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The map label for this gene is fur [H]

Identifier: 83595096

GI number: 83595096

Start: 4315983

End: 4316405

Strand: Direct

Name: fur [H]

Synonym: Rru_A3767

Alternate gene names: 83595096

Gene position: 4315983-4316405 (Clockwise)

Preceding gene: 83595095

Following gene: 83595097

Centisome position: 99.15

GC content: 56.97

Gene sequence:

>423_bases
ATGATGTCGAGCATAGAAAAGCGGTGCCTGGAACAGGGCATGAAGATGACCGAGCAGCGTCGGGTCATAGCCCGGGTGTT
GTCGGACGCCGAGGATCACCCGGACGTGGAGGAGGTTTACCGCCGCGCCACCGGAATTGACCCGCGTATTTCGATCGCCA
CCGTCTATCGCACGGTGCGGTTGTTCGAAGAGGCCGGTATCCTGGAGCGGCATGATTTCCGCGATGGCCGGGCGCGCTAT
GAAGAGGTTTCCGAGGATCATCACGATCACCTGATCAATTTGACCACCGGGGACGTGATCGAATTCCATAGTGACCAGAT
CGAGGTCATTCAGCAGGAAATCGCCCGCAAGCTGGGATATCGCTTGATCGGGCACCGTCTGGAACTGTATGGCGTTCCGC
TGGACGATAAAAAGAAAAGCTAA

Upstream 100 bases:

>100_bases
TTTCCGCAAGGCGTCGTGGTGCCATGCCGCGACGCCTTTTCAACACGACCGGCCCAAACTAGTATGAGGCCCGTTGCCGG
AAGCGAGGAATGGGTCGTCC

Downstream 100 bases:

>100_bases
GGGCGGAAGCGTCGTCCGCGCGCCGGTCGGGGCCGCGCGCGGCATATCGTTGGGGTGCTGTATGGGCGTTCTGGGTGATC
TTCGGGCCGGCGGACTTGAA

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MMSSIEKRCLEQGMKMTEQRRVIARVLSDAEDHPDVEEVYRRATGIDPRISIATVYRTVRLFEEAGILERHDFRDGRARY
EEVSEDHHDHLINLTTGDVIEFHSDQIEVIQQEIARKLGYRLIGHRLELYGVPLDDKKKS

Sequences:

>Translated_140_residues
MMSSIEKRCLEQGMKMTEQRRVIARVLSDAEDHPDVEEVYRRATGIDPRISIATVYRTVRLFEEAGILERHDFRDGRARY
EEVSEDHHDHLINLTTGDVIEFHSDQIEVIQQEIARKLGYRLIGHRLELYGVPLDDKKKS
>Mature_140_residues
MMSSIEKRCLEQGMKMTEQRRVIARVLSDAEDHPDVEEVYRRATGIDPRISIATVYRTVRLFEEAGILERHDFRDGRARY
EEVSEDHHDHLINLTTGDVIEFHSDQIEVIQQEIARKLGYRLIGHRLELYGVPLDDKKKS

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=120, Percent_Identity=45, Blast_Score=101, Evalue=2e-23,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16389; Mature: 16389

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSSIEKRCLEQGMKMTEQRRVIARVLSDAEDHPDVEEVYRRATGIDPRISIATVYRTVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
LFEEAGILERHDFRDGRARYEEVSEDHHDHLINLTTGDVIEFHSDQIEVIQQEIARKLGY
HHHHCCCHHHHCCCCHHHHHHHHHHHHHHCEEECCCCCHHHHCHHHHHHHHHHHHHHHHH
RLIGHRLELYGVPLDDKKKS
HHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MMSSIEKRCLEQGMKMTEQRRVIARVLSDAEDHPDVEEVYRRATGIDPRISIATVYRTVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
LFEEAGILERHDFRDGRARYEEVSEDHHDHLINLTTGDVIEFHSDQIEVIQQEIARKLGY
HHHHCCCHHHHCCCCHHHHHHHHHHHHHHCEEECCCCCHHHHCHHHHHHHHHHHHHHHHH
RLIGHRLELYGVPLDDKKKS
HHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9835040 [H]