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The map label for this gene is cobQ [H]

Identifier: 83594710

GI number: 83594710

Start: 3897342

End: 3898832

Strand: Direct

Name: cobQ [H]

Synonym: Rru_A3381

Alternate gene names: 83594710

Gene position: 3897342-3898832 (Clockwise)

Preceding gene: 83594709

Following gene: 83594712

Centisome position: 89.54

GC content: 70.76

Gene sequence:

>1491_bases
GTGAGCGCGACCGGCCCTTCCCCGCATCATCGCGCCCGTGCCCTGATGATCCAGGGCACGGGGTCCGATGTCGGCAAGTC
GTTGCTGGTCTCCGGTCTGGCCCGCGCCCTGACCCGGCGCGGTCTGCGGGTGGCGCCCTTCAAGGCGCAGAACATGAGCA
ACAACGCCGCCGTCACCGCCGATGGCGGCGAGATCGGCCGCGCCCAGGCCTTGCAGGCGCGGGCTTGCGGGCTGGTCCCC
AGCGTCGATATGAACCCGGTGCTGCTCAAGCCACAAAGCGAGACCGGCAGCCAGTTGATTGTTCAGGGGCGGGTGGCCGG
AACGGTGATGGCCGGGCGATACCGGGCGATGACCGCCACGCTGATGCCCACGGTGCTGGAAAGCTTCGCCCGCCTACGCG
CGGCGGCCGATATCGTCCTGGTCGAAGGGGCGGGCAGCCCCGCCGAGGTCAATCTGCGGGCCGGCGATATCGCCAATATG
GGATTCGCCGAGGCCGCCGATGTGCCGGTGGTCATCGTGGGCGATATCGATCGCGGCGGGGTGATCGCCGCCCTTGTCGG
CACCCATGTGCTGCTGCCCGAGGCCGAGCGGCGGCGGATCGCCGGCTTCCTTATCAACAAGTTTCGCGGCGATGTCGGGC
TGTTCGAACCGGCCCTGGCGGTGATCGAGGGCCATACGGGCTGGGCGCCGCTGGGGGTGATCCCCTGGTTCCCGCGCGCC
AGCGCCCTGCCGGCCGAGGATGCCCAATCGCTGGAGTCGCGGCCGGCGGCGGCGGCAAGGGCCGGGGACGGACGGCTGCG
CATCGTCGTGCCCCGGCTGTCGCGCATCGCCAATTTCGATGATTTCGATCCGCTGATCGCCGAGCCCGATGTCGATCTGC
GCTTCATCGGCGCCGGCGAGGCCCTACCCGGCGATGCCGATCTGGTGATCCTGCCCGGCTCGAAGGCCACCCTTGCCGAT
CTCGCCTTCCTGCGCGCCCAGGGTTGGGACGGCGATCTGCTGGGCCATCACCGGCGCGGCGGGCGCATCCTCGGCCTTTG
CGCCGGCTATCAAATGCTGGGCCGGCGGGTGGCCGATCCGCAAGGGGTGGAAGGCCCCGCCGAGGAGCGCCCCGGCCTTG
GCTTCCTGGATGTCGACACCGTGATGGGCGGGGAAAAGACGCTGACGGCGGTGCGTTTCCGCGATCACCTGTGGGGGGCC
GAGGGCTGGGGCTATGAAATGCATGTCGGGCGAACGCAAGGACCCGATACGCGTACCCCCTGGCTGCACGACGGCAGCGC
CCGCTCGGCCGATGGCCGCGTCCTGGGCGCCTATGTCCACGGCCTGTTCGCCAGCGACGCCTTCCGCCGGGCCTTCCTGG
GCTGGCTGCGCCCCGGCCGAACCGCCGGCATCGCCTATGACGACACGGTCGAGGCGACCCTCGACGCCCTGGCCGATCAC
CTGGAACGCCATGTCGCCCTCGACCGCCTGCTCGCCCTGGCCGCGCCCTGA

Upstream 100 bases:

>100_bases
TGGCCGTTTATGGGGCGGGAACCACCGTGCGCAACGTTCTGTTCGACCGCCGCGTCTCCACGCCGCTGGCGGCCAATCTG
AAGCACCTGCTCGCCAAACA

Downstream 100 bases:

>100_bases
ACGGGCTTGAAAAGCAGGTCAGCGCAAGACGGCGAGGGCGATGGCCAGCAGGGCGATCAGCGCGCCTTCGATCAGGCAGG
CGCTCCGAAACAGCGCCAGA

Product: cobyric acid synthase

Products: ADP; phosphate; adenosylcobyric acid; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MSATGPSPHHRARALMIQGTGSDVGKSLLVSGLARALTRRGLRVAPFKAQNMSNNAAVTADGGEIGRAQALQARACGLVP
SVDMNPVLLKPQSETGSQLIVQGRVAGTVMAGRYRAMTATLMPTVLESFARLRAAADIVLVEGAGSPAEVNLRAGDIANM
GFAEAADVPVVIVGDIDRGGVIAALVGTHVLLPEAERRRIAGFLINKFRGDVGLFEPALAVIEGHTGWAPLGVIPWFPRA
SALPAEDAQSLESRPAAAARAGDGRLRIVVPRLSRIANFDDFDPLIAEPDVDLRFIGAGEALPGDADLVILPGSKATLAD
LAFLRAQGWDGDLLGHHRRGGRILGLCAGYQMLGRRVADPQGVEGPAEERPGLGFLDVDTVMGGEKTLTAVRFRDHLWGA
EGWGYEMHVGRTQGPDTRTPWLHDGSARSADGRVLGAYVHGLFASDAFRRAFLGWLRPGRTAGIAYDDTVEATLDALADH
LERHVALDRLLALAAP

Sequences:

>Translated_496_residues
MSATGPSPHHRARALMIQGTGSDVGKSLLVSGLARALTRRGLRVAPFKAQNMSNNAAVTADGGEIGRAQALQARACGLVP
SVDMNPVLLKPQSETGSQLIVQGRVAGTVMAGRYRAMTATLMPTVLESFARLRAAADIVLVEGAGSPAEVNLRAGDIANM
GFAEAADVPVVIVGDIDRGGVIAALVGTHVLLPEAERRRIAGFLINKFRGDVGLFEPALAVIEGHTGWAPLGVIPWFPRA
SALPAEDAQSLESRPAAAARAGDGRLRIVVPRLSRIANFDDFDPLIAEPDVDLRFIGAGEALPGDADLVILPGSKATLAD
LAFLRAQGWDGDLLGHHRRGGRILGLCAGYQMLGRRVADPQGVEGPAEERPGLGFLDVDTVMGGEKTLTAVRFRDHLWGA
EGWGYEMHVGRTQGPDTRTPWLHDGSARSADGRVLGAYVHGLFASDAFRRAFLGWLRPGRTAGIAYDDTVEATLDALADH
LERHVALDRLLALAAP
>Mature_495_residues
SATGPSPHHRARALMIQGTGSDVGKSLLVSGLARALTRRGLRVAPFKAQNMSNNAAVTADGGEIGRAQALQARACGLVPS
VDMNPVLLKPQSETGSQLIVQGRVAGTVMAGRYRAMTATLMPTVLESFARLRAAADIVLVEGAGSPAEVNLRAGDIANMG
FAEAADVPVVIVGDIDRGGVIAALVGTHVLLPEAERRRIAGFLINKFRGDVGLFEPALAVIEGHTGWAPLGVIPWFPRAS
ALPAEDAQSLESRPAAAARAGDGRLRIVVPRLSRIANFDDFDPLIAEPDVDLRFIGAGEALPGDADLVILPGSKATLADL
AFLRAQGWDGDLLGHHRRGGRILGLCAGYQMLGRRVADPQGVEGPAEERPGLGFLDVDTVMGGEKTLTAVRFRDHLWGAE
GWGYEMHVGRTQGPDTRTPWLHDGSARSADGRVLGAYVHGLFASDAFRRAFLGWLRPGRTAGIAYDDTVEATLDALADHL
ERHVALDRLLALAAP

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: 6.3.5.10

Molecular weight: Translated: 52379; Mature: 52248

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATGPSPHHRARALMIQGTGSDVGKSLLVSGLARALTRRGLRVAPFKAQNMSNNAAVTA
CCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEECCEECCCCCCCEEEEE
DGGEIGRAQALQARACGLVPSVDMNPVLLKPQSETGSQLIVQGRVAGTVMAGRYRAMTAT
CCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCEEEEECCCCEEEECCCHHHHHHH
LMPTVLESFARLRAAADIVLVEGAGSPAEVNLRAGDIANMGFAEAADVPVVIVGDIDRGG
HHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEECCCCCCCCCCHHCCCCEEEEECCCCCC
VIAALVGTHVLLPEAERRRIAGFLINKFRGDVGLFEPALAVIEGHTGWAPLGVIPWFPRA
EEEEEHHCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHEEECCCCCCCCCCCCCCCCC
SALPAEDAQSLESRPAAAARAGDGRLRIVVPRLSRIANFDDFDPLIAEPDVDLRFIGAGE
CCCCCHHHHHHHCCCCHHHCCCCCEEEEEEEHHHHHCCCCCCCCCCCCCCCCEEEEECCC
ALPGDADLVILPGSKATLADLAFLRAQGWDGDLLGHHRRGGRILGLCAGYQMLGRRVADP
CCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCC
QGVEGPAEERPGLGFLDVDTVMGGEKTLTAVRFRDHLWGAEGWGYEMHVGRTQGPDTRTP
CCCCCCHHCCCCCCEEEHHHHCCCCHHEEEEEHHHHHCCCCCCCEEEEECCCCCCCCCCC
WLHDGSARSADGRVLGAYVHGLFASDAFRRAFLGWLRPGRTAGIAYDDTVEATLDALADH
CCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHH
LERHVALDRLLALAAP
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SATGPSPHHRARALMIQGTGSDVGKSLLVSGLARALTRRGLRVAPFKAQNMSNNAAVTA
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEECCEECCCCCCCEEEEE
DGGEIGRAQALQARACGLVPSVDMNPVLLKPQSETGSQLIVQGRVAGTVMAGRYRAMTAT
CCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCEEEEECCCCEEEECCCHHHHHHH
LMPTVLESFARLRAAADIVLVEGAGSPAEVNLRAGDIANMGFAEAADVPVVIVGDIDRGG
HHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEECCCCCCCCCCHHCCCCEEEEECCCCCC
VIAALVGTHVLLPEAERRRIAGFLINKFRGDVGLFEPALAVIEGHTGWAPLGVIPWFPRA
EEEEEHHCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHEEECCCCCCCCCCCCCCCCC
SALPAEDAQSLESRPAAAARAGDGRLRIVVPRLSRIANFDDFDPLIAEPDVDLRFIGAGE
CCCCCHHHHHHHCCCCHHHCCCCCEEEEEEEHHHHHCCCCCCCCCCCCCCCCEEEEECCC
ALPGDADLVILPGSKATLADLAFLRAQGWDGDLLGHHRRGGRILGLCAGYQMLGRRVADP
CCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCC
QGVEGPAEERPGLGFLDVDTVMGGEKTLTAVRFRDHLWGAEGWGYEMHVGRTQGPDTRTP
CCCCCCHHCCCCCCEEEHHHHCCCCHHEEEEEHHHHHCCCCCCCEEEEECCCCCCCCCCC
WLHDGSARSADGRVLGAYVHGLFASDAFRRAFLGWLRPGRTAGIAYDDTVEATLDALADH
CCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHH
LERHVALDRLLALAAP
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; adenosylcobyrinic acid a,c-diamide; L-glutamine; H2O

Specific reaction: 4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H2O = 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA