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The map label for this gene is rocD [H]

Identifier: 83594795

GI number: 83594795

Start: 3991197

End: 3992444

Strand: Reverse

Name: rocD [H]

Synonym: Rru_A3466

Alternate gene names: 83594795

Gene position: 3992444-3991197 (Counterclockwise)

Preceding gene: 83594796

Following gene: 83594778

Centisome position: 91.72

GC content: 66.35

Gene sequence:

>1248_bases
ATGACCTCCCTCGCCCCGCCCCTCGCCGCCGGCCTCGCCTCGCCCACCCCCGAGGATCTCCGCGACTATCTGGAGGTCGA
GCATCGCCTGGGCGCGCATAACTACAAGCCGCTTGATGTCGTGCTGACCCGGGGCCAGGGGGTTTGGGTGTGGGATGTCG
CTGGACGGCGTTACCTGGATTGCCTGTCGGCCTATTCGGCGGTCAACCAGGGTCATTGCCATCCGCGCATCCTCGAGGCG
CTGATCGCCCAGGCCGGACGGCTGACCCTGACCAGCCGGGCCTTCCATAACGACCAGTTGGCCCCCTTCTACGAGGAAAT
CTGCGCGCTGACGGGCAGCCACAAGGTGCTGCCGATGAACAGCGGCGCCGAGGCCGTCGAATCGGCGCTGAAATGCGTGC
GCAAATGGGGCTATCGCGAAAAGGGGGTGGCCGAGGATCAGGCCGAGATCATCGTCTGTTCCGACAACTTCCACGGCCGG
ACCATCGCCATCGTCGGCTTTTCCAGCGATCCCGACGCCCGGCGCGATTTTGGCCCCTTCGCGCCGGGCTTCCGCTGCGT
GCCGTTTGGCGACGGCGACGCCCTTGAAGCGGCCATCACGCCCAGAACCGTCGCCGTGCTGATCGAACCGATCCAGGGCG
AGGCCGGGGTGATCATTCCGCCGCCGGGCTACCTGAAACGGGTTCGTGATCTGTGTACGGCCCAAGGCGTCATGCTGATC
CTCGACGAGATCCAGACCGGGCTTGGCCGCACCGGCGCCCTTCTGGCCGAGGAGCACGAGGGGATCGAGGCCGATCTGAC
CCTGGTCGGCAAGGCGCTGTCGGGCGGCTTCTATCCGGTGTCGGCGGTGCTGTCGAATTCCGAGGTTCTGGGCGTGCTGC
GCCCGGGCGAACACGGCAGCACCTTCGGCGGCAATCCCTTGGCCTGCGCCGTGGCGCGGATGGCGCTCAAGGTGCTGGTC
GACGAGGATATGATCGGCAACGCCGCCCGCCAGGGCGCCTATTTCCTTGAGAAGCTGCGCGGCCTGGGCAATCCGCTGAT
CCGCGCGGTGCGGGGCCGCGGCCTGATGCTGGCCGTGGAATTCGCCCCCGAAGCCGGCGGCGCCCGGCCGTTTTGCGAAA
AGCTCAAGGACAAGGGCATCCTTTGCAAGGAGACCCACCGCGACATCATCCGCTTCGCTCCGCCTTTGGTCATCACCGAA
AAAGAAATCGACTGGGCGATGGAACGGATCGCCGAGGTCATCGGTTAA

Upstream 100 bases:

>100_bases
CAGTCGGGGGGCGGGTCCTATTGCATGACCCTGCGCCTTGATCGCCGGGCCCGGGCCGCCGTCCGCGCCACCGCCGCCGC
CGAATAAAGGAGTCCACCCC

Downstream 100 bases:

>100_bases
CCAAGCGCTTTTCCTGATCTTCTAGACCAAAGACTCCTTACCCCCCGGCCCCCCATGCCGGGGGGTTTTTCGCTGTGCGA
GCGGGGGGCGCCGATCAGCG

Product: ornithine--oxo-acid transaminase

Products: NA

Alternate protein names: OAT; Ornithine--oxo-acid aminotransferase [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MTSLAPPLAAGLASPTPEDLRDYLEVEHRLGAHNYKPLDVVLTRGQGVWVWDVAGRRYLDCLSAYSAVNQGHCHPRILEA
LIAQAGRLTLTSRAFHNDQLAPFYEEICALTGSHKVLPMNSGAEAVESALKCVRKWGYREKGVAEDQAEIIVCSDNFHGR
TIAIVGFSSDPDARRDFGPFAPGFRCVPFGDGDALEAAITPRTVAVLIEPIQGEAGVIIPPPGYLKRVRDLCTAQGVMLI
LDEIQTGLGRTGALLAEEHEGIEADLTLVGKALSGGFYPVSAVLSNSEVLGVLRPGEHGSTFGGNPLACAVARMALKVLV
DEDMIGNAARQGAYFLEKLRGLGNPLIRAVRGRGLMLAVEFAPEAGGARPFCEKLKDKGILCKETHRDIIRFAPPLVITE
KEIDWAMERIAEVIG

Sequences:

>Translated_415_residues
MTSLAPPLAAGLASPTPEDLRDYLEVEHRLGAHNYKPLDVVLTRGQGVWVWDVAGRRYLDCLSAYSAVNQGHCHPRILEA
LIAQAGRLTLTSRAFHNDQLAPFYEEICALTGSHKVLPMNSGAEAVESALKCVRKWGYREKGVAEDQAEIIVCSDNFHGR
TIAIVGFSSDPDARRDFGPFAPGFRCVPFGDGDALEAAITPRTVAVLIEPIQGEAGVIIPPPGYLKRVRDLCTAQGVMLI
LDEIQTGLGRTGALLAEEHEGIEADLTLVGKALSGGFYPVSAVLSNSEVLGVLRPGEHGSTFGGNPLACAVARMALKVLV
DEDMIGNAARQGAYFLEKLRGLGNPLIRAVRGRGLMLAVEFAPEAGGARPFCEKLKDKGILCKETHRDIIRFAPPLVITE
KEIDWAMERIAEVIG
>Mature_414_residues
TSLAPPLAAGLASPTPEDLRDYLEVEHRLGAHNYKPLDVVLTRGQGVWVWDVAGRRYLDCLSAYSAVNQGHCHPRILEAL
IAQAGRLTLTSRAFHNDQLAPFYEEICALTGSHKVLPMNSGAEAVESALKCVRKWGYREKGVAEDQAEIIVCSDNFHGRT
IAIVGFSSDPDARRDFGPFAPGFRCVPFGDGDALEAAITPRTVAVLIEPIQGEAGVIIPPPGYLKRVRDLCTAQGVMLIL
DEIQTGLGRTGALLAEEHEGIEADLTLVGKALSGGFYPVSAVLSNSEVLGVLRPGEHGSTFGGNPLACAVARMALKVLVD
EDMIGNAARQGAYFLEKLRGLGNPLIRAVRGRGLMLAVEFAPEAGGARPFCEKLKDKGILCKETHRDIIRFAPPLVITEK
EIDWAMERIAEVIG

Specific function: Catalyzes the interconversion of ornithine to glutamate semialdehyde [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=402, Percent_Identity=51.2437810945274, Blast_Score=414, Evalue=1e-116,
Organism=Homo sapiens, GI284507298, Length=298, Percent_Identity=49.3288590604027, Blast_Score=287, Evalue=1e-77,
Organism=Homo sapiens, GI13994255, Length=435, Percent_Identity=29.1954022988506, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI37574042, Length=421, Percent_Identity=26.8408551068884, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI226442705, Length=421, Percent_Identity=25.8907363420428, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI226442709, Length=390, Percent_Identity=26.6666666666667, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI24119277, Length=418, Percent_Identity=24.8803827751196, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI188536080, Length=428, Percent_Identity=25, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI38679950, Length=428, Percent_Identity=25, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI38679946, Length=428, Percent_Identity=25, Blast_Score=99, Evalue=7e-21,
Organism=Escherichia coli, GI1789759, Length=389, Percent_Identity=35.2185089974293, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1788044, Length=380, Percent_Identity=35.2631578947368, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI145693181, Length=371, Percent_Identity=35.0404312668464, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1789016, Length=409, Percent_Identity=30.8068459657702, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1787560, Length=404, Percent_Identity=31.1881188118812, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1786991, Length=280, Percent_Identity=34.6428571428571, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786349, Length=338, Percent_Identity=27.2189349112426, Blast_Score=98, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI25144271, Length=412, Percent_Identity=49.0291262135922, Blast_Score=417, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI25144274, Length=275, Percent_Identity=47.6363636363636, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI71981843, Length=188, Percent_Identity=48.936170212766, Blast_Score=198, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI32564660, Length=439, Percent_Identity=28.7015945330296, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI71992977, Length=415, Percent_Identity=28.9156626506024, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=465, Percent_Identity=24.7311827956989, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323470, Length=413, Percent_Identity=46.9733656174334, Blast_Score=369, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6324432, Length=396, Percent_Identity=31.0606060606061, Blast_Score=188, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6324386, Length=417, Percent_Identity=24.4604316546763, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6321456, Length=427, Percent_Identity=25.2927400468384, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21357415, Length=389, Percent_Identity=51.9280205655527, Blast_Score=412, Evalue=1e-115,
Organism=Drosophila melanogaster, GI161085790, Length=441, Percent_Identity=29.9319727891156, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI28574759, Length=441, Percent_Identity=30.3854875283447, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21356575, Length=422, Percent_Identity=27.7251184834123, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI281366494, Length=424, Percent_Identity=24.2924528301887, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24667139, Length=424, Percent_Identity=24.2924528301887, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24667143, Length=424, Percent_Identity=24.2924528301887, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.13 [H]

