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The map label for this gene is metX

Identifier: 83594596

GI number: 83594596

Start: 3765238

End: 3766413

Strand: Direct

Name: metX

Synonym: Rru_A3266

Alternate gene names: 83594596

Gene position: 3765238-3766413 (Clockwise)

Preceding gene: 83594590

Following gene: 83594597

Centisome position: 86.5

GC content: 64.71

Gene sequence:

>1176_bases
ATGAATGTCCTGCCGGCGGCATCCCAACCGCTCAATCAAAGCGTCACGCTGTGCGTCGACGCGCCCATGCGCCTGGACAG
CGGCCTGGAGCTGGGGCCGCTCACCGTGGCCTATCAGACCATCGGTCGCCTCAACGCCGAGCGGACCAACGCCATCTTGA
TATGCCACGCGCTGACCGGCGACCAGCATGTCATCGGTCCCCATCCGGTCACCGGCCGGCCGGGCTGGTGGGAGACCCTG
GTCGGTCCGGGCAAGACCATCGATACCGATCGCTATTTCATCATCTGCTCGAATGTTCTGGGCGGCTGCCTGGGGACCAC
TGGCCCCAAGGAGATCAACCCGGCGACCGGCAAGCCCTGGGGGCTTGGCTTTCCCGTCATCACCATCGGCGACATGGTGC
GCGCCCAGGCCCTGTTGCTCGACCACCTGGGCATCGAGCGGCTGTTTTGCGCCATCGGCGGATCGATGGGGGCGATGCAG
GTGCTGCAATGGGCGGTCAGCTATCCCGAACGGGTGCGCGCCGTGGTGCCGATCGCCGGATCCTGGCGCCATTCGGCCCA
GAACATCGCCTTTCACGAGGTCGGCCGCCAAGCGATCATGGCCGATCCCGATTGGAACGGCGGCGATTACCTGAACCAGG
GCACGGTTCCCCGCCGGGGGCTGGCGGTGGCGCGGATGACGGCGCATATCACCTATCTGTCCGAACCGGCGCTCCAAAGC
AAATTCGGCCGCAAGCTCCAGGACCGCGCCTCGATCACCTATGGCTTCGATGCGGATTTCCAGGTGGAAAGCTATCTGCG
CCATCAGGGGGCGAATTTCGTCAAACGCTTCGACGCCAACAGTTATCTCTACATCACCCGGGCGATGGATTATTTCGATC
TGGCCGCCGAGCATGACGGCGTGCTGGCCCGCGCCTTCCAAGGCACCAAGGTGCGCTTTTGCGTGGTGTCGTTCACCAGC
GACTGGCTGTTCCCCACCGCCGAAAGCCGGGCGGTGGTGCGGGCGATGAACGCGGCAGCGGCCGATGTCAGCTTTGTCGA
AGTCACCACCGACAAGGGCCACGACGCCTTCCTTCTCGACGAGCCCGAGTTCCACGACACCCTTCAGGGCTTCCTTGATG
GCGCGGCCGACATGTTCGGCCTGCCGCGCGGCCTTTTTTCGGGGATCCGTCCATGA

Upstream 100 bases:

>100_bases
ACGTTGACAGACGGGGTACCCCTTTCTAGCAATTCATCCCCCGCCCCCCGTCCCGCCCAAGGCGGGCGGGTCGGCCCGAT
CGGAAGGAAGCAGCGCCGCG

Downstream 100 bases:

>100_bases
CGCCCACCGGCCCCACCGGCGCCATTCGCTATGACCTGCAGCTGATCGCCGACATGGTGACCCCGGGCGCCCGGGTTCTC
GATGTCGGCTGCGGCGAGGG

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MNVLPAASQPLNQSVTLCVDAPMRLDSGLELGPLTVAYQTIGRLNAERTNAILICHALTGDQHVIGPHPVTGRPGWWETL
VGPGKTIDTDRYFIICSNVLGGCLGTTGPKEINPATGKPWGLGFPVITIGDMVRAQALLLDHLGIERLFCAIGGSMGAMQ
VLQWAVSYPERVRAVVPIAGSWRHSAQNIAFHEVGRQAIMADPDWNGGDYLNQGTVPRRGLAVARMTAHITYLSEPALQS
KFGRKLQDRASITYGFDADFQVESYLRHQGANFVKRFDANSYLYITRAMDYFDLAAEHDGVLARAFQGTKVRFCVVSFTS
DWLFPTAESRAVVRAMNAAAADVSFVEVTTDKGHDAFLLDEPEFHDTLQGFLDGAADMFGLPRGLFSGIRP

Sequences:

>Translated_391_residues
MNVLPAASQPLNQSVTLCVDAPMRLDSGLELGPLTVAYQTIGRLNAERTNAILICHALTGDQHVIGPHPVTGRPGWWETL
VGPGKTIDTDRYFIICSNVLGGCLGTTGPKEINPATGKPWGLGFPVITIGDMVRAQALLLDHLGIERLFCAIGGSMGAMQ
VLQWAVSYPERVRAVVPIAGSWRHSAQNIAFHEVGRQAIMADPDWNGGDYLNQGTVPRRGLAVARMTAHITYLSEPALQS
KFGRKLQDRASITYGFDADFQVESYLRHQGANFVKRFDANSYLYITRAMDYFDLAAEHDGVLARAFQGTKVRFCVVSFTS
DWLFPTAESRAVVRAMNAAAADVSFVEVTTDKGHDAFLLDEPEFHDTLQGFLDGAADMFGLPRGLFSGIRP
>Mature_391_residues
MNVLPAASQPLNQSVTLCVDAPMRLDSGLELGPLTVAYQTIGRLNAERTNAILICHALTGDQHVIGPHPVTGRPGWWETL
VGPGKTIDTDRYFIICSNVLGGCLGTTGPKEINPATGKPWGLGFPVITIGDMVRAQALLLDHLGIERLFCAIGGSMGAMQ
VLQWAVSYPERVRAVVPIAGSWRHSAQNIAFHEVGRQAIMADPDWNGGDYLNQGTVPRRGLAVARMTAHITYLSEPALQS
KFGRKLQDRASITYGFDADFQVESYLRHQGANFVKRFDANSYLYITRAMDYFDLAAEHDGVLARAFQGTKVRFCVVSFTS
DWLFPTAESRAVVRAMNAAAADVSFVEVTTDKGHDAFLLDEPEFHDTLQGFLDGAADMFGLPRGLFSGIRP

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=222, Percent_Identity=40.5405405405405, Blast_Score=161, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_RHORT (Q2RP84)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_428348.1
- ProteinModelPortal:   Q2RP84
- SMR:   Q2RP84
- STRING:   Q2RP84
- GeneID:   3836713
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A3266
- NMPDR:   fig|1085.1.peg.907
- eggNOG:   COG2021
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- PhylomeDB:   Q2RP84
- ProtClustDB:   PRK00175
- BioCyc:   RRUB269796:RRU_A3266-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 42656; Mature: 42656

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: ACT_SITE 155-155 ACT_SITE 354-354

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLPAASQPLNQSVTLCVDAPMRLDSGLELGPLTVAYQTIGRLNAERTNAILICHALTG
CCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECC
DQHVIGPHPVTGRPGWWETLVGPGKTIDTDRYFIICSNVLGGCLGTTGPKEINPATGKPW
CCEECCCCCCCCCCCCHHHHCCCCCEECCCCEEEEECHHHHHHHCCCCCCCCCCCCCCCC
GLGFPVITIGDMVRAQALLLDHLGIERLFCAIGGSMGAMQVLQWAVSYPERVRAVVPIAG
CCCCCCEEHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHCCHHHEEEEEECCC
SWRHSAQNIAFHEVGRQAIMADPDWNGGDYLNQGTVPRRGLAVARMTAHITYLSEPALQS
CCCHHHCCHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHEEECCCHHHHH
KFGRKLQDRASITYGFDADFQVESYLRHQGANFVKRFDANSYLYITRAMDYFDLAAEHDG
HHHHHHHHCCCEEECCCCCCHHHHHHHHCCCHHHHHCCCCCEEEEEECCHHHHHHHCCCC
VLARAFQGTKVRFCVVSFTSDWLFPTAESRAVVRAMNAAAADVSFVEVTTDKGHDAFLLD
EEEEECCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCEEEEC
EPEFHDTLQGFLDGAADMFGLPRGLFSGIRP
CCCHHHHHHHHHHHHHHHHCCCHHHHCCCCC
>Mature Secondary Structure
MNVLPAASQPLNQSVTLCVDAPMRLDSGLELGPLTVAYQTIGRLNAERTNAILICHALTG
CCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECC
DQHVIGPHPVTGRPGWWETLVGPGKTIDTDRYFIICSNVLGGCLGTTGPKEINPATGKPW
CCEECCCCCCCCCCCCHHHHCCCCCEECCCCEEEEECHHHHHHHCCCCCCCCCCCCCCCC
GLGFPVITIGDMVRAQALLLDHLGIERLFCAIGGSMGAMQVLQWAVSYPERVRAVVPIAG
CCCCCCEEHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHCCHHHEEEEEECCC
SWRHSAQNIAFHEVGRQAIMADPDWNGGDYLNQGTVPRRGLAVARMTAHITYLSEPALQS
CCCHHHCCHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHEEECCCHHHHH
KFGRKLQDRASITYGFDADFQVESYLRHQGANFVKRFDANSYLYITRAMDYFDLAAEHDG
HHHHHHHHCCCEEECCCCCCHHHHHHHHCCCHHHHHCCCCCEEEEEECCHHHHHHHCCCC
VLARAFQGTKVRFCVVSFTSDWLFPTAESRAVVRAMNAAAADVSFVEVTTDKGHDAFLLD
EEEEECCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCEEEEC
EPEFHDTLQGFLDGAADMFGLPRGLFSGIRP
CCCHHHHHHHHHHHHHHHHCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA