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The map label for this gene is gpt [H]

Identifier: 83594648

GI number: 83594648

Start: 3829379

End: 3829936

Strand: Direct

Name: gpt [H]

Synonym: Rru_A3319

Alternate gene names: 83594648

Gene position: 3829379-3829936 (Clockwise)

Preceding gene: 83594646

Following gene: 83594656

Centisome position: 87.97

GC content: 63.98

Gene sequence:

>558_bases
ATGGAAACCAAGGATTACGCCAGCGCGGTCTACATTCCCATCGCCTGGGAATTGTTTCACCGCGACACCCGCAGCCTCGC
CCACAAGCTGATGGCCAAGGGCCCGTTCAAGGGAATCGTCGCCATCACCCGGGGCGGGTTGATTCCCAGTTCGATCATCG
CCCGCGAACTCGATATCCGGGTGATCGAAAGCGTCGGCGTCGCCACCTATGACGATCGCACCCAAAGCACCGGCGTGCAG
ATTCTGAAAGAGCTCAACCGCGATCTGGTCGGCGATGGCGAAGGCTGGCTGGTGGTCGACGATCTGGTCGACAGCGGCGT
CACCGCCCGCGCCGTCAAGGCGATGCTGCCCAAGGCCCATATGGCGACCGTTTACGCCAAGCCCGAGGGTCAGAAGGAAA
CCGACACCTTCGTCGTCGCCGTGCGCCAGGACGTCTGGCTGCTTTTCCCCTGGGACGCCGATCTGCAGCCCAACGAGCCG
CTGGTCCGCCGTCAGCGCGACCTGGAGGTCGATGACGTCAGCATCGGCCGCCCCGACGACATGCCAAGCCAGGGGTGA

Upstream 100 bases:

>100_bases
GACCGCCGGGGGGCGCGTCCAGCCTTCTTGATCGGAAATCGCCGCAGGGATAAAACCGCATCCTGTTTTTCGCCCCCTTG
GGCAAATTAAAGGGCCCCCC

Downstream 100 bases:

>100_bases
TCGTTTCCGGCCGCCCCTTCCACCGGGAAAGGGCGGCCGCCCCACCATCTCGTGAGCGTGAAGCCAATCGTCGTCGCACC
CTGGTCGAGAGGGTCCGGGG

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
METKDYASAVYIPIAWELFHRDTRSLAHKLMAKGPFKGIVAITRGGLIPSSIIARELDIRVIESVGVATYDDRTQSTGVQ
ILKELNRDLVGDGEGWLVVDDLVDSGVTARAVKAMLPKAHMATVYAKPEGQKETDTFVVAVRQDVWLLFPWDADLQPNEP
LVRRQRDLEVDDVSIGRPDDMPSQG

Sequences:

>Translated_185_residues
METKDYASAVYIPIAWELFHRDTRSLAHKLMAKGPFKGIVAITRGGLIPSSIIARELDIRVIESVGVATYDDRTQSTGVQ
ILKELNRDLVGDGEGWLVVDDLVDSGVTARAVKAMLPKAHMATVYAKPEGQKETDTFVVAVRQDVWLLFPWDADLQPNEP
LVRRQRDLEVDDVSIGRPDDMPSQG
>Mature_185_residues
METKDYASAVYIPIAWELFHRDTRSLAHKLMAKGPFKGIVAITRGGLIPSSIIARELDIRVIESVGVATYDDRTQSTGVQ
ILKELNRDLVGDGEGWLVVDDLVDSGVTARAVKAMLPKAHMATVYAKPEGQKETDTFVVAVRQDVWLLFPWDADLQPNEP
LVRRQRDLEVDDVSIGRPDDMPSQG

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786433, Length=145, Percent_Identity=45.5172413793103, Blast_Score=128, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 20542; Mature: 20542

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKDYASAVYIPIAWELFHRDTRSLAHKLMAKGPFKGIVAITRGGLIPSSIIARELDIR
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHH
VIESVGVATYDDRTQSTGVQILKELNRDLVGDGEGWLVVDDLVDSGVTARAVKAMLPKAH
HHHHCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEHHHHCCCHHHHHHHHHCCCCC
MATVYAKPEGQKETDTFVVAVRQDVWLLFPWDADLQPNEPLVRRQRDLEVDDVSIGRPDD
EEEEEECCCCCCCCCEEEEEEECCEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCC
MPSQG
CCCCC
>Mature Secondary Structure
METKDYASAVYIPIAWELFHRDTRSLAHKLMAKGPFKGIVAITRGGLIPSSIIARELDIR
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHH
VIESVGVATYDDRTQSTGVQILKELNRDLVGDGEGWLVVDDLVDSGVTARAVKAMLPKAH
HHHHCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEHHHHCCCHHHHHHHHHCCCCC
MATVYAKPEGQKETDTFVVAVRQDVWLLFPWDADLQPNEPLVRRQRDLEVDDVSIGRPDD
EEEEEECCCCCCCCCEEEEEEECCEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCC
MPSQG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA