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The map label for this gene is atpE

Identifier: 83594575

GI number: 83594575

Start: 3740053

End: 3740280

Strand: Reverse

Name: atpE

Synonym: Rru_A3245

Alternate gene names: 83594575

Gene position: 3740280-3740053 (Counterclockwise)

Preceding gene: 83594576

Following gene: 83594574

Centisome position: 85.93

GC content: 62.28

Gene sequence:

>228_bases
ATGGACGCTGAAGCCGCGAAGATGATCGGCGCTGGTCTTGCCGCCATTGGCATGATTGGTTCGGGTATTGGCGTTGGCAA
CATCTGGGCCAACCTGATTGCCACCGTCGGCCGCAACCCGGCCGCCAAGAGCACCGTCGAGCTCTACGGCTGGATCGGCT
TCGCCGTTACCGAAGCTATCGCCCTGTTCGCCTTGGTCGTGGCGCTGATCCTGCTGTTCGCCGCCTAA

Upstream 100 bases:

>100_bases
AGGCCGATAGCGCCCCCGGCGCTGTCTTCCGAAATGCTGTCGGTGGCTGAGGCGAGCCCCTCACCCCTGTCCAACTTGGT
TCTTTTGAAAGGGTAAACTC

Downstream 100 bases:

>100_bases
GTCGGCGCGTTCGCCGCAAGCGGTCGGGGCCGCGCGCCGGATCCCGGGGATTTCCCGGGAGCCTCCGGTGCGCGCCCGCC
GCGCGTGGCAGTCTGCCTGT

Product: H+-transporting two-sector ATPase, subunit C

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(0) sector subunit c; F-type ATPase subunit c; F-ATPase subunit c; Lipid-binding protein

Number of amino acids: Translated: 75; Mature: 75

Protein sequence:

>75_residues
MDAEAAKMIGAGLAAIGMIGSGIGVGNIWANLIATVGRNPAAKSTVELYGWIGFAVTEAIALFALVVALILLFAA

Sequences:

>Translated_75_residues
MDAEAAKMIGAGLAAIGMIGSGIGVGNIWANLIATVGRNPAAKSTVELYGWIGFAVTEAIALFALVVALILLFAA
>Mature_75_residues
MDAEAAKMIGAGLAAIGMIGSGIGVGNIWANLIATVGRNPAAKSTVELYGWIGFAVTEAIALFALVVALILLFAA

Specific function: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits

COG id: COG0636

COG function: function code C; F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase C chain family

Homologues:

Organism=Homo sapiens, GI85794840, Length=70, Percent_Identity=48.5714285714286, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI50593533, Length=70, Percent_Identity=48.5714285714286, Blast_Score=68, Evalue=1e-12,
Organism=Homo sapiens, GI50659069, Length=70, Percent_Identity=48.5714285714286, Blast_Score=68, Evalue=2e-12,
Organism=Homo sapiens, GI4885081, Length=70, Percent_Identity=48.5714285714286, Blast_Score=68, Evalue=2e-12,
Organism=Homo sapiens, GI4502301, Length=70, Percent_Identity=48.5714285714286, Blast_Score=68, Evalue=2e-12,
Organism=Homo sapiens, GI50659074, Length=70, Percent_Identity=48.5714285714286, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71996409, Length=71, Percent_Identity=45.0704225352113, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6226533, Length=69, Percent_Identity=50.7246376811594, Blast_Score=67, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24651601, Length=71, Percent_Identity=47.887323943662, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24651603, Length=71, Percent_Identity=47.887323943662, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24651599, Length=71, Percent_Identity=47.887323943662, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPL_RHORT (Q2RPA5)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_428327.1
- ProteinModelPortal:   Q2RPA5
- SMR:   Q2RPA5
- STRING:   Q2RPA5
- GeneID:   3836692
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A3245
- NMPDR:   fig|1085.1.peg.887
- eggNOG:   NOG122998
- HOGENOM:   HBG753983
- OMA:   GIACLGM
- ProtClustDB:   CLSK745232
- BioCyc:   RRUB269796:RRU_A3245-MONOMER
- HAMAP:   MF_01396
- InterPro:   IPR000454
- InterPro:   IPR020537
- InterPro:   IPR002379
- Gene3D:   G3DSA:1.20.20.10
- PRINTS:   PR00124

Pfam domain/function: PF00137 ATP-synt_C; SSF81333 ATPase_F0/V0_c

EC number: 3.6.3.14

Molecular weight: Translated: 7518; Mature: 7518

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00605 ATPASE_C

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12791270)-; HASH(0x11f89558)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAEAAKMIGAGLAAIGMIGSGIGVGNIWANLIATVGRNPAAKSTVELYGWIGFAVTEAI
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ALFALVVALILLFAA
HHHHHHHHHHHHHCH
>Mature Secondary Structure
MDAEAAKMIGAGLAAIGMIGSGIGVGNIWANLIATVGRNPAAKSTVELYGWIGFAVTEAI
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ALFALVVALILLFAA
HHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA