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The map label for this gene is tagO [H]

Identifier: 83594986

GI number: 83594986

Start: 4198021

End: 4199034

Strand: Reverse

Name: tagO [H]

Synonym: Rru_A3657

Alternate gene names: 83594986

Gene position: 4199034-4198021 (Counterclockwise)

Preceding gene: 83594987

Following gene: 83594985

Centisome position: 96.47

GC content: 71.4

Gene sequence:

>1014_bases
ATGGTCGGGCTGGCGCTGCTGGCGGTCCCGTTAAGCGCGGTGGCCACCGGTTGGCTGCGCCGTGTTCTGCAGGCCCGCAA
GGTTCTTGACACCCCCAACGCCCGCTCCAGCCATTCCGTGCCGACGCCGCGCGGCGGCGGGCTGGCGGTTCTCGCCGTCG
CGCTGGCGCTCTGCGCTGTTGGCTGGCTGGCCGGCGCGCCGGTCGGCTGGCGGCCCTGGGCGCTGCTCGCCGGAGCCATC
GTCCTCGCCGCCCTGTCCTTCGCCGATGACCTGGGCGGACTGGGGGCGGGCAAACGCTTCGCCGTTCAGGCGCTGTGCGT
CGGCCTGGGGCTAGCCGCCCTCCCGGCCGGCGCGCTTGGCCTGGGTGGGCTGCTGCCCGAGGTCCTTGGCGGGCCGCTGG
TCTTCCTGGGCTGGCTATGGTTCGTCAATCTCTATAATTTCATGGATGGCATCGACGGGCTGACCGGGGTGGAAACCCTC
TCGTTGGGCCTGGGAACGGCTTTGGTCGCCGGCTCTGCCGGGATGGCGATGGACCAGATGATGGCCGGGCCGATCCTGGC
CGGGGCGGCGCTCGGCTTTTTGTGGTGGAACTGGCATCCGGCGCGCATCTTCCTCGGCGATGTCGGCAGCGTGCCGCTGG
GCTATCTGCTCGGCGCCCTGCTGGCGGCTTTGGCGGCCGAGGGCCATTTGGCGGCGGCGCTGCTGCTACCGGGCTATTAT
CTGGCCGACGCCACCTTGACCCTTGGCCGGCGGGCGCTGCGCGGGGCCAAGGTGTGGCAGGCCCACCGCGAGCATTTCTA
CCAGCGCGCCACCCAGGGCGGCTGGCCCCACGACCGGGTCAGCCTGTGGGTCGGCGGCTTGAACGGCGTTCTGGCCGGTC
TTGCCCTGTGGTCGACCTTTGATGGCTATGCCCTGCCGGCCCTGGCCGCGGGCATCGTGGCGATCGCCCTGGTGCTGGGA
ACCTTCGCCCGCGCCGGACGCGGCCGGACGCAAGCAAGGGAATACGAGGCGTGA

Upstream 100 bases:

>100_bases
CGGCAGACGGCGGCGGTCTATCGCGCCCTGTTGCCTTGACCGTTGCCCCGACCGGCGTTCCGGGCCTATACCCCTGGCGA
TGGACAATGGCATGGCATGG

Downstream 100 bases:

>100_bases
GAATGCGGTCGCTGTTTACCCCGATGCCGCCCCGGGCGCGCATCGTCTTCGCCCACGACGTGGTGATGGCGGCGCTGTCC
TTCGTGATCTCGCTGTATCT

Product: glycosyl transferase family protein

Products: Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine; UMP [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MVGLALLAVPLSAVATGWLRRVLQARKVLDTPNARSSHSVPTPRGGGLAVLAVALALCAVGWLAGAPVGWRPWALLAGAI
VLAALSFADDLGGLGAGKRFAVQALCVGLGLAALPAGALGLGGLLPEVLGGPLVFLGWLWFVNLYNFMDGIDGLTGVETL
SLGLGTALVAGSAGMAMDQMMAGPILAGAALGFLWWNWHPARIFLGDVGSVPLGYLLGALLAALAAEGHLAAALLLPGYY
LADATLTLGRRALRGAKVWQAHREHFYQRATQGGWPHDRVSLWVGGLNGVLAGLALWSTFDGYALPALAAGIVAIALVLG
TFARAGRGRTQAREYEA

Sequences:

>Translated_337_residues
MVGLALLAVPLSAVATGWLRRVLQARKVLDTPNARSSHSVPTPRGGGLAVLAVALALCAVGWLAGAPVGWRPWALLAGAI
VLAALSFADDLGGLGAGKRFAVQALCVGLGLAALPAGALGLGGLLPEVLGGPLVFLGWLWFVNLYNFMDGIDGLTGVETL
SLGLGTALVAGSAGMAMDQMMAGPILAGAALGFLWWNWHPARIFLGDVGSVPLGYLLGALLAALAAEGHLAAALLLPGYY
LADATLTLGRRALRGAKVWQAHREHFYQRATQGGWPHDRVSLWVGGLNGVLAGLALWSTFDGYALPALAAGIVAIALVLG
TFARAGRGRTQAREYEA
>Mature_337_residues
MVGLALLAVPLSAVATGWLRRVLQARKVLDTPNARSSHSVPTPRGGGLAVLAVALALCAVGWLAGAPVGWRPWALLAGAI
VLAALSFADDLGGLGAGKRFAVQALCVGLGLAALPAGALGLGGLLPEVLGGPLVFLGWLWFVNLYNFMDGIDGLTGVETL
SLGLGTALVAGSAGMAMDQMMAGPILAGAALGFLWWNWHPARIFLGDVGSVPLGYLLGALLAALAAEGHLAAALLLPGYY
LADATLTLGRRALRGAKVWQAHREHFYQRATQGGWPHDRVSLWVGGLNGVLAGLALWSTFDGYALPALAAGIVAIALVLG
TFARAGRGRTQAREYEA

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=307, Percent_Identity=28.9902280130293, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.13 [C]

Molecular weight: Translated: 34630; Mature: 34630

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGLALLAVPLSAVATGWLRRVLQARKVLDTPNARSSHSVPTPRGGGLAVLAVALALCAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
GWLAGAPVGWRPWALLAGAIVLAALSFADDLGGLGAGKRFAVQALCVGLGLAALPAGALG
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHH
LGGLLPEVLGGPLVFLGWLWFVNLYNFMDGIDGLTGVETLSLGLGTALVAGSAGMAMDQM
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
MAGPILAGAALGFLWWNWHPARIFLGDVGSVPLGYLLGALLAALAAEGHLAAALLLPGYY
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCHH
LADATLTLGRRALRGAKVWQAHREHFYQRATQGGWPHDRVSLWVGGLNGVLAGLALWSTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEECCHHHHHHHHHHHHHC
DGYALPALAAGIVAIALVLGTFARAGRGRTQAREYEA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCC
>Mature Secondary Structure
MVGLALLAVPLSAVATGWLRRVLQARKVLDTPNARSSHSVPTPRGGGLAVLAVALALCAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
GWLAGAPVGWRPWALLAGAIVLAALSFADDLGGLGAGKRFAVQALCVGLGLAALPAGALG
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHH
LGGLLPEVLGGPLVFLGWLWFVNLYNFMDGIDGLTGVETLSLGLGTALVAGSAGMAMDQM
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
MAGPILAGAALGFLWWNWHPARIFLGDVGSVPLGYLLGALLAALAAEGHLAAALLLPGYY
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCHH
LADATLTLGRRALRGAKVWQAHREHFYQRATQGGWPHDRVSLWVGGLNGVLAGLALWSTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEECCHHHHHHHHHHHHHC
DGYALPALAAGIVAIALVLGTFARAGRGRTQAREYEA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Undecaprenyl phosphate; UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine [C]

Specific reaction: Undecaprenyl phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine --> Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP [C]

General reaction: Substituted phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]