCEEEEECCCCEEEECCCCCC
WGLFGLNLVNTRANLLGAGDVLEAAAIDKYSFVRNAYLQRRQALIGGGAGAQSNLPDYGN
CCEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
EAPPPNYEMPEEGAAAPASGAAAAPAASGAPAVAAPAAASAPNPSSATNVPAQQVVPPSP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHCCCCCC
GGIHWPSIRLH
CCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]