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The map label for this gene is gpsA

Identifier: 83594900

GI number: 83594900

Start: 4116028

End: 4117077

Strand: Direct

Name: gpsA

Synonym: Rru_A3571

Alternate gene names: 83594900

Gene position: 4116028-4117077 (Clockwise)

Preceding gene: 83594899

Following gene: 83594901

Centisome position: 94.56

GC content: 72.38

Gene sequence:

>1050_bases
ATGAACCAGATCATCGATCATATCGCCGTCATCGGCGGCGGCGCCTGGGGCACCGCGCTTGCCCAGACCTCGCGGCGCGC
CGGCCGGCGGGTAACCTTGTGGGCCCGCGAGCCCGAGGTCGCCCGGGCGATCAACGCCACCCACGAGAACCCGGACTTCC
TGCCCGGCGTCAGCCTTGATCCCGGCCTTCACGCCACCGCCGATCTGGCCGAGGCCCTGCGCGGCGCCGAGGCCGTGCTG
GTGGTCTGCCCGGCCCAGGCCCTGCGCCCGGTGCTGACCACCGCCCGCCCGCTCTGGCCGGGGCGGGCGCCGATGGTGAT
CTGCGCCAAGGGCGTCGAGCAGGGAAGCGGGGCGCGGATGTCGGAAGTGGCCACCGCCGTTCTTCCCGAAGCACCCCTGG
CCGTGCTGTCGGGCCCGACCTTCGCCCGCGAGGTGGCCGAGGGCCGGCCGACGGCGGTCACCCTGGCCTGCGCCGATGGC
GCCCTGGCCGAGGCCCTGGTGTTGGCCCTTGGCACCCGGACCTTCCGCCCCTATGCCTCGACCGATGTGGTCGGCGCCGA
AATTGGCGGGGCGGTCAAGAACGTGCTGGCGATCGCCTGCGGCGTGGTCGAGGGGCTGGGGTTGGGCGACAATGCCCGCG
CCGCCCTGCTGACCCGGGGGCTGGCCGAGATCACCCGCCTGGGCCGGGCCCTTGGCGCGCGGTCGGAAACCCTGTCGGGG
CTGTCGGGTTTGGGCGATCTGATCCTGACGGCGACCAGCATGCAGTCGCGCAACTTCTCGCTGGGCTTCGCCCTTGGTCA
GGGGCGGACCCTTGATCAGGTGCTGGGCGAGCGTCGCTCGGTCGCCGAGGGCGTTCATACCGCTTCGGCGGTGGTCGCCC
TGGCGGCGCGCTGGGCGATCGAAATGCCGATCTGCGCGGCCATCCACGGCGTGCTGTCGGGCGATTACGACGTGACCTCG
GCCATCGAGTCGCTGCTGTCGCGCCCCTTGCGGGTTGAAGGCGGCAGCGAAAGCCAGATCCACCCCACAGCAAAGACCGC
CACGCCCTGA

Upstream 100 bases:

>100_bases
GATGGACGGCGATTTCTGGCCCGACCAAAGCTAGATCAAACTCCGCCGACCGCGCGTCCCGCTTGCGGGACCCGGGGCAA
ATGGGTGATAACCCCGGGTC

Downstream 100 bases:

>100_bases
GAGCAGGCCCGGGATCAAGCCGCCATCGGGACAGATCCGTCTCGCTTCGCCTTGATTCCCGGTCCACGCGGGCTCACATG
CCGTTAGCCGGGGAAGCCGG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MNQIIDHIAVIGGGAWGTALAQTSRRAGRRVTLWAREPEVARAINATHENPDFLPGVSLDPGLHATADLAEALRGAEAVL
VVCPAQALRPVLTTARPLWPGRAPMVICAKGVEQGSGARMSEVATAVLPEAPLAVLSGPTFAREVAEGRPTAVTLACADG
ALAEALVLALGTRTFRPYASTDVVGAEIGGAVKNVLAIACGVVEGLGLGDNARAALLTRGLAEITRLGRALGARSETLSG
LSGLGDLILTATSMQSRNFSLGFALGQGRTLDQVLGERRSVAEGVHTASAVVALAARWAIEMPICAAIHGVLSGDYDVTS
AIESLLSRPLRVEGGSESQIHPTAKTATP

Sequences:

>Translated_349_residues
MNQIIDHIAVIGGGAWGTALAQTSRRAGRRVTLWAREPEVARAINATHENPDFLPGVSLDPGLHATADLAEALRGAEAVL
VVCPAQALRPVLTTARPLWPGRAPMVICAKGVEQGSGARMSEVATAVLPEAPLAVLSGPTFAREVAEGRPTAVTLACADG
ALAEALVLALGTRTFRPYASTDVVGAEIGGAVKNVLAIACGVVEGLGLGDNARAALLTRGLAEITRLGRALGARSETLSG
LSGLGDLILTATSMQSRNFSLGFALGQGRTLDQVLGERRSVAEGVHTASAVVALAARWAIEMPICAAIHGVLSGDYDVTS
AIESLLSRPLRVEGGSESQIHPTAKTATP
>Mature_349_residues
MNQIIDHIAVIGGGAWGTALAQTSRRAGRRVTLWAREPEVARAINATHENPDFLPGVSLDPGLHATADLAEALRGAEAVL
VVCPAQALRPVLTTARPLWPGRAPMVICAKGVEQGSGARMSEVATAVLPEAPLAVLSGPTFAREVAEGRPTAVTLACADG
ALAEALVLALGTRTFRPYASTDVVGAEIGGAVKNVLAIACGVVEGLGLGDNARAALLTRGLAEITRLGRALGARSETLSG
LSGLGDLILTATSMQSRNFSLGFALGQGRTLDQVLGERRSVAEGVHTASAVVALAARWAIEMPICAAIHGVLSGDYDVTS
AIESLLSRPLRVEGGSESQIHPTAKTATP

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=343, Percent_Identity=28.5714285714286, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI24307999, Length=348, Percent_Identity=25.5747126436782, Blast_Score=102, Evalue=4e-22,
Organism=Escherichia coli, GI1790037, Length=339, Percent_Identity=43.0678466076696, Blast_Score=244, Evalue=7e-66,
Organism=Caenorhabditis elegans, GI17507425, Length=351, Percent_Identity=28.7749287749288, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI32564399, Length=347, Percent_Identity=27.0893371757925, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI32564403, Length=356, Percent_Identity=26.123595505618, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI193210136, Length=356, Percent_Identity=26.123595505618, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI193210134, Length=345, Percent_Identity=24.3478260869565, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324513, Length=275, Percent_Identity=32.3636363636364, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320181, Length=274, Percent_Identity=31.3868613138686, Blast_Score=110, Evalue=4e-25,
Organism=Drosophila melanogaster, GI17136200, Length=364, Percent_Identity=28.2967032967033, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17136202, Length=353, Percent_Identity=28.328611898017, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17136204, Length=348, Percent_Identity=28.735632183908, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI45551945, Length=340, Percent_Identity=27.0588235294118, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI22026922, Length=372, Percent_Identity=23.1182795698925, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI281362270, Length=281, Percent_Identity=27.4021352313167, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24648969, Length=301, Percent_Identity=27.2425249169435, Blast_Score=101, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_RHORT (Q2RND0)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_428652.1
- ProteinModelPortal:   Q2RND0
- SMR:   Q2RND0
- STRING:   Q2RND0
- GeneID:   3837027
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A3571
- NMPDR:   fig|1085.1.peg.1925
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   AKGIEHG
- PhylomeDB:   Q2RND0
- ProtClustDB:   PRK00094
- BioCyc:   RRUB269796:RRU_A3571-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 35798; Mature: 35798

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 193-193 BINDING 110-110 BINDING 110-110 BINDING 142-142 BINDING 257-257 BINDING 283-283

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQIIDHIAVIGGGAWGTALAQTSRRAGRRVTLWAREPEVARAINATHENPDFLPGVSLD
CCHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCCCCCCCCCCC
PGLHATADLAEALRGAEAVLVVCPAQALRPVLTTARPLWPGRAPMVICAKGVEQGSGARM
CCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHH
SEVATAVLPEAPLAVLSGPTFAREVAEGRPTAVTLACADGALAEALVLALGTRTFRPYAS
HHHHHHHCCCCCHHHHCCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCC
TDVVGAEIGGAVKNVLAIACGVVEGLGLGDNARAALLTRGLAEITRLGRALGARSETLSG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LSGLGDLILTATSMQSRNFSLGFALGQGRTLDQVLGERRSVAEGVHTASAVVALAARWAI
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMPICAAIHGVLSGDYDVTSAIESLLSRPLRVEGGSESQIHPTAKTATP
CCHHHHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNQIIDHIAVIGGGAWGTALAQTSRRAGRRVTLWAREPEVARAINATHENPDFLPGVSLD
CCHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCCCCCCCCCCC
PGLHATADLAEALRGAEAVLVVCPAQALRPVLTTARPLWPGRAPMVICAKGVEQGSGARM
CCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHH
SEVATAVLPEAPLAVLSGPTFAREVAEGRPTAVTLACADGALAEALVLALGTRTFRPYAS
HHHHHHHCCCCCHHHHCCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCC
TDVVGAEIGGAVKNVLAIACGVVEGLGLGDNARAALLTRGLAEITRLGRALGARSETLSG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LSGLGDLILTATSMQSRNFSLGFALGQGRTLDQVLGERRSVAEGVHTASAVVALAARWAI
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMPICAAIHGVLSGDYDVTSAIESLLSRPLRVEGGSESQIHPTAKTATP
CCHHHHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA