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The map label for this gene is mrdB [H]

Identifier: 83595008

GI number: 83595008

Start: 4226709

End: 4227839

Strand: Reverse

Name: mrdB [H]

Synonym: Rru_A3679

Alternate gene names: 83595008

Gene position: 4227839-4226709 (Counterclockwise)

Preceding gene: 83595009

Following gene: 83595007

Centisome position: 97.13

GC content: 63.57

Gene sequence:

>1131_bases
GTGGCGAAAAAAGAGCTGCTCGACGAGCCGCTGGTTACGCCCTGGCATGTGGTAGCCTCGCTGCGCATCCACGATATCTT
GTTCCTGCTGGCGCTGGCCTTTCTATCGCTGGTGGGGGCCCTGGCCCTGTTCTCGGCCGCCGGCGGGCGGGCCGATCCCT
GGGCGGACAGCCATCTGATCCGCTTCGGCATCGGTCTCGTCGCCGCCCTGGCCTTGGCCTGCGTCAACGTGCGGCTGATC
ATGCACGCGGCCTATGCCATTTATGGCTTCTTCCTGCTGGCCCTGGTCGGCGTGGCGGTTTTTGGCCATGTCGGCATGGG
GGCCCAGCGCTGGTTGAACCTGGGGGTGGTCGCCGTTCAGCCCTCGGAGTTCATGAAGGTCGGGCTGATCGTGGCTTTGG
CGCGCTATTACCACCACCTGCCCAACGACCGCTGCACCACCTTGCTGGCCGCCTTGCCCGCCGCCTTCCTGACCCTGCTG
CCGGTGGGGCTAGTGTTCTTGCAGCCCAATCTCGGCACCAGCATCCTGCTTGCCGCCACCGGCGGCATCATCGCCCTGCT
CGGCGGTCTGCCGTTATGGACGCTGGTCGTCGCCTTCACCGCCGCCGGTGTCTCGCTGCCGGTGCTGTGGAGCCACATGC
ACGACTACCAGAAGGCCCGGGTTCTGACCTTCCTCAACCCCGAGCGCGATCCCTTGGGGGCGGGCTATAACATCATTCAA
TCGAAGATCGCCCTGGGGTCGGGGGGGATCTGGGGCAAGGGCCTGCTCAACGGCTCGCAAAGCCAGCTTGGCTTCCTGCC
CGAAAAGCACACGGATTTCATCTTCGTGGTCATCGCCGAGGAACTGGGCATGTTCGGCGGCATGCTGATCCTTGGCGCCT
GCTGCGCCATCGTCATTTACGGATACATCGTGGCGGCGCGCACCAAATACGTCTTTGGCCGCCTGTGCGCCGTTGGCGTG
GCCTCGTCGTTCTTTCTGTATGTCTTCGTCAATCTGGCGATGGTCATGGGATTGATCCCGGTGGTCGGCATTCCGCTGCC
TTTGGTATCCTATGGCGGAACGGTGATGATCGCGGTGATGGTTTCGGCGGGTTTGCTGCTGAATATTTCCATTCGGCCGC
GCCTGCGCTGA

Upstream 100 bases:

>100_bases
CTGCGGCCGGCGGACAAAACACCAGACAGCCGTTCCTAGACGGAGCGGCGCCATCATCAAGCGCCCCGCCCTCCGGGGCG
GGGTAGCGGAGTAAAGACGC

Downstream 100 bases:

>100_bases
CCATCGCCCGTCCCCCCAGGCGATTTAGCCCCTAATAATTGAGTTCTTGAGAAGAGGCGCGCCCTCCCCTTATACTTCGG
CGCACCAGGCCCGCGATCAT

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MAKKELLDEPLVTPWHVVASLRIHDILFLLALAFLSLVGALALFSAAGGRADPWADSHLIRFGIGLVAALALACVNVRLI
MHAAYAIYGFFLLALVGVAVFGHVGMGAQRWLNLGVVAVQPSEFMKVGLIVALARYYHHLPNDRCTTLLAALPAAFLTLL
PVGLVFLQPNLGTSILLAATGGIIALLGGLPLWTLVVAFTAAGVSLPVLWSHMHDYQKARVLTFLNPERDPLGAGYNIIQ
SKIALGSGGIWGKGLLNGSQSQLGFLPEKHTDFIFVVIAEELGMFGGMLILGACCAIVIYGYIVAARTKYVFGRLCAVGV
ASSFFLYVFVNLAMVMGLIPVVGIPLPLVSYGGTVMIAVMVSAGLLLNISIRPRLR

Sequences:

>Translated_376_residues
MAKKELLDEPLVTPWHVVASLRIHDILFLLALAFLSLVGALALFSAAGGRADPWADSHLIRFGIGLVAALALACVNVRLI
MHAAYAIYGFFLLALVGVAVFGHVGMGAQRWLNLGVVAVQPSEFMKVGLIVALARYYHHLPNDRCTTLLAALPAAFLTLL
PVGLVFLQPNLGTSILLAATGGIIALLGGLPLWTLVVAFTAAGVSLPVLWSHMHDYQKARVLTFLNPERDPLGAGYNIIQ
SKIALGSGGIWGKGLLNGSQSQLGFLPEKHTDFIFVVIAEELGMFGGMLILGACCAIVIYGYIVAARTKYVFGRLCAVGV
ASSFFLYVFVNLAMVMGLIPVVGIPLPLVSYGGTVMIAVMVSAGLLLNISIRPRLR
>Mature_375_residues
AKKELLDEPLVTPWHVVASLRIHDILFLLALAFLSLVGALALFSAAGGRADPWADSHLIRFGIGLVAALALACVNVRLIM
HAAYAIYGFFLLALVGVAVFGHVGMGAQRWLNLGVVAVQPSEFMKVGLIVALARYYHHLPNDRCTTLLAALPAAFLTLLP
VGLVFLQPNLGTSILLAATGGIIALLGGLPLWTLVVAFTAAGVSLPVLWSHMHDYQKARVLTFLNPERDPLGAGYNIIQS
KIALGSGGIWGKGLLNGSQSQLGFLPEKHTDFIFVVIAEELGMFGGMLILGACCAIVIYGYIVAARTKYVFGRLCAVGVA
SSFFLYVFVNLAMVMGLIPVVGIPLPLVSYGGTVMIAVMVSAGLLLNISIRPRLR

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=339, Percent_Identity=44.5427728613569, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI1786277, Length=326, Percent_Identity=33.7423312883436, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 39999; Mature: 39867

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKELLDEPLVTPWHVVASLRIHDILFLLALAFLSLVGALALFSAAGGRADPWADSHLI
CCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
RFGIGLVAALALACVNVRLIMHAAYAIYGFFLLALVGVAVFGHVGMGAQRWLNLGVVAVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEC
PSEFMKVGLIVALARYYHHLPNDRCTTLLAALPAAFLTLLPVGLVFLQPNLGTSILLAAT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEHH
GGIIALLGGLPLWTLVVAFTAAGVSLPVLWSHMHDYQKARVLTFLNPERDPLGAGYNIIQ
CHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHH
SKIALGSGGIWGKGLLNGSQSQLGFLPEKHTDFIFVVIAEELGMFGGMLILGACCAIVIY
HHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHH
GYIVAARTKYVFGRLCAVGVASSFFLYVFVNLAMVMGLIPVVGIPLPLVSYGGTVMIAVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHH
VSAGLLLNISIRPRLR
HHCCEEEEEEECCCCC
>Mature Secondary Structure 
AKKELLDEPLVTPWHVVASLRIHDILFLLALAFLSLVGALALFSAAGGRADPWADSHLI
CCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
RFGIGLVAALALACVNVRLIMHAAYAIYGFFLLALVGVAVFGHVGMGAQRWLNLGVVAVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEC
PSEFMKVGLIVALARYYHHLPNDRCTTLLAALPAAFLTLLPVGLVFLQPNLGTSILLAAT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEHH
GGIIALLGGLPLWTLVVAFTAAGVSLPVLWSHMHDYQKARVLTFLNPERDPLGAGYNIIQ
CHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHH
SKIALGSGGIWGKGLLNGSQSQLGFLPEKHTDFIFVVIAEELGMFGGMLILGACCAIVIY
HHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHH
GYIVAARTKYVFGRLCAVGVASSFFLYVFVNLAMVMGLIPVVGIPLPLVSYGGTVMIAVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHH
VSAGLLLNISIRPRLR
HHCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]