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The map label for this gene is moeZ [H]

Identifier: 83595122

GI number: 83595122

Start: 4343029

End: 4343844

Strand: Reverse

Name: moeZ [H]

Synonym: Rru_A3793

Alternate gene names: 83595122

Gene position: 4343844-4343029 (Counterclockwise)

Preceding gene: 83595123

Following gene: 83595121

Centisome position: 99.79

GC content: 69.49

Gene sequence:

>816_bases
ATGGATTTCACCGAAGAACAGATCCACCGTTACGCCCGCCATATCCTGCTGCCCGAGGTCGGCGGCACCGGTCAGGCCCG
CCTGCTGGGCGCCCGGGTGCTGGTGGTCGGCGCCGGCGGCCTCGGCTCGCCGCTGGTGCTGTATCTCGCCGCCGCCGGCG
TCGGCACCATCGGCGTCATCGATGCCGATGTCGTCGACCTGTCGAACCTGCAGCGCCAGATCCTGCACACCACCGAGCGC
ATCGGCATGACCAAGGTCGACAGCGCCGCCGCCGCCGTCGCCGCGATCAATCCCGGCGTGCGCCTTGAGACCCACACCGA
GCGGCTGACCGCCGCCAATGCCCTGGAGTTGATCGGCGCCTATGATCTGGTGGCCGATGGCAGCGACAATTTTCCCACCC
GCTTTCTGATCAACGACGCCTGCCACCTGCTGGGCAAGACCCTGGTCAGCGCCGCGGTGCTGCGCTTCGATGGCCAGCTT
TCCACCTTCCGCACCCATCAGGGCGGGCCCTGTTATCGCTGCCTGTACCCCGAGCCGCCACCCGAAGGATCGGTGCCGAC
CTGCGCCGAGGCCGGGGTCCTGGGCGCCGTTGTCGGCACCATGGGCAGCCTGCAGGCGACCGAGGTGATCAAGGAGCTTC
TGGGCATCGGCCGCTCGATGGCCGGGCGGCTGCTGATCTGCGACGCCCTGGCCGGCGGCTTCCGCGAGGTCCGGCTCAAG
CCCGATCCCGCCTGCCCGCTCTGCGGCGCCCAACCGACGATCACCGATCTGTCCCTCCACGCCGATCAGGCCGAGGGATC
CGTCTGTGCCGGGTGA

Upstream 100 bases:

>100_bases
CTCGCCCCAGGCGGGGCGGTGGCTGTTGAACTCGGCGCGGATTCCCGGTAACCCGGGGGTCCGCGCCGTTTTCCCTTTGC
CGTCCTGGATCCCCCCGCCC

Downstream 100 bases:

>100_bases
TCCCGCCGCGCCCGCGCCCGGCATCGCCGGCCTGTCGGCGGTGGTGCTCTCGGATGCCTTCGAGCGCGTCCATTACGCCC
TGGTCCTAGCCAGCGCCGCC

Product: molybdopterin biosynthesis protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MDFTEEQIHRYARHILLPEVGGTGQARLLGARVLVVGAGGLGSPLVLYLAAAGVGTIGVIDADVVDLSNLQRQILHTTER
IGMTKVDSAAAAVAAINPGVRLETHTERLTAANALELIGAYDLVADGSDNFPTRFLINDACHLLGKTLVSAAVLRFDGQL
STFRTHQGGPCYRCLYPEPPPEGSVPTCAEAGVLGAVVGTMGSLQATEVIKELLGIGRSMAGRLLICDALAGGFREVRLK
PDPACPLCGAQPTITDLSLHADQAEGSVCAG

Sequences:

>Translated_271_residues
MDFTEEQIHRYARHILLPEVGGTGQARLLGARVLVVGAGGLGSPLVLYLAAAGVGTIGVIDADVVDLSNLQRQILHTTER
IGMTKVDSAAAAVAAINPGVRLETHTERLTAANALELIGAYDLVADGSDNFPTRFLINDACHLLGKTLVSAAVLRFDGQL
STFRTHQGGPCYRCLYPEPPPEGSVPTCAEAGVLGAVVGTMGSLQATEVIKELLGIGRSMAGRLLICDALAGGFREVRLK
PDPACPLCGAQPTITDLSLHADQAEGSVCAG
>Mature_271_residues
MDFTEEQIHRYARHILLPEVGGTGQARLLGARVLVVGAGGLGSPLVLYLAAAGVGTIGVIDADVVDLSNLQRQILHTTER
IGMTKVDSAAAAVAAINPGVRLETHTERLTAANALELIGAYDLVADGSDNFPTRFLINDACHLLGKTLVSAAVLRFDGQL
STFRTHQGGPCYRCLYPEPPPEGSVPTCAEAGVLGAVVGTMGSLQATEVIKELLGIGRSMAGRLLICDALAGGFREVRLK
PDPACPLCGAQPTITDLSLHADQAEGSVCAG

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=256, Percent_Identity=52.34375, Blast_Score=234, Evalue=5e-62,
Organism=Homo sapiens, GI4885649, Length=161, Percent_Identity=31.6770186335404, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI23510338, Length=193, Percent_Identity=28.4974093264249, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI23510340, Length=193, Percent_Identity=28.4974093264249, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1787048, Length=248, Percent_Identity=41.5322580645161, Blast_Score=187, Evalue=6e-49,
Organism=Escherichia coli, GI87082356, Length=248, Percent_Identity=42.3387096774194, Blast_Score=161, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17540406, Length=247, Percent_Identity=45.3441295546559, Blast_Score=234, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI193203301, Length=163, Percent_Identity=30.6748466257669, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71984476, Length=176, Percent_Identity=31.8181818181818, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321903, Length=257, Percent_Identity=41.2451361867704, Blast_Score=202, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6320598, Length=174, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582879, Length=256, Percent_Identity=48.046875, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24660640, Length=168, Percent_Identity=29.7619047619048, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24641311, Length=216, Percent_Identity=28.2407407407407, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI20129973, Length=173, Percent_Identity=30.635838150289, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 28174; Mature: 28174

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTEEQIHRYARHILLPEVGGTGQARLLGARVLVVGAGGLGSPLVLYLAAAGVGTIGVI
CCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHCCCEEEEE
DADVVDLSNLQRQILHTTERIGMTKVDSAAAAVAAINPGVRLETHTERLTAANALELIGA
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCCCEEECHHHHHHHHHHHHHHHH
YDLVADGSDNFPTRFLINDACHLLGKTLVSAAVLRFDGQLSTFRTHQGGPCYRCLYPEPP
HHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCEEEECCCCCC
PEGSVPTCAEAGVLGAVVGTMGSLQATEVIKELLGIGRSMAGRLLICDALAGGFREVRLK
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHCCCEEEEHHHHCCCEEEEEC
PDPACPLCGAQPTITDLSLHADQAEGSVCAG
CCCCCCCCCCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MDFTEEQIHRYARHILLPEVGGTGQARLLGARVLVVGAGGLGSPLVLYLAAAGVGTIGVI
CCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHCCCEEEEE
DADVVDLSNLQRQILHTTERIGMTKVDSAAAAVAAINPGVRLETHTERLTAANALELIGA
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCCCEEECHHHHHHHHHHHHHHHH
YDLVADGSDNFPTRFLINDACHLLGKTLVSAAVLRFDGQLSTFRTHQGGPCYRCLYPEPP
HHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCEEEECCCCCC
PEGSVPTCAEAGVLGAVVGTMGSLQATEVIKELLGIGRSMAGRLLICDALAGGFREVRLK
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHCCCEEEEHHHHCCCEEEEEC
PDPACPLCGAQPTITDLSLHADQAEGSVCAG
CCCCCCCCCCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]