Molecular weight: Translated: 44722; Mature: 44591

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLAPPLAAGLASPTPEDLRDYLEVEHRLGAHNYKPLDVVLTRGQGVWVWDVAGRRYLD
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCHHHHH
CLSAYSAVNQGHCHPRILEALIAQAGRLTLTSRAFHNDQLAPFYEEICALTGSHKVLPMN
HHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEHHCCCCCCCHHHHHHHHHCCCCEEEECC
SGAEAVESALKCVRKWGYREKGVAEDQAEIIVCSDNFHGRTIAIVGFSSDPDARRDFGPF
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEECCCCCCHHCCCCC
APGFRCVPFGDGDALEAAITPRTVAVLIEPIQGEAGVIIPPPGYLKRVRDLCTAQGVMLI
CCCCEEEECCCCCCEEEECCCCEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHCCHHHH
LDEIQTGLGRTGALLAEEHEGIEADLTLVGKALSGGFYPVSAVLSNSEVLGVLRPGEHGS
HHHHHHCCCCCCCHHHHHCCCCEEHHHHHHHHHCCCCCCHHHHHCCCCEEEEECCCCCCC
TFGGNPLACAVARMALKVLVDEDMIGNAARQGAYFLEKLRGLGNPLIRAVRGRGLMLAVE
CCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEE
FAPEAGGARPFCEKLKDKGILCKETHRDIIRFAPPLVITEKEIDWAMERIAEVIG
ECCCCCCCCHHHHHHHHCCCEEHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TSLAPPLAAGLASPTPEDLRDYLEVEHRLGAHNYKPLDVVLTRGQGVWVWDVAGRRYLD
CCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCHHHHH
CLSAYSAVNQGHCHPRILEALIAQAGRLTLTSRAFHNDQLAPFYEEICALTGSHKVLPMN
HHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEHHCCCCCCCHHHHHHHHHCCCCEEEECC
SGAEAVESALKCVRKWGYREKGVAEDQAEIIVCSDNFHGRTIAIVGFSSDPDARRDFGPF
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEECCCCCCHHCCCCC
APGFRCVPFGDGDALEAAITPRTVAVLIEPIQGEAGVIIPPPGYLKRVRDLCTAQGVMLI
CCCCEEEECCCCCCEEEECCCCEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHCCHHHH
LDEIQTGLGRTGALLAEEHEGIEADLTLVGKALSGGFYPVSAVLSNSEVLGVLRPGEHGS
HHHHHHCCCCCCCHHHHHCCCCEEHHHHHHHHHCCCCCCHHHHHCCCCEEEEECCCCCCC
TFGGNPLACAVARMALKVLVDEDMIGNAARQGAYFLEKLRGLGNPLIRAVRGRGLMLAVE
CCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEE
FAPEAGGARPFCEKLKDKGILCKETHRDIIRFAPPLVITEKEIDWAMERIAEVIG
ECCCCCCCCHHHHHHHHCCCEEHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]