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The map label for this gene is luxQ [H]

Identifier: 83595085

GI number: 83595085

Start: 4307116

End: 4309134

Strand: Direct

Name: luxQ [H]

Synonym: Rru_A3756

Alternate gene names: 83595085

Gene position: 4307116-4309134 (Clockwise)

Preceding gene: 83595081

Following gene: 83595086

Centisome position: 98.95

GC content: 70.08

Gene sequence:

>2019_bases
ATGCTCCCAGACTCGCCGCAGCCAGACCCGCCCCTGACGGTGCAGGACCTTCTTGATAGCCTTGATGATGACCTGATGGT
GGTCGATGGGGCGGGACGGGTGATCTCGACCGGGCGGCGCGGCGCCGCCCGCCTGGGGTTGACCGATAAGGCGCAGGCGC
TGGGCTGCGATCCCTTCGCCCTGTTGCCCCCCGATGTGGCGACGGGGCGGCGCTCCGCCCTGGCCCGGGTGGTCGCGTGC
TGTGTGGCCGAAACCCTCGAAGATCGCCACGATGGTCACTGGTGGTCGGTGCGGATGATCCCTTTGATCGAAAGGGCGGC
GGCCGGCCGGCCGGAAAGCCGGGCCGAGGACCGTCTGGCGCGGGCGGTGATCTTGCGGATTCGCGATGTCACCGGCACCC
GCGCCCTGGCCCTGGCCCTGGGCGATAGCGAGGAGCGCTTTCGCGGCACCTTTGATGCCGCCGGCCATGGCATGGCCCTG
ATCGATACGGAGGGCCATTTCCGCATGGTCAACCCGATGCTGCGCGCCCTGCTGGGGATCGACGCCGCCCATCCCGGCGA
TCTGGCCGCCGTGGTTTTCCCCGGCGATATCAAGATCGCCATTGATATGATCCGCCGCCTCGCCGCCGAGATCGAACCGT
CGCTGACCGTGCGGTTGCGCTTTGTCGGCGCCGATGGGGCGACGGTCTGGGGGCTGGTCAGCGCCACCTTGCAGCGCCCC
CGGGTGGGCGAGCGCGCCTATGTGGTCATGCATCTGCGCGACATCACCCAGGAGCAACTGGCCGAGGGCCGCCTGCGCGC
CGCCAAGGAAGAGGCCGATCGCGCCAGCCGGGCGAAAACCCGCTTCCTGGCCGCCGCCAGCCACGATCTGCGCCAGCCGT
TGCAGGCGCTCAATATGTTCATCTCGGTGCTGGCCGGGCGTGAAAACGATCCGTGGCGCGCCGCCATCATCGGCAAGATC
GAAAAGACCGCCGACGCCTTGACGGCGCTGCTTGATACCCTGCTCGATATTTCCAAGCTCGATGCCGGGCTGATGCGCTG
CGAGCCGCGCGACGTGATGATCGGCGGGCTGCTTGCCCGCTTGAGCGAGGAATTCCAGCCGCTGGCGGTGTCACGGGGGC
TGGCGTTGCGCGCCGTCGCCTCCAGCGCCGCCGTCCATGCCGATCCGGCCCTGGTGGAAATCGTCCTGCGCAATTTTCTG
GGCAACGCCCTGCGCTATACCCCGAGCGGGCGGGTGCTGGTCGGGGCGCGGCGGCGCGGCGACGGCGTCGAGATCCAGGT
GCTTGATACGGGGCCGGGGATCGCGCCCGAACAGCACGGGTTGATCTTCGAGGATTTTCACCAAGTCGAGAACCCGGCCC
GCGAAAAGGGCGAGGGGCTGGGCCTGGGACTGGCGATCGTCAAACGGGTGGCCCTGCTGCTGGGGGCCCGCGTCGGGGTG
CGGTCGCTGCCCGGGCGCGGGTCGTGTTTCACCATCCGCCTGCCCGGGCCGCAAGGCAGGGCGATCGAGCGCCCCGAGGA
CGGGCTGCTCGGCGTTTCGGCCCAGGCGGCGCGCGGGCTGACCGTGCTGCTGATCGATGACGATCCGGCGGTGCTTGATG
GCCTGACCCTGGTTCTTGAGGCTTGGGATTGCGAGGTGCTGGCCTTCGCCGATCTCGACGGCCTGCGCGAGGGCCTGGGT
TCGGGGGGATTTCTCGCAGCCCCGGATGTGATCCTCAGCGATTTCCGCCTGGGCAAGGGGGAGAACGGCGTCGAGGCGGT
TCGTCTGGTGCGCGATCACTTCGCCCAGGCGGTGCCGGCCCTGCTGCTGACGGGCGATACCGCTCCCCAGCGCTTGCGCG
AAGCCGACGCCAGCGGCCTGCCACTGCTGCATAAGCCGGTCAAGCCCGAGGTTCTGCGCGGCGCCCTGGCCGATGTCATC
GCCGGCGGCCTGACCCTGGATGATGGCCTGCCCGGCGGCGAGGGCGCCGATCCCCGGGCCGTCGGTCCGCCGGGAGGGGG
GGCGGGCGGCGGGCCGTGA

Upstream 100 bases:

>100_bases
AAGAATGCAGTCTTTCGGGTATTTCGGAGGGTCTCGACCTTTCGATCCCAAGCCGTCCGCGGTACAAGGGACGCCGGTCC
GTCCTTCCGGAGTTCACCCC

Downstream 100 bases:

>100_bases
GCGGCCCCCTCTTTGTTTGATTTCCGCAAAACGCCGCCCTCAAGACCATGGCTTGAACCGCCGCGCACGCATACAAACAT
ATCTCAGCCGACGAGACGGG

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 672; Mature: 672

Protein sequence:

>672_residues
MLPDSPQPDPPLTVQDLLDSLDDDLMVVDGAGRVISTGRRGAARLGLTDKAQALGCDPFALLPPDVATGRRSALARVVAC
CVAETLEDRHDGHWWSVRMIPLIERAAAGRPESRAEDRLARAVILRIRDVTGTRALALALGDSEERFRGTFDAAGHGMAL
IDTEGHFRMVNPMLRALLGIDAAHPGDLAAVVFPGDIKIAIDMIRRLAAEIEPSLTVRLRFVGADGATVWGLVSATLQRP
RVGERAYVVMHLRDITQEQLAEGRLRAAKEEADRASRAKTRFLAAASHDLRQPLQALNMFISVLAGRENDPWRAAIIGKI
EKTADALTALLDTLLDISKLDAGLMRCEPRDVMIGGLLARLSEEFQPLAVSRGLALRAVASSAAVHADPALVEIVLRNFL
GNALRYTPSGRVLVGARRRGDGVEIQVLDTGPGIAPEQHGLIFEDFHQVENPAREKGEGLGLGLAIVKRVALLLGARVGV
RSLPGRGSCFTIRLPGPQGRAIERPEDGLLGVSAQAARGLTVLLIDDDPAVLDGLTLVLEAWDCEVLAFADLDGLREGLG
SGGFLAAPDVILSDFRLGKGENGVEAVRLVRDHFAQAVPALLLTGDTAPQRLREADASGLPLLHKPVKPEVLRGALADVI
AGGLTLDDGLPGGEGADPRAVGPPGGGAGGGP

Sequences:

>Translated_672_residues
MLPDSPQPDPPLTVQDLLDSLDDDLMVVDGAGRVISTGRRGAARLGLTDKAQALGCDPFALLPPDVATGRRSALARVVAC
CVAETLEDRHDGHWWSVRMIPLIERAAAGRPESRAEDRLARAVILRIRDVTGTRALALALGDSEERFRGTFDAAGHGMAL
IDTEGHFRMVNPMLRALLGIDAAHPGDLAAVVFPGDIKIAIDMIRRLAAEIEPSLTVRLRFVGADGATVWGLVSATLQRP
RVGERAYVVMHLRDITQEQLAEGRLRAAKEEADRASRAKTRFLAAASHDLRQPLQALNMFISVLAGRENDPWRAAIIGKI
EKTADALTALLDTLLDISKLDAGLMRCEPRDVMIGGLLARLSEEFQPLAVSRGLALRAVASSAAVHADPALVEIVLRNFL
GNALRYTPSGRVLVGARRRGDGVEIQVLDTGPGIAPEQHGLIFEDFHQVENPAREKGEGLGLGLAIVKRVALLLGARVGV
RSLPGRGSCFTIRLPGPQGRAIERPEDGLLGVSAQAARGLTVLLIDDDPAVLDGLTLVLEAWDCEVLAFADLDGLREGLG
SGGFLAAPDVILSDFRLGKGENGVEAVRLVRDHFAQAVPALLLTGDTAPQRLREADASGLPLLHKPVKPEVLRGALADVI
AGGLTLDDGLPGGEGADPRAVGPPGGGAGGGP
>Mature_672_residues
MLPDSPQPDPPLTVQDLLDSLDDDLMVVDGAGRVISTGRRGAARLGLTDKAQALGCDPFALLPPDVATGRRSALARVVAC
CVAETLEDRHDGHWWSVRMIPLIERAAAGRPESRAEDRLARAVILRIRDVTGTRALALALGDSEERFRGTFDAAGHGMAL
IDTEGHFRMVNPMLRALLGIDAAHPGDLAAVVFPGDIKIAIDMIRRLAAEIEPSLTVRLRFVGADGATVWGLVSATLQRP
RVGERAYVVMHLRDITQEQLAEGRLRAAKEEADRASRAKTRFLAAASHDLRQPLQALNMFISVLAGRENDPWRAAIIGKI
EKTADALTALLDTLLDISKLDAGLMRCEPRDVMIGGLLARLSEEFQPLAVSRGLALRAVASSAAVHADPALVEIVLRNFL
GNALRYTPSGRVLVGARRRGDGVEIQVLDTGPGIAPEQHGLIFEDFHQVENPAREKGEGLGLGLAIVKRVALLLGARVGV
RSLPGRGSCFTIRLPGPQGRAIERPEDGLLGVSAQAARGLTVLLIDDDPAVLDGLTLVLEAWDCEVLAFADLDGLREGLG
SGGFLAAPDVILSDFRLGKGENGVEAVRLVRDHFAQAVPALLLTGDTAPQRLREADASGLPLLHKPVKPEVLRGALADVI
AGGLTLDDGLPGGEGADPRAVGPPGGGAGGGP

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=260, Percent_Identity=29.2307692307692, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI87081816, Length=404, Percent_Identity=30.9405940594059, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1788713, Length=303, Percent_Identity=27.0627062706271, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1789149, Length=244, Percent_Identity=29.0983606557377, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI48994928, Length=292, Percent_Identity=27.7397260273973, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1786783, Length=222, Percent_Identity=30.1801801801802, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1786600, Length=253, Percent_Identity=27.2727272727273, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786912, Length=284, Percent_Identity=27.4647887323944, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=31.0185185185185, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1788393, Length=227, Percent_Identity=28.6343612334802, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790861, Length=217, Percent_Identity=30.8755760368664, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1788549, Length=251, Percent_Identity=27.8884462151394, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=204, Percent_Identity=27.4509803921569, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787894, Length=231, Percent_Identity=32.034632034632, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=25.3333333333333, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789403, Length=201, Percent_Identity=31.3432835820896, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71126; Mature: 71126

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPDSPQPDPPLTVQDLLDSLDDDLMVVDGAGRVISTGRRGAARLGLTDKAQALGCDPFA
CCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCEEECCCCCCEECCCCCCHHHCCCCCCE
LLPPDVATGRRSALARVVACCVAETLEDRHDGHWWSVRMIPLIERAAAGRPESRAEDRLA
ECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCHHHHHHHH
RAVILRIRDVTGTRALALALGDSEERFRGTFDAAGHGMALIDTEGHFRMVNPMLRALLGI
HHHHHHHHCCCCCEEEEEEECCCHHHHCCCCCCCCCCEEEEECCCCEEHHHHHHHHHHCC
DAAHPGDLAAVVFPGDIKIAIDMIRRLAAEIEPSLTVRLRFVGADGATVWGLVSATLQRP
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHCCC
RVGERAYVVMHLRDITQEQLAEGRLRAAKEEADRASRAKTRFLAAASHDLRQPLQALNMF
CCCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISVLAGRENDPWRAAIIGKIEKTADALTALLDTLLDISKLDAGLMRCEPRDVMIGGLLAR
HHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LSEEFQPLAVSRGLALRAVASSAAVHADPALVEIVLRNFLGNALRYTPSGRVLVGARRRG
HHHHCCCHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCHHEEECCCCCEEEEECCCC
DGVEIQVLDTGPGIAPEQHGLIFEDFHQVENPAREKGEGLGLGLAIVKRVALLLGARVGV
CCCEEEEEECCCCCCCCCCCCHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
RSLPGRGSCFTIRLPGPQGRAIERPEDGLLGVSAQAARGLTVLLIDDDPAVLDGLTLVLE
CCCCCCCCEEEEECCCCCCCCCCCCCCCCEECCHHHHCCEEEEEECCCCHHHHHHHHHHH
AWDCEVLAFADLDGLREGLGSGGFLAAPDVILSDFRLGKGENGVEAVRLVRDHFAQAVPA
HCCCCEEEECCHHHHHHHCCCCCCEECCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
LLLTGDTAPQRLREADASGLPLLHKPVKPEVLRGALADVIAGGLTLDDGLPGGEGADPRA
EEEECCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCC
VGPPGGGAGGGP
CCCCCCCCCCCC
>Mature Secondary Structure
MLPDSPQPDPPLTVQDLLDSLDDDLMVVDGAGRVISTGRRGAARLGLTDKAQALGCDPFA
CCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCEEECCCCCCEECCCCCCHHHCCCCCCE
LLPPDVATGRRSALARVVACCVAETLEDRHDGHWWSVRMIPLIERAAAGRPESRAEDRLA
ECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCHHHHHHHH
RAVILRIRDVTGTRALALALGDSEERFRGTFDAAGHGMALIDTEGHFRMVNPMLRALLGI
HHHHHHHHCCCCCEEEEEEECCCHHHHCCCCCCCCCCEEEEECCCCEEHHHHHHHHHHCC
DAAHPGDLAAVVFPGDIKIAIDMIRRLAAEIEPSLTVRLRFVGADGATVWGLVSATLQRP
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHCCC
RVGERAYVVMHLRDITQEQLAEGRLRAAKEEADRASRAKTRFLAAASHDLRQPLQALNMF
CCCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISVLAGRENDPWRAAIIGKIEKTADALTALLDTLLDISKLDAGLMRCEPRDVMIGGLLAR
HHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LSEEFQPLAVSRGLALRAVASSAAVHADPALVEIVLRNFLGNALRYTPSGRVLVGARRRG
HHHHCCCHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCHHEEECCCCCEEEEECCCC
DGVEIQVLDTGPGIAPEQHGLIFEDFHQVENPAREKGEGLGLGLAIVKRVALLLGARVGV
CCCEEEEEECCCCCCCCCCCCHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
RSLPGRGSCFTIRLPGPQGRAIERPEDGLLGVSAQAARGLTVLLIDDDPAVLDGLTLVLE
CCCCCCCCEEEEECCCCCCCCCCCCCCCCEECCHHHHCCEEEEEECCCCHHHHHHHHHHH
AWDCEVLAFADLDGLREGLGSGGFLAAPDVILSDFRLGKGENGVEAVRLVRDHFAQAVPA
HCCCCEEEECCHHHHHHHCCCCCCEECCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
LLLTGDTAPQRLREADASGLPLLHKPVKPEVLRGALADVIAGGLTLDDGLPGGEGADPRA
EEEECCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCC
VGPPGGGAGGGP
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA