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The map label for this gene is cobO [H]

Identifier: 83594696

GI number: 83594696

Start: 3884119

End: 3884766

Strand: Direct

Name: cobO [H]

Synonym: Rru_A3367

Alternate gene names: 83594696

Gene position: 3884119-3884766 (Clockwise)

Preceding gene: 83594695

Following gene: 83594698

Centisome position: 89.23

GC content: 66.67

Gene sequence:

>648_bases
ATGTCCGACGATCAGATCCCGCTTGCCGACCCGCCCTTCGATGCCGCCGAGAGCGACGATGCCCGCCACCGCGAGCGCAT
GGCCAAGAAGAAGGTCGTCCGCGACCGCATGCTGGCGAGCAAGGCGACCGCCAAGGGATTGCTGGTCGTTCATACCGGCA
CCGGCAAGGGCAAATCGACCGCCGCCTTCGGCATGGTCCTGCGCTGCATCGGCCACGGCTTTCCCGTCGCCATCGTCCAG
TTCGTCAAAGGCGCCAAGACCACCGCCGAGCGCGATTTTCTGGAAGGCTTCCCCGATCTGGTCACCATCCGCGCCATGGG
CGAGGGCTTCACCTGGGAAACCCAGGACCGCGAGCGCGATATCGCCAGCGCCCGCAAGGCCTGGGAGGTCGCCAAGGGCT
TCCTCGCCGACCCGACCCTGCATATGGTGGTGCTCGACGAGATCAATATCGTGCTGCGCTATGGCTATCTGGAGGTCGCC
GAGGTGATCGACGCCGTCACCGCCCGCCCCGCCGGCCAGCACGCGGTGCTGACCGGGCGCAACGCTCCCGAGGCGCTGAT
CGAGGCCGCCGATCTGGTGACCGAGATGAAGATGATCAAACACCCCTTCCGCGCCGGCATCGGCCCCCAGCCGGGGGTGG
AGTTTTAA

Upstream 100 bases:

>100_bases
GCGCAGTCGGCGCAATGACATGGGCGCGGTGCTAGCGGCCCTGGCCGAAGGCCAAGAGCCCAGCTAGGATATTACCGATC
CTTCTCTGGAAAGGCTGCCG

Downstream 100 bases:

>100_bases
TCTTCCACGCCGTGGGCGCTGGAACGGGCCTTGGTCCATTTGCTGGCTTCGGCCAGGATCCATTCGCGGAAGGCCCGCAC
ACCGGGGCGGGCGAGGTGGC

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MSDDQIPLADPPFDAAESDDARHRERMAKKKVVRDRMLASKATAKGLLVVHTGTGKGKSTAAFGMVLRCIGHGFPVAIVQ
FVKGAKTTAERDFLEGFPDLVTIRAMGEGFTWETQDRERDIASARKAWEVAKGFLADPTLHMVVLDEINIVLRYGYLEVA
EVIDAVTARPAGQHAVLTGRNAPEALIEAADLVTEMKMIKHPFRAGIGPQPGVEF

Sequences:

>Translated_215_residues
MSDDQIPLADPPFDAAESDDARHRERMAKKKVVRDRMLASKATAKGLLVVHTGTGKGKSTAAFGMVLRCIGHGFPVAIVQ
FVKGAKTTAERDFLEGFPDLVTIRAMGEGFTWETQDRERDIASARKAWEVAKGFLADPTLHMVVLDEINIVLRYGYLEVA
EVIDAVTARPAGQHAVLTGRNAPEALIEAADLVTEMKMIKHPFRAGIGPQPGVEF
>Mature_214_residues
SDDQIPLADPPFDAAESDDARHRERMAKKKVVRDRMLASKATAKGLLVVHTGTGKGKSTAAFGMVLRCIGHGFPVAIVQF
VKGAKTTAERDFLEGFPDLVTIRAMGEGFTWETQDRERDIASARKAWEVAKGFLADPTLHMVVLDEINIVLRYGYLEVAE
VIDAVTARPAGQHAVLTGRNAPEALIEAADLVTEMKMIKHPFRAGIGPQPGVEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=196, Percent_Identity=42.3469387755102, Blast_Score=172, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 23437; Mature: 23306

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDQIPLADPPFDAAESDDARHRERMAKKKVVRDRMLASKATAKGLLVVHTGTGKGKST
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHH
AAFGMVLRCIGHGFPVAIVQFVKGAKTTAERDFLEGFPDLVTIRAMGEGFTWETQDRERD
HHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCHHEEEEECCCCCCCCCCHHHHH
IASARKAWEVAKGFLADPTLHMVVLDEINIVLRYGYLEVAEVIDAVTARPAGQHAVLTGR
HHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
NAPEALIEAADLVTEMKMIKHPFRAGIGPQPGVEF
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SDDQIPLADPPFDAAESDDARHRERMAKKKVVRDRMLASKATAKGLLVVHTGTGKGKST
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHH
AAFGMVLRCIGHGFPVAIVQFVKGAKTTAERDFLEGFPDLVTIRAMGEGFTWETQDRERD
HHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCHHEEEEECCCCCCCCCCHHHHH
IASARKAWEVAKGFLADPTLHMVVLDEINIVLRYGYLEVAEVIDAVTARPAGQHAVLTGR
HHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
NAPEALIEAADLVTEMKMIKHPFRAGIGPQPGVEF
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